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Author: Jennifer N. Meyers Publisher: Nova Publishers ISBN: 9781600213755 Category : Cell interaction Languages : en Pages : 270
Book Description
Signal transduction is any process by which a cell converts one kind of signal or stimulus into another. Processes referred to as signal transduction often involve a sequence of biochemical reactions inside the cell, which are carried out by enzymes and linked through second messengers. In many transduction processes, an increasing number of enzymes and other molecules become engaged in the events that proceed from the initial stimulus. Responses of cells to environmental signals, toxins and stressors have profound implications for diverse aspects of human health and disease including development, cystic fibrosis, diabetes, asthma, heart, autoimmune diseases and cancer. The delineation of the signal transduction pathways affected in these and other complex human diseases are likely to present new avenues for therapeutic intervention and understanding of human disease mechanisms.
Author: Jennifer N. Meyers Publisher: Nova Publishers ISBN: 9781600213755 Category : Cell interaction Languages : en Pages : 270
Book Description
Signal transduction is any process by which a cell converts one kind of signal or stimulus into another. Processes referred to as signal transduction often involve a sequence of biochemical reactions inside the cell, which are carried out by enzymes and linked through second messengers. In many transduction processes, an increasing number of enzymes and other molecules become engaged in the events that proceed from the initial stimulus. Responses of cells to environmental signals, toxins and stressors have profound implications for diverse aspects of human health and disease including development, cystic fibrosis, diabetes, asthma, heart, autoimmune diseases and cancer. The delineation of the signal transduction pathways affected in these and other complex human diseases are likely to present new avenues for therapeutic intervention and understanding of human disease mechanisms.
Author: Nickolas O. Grachevsky Publisher: Nova Publishers ISBN: 9781600214875 Category : Medical Languages : en Pages : 330
Book Description
Signal transduction is any process by which a cell converts one kind of signal or stimulus into another. Processes referred to as signal transduction often involve a sequence of biochemical reactions inside the cell, which are carried out by enzymes and linked through second messengers. In many transduction processes, an increasing number of enzymes and other molecules become engaged in the events that proceed from the initial stimulus. Responses of cells to environmental signals, toxins and stressors have profound implications for diverse aspects of human health and disease including development, cystic fibrosis, diabetes, asthma, heart, autoimmune diseases and cancer. The delineation of the signal transduction pathways affected in these and other complex human diseases are likely to present new avenues for therapeutic intervention and understanding of human disease mechanisms.
Author: Masayoshi Yamaguchi Publisher: Nova Biomedical Books ISBN: 9781626182653 Category : Science Languages : en Pages : 230
Book Description
Signal transduction plays a pivotal role in cell regulation. Hormones, cytokines and neurotransmitters bind to their specific receptors in the plasma membranes of cells. The receptors of many hormones are coupled to G-protein coupled signaling pathways. Insulin and growth factors are coupled to receptor-linked kinase. The second messenger is generated in cells once the first messenger binds to the receptors of plasma membranes. Cyclic adenosine monophosphate (cyclic AMP), inositol 1,3,5-triphosphate (IP3) and calcium ion (Ca2+) have been demonstrated to play a role as a second messenger in cells. The pivotal role of Ca2+ in cellular regulation was established with the finding of calmodulin and protein kinase C that modulates the effect of Ca2+ in the regulation of cellular functions. Many receptor classes and their downstream kinases activate Erk, Akt, Stat, Smad, NF-?B and other cascades to regulate gene expression and cellular function. This book provides recent research in the study of the new developments in signaling transduction in cells.
Author: Ari Sitaramayya Publisher: Springer ISBN: 9783662501917 Category : Languages : en Pages : 452
Book Description
Providing an overview of recent developments in the field of signal transduction, this volume emphasizes direct clinical significance. As such, topics like nuclear receptors, apoptosis, growth factors, cell cycles and cancer are examined.
Author: Sundas Fayyaz Publisher: Springer ISBN: 3319715534 Category : Medical Languages : en Pages : 310
Book Description
Cancer is a multifaceted disease and overwhelmingly increasing experimental evidence has helped us to develop a deeper understanding of the role of signal transduction cascades in cancer development and progression. Tissue microarrays and next generation sequencing technologies have assisted us to gather missing pieces of jigsaw puzzle and we now know that deregulation of spatio-temporally controlled signaling cascades play fundamental role in metastasis and resistance against wide ranging therapeutics. This book offers a balanced overview of the rapidly emerging cutting edge research in molecular oncology and good source of knowledge for established oncologists, basic and medical students and pharmaceutical industry associated R&D departments.
Author: Gavin McAlpine Publisher: Nova Publishers ISBN: 9781600213762 Category : Cell division Languages : en Pages : 256
Book Description
Signal transduction is any process by which a cell converts one kind of signal or stimulus into another. Processes referred to as signal transduction often involve a sequence of biochemical reactions inside the cell, which are carried out by enzymes and linked through second messengers. In many transduction processes, an increasing number of enzymes and other molecules become engaged in the events that proceed from the initial stimulus. Responses of cells to environmental signals, toxins and stressors have profound implications for diverse aspects of human health and disease including development, cystic fibrosis, diabetes, asthma, heart, autoimmune diseases and cancer. The delineation of the signal transduction pathways affected in these and other complex human diseases are likely to present new avenues for therapeutic intervention and understanding of human disease mechanisms.
Author: Bastien D. Gomperts Publisher: Gulf Professional Publishing ISBN: 0080541186 Category : Science Languages : en Pages : 420
Book Description
Signal Transduction is a well-illustrated, coherent look at cellular signaling processes. Beginning with the basics, it explains how cells respond to external cues, hormones, growth factors, cytokines, cell surfaces, etc., and then shows how these inputs are integrated and coordinated. The extensive color artwork provides the reader with a clearer comprehension of key topics, and margin notes are incorporated to highlight milestones in the evolution of signal transduction. This book serves as an invaluable resource for advanced undergraduates, graduate researchers, and established scientists working in cell biology, pharmacology, immunology, and related fields. Coherent, precise text providing insight in depth to a subject that is central to cell biology and fundamental to many areas of biomedicine Extensive conceptual colour artwork assists with the comprehension of key topics Extensive referencing provides an invaluable link to the core and historical literature Margin notes highlighting milestones in the evolution of our understanding of signalling mechanisms
Author: Jonathan W. Boyd Publisher: John Wiley & Sons ISBN: 1119060265 Category : Science Languages : en Pages : 336
Book Description
Covering a key topic due to growing research into the role of signaling mechanisms in toxicology, this book focuses on practical approaches for informatics, big data, and complex data sets. Combines fundamentals / basics with experimental applications that can help those involved in preclinical drug studies and translational research Includes detailed presentations of study methodology and data collection, analysis, and interpretation Discusses tools like experimental design, sample handling, analytical measurement techniques
Author: Bruce R. Yanson Publisher: Nova Publishers ISBN: 9781600213793 Category : Cell interaction Languages : en Pages : 282
Book Description
In many transduction processes, an increasing number of enzymes and other molecules become engaged in the events that proceed from the initial stimulus. In such cases the chain of steps is referred to as a "signalling cascade" or a "second messenger pathway" and often results in a small stimulus eliciting a large response. Hormones and other signalling molecules may exit the sending cell by exocytosis or other means of membrane transport. The sending cell is typically of a specialised type. Its recipients may be of one type or several, as in the case of insulin, which triggers diverse and systemic effects. This book sheds new light in this exciting field of cell transportation research.
Author: Jennifer N. Meyers
Author: Jennifer N. Meyers
Author: Nickolas O. Grachevsky
Author: Masayoshi Yamaguchi
Author: Ari Sitaramayya
Author: Sundas Fayyaz
Author: Gavin McAlpine
Author: Bastien D. Gomperts
Author: Jonathan W. Boyd
Author: Bruce R. Yanson
Author: Barry L. Brown