Travaux scientifiques de François Jacob PDF Download

Author: François Jacob
Publisher: Odile Jacob
ISBN: 9782738109675
Category : Bacterial genetics
Languages : en
Pages : 816

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Author: Oren Harman
Publisher: University of Chicago Press
ISBN: 022607854X
Category : Science
Languages : en
Pages : 387

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Outsider Scientists describes the transformative role played by “outsiders” in the growth of the modern life sciences. Biology, which occupies a special place between the exact and human sciences, has historically attracted many thinkers whose primary training was in other fields: mathematics, physics, chemistry, linguistics, philosophy, history, anthropology, engineering, and even literature. These outsiders brought with them ideas and tools that were foreign to biology, but which, when applied to biological problems, helped to bring about dramatic, and often surprising, breakthroughs. This volume brings together eighteen thought-provoking biographical essays of some of the most remarkable outsiders of the modern era, each written by an authority in the respective field. From Noam Chomsky using linguistics to answer questions about brain architecture, to Erwin Schrödinger contemplating DNA as a physicist would, to Drew Endy tinkering with Biobricks to create new forms of synthetic life, the outsiders featured here make clear just how much there is to gain from disrespecting conventional boundaries. Innovation, it turns out, often relies on importing new ideas from other fields. Without its outsiders, modern biology would hardly be recognizable.

Author: Hans-Jörg Rheinberger
Publisher: Duke University Press
ISBN: 0822391333
Category : Science
Languages : en
Pages : 353

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An Epistemology of the Concrete brings together case studies and theoretical reflections on the history and epistemology of the life sciences by Hans-Jörg Rheinberger, one of the world’s foremost philosophers of science. In these essays, he examines the history of experiments, concepts, model organisms, instruments, and the gamut of epistemological, institutional, political, and social factors that determine the actual course of the development of knowledge. Building on ideas from his influential book Toward a History of Epistemic Things, Rheinberger first considers ways of historicizing scientific knowledge, and then explores different configurations of genetic experimentation in the first half of the twentieth century and the interaction between apparatuses, experiments, and concept formation in molecular biology in the second half of the twentieth century. He delves into fundamental epistemological issues bearing on the relationship between instruments and objects of knowledge, laboratory preparations as a special class of epistemic objects, and the note-taking and write-up techniques used in research labs. He takes up topics ranging from the French “historical epistemologists” Gaston Bachelard and Georges Canguilhem to the liquid scintillation counter, a radioactivity measuring device that became a crucial tool for molecular biology and biomedicine in the 1960s and 1970s. Throughout An Epistemology of the Concrete, Rheinberger shows how assemblages—historical conjunctures—set the conditions for the emergence of epistemic novelty, and he conveys the fascination of scientific things: those organisms, spaces, apparatuses, and techniques that are transformed by research and that transform research in turn.

Author: Patrick Drouin
Publisher: John Benjamins Publishing Company
ISBN: 9027265437
Category : Language Arts & Disciplines
Languages : en
Pages : 268

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The aim of the present volume is to provide a present-day take on variation in terminology by looking forward and examining what leading scholars in the field are working on and where they are taking research in the field today. This reader is built around three themes arranged according to complementary points of view to stimulate thought on the subject of variation as it is approached today. The first theme, “The social dimension of variation”, includes three contributions dealing with variation across different categories of speakers. This reflects not only the expert/layperson dichotomy but also other more original polarities as the emotional dimension and the issue of diastratic variation across LSPs. The second part of this reader puts forward different tools and methods to identify, describe and manage term variation. The third theme of this reader questions semantics of term variation through the topics of concept saturation, multidimensionality and metaphor. Variation, through this picture of current studies, proves to be the touchstone for the understanding of the major issues of terminology research today. The included papers draw on research in terminology carried out in different language communities - Spanish, French, Portuguese, Italian and Dutch in particular - thereby opening up a window on much of the research carried out in these cultural areas.

Author: Gregory R. Bock
Publisher: John Wiley & Sons
ISBN: 9780470319406
Category : Science
Languages : en
Pages : 300

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Much recent research in evolutionary developmental biology has focused on the origin of new body plans. However, most evolutionary change at the population and species level consists of tinkering: small-scale alterations in developmental pathways within a single body plan. Such microevolutionary events have been well studied on a population genetic level and from the perspective of adaptive phenotypic evolution, but their developmental mechanisms remain poorly studied. This book explores both theoretical and practical issues of tinkering. It features a wide range of perspectives to address several fundamental questions. How does tinkering occur developmentally, and how is it manifested phenotypically? Are the developmental mechanisms by which tinkering occur different from those that underlie larger evolutionary changes? What are the developmental constraints on tinkering? And how do we test hypotheses about microevolutionary shifts in development from the fossil record? With contributions from experts in a range of fields, this fascinating book makes exciting reading for anyone studying evolution, developmental biology or genetics.

Author: Francesco Vitale
Publisher: SUNY Press
ISBN: 1438468857
Category : Philosophy
Languages : en
Pages : 258

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Analyzes Derrida’s 1975 seminar “La vie la mort” as a deconstruction of biology with relevance to his work more broadly. In Biodeconstruction,Francesco Vitale demonstrates the key role that the question of life plays in Jacques Derrida’s work. In the seminar La vie la mort (1975), Derrida engages closely with the life sciences, especially biology and evolution theory. Connecting this line of thought to his analysis of cybernetics in Of Grammatology, Vitale shows how Derrida develops a notion of biological life as itself a sort of text that is necessarily open onto further articulations and grafts. This sets the stage for the deconstruction of the traditional opposition between life and death, conceiving of death as an internal condition of the constitution of the living rather than being the opposite of life. It also provides the basis for the deconstruction of the rigidly deterministic concept of the genetic program, an insight that anticipates recent achievements of biological research in epigenetics and sexual reproduction. Finally, Vitaleargues that this framework can enrich our understanding of Derrida’s late work devoted to political issues, connecting his use of the autoimmunitarian lexicon to the theory of cellular suicide in biology. “This book is extremely interesting and engaging, and provides a very original and timely perspective on Derrida’s work. Its greatest strength is bringing together Derrida’s ‘deconstruction’ in his analysis of the life sciences under the heading of ‘biodeconstruction.’ This term is simple but ingenious, and captures beautifully the material dimension of Derrida’s work.” — Nicole Anderson, author of Derrida: Ethics Under Erasure

Author: Ernesto Di Mauro
Publisher: John Wiley & Sons
ISBN: 1789451655
Category : Science
Languages : en
Pages : 276

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Origin of Life studies have a nearly-impossible goal: understanding nature through the comprehension of its origins and its complexities. As a growing field with poorly-defined borders, Origin of Life studies profit from progress in other disciplines. This book proposes both an overview of this large area and an in-depth look at the opinions and results obtained by some of the active contributors of this fascinating and deeply thought-provoking matter. The topics are presented in a bottom-up order, first touching on the habitability of the universe, then the rationale behind meaningful prebiotic chemistry, the possible or probable prebiotic chemical frames, the problem of chirality, and moving on through the role of minerals in biogenesis, biogenic fertile environments, the in-and-out problem as solved by vesicles physics, the evolution of the codes, the structure of LUCA and its proto metabolisms and the meaning of complex extant biological biomorphs, as exemplified by viroids. These topics and the reasoning within the chapters are provided against the backdrop of the evolution of information and complexity.

Author:
Publisher: Odile Jacob
ISBN: 2738186726
Category :
Languages : en
Pages : 513

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Author: Peter Keating
Publisher: MIT Press
ISBN: 9780262112765
Category : Computers
Languages : en
Pages : 574

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An examination of postwar medicine based on the notion of the biomedical platform--the theoretical and clinical meeting ground between the normal and the pathological.

Author: Marie-Odile Soyer-Gobillard
Publisher: Cambridge Scholars Publishing
ISBN: 1527555542
Category : Science
Languages : en
Pages : 247

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This book explores the life, work and careers of two lovers of marine biology and protists, Edouard Chatton (1883-1947) and his exceptional pupil André Lwoff (1902-1994), later a Nobel Prize winner. Offering descriptions of their discoveries and explanations of their artistic talents, it also presents (annotated in numbers for the first time) the beautiful educational course boards made by Chatton for his students and collaborators. This book will appeal to scientists, biologists, parasitologists, researchers, teachers, and students, and is a tribute to these two great scientists.