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Author: Fobang Liu Publisher: American Chemical Society ISBN: 0841299811 Category : Science Languages : en Pages : 182
Book Description
Atmospheric aerosols, or particulate matter (PM), are liquid or solid particles suspended in the air. Exposure to ambient PM is associated with multiple diseases and accounts for millions of premature deaths today. Although recognized as an important public health problem, PM’s toxicity and toxicological mechanisms are yet to be understood. Various methodologies and assays (i.e., procedures to determine the composition, quantity, or quality of a substance or a mixture) have been developed or employed to understand the components and characteristics of PM that best determine its toxicity. Efforts have also been spent to study the mechanisms of cellular signaling, stress, response, and physiological change, as well as complex multi-tissue effects upon PM exposure. These assays are diverse, spanning from in vitro acellular assays (i.e., chemical assays) to in vitro cellular and in vivo assays. Given that various methodologies and assays have been developed or employed, this digital primer aims to introduce the methodologies and fundamental principles used to study atmospheric aerosols’ toxicity and emerging new techniques. A comprehensive literature review of the scientific findings using these methodologies and assays is not the focus of this primer. The target audiences are senior undergraduates or beginning graduate students unfamiliar with aerosol science and toxicity measurements. An introductory overview of atmospheric aerosols and the motivations to study their toxicity before a detailed discussion of methodologies and assays in the toxicity research of atmospheric aerosols is provided. Beyond this, Toxicity of Atmospheric Aerosols: Methodologies & Assays serves as an assembly of the various methodologies and assays used in the toxicity research of atmospheric aerosols, saving readers time compared to searching from scattered resources.
Author: Fobang Liu Publisher: American Chemical Society ISBN: 0841299811 Category : Science Languages : en Pages : 182
Book Description
Atmospheric aerosols, or particulate matter (PM), are liquid or solid particles suspended in the air. Exposure to ambient PM is associated with multiple diseases and accounts for millions of premature deaths today. Although recognized as an important public health problem, PM’s toxicity and toxicological mechanisms are yet to be understood. Various methodologies and assays (i.e., procedures to determine the composition, quantity, or quality of a substance or a mixture) have been developed or employed to understand the components and characteristics of PM that best determine its toxicity. Efforts have also been spent to study the mechanisms of cellular signaling, stress, response, and physiological change, as well as complex multi-tissue effects upon PM exposure. These assays are diverse, spanning from in vitro acellular assays (i.e., chemical assays) to in vitro cellular and in vivo assays. Given that various methodologies and assays have been developed or employed, this digital primer aims to introduce the methodologies and fundamental principles used to study atmospheric aerosols’ toxicity and emerging new techniques. A comprehensive literature review of the scientific findings using these methodologies and assays is not the focus of this primer. The target audiences are senior undergraduates or beginning graduate students unfamiliar with aerosol science and toxicity measurements. An introductory overview of atmospheric aerosols and the motivations to study their toxicity before a detailed discussion of methodologies and assays in the toxicity research of atmospheric aerosols is provided. Beyond this, Toxicity of Atmospheric Aerosols: Methodologies & Assays serves as an assembly of the various methodologies and assays used in the toxicity research of atmospheric aerosols, saving readers time compared to searching from scattered resources.
Author: National Research Council Publisher: National Academies Press ISBN: 030915233X Category : Nature Languages : en Pages : 465
Book Description
This book is the eighth volume in the series Acute Exposure Guideline Levels for Selected Airborne Chemicals, and reviews AEGLs for acrolein, carbon monoxide, 1,2-dichloroethene, ethylenimine, fluorine, hydrazine, peracetic acid, propylenimine, and sulfur dioxide for scientific accuracy, completeness, and consistency with the NRC guideline reports.
Author: OECD Publisher: OECD Publishing ISBN: 9264071245 Category : Languages : en Pages : 12
Book Description
The bacterial reverse mutation test uses amino-acid requiring at least five strains of Salmonella typhimurium and Escherichia coli to detect point mutations by base substitutions or frameshifts. The principle of this bacterial reverse mutation test ...
