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Author: Wellman Ribón Publisher: BoD – Books on Demand ISBN: 9535121391 Category : Medical Languages : en Pages : 242
Book Description
Progress obtained by mycobacteriology in recent years is undeniable with regards to preventing, detecting, and treating cases of tuberculosis, millennial disease that is still present as public health issue worldwide. We present here high-impact research and interest topics related to the application of new methodologies, especially molecular methods for rapid diagnostic such as rapid DST, application of high performance liquid chromatography, molecular epidemiology and molecular diagnostic testing on post mortem. Currently, the constant search for vaccines that prevent the disease is promising through research of the immune response generated by the host towards the bacterium, and the effectiveness that may be achieved from developed vaccines. Another high-impact factor is the one generated by considering tuberculosis as a social disease with an infectious component reflected in research about tuberculosis and human rights. Finally, we present important issues of the pathogen interaction with different hosts. The constant knowledge generation that expands the frontiers of understanding is a key factor for finding solutions and successful activities for public health.
Author: Wellman Ribón Publisher: BoD – Books on Demand ISBN: 9535121391 Category : Medical Languages : en Pages : 242
Book Description
Progress obtained by mycobacteriology in recent years is undeniable with regards to preventing, detecting, and treating cases of tuberculosis, millennial disease that is still present as public health issue worldwide. We present here high-impact research and interest topics related to the application of new methodologies, especially molecular methods for rapid diagnostic such as rapid DST, application of high performance liquid chromatography, molecular epidemiology and molecular diagnostic testing on post mortem. Currently, the constant search for vaccines that prevent the disease is promising through research of the immune response generated by the host towards the bacterium, and the effectiveness that may be achieved from developed vaccines. Another high-impact factor is the one generated by considering tuberculosis as a social disease with an infectious component reflected in research about tuberculosis and human rights. Finally, we present important issues of the pathogen interaction with different hosts. The constant knowledge generation that expands the frontiers of understanding is a key factor for finding solutions and successful activities for public health.
Author: Dorothee Heemskerk Publisher: Springer ISBN: 3319191322 Category : Medical Languages : en Pages : 66
Book Description
This work contains updated and clinically relevant information about tuberculosis. It is aimed at providing a succinct overview of history and disease epidemiology, clinical presentation and the most recent scientific developments in the field of tuberculosis research, with an emphasis on diagnosis and treatment. It may serve as a practical resource for students, clinicians and researchers who work in the field of infectious diseases.
Author: K. Toman Publisher: World Health Organization ISBN: 9241546034 Category : Medical Languages : en Pages : 350
Book Description
This is the second edition of a reference work aimed at all those concerned with dealing with tuberculosis control in developing countries. The book follows in the tradition of Kurt Toman's original work in this field, with the text set out in a question and answer format, grouped under three headings: case detection; treatment, and monitoring. The threat of tuberculosis is still potent, with two million deaths globally. This new edition, containing contributions from a number of experts in this field, addresses the resurgence of tuberculosis, and the emergence of multidrug-resistant bacilli, and the growth of HIV-infected individuals with tuberculosis, as well as recent scientific developments.
Author: William R. Jacobs, Jr. Publisher: John Wiley & Sons ISBN: 1683673050 Category : Medical Languages : en Pages : 1379
Book Description
Can today's innovative practices and molecular tools tame this ancient disease? One third of the world's population is infected with tuberculosis (TB), with about 10 million new cases annually. To combat TB and its agent, Mycobacterium tuberculosis, the World Health Organization launched The End TB Strategy, which aims to slash the suffering and cost of TB by 2035. This makes the second edition of Tuberculosis and the Tubercle Bacillus, edited by Jacobs, McShane, Mizrahi, and Orme, an extremely valuable resource for scientists and clinicians. The editors have gathered their colleagues from around the world to present the latest on the molecular biology of M. tuberculosis and related species, the host-pathogen interactions that enable invasion, and the host's immune response to M. tuberculosis infection. The basic, clinical, and translational research presented in this book supports the goals of WHO's End TB Strategy by driving toward the development of effective vaccines, rapid molecular diagnostics, and anti-TB drugs. Creating an effective tuberculosis vaccine. Understand the innate and adaptive immune response to M. tuberculosis infection, its study in established animal models, and how this information is being used to develop new vaccines against TB. Formulating new antituberculosis drugs. Learn the challenges and methods for evaluating new drugs in preclinical trials with a focus on drugs that work against "persisters" and those that act on the electron transport complex and ATP synthase of M. tuberculosis. Overcoming the challenges of diagnosing tuberculosis. Review new diagnostic tools that are simple, rapid, affordable, specific, sensitive, and safe, including molecular-based diagnostic methods such as GeneXpert MTB/RIF. Using molecular, genomic, and bioinformatics tools to understand the biology and evolution of Mycobacterium. Explore current research on the molecular mechanisms that M. tuberculosis uses to evade the immune system, enter a state of nonreplicating persistence, and become reactivated. The second edition of Tuberculosis and the Tubercle Bacillus presents the latest research on a microorganism that is exquisitely well adapted to its human host. This pathogen continues to confound scientists, clinicians, and public health specialists, who will all find much valuable information in this comprehensive set of reviews.
