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Author: National Research Council Publisher: National Academies Press ISBN: 0309290600 Category : Nature Languages : en Pages : 57
Book Description
In 1991, the Environmental Protection Agency (EPA) and the Agency for Toxic Substances and Disease Registry (ATSDR) asked the National Research Council (NRC) to provide technical guidance for establishing community emergency exposure levels for extremely hazardous substances (EHSs) pursuant to the Superfund Amendments and Reauthorization Act of 1986. As a result the NRC published Guidelines for Developing Community Emergency Exposure Levels for Hazardous Substances in 1993 and Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Substances in 2001; providing updated procedures, methods, and other guidelines used by the National Advisory Committee (NAC) on Acute Exposure Guideline Levels (AEGLs) for hazardous substances for assessing acute adverse health effects. Stemming from this report the NAC has developed AEGLs for at least 270 EHSs. There are currently three AEGLs: AEGL-1, AEGL-2, and AEGL-3. AEGL-1 is the airborne concentration of a substance above which it is predicted that the general population could experience notable discomfort, irritation, or certain asymptomatic nonsensory effects. These effects are not disabling and are transient and reversible once exposure is stopped. AEGL-2 is the airborne concentration (of a substance above which it is predicted that the general population could experience irreversible, long-lasting adverse health effects or an impaired ability to escape. AEGL-3 is the airborne concentration of a substance above which it is predicted that the general population could experience life threatening health effects or death. On April 22-24 2013, the NRC-established Committee on Acute Exposure Guideline Levels 2013 met to review AEGL documents approved by the NAC. The committee members were selected for their expertise in toxicology, medicine, industrial hygiene, biostatistics, and risk assessment. Twenty-second Interim Report of the Committee on Acute Exposure Guideline Levels presents a review of AEGLs for various chemicals including acrylonitrile, halogen fluorides, tellurium hexafluoride, and thionyl chloride.
Author: National Research Council Publisher: National Academies Press ISBN: 0309263905 Category : Nature Languages : en Pages : 20
Book Description
In 1991, the Environmental Protection Agency (EPA) and the Agency for Toxic Substances and Disease Registry (ATSDR) asked the National Research Council (NRC) to provide technical guidance for establishing community emergency exposure levels for extremely hazardous substances (EHSs) pursuant to the Superfund Amendments and Reauthorization Act of 1986. In response to that request, the NRC published Guidelines for Developing Community Emergency Exposure Levels for Hazardous Substances in 1993. Subsequently, Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Substances was published in 2001; it provided updated procedures, methods, and other guidelines used by the National Advisory Committee (NAC) on Acute Exposure Guideline Levels (AEGLs) for hazardous substances for assessing acute adverse health effects. Using both these reports, the NAC-consisting of members from the EPA, the Department of Defense (DOD), the Department of Energy (DOE), the Department of Transportation (DOT), other federal and state governments, the chemical industry, academia, and other organizations from the private sector-developed AEGLs for approximately 270 EHSs. In 1998, EPA and DOD requested that the NRC independently review the AEGLs developed by NAC. In response to that request, the NRC organized within its Committee on Toxicology the Committee on Acute Exposure Guideline Levels, which prepared this report. This report, Twenty-First Interim Report of the Committee on Acute Exposure Guideline Levels: Part B, summarizes the committee's conclusions and recommendations for improving AEGL documents for several chemicals and chemical classes not mentioned in Twenty-First Interim Report of the Committee on Acute Exposure Guideline Levels: Part A.
Author: Committee on Acute Exposure Guideline Levels Publisher: National Academies Press ISBN: 0309187621 Category : Medical Languages : en Pages : 218
Book Description
The present report is the committee's 19th interim report. It summarizes the committee's conclusions and recommendations for improving NAC's AEGL documents for the following chemicals and chemical classes: acrylonitrile, benzonitrile, boron tribromide, BZ (3-quinuclidinyl benzilate), chloroarsenicals, chloroformates, bis-chloromethylether, chloromethylether, chlorosilanes (26 selected compounds), cyanogen, ethyl mercaptan, hexafluoroacetone, lewisites, mercury vapor, nitric acid, nitric oxide, nitrogen dioxide, nitrogen tetroxide, oleum, phenyl mercaptan, propargyl alcohol, selenium hexafluoride, silane, sulfer trioxide, sulfuric acid, tear gas, tert-octyl mercaptan, tetramethoxy silane, thionyl chloride, trimethoxysilane, trimethylbenzenes (1,2,4-; 1,2,5-;and 1,3,5-TMB), and vinyl chloride.
Author: National Research Council (U.S.). Committee on Acute Exposure Guideline Levels Publisher: ISBN: Category : Hazardous substances Languages : en Pages : 53
Author: National Research Council. Committee on Acute Exposure Guideline Levels Publisher: ISBN: Category : Languages : en Pages :
Book Description
"Exposure to high-priority, acutely toxic chemicals for prolonged periods can potentially manifest into adverse health effects and deadly outcomes. Thus, to identify, review, and interpret relevant toxicological and other scientific data and to develop acute exposure guideline levels (AEGLs), the National Advisory Committee (NAC) established applications for federal, state, and local governments, as well as for the private sector. These guidelines frame emergency-response plans in case extremely hazardous substances (EHSs) are released from accidents or terrorist activities. In 1991, the U.S. Environmental Protection Agency (EPA) and the Agency for Toxic Substances and Disease Registry (ATSDR) asked the National Research Council (NRC) to provide technical guidance for establishing community emergency expose levels for extremely hazardous substances. In response to that request and continued efforts to provide current advisory material, the Twentieth Interim Report of the Committee on Acute Exposure Guideline Levels: Part B is the second of a two part report that reviews the proposed AEGLs for scientific validity, completeness, internal consistency, and conformance to prior National Research Council guideline reports. This report also reviews NAC's research recommendations and identifies additional priorities for research to fill data gaps."--Publisher's website.
Author: National Research Council (U.S.). Committee on Acute Exposure Guideline Levels Publisher: ISBN: 9780309216807 Category : Hazardous substances Languages : en Pages : 0
Book Description
"Exposure to high-priority, acutely toxic chemicals for prolonged periods can potentially manifest into adverse health effects and deadly outcomes. Thus, to identify, review, and interpret relevant toxicological and other scientific data and to develop acute exposure guideline levels (AEGLs), the National Advisory Committee (NAC) established applications for federal, state, and local governments, as well as for the private sector. These guidelines frame emergency-response plans in case extremely hazardous substances (EHSs) are released from accidents or terrorist activities. In 1991, the U.S. Environmental Protection Agency (EPA) and the Agency for Toxic Substances and Disease Registry (ATSDR) asked the National Research Council (NRC) to provide technical guidance for establishing community emergency expose levels for extremely hazardous substances. In response to that request and continued efforts to provide current advisory material, the Twentieth Interim Report of the Committee on Acute Exposure Guideline Levels: Part B is the second of a two part report that reviews the proposed AEGLs for scientific validity, completeness, internal consistency, and conformance to prior National Research Council guideline reports. This report also reviews NAC's research recommendations and identifies additional priorities for research to fill data gaps."--Publisher's website.