Author: Constantin Papastefanou Publisher: Elsevier ISBN: 0080555985 Category : Medical Languages : en Pages : 187
Book Description
Whenever radioactivity is released to the atmosphere, for example by the detonation of nuclear weapons or the testing of nuclear weapons or from nuclear reactor accidents that fraction of it which remains airborne for more than a few hours is liable to be attached to aerosol particles. The resulting radioactive aerosols are carried by atmospheric mixing processes until they settle out or are scavenged by precipitation. The radiation exposure pathway of maximum concern to humans is by inhalation of aerosols and their deposition in the respiratory tract. In this context, it is important to note that radioactive aerosols are commonly of natural origin alos. In particular, the associated radionuclides can be of natural terrestrial origin, such as the decay products of radon gas, or they can e cosmogenic, such as beryllium-7. The exposure of miners of uranium and other ores and minerals to radon and its aerosol-borne decay products is of major significance. The book describes the formation of aerosols, their aerodynamic size distribution, their atmospheric residence time, their sampling and measurement, the range of radioactive aerosols found and studied thus far, including man-made nuclides and radon decay products and their interaction with man, including deposition in the lung and subsequent health effects. Advanced level science handbook for researchers, scientists and academics Covers all aspects of radiation exposure in humans, including subsequent health implications Presents the latest findings and analysis in this highly topical area
Author: Rekha Kale Publisher: Scitus Academics LLC ISBN: 9781681171326 Category : Aerosols Languages : en Pages : 0
Book Description
Atmospheric Aerosols is a vital problem in current environmental research due to its importance in atmospheric optics, energetics, radiative transfer studies, chemistry, climate, biology and public health. Aerosols can influence the energy balance of the terrestrial atmosphere, the hydrological cycle, atmospheric dynamics and monsoon circulations. Because of the heterogeneous aerosol field with large spatial and temporal variability and reduction in uncertainties in aerosol quantification is a challenging task in atmospheric sciences. Keeping this in view the present study aims to assess the impact of aerosols on coastal Indian station Visakhapatnam and the adjoining Bay of Bengal. An aerosol is a colloid of fine solid particles or liquid droplets, in air or another gas. Aerosols can be natural or not. Examples of natural aerosols are fog, forest exudates and geyser steam.
Author: Ian Colbeck Publisher: John Wiley & Sons ISBN: 1119977924 Category : Science Languages : en Pages : 522
Book Description
AEROSOL SCIENCE TECHNOLOGY AND APPLICATIONS Aerosols influence many areas of our daily life. They are at the core of environmental problems such as global warming, photochemical smog and poor air quality. They can also have diverse effects on human health, where exposure occurs in both outdoor and indoor environments. However, aerosols can have beneficial effects too; the delivery of drugs to the lungs, the delivery of fuels for combustion and the production of nanomaterials all rely on aerosols. Advances in particle measurement technologies have made it possible to take advantage of rapid changes in both particle size and concentration. Likewise, aerosols can now be produced in a controlled fashion. Reviewing many technological applications together with the current scientific status of aerosol modelling and measurements, this book includes: Satellite aerosol remote sensing The effects of aerosols on climate change Air pollution and health Pharmaceutical aerosols and pulmonary drug delivery Bioaerosols and hospital infections Particle emissions from vehicles The safety of emerging nanomaterials Radioactive aerosols: tracers of atmospheric processes With the importance of this topic brought to the public's attention after the eruption of the Icelandic volcano Eyjafjallajökull, this book provides a timely, concise and accessible overview of the many facets of aerosol science.
Author: Shelley D. Minteer Publisher: Springer Science & Business Media ISBN: 1592599974 Category : Science Languages : en Pages : 245
Book Description
Hands-on researchers review the principles behind successful miniaturization and describe the key techniques for miniaturizing large-scale biochemical and bioanalytical methods for microchip analysis. The authors cover not only the most popular methods for the fabrication of microchips (photolithography, laser ablation, and soft lithography), but also microfluidic techniques for such bioanalytical assays and bioprocesses as DNA analysis, PCR, immunoassays, and cell reactors. Highlights include PCR on a microchip, microscale cell culturing, and the study of cellular processes on a microchip. The protocols offer step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
Author: Fobang Liu
Author: Fