Author: Silva Lyman Publisher: American Medical Publishers ISBN: Category : Health & Fitness Languages : en Pages : 0
Book Description
Neuroimmunology is a field that combines neuroscience, the study of the nervous system and immunology, the study of the immune system, into one discipline within this field neuroimmunology. The interaction of these two complex systems is studied the neuroimmunologists throughout development, homeostasis, and response to injuries. The adaptive and innate immune systems continuously monitor the nervous system. The immune system identifies and responds to changes in cell identity and neural connectivity during development and adult life. The immune system and nervous system require suitable degrees of cellular differentiation, organizational integrity, and neural network connectivity. Pro-inflammatory cytokines which are released by activated macrophages and monocytes during infection, can impact neural targets that control thermogenesis, behavior, sleep, and mood. Cytokines are produced in the central nervous system due to brain injury, during bacterial and viral infections, and neurodegenerative processes. This book is a valuable compilation of topics, ranging from the basic to the most complex advancements in the field of translational neuroimmunology. It includes contributions of experts and scientists which will provide innovative insights on neuroimmunology and its clinical applications. This book will provide comprehensive knowledge to the readers.
Author: Ruth Arnon Publisher: Academic Press ISBN: 0128020075 Category : Science Languages : en Pages : 504
Book Description
Multiple sclerosis (MS) is the most common disabling neurological disease of young adults. More than 2.3 million people are affected by MS worldwide. Symptoms can vary widely, depending on the localization and amount of the damage induced by combined inflammatory, demyelinating, and neurodegenerative processes. Although a cure for MS does not currently exist, therapies can help treat MS attacks, attenuate disease activity, reduce progress of the disease, and manage symptoms. Translational Neuroimmunology in Multiple Sclerosis provides an overview of recent findings and knowledge of the neuroimmunology of multiple sclerosis, from experimental models and the human disease to the translation of this research to immunotherapeutic strategies. Chapters describe genetic and environmental factors underlying the disease pathogenesis of MS as a basis for development of immunotherapies, immunological markers of disease activity, pharmacogenetics, and responses to therapy. Immunomodulatory therapies currently in practice and future therapeutic strategies on the horizon—such as neuroprotective strategies, stem cells, and repair promotion—are discussed. Contributed by renowned leaders in the field, this cross-disciplinary volume is a great resource for basic scientists and clinical practitioners in neuroscience, neurology, immunology, pharmacology, and in-drug development. Provides an overview of recent findings and knowledge of the neuroimmunology of multiple sclerosis and the translation of this research to immunotherapy treatment Edited by renowned leaders in the field of neuroimmunology and multiple sclerosis Contains the latest resource material for basic and clinical scientists and practitioners in neuroscience, neurology, immunology, and pharmacology
Author: Hiroshi Mitoma Publisher: Springer ISBN: 3030195155 Category : Medical Languages : en Pages : 822
Book Description
A translational overview of neuroimmune diseases for neuroscientists and clinicians that clarifies the pathological mechanisms underlying neuroimmune diseases and builds a comprehensive bridge between the latest research findings and their clinical implications in daily practice. The material is presented in two steps. The first section comprises a review of the pathogenic actions of immune cells in brain diseases. Here the authors discuss the mechanisms through which immune cells disrupt the functions of nerve cells. The second section explores the ways in which the brain becomes dysfunctional due to impaired nerve cell function. Based on pathogenesis, diagnostic and therapeutic strategies are discussed for each clinical category. The book will be invaluable for use in clinical practice of neuroimmune diseases
Author: Sandra Amor Publisher: Frontiers Media SA ISBN: 2889662950 Category : Medical Languages : en Pages : 253
Book Description
The 14th International Congress of Neuroimmunology, ISNI 2018, was held in August 2018 in Brisbane, Australia, and is a biennial event organized by the International Society of Neuroimmunology (ISNI). The theme of ISNI 2018 was “Travelling the Neuroimmunological Translational Highway”, and the Congress highlighted many research discoveries that bridge the gap between basic and clinical sciences, and which impact our understanding of pathogenic immune-mediated mechanisms in diseases affecting the nervous system. In this Research Topic, we aim to give a comprehensive overview of topics highlighted at the Congress, showcasing the current state of the field of neuroimmunology and where it is going in the near future.
Author: Syed A. Rizvi Publisher: Springer Science & Business Media ISBN: 1603278605 Category : Medical Languages : en Pages : 406
Book Description
Clinical Neuroimmunology: Multiple Sclerosis and Related Disorders serves as an indispensable resource for physicians interested in, and dealing with, this very complex and evolving branch of neurology. This comprehensive title provides an introduction to basic neuroimmunology and principles of immunotherapy and also serves as a thorough guide to immune-mediated disorders of the central and peripheral nervous system, as well as other systemic disorders with a significant neuroimmunologic component. The chapters are written by experts in their fields and include the most up to date scientific information. This volume is made to simplify complex immunological mechanisms and to focus on practical patient-related issues. Clinical Neuroimmunology: Multiple Sclerosis and Related Disorders is an invaluable addition to the literature and will be of significant interest to neurologists, residents and fellows, internists, and general practitioners who treat patients with neurologic disorders and other systemic autoimmune diseases.
Author: Nima Rezaei Publisher: Elsevier ISBN: 0323900712 Category : Medical Languages : en Pages : 542
Book Description
Translational NeuroImmunology: Neuroinflammation updates on bench to bedside studies on neurological disorders that have immunological etiologies. The book covers neuroimmunology and the principles of autoimmune and autoinflammatory neurological disorders, with multiple sclerosis as the main focus. The immunopathology, genetics and epigenetics, microbiome, diagnosis and treatment of multiple sclerosis will be explained in ten chapters. A chapter also examines distinct aspects of pericytes, with final discussions on the neurologic manifestations, diagnostic approaches and treatments of the various neuroimmune disorders and lessons learned from translational research on non-human primates and zebrafish. All sections are presented in an accessible, practical format, making this volume a valuable resource for immunologists, neurologists and researchers in translational biomedical research. Gives an introduction on neuroimmunological diseases, from bench to bedside Encourages the development of immunologic approaches to analyze the interaction and specific properties of nervous tissue elements during development and disease Focuses on understanding and therapeutically manipulating immunological responses to injury, degeneration and autoimmunity in the central nervous system Proves changes in relevant immune and inflammatory reactions at the cellular and molecular level during the development of nervous system diseases
Author: Bibiana Bielekova Publisher: Oxford University Press, USA ISBN: 0190050802 Category : Medical Languages : en Pages : 329
Book Description
Neuroimmunology, the latest volume in the Contemporary Neurology Series, provides a practical, clinical, and scientific background on a diverse group of neurological disorders in this rapidly expanding field. The book includes chapters on multiple sclerosis and related disorders in adults and children, neuromyelitis optica spectrum disorder, Guillain-Barre Syndrome, chronic inflammatory demyelinating polyradiculoneuropathy and variants, immune-mediated disorders of the neuromuscular junction, inflammatory myopathies, paraneoplastic disorders and autoimmune encephalitities, and neurologic manifestations of systemic immune-mediated diseases. Unique to the work, the authors have included an introductory chapter on the basics of immunology and another on mechanisms of action of therapies used in neuroimmunologic disorders. The clinical chapters cover epidemiology, pathology, pathogenesis, and pathophysiology of the different diseases along with clinical presentation, diagnostic testing, differential diagnosis, and treatment. All are presented in an accessible, practical format, making this volume a valuable resource for physicians and other healthcare providers that will care for persons with neuroimmunologic diseases.
Author: Jack Antel Publisher: OUP Oxford ISBN: 0191585823 Category : Medical Languages : en Pages : 464
Book Description
Clinical Neurimmunology is the major reference text in the field, providing broad and comprehensive coverage of the interaction between the nervous and immune systems in both normal and diseased states. Understanding this interaction is fundamental to developing therapeutic approaches to disease and injury of the nervous system that are currently only marginally amenable to therapy. Neuroimmunology is a well-recognised and growing specialty world wide, both at the basic science and clinical level. It is a fast moving field and this is the most up to date text available. Chapters are dedicated to the role of the immune system in disorders affecting both the central and peripheral nervous systems, including important neurodegenerative diseases (such as multiple sclerosis and HIV-related neural degeneration) which cause life-long disability. Extensive coverage is given to a whole array of immune-directed therapies. The book has a strong international team of well respected, high profile editors and authors. The first edition published to extensive and positive reviews and has established itself as the principal reference source in the field. This second edition summarizes recent advances in clinical neuroimmunology in a comprehensive and unbiased way.
Author: Amanda L. Piquet Publisher: Springer Nature ISBN: 3030618838 Category : Medical Languages : en Pages : 536
Book Description
This book provides a clinical focus on neuroinflammatory diseases as well as a review in pathophysiology and treatment approaches. Organized into six parts, the book begins with a basic review of the immune system and concepts for learning and treating neuroimmune conditions. The next four sections cover specific subfields of neuroimmunology and autoimmune neurology - the clinical and diagnostic features of multiple sclerosis, other autoimmune conditions of the central nervous system, autoimmune conditions of the peripheral nervous system, and systemic autoimmune conditions that affect the nervous system. To conclude, Section six discusses various clinical approaches to specific presentations in neuroimmunology, including pediatric demyelinating diseases. These sections provide practical clinical information to improve the reader’s knowledge in this complex field. The chapters are written by world renown authors with extensive knowledge to help provide up to date information. The full scope of autoimmune neurology is discussed, which is a unique feature of this book. Neuroimmunology serves as a resource for those in training including residents and fellows to provide clear clinical reasoning and background in a rapidly advancing field.
Author: Bernadette Kalman Publisher: Wiley-Blackwell ISBN: 9781405158404 Category : Medical Languages : en Pages : 0
Book Description
Written by field experts, Neuroimmunology in Clinical Practice fills a void in traditional neuroimmunology literature, which tends to cover the discipline’s scientific aspects with little emphasis on clinical applications. This unique book is essential reading in clinical neuroimmunology. Written by field experts this book provides a comprehensive description of immune mediated neurological disorders complemented with the most pertinent and up to date scientific data Covers inflammatory demyelination in the central nervous system, autoimmune diseases of the peripheral nervous system and the muscle, and disorders of the central and peripheral nervous systems Fills a gap in existing neuroimmunology literature by focusing on clinical applications
Author: Silva Lyman
Author: Ruth Arnon
Author: Hiroshi Mitoma
Author: Sandra Amor
Author: Syed A. Rizvi
Author: Nima Rezaei
Author: Bibiana Bielekova
Author: Jack Antel
Author: Amanda L. Piquet
Author: Bernadette Kalman