Author: J.F. Murray Publisher: Karger Medical and Scientific Publishers ISBN: 331806095X Category : Medical Languages : en Pages : 232
Book Description
Tuberculosis (TB) remains the largest cause of adult deaths from any single infectious disease, and ranks among the top 10 causes of death worldwide. When TB and war occur simultaneously, the inevitable consequences are disease, human misery, suffering, and heightened mortality. TB is, therefore, one of the most frequent and deadly diseases to complicate the special circumstances of warfare. Written by internationally acclaimed experts, this book provides a comprehensive analysis of the status of TB before, during and after WWII in the 25 belligerent countries that were chiefly involved. It summarizes the history of TB up to the present day. A special chapter on “Nazi Medicine, Tuberculosis and Genocide” examines the horrendous, inhuman Nazi ideology, which during WWII used TB as a justification for murder, and targeted the disease by eradicating millions who were afflicted by it. The final chapter summarizes the lessons learned from WWII and more recent wars and recommends anti-TB measures for future conflicts. This publication is not only of interest to TB specialists and pulmonologists but also to those interested in public health, infectious diseases, war-related issues and the history of medicine. It should also appeal to nonmedical readers like journalists and politicians.
Author: Institute of Medicine Publisher: National Academies Press ISBN: 0309171946 Category : Medical Languages : en Pages : 288
Book Description
Tuberculosis emerged as an epidemic in the 1600s, began to decline as sanitation improved in the 19th century, and retreated further when effective therapy was developed in the 1950s. TB was virtually forgotten until a recent resurgence in the U.S. and around the worldâ€"ominously, in forms resistant to commonly used medicines. What must the nation do to eliminate TB? The distinguished committee from the Institute of Medicine offers recommendations in the key areas of epidemiology and prevention, diagnosis and treatment, funding and organization of public initiatives, and the U.S. role worldwide. The panel also focuses on how to mobilize policy makers and the public to effective action. The book provides important background on the pathology of tuberculosis, its history and status in the U.S., and the public and private response. The committee explains how the U.S. can act with both self-interest and humanitarianism in addressing the worldwide incidence of TB.
Author: World Health Organization Publisher: ISBN: 9789241502252 Category : Health & Fitness Languages : en Pages : 0
Book Description
"Given the absence of international guidelines on the joint management and control of TB and diabetes, the World Health Organization (WHO) and the International Union Against Tuberculosis and Lung Disease (the Union) identified key questions to be answered and commissioned systematic reviews of studies addressing those questions. A series of expert consultations were organized to assess the findings of the systematic reviews and a guideline group was established to develop this provisional collaborative framework. The framework aims to guide national programmes, clinicians and others engaged in care of patients and prevention and control of diabetes and TB on how to establish a coordinated response to both diseases, at organizational and clinical levels. The framework is based on evidence collated from systematic reviews and existing guidelines on the diagnosis and management of TB and diabetes. The systematic reviews confirmed the weak evidence base for the effectiveness and cost-effectiveness of collaborative interventions. The framework is therefore provisional; several of its recommendations are provisional pending better evidence. In order to provide advice on how to fill the knowledge gaps, the framework includes a list of priority research areas."--Page vii-viii.
Author: Wellman Ribón Publisher: BoD – Books on Demand ISBN: 1789232104 Category : Medical Languages : en Pages : 376
Book Description
This book arose from the combination of diverse areas of knowledge, experience, research, and points of view that try to demonstrate that mycobacteria are a complex science and very relevant to scientific studies that affect the human being in the world. Sophisticated techniques for improving human health do not guarantee that the "battle" against mycobacteria has been won, since tuberculosis, mycobacteriosis, and leprosy are a daily challenge in the world. The book includes contributions made by prestigious experts and research groups in different areas of mycobacteria, and they have contributed new perspectives of their area giving a comprehensive, important, and fascinating emphasis of this field that continues to offer challenges that lead various disciplines to understand their biology and pathogenicity. It is hoped that these chapters will be very useful for learning and discussion.
Author: World Health Organization Publisher: ISBN: 9789241504508 Category : Medical Languages : en Pages : 0
Book Description
"Tuberculosis (TB) affected an estimated 8.7 million people and caused 1.4 million deaths globally in 2011, including 0.5 million women and at least 64 000 children. About 13% of TB occurs among people living with HIV, and TB causes almost a quarter of AIDS deaths. There is evidence of links between TB and noncommunicable diseases such as diabetes mellitus and with determinants of ill-health like tobacco and drug use, alcoholism and malnutrition. TB mostly affects the productive segment of society in their prime. One third of people estimated to have TB are either not reached for diagnosis and treatment by the current health systems or are not being reported. Even in patients who are identified, TB is often diagnosed and treated late. In order to reach the unreached and to find TB patients early in the course of their illness, a wider range of stakeholders already involved in community-based activities needs to be engaged. These include the nongovernmental organizations (NGOs) and other civil society organizations (CSOs) that are active in community-based development, particularly in primary health care, HIV infection and maternal and child health, but have not yet included TB in their priorities and activities. NGOs and other CSOs are non-profit organizations that operate independently from the state and from the private for-profit sector. They include a broad spectrum of entities such as international, national and local NGOs, community-based organizations (CBOs), faith-based organizations (FBOs), patient-based organizations and professional associations. CBOs are membership-based non-profit organizations that are usually self-organized in specific local areas (such as a village) to increase solidarity and mutual support to address specific issues. For example, these include HIV support groups, women's groups, parent-teacher associations and micro-credit village associations. CBO membership is comprised entirely of community members themselves, so these organizations can be considered to represent the community most directly. NGOs and other CSOs engage in activities that range from community mobilization, service delivery, and technical assistance to research and advocacy. The strengths of NGOs and other CSOs active in health care and other development interventions at the community level include their reach and spread and their ability to engage marginalized or remote groups. These organizations have a comparative advantage because of their understanding of the local context. Greater collaboration between NGOs and other CSOs and local and national governments could greatly enhance development outcomes. A more decentralized approach that formally recognizes the critical role of NGOs and other CSOs as partners addressing gaps through support to community-based actions will expand TB prevention, diagnosis, treatment and care activities. Community-based TB activities cover a wide range of activities contributing to prevention, diagnosis, improved treatment adherence and care that positively influence the outcomes of drug-sensitive, drug resistant and HIV-associated TB. The activities also include community mobilization to promote effective communication and participation among community members to generate demand for TB prevention, diagnosis, treatment and care services. While diagnostic tests for TB continue to be performed in clinical settings, for lack of simpler diagnostic methods, community-based TB activities are conducted outside the premises of formal health facilities (e.g. hospitals, health centres and clinics) in community-based structures (e.g. schools, places of worship, congregate settings) and homesteads. Such community-based TB activities could and should be integrated with other community-based activities supporting primary health care services, including those for HIV infection, maternal and child health and noncommunicable diseases to improve synergy and impact. Community-based TB activities utilize community structures and mechanisms through which community members, CBOs and groups interact, coordinate and deliver their responses to the challenges and needs affecting their communities."--Page 1.
Author: Wellman Ribón
Author: Wellman Ribón
Author: Dorothee Heemskerk
Author: K. Toman
Author: William R. Jacobs, Jr.
Author: J.F. Murray
Author: Institute of Medicine
Author: 
Author: World Health Organization
Author: Wellman Ribón
Author: World Health Organization