Author:
Publisher:
ISBN:
Category : Carcinogens
Languages : en
Pages : 440

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Book Description

Author: Ashutosh Kumar
Publisher: Academic Press
ISBN: 0128092602
Category : Science
Languages : en
Pages : 352

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Book Description
Mutagenicity: Assays and Applications presents an extensive examination of the detection, assessment and future of mutagenicity, particularly as it concerns human health and the environment. Chapters focused on specific types of mutagens or testing methods for their detection collectively explore the current state of human and environmental mutagenesis, future perspectives and regulatory needs. The test procedures for measuring mutagenicity, their advantages and limitations are described with practical and procedural detail, along with their presentation and data processing aspects. It is an essential reference covering the breadth and depth of the field of mutagenicity studies and regulation. By providing both important introductory material and practical assays and applications, this book is useful to graduate students, academic and industry researchers and regulators at various stages of their careers, leading to improved risk assessment and regulation. - Presents an up-to-date and in-depth review of the current state of mutagenesis research - Draws upon the combined experience and expertise of an international group of highly respected editors and chapter authors - Provides an introduction to the concept of mutagenesis with particular consideration given to novel chemicals and materials

Author: Ray Proudlock
Publisher: Academic Press
ISBN: 0128010061
Category : Medical
Languages : en
Pages : 458

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Book Description
Genetic Toxicology Testing: A Laboratory Manual presents a practical guide to genetic toxicology testing of chemicals in a GLP environment. The most commonly used assays are described, from laboratory and test design to results analysis. In a methodical manner, individual test methods are described step-by-step, along with equipment, suggested suppliers, recipes for reagents, and evaluation criteria. An invaluable resource in the lab, this book will help to troubleshoot any assay problems you may encounter to optimise quality and efficiency in your genetic toxicology tests. Genetic Toxicology Testing: A Laboratory Manual is an essential reference for those new to the genetic toxicology laboratory, or anyone involved in setting up their own. - Offers practical and consistent guidance on the most commonly-performed tests and procedures in a genetic toxicology lab - Describes standard genetic toxicology assays, their methodology, reagents, suppliers, and analysis of their results - Includes guidance on general approaches: formulation for in vitro assays, study monitoring, and Good Laboratory Practice (GLP) - Serves as an essential reference for those new to the genetic toxicology laboratory, or anyone involved in setting up their own lab

Author:
Publisher:
ISBN:
Category : Environmental health
Languages : en
Pages : 360

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Book Description

Author: A. Kappas
Publisher: Springer Science & Business Media
ISBN: 1461538084
Category : Medical
Languages : en
Pages : 276

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Book Description
The 19th annual meeting of the European Environmental Mutagen Society was held in Rhodes, Greece, from October 21st to 26th, 1989. The programme was chosen to explore what is currently known about the mechanisms of mutagenesis and carcinogenesis, induced by environmental agents, and the questions regarding the relationship of these two processes. Recent findings, techniques and methodologies in the area of biomonitoring of humans exposed to environmental mutagens-carcinogens were presented and considerable attention was also paid to the aspects and issues of collaborative environmental policy. Researchers from allover the world contributed to the programme of the meeting with posters and oral presentations, providing a variety of new data and interesting scientific approaches. A number of outstanding scientists were invited to present the results of their work. It is only their presenta tions which are included in this book, covering the following topics: Mutations and carcinogenesis; mechanisms of chemical ly-induced genetic effects on molecular, chromosomal and cell division level; adaptability and repair mechanisms; chemical carcinogenesis and oncogenes; structure and metabolism of mutagens-carcinogens; biomonitoring and epidemiology of humans exposed to environmental mutagens-carcinogens. For the sake of evaluating and controlling the mutagenic and carcinogenic potential of our environment it is indispens able to understand the mechanisms and processes by which chemicals act on the genetic material, causing either heredi tary disease or cancer. The pUblication of these proceedings will hopefully contribute to this task.

Author: Sonia Soloneski
Publisher:
ISBN: 9781839621673
Category : DNA repair
Languages : en
Pages :

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Author:
Publisher:
ISBN:
Category : Carcinogenesis
Languages : en
Pages : 260

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Book Description

Author: Roy H. Burdon
Publisher: CRC Press
ISBN: 1482268043
Category : Science
Languages : en
Pages : 265

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Book Description
Genes and the Environment is concerned with genes and how their structures and activities can be influenced by current relevant environmental adversitises. The book aims to provide a brief, integrated coverage at a biochemical and molecular biological level of the various effects that environmental factors can have on our genes, and those of other

Author:
Publisher:
ISBN:
Category : Environmental engineering
Languages : en
Pages : 732

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Book Description

Author:
Publisher:
ISBN:
Category : Environmental engineering
Languages : en
Pages : 740

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Book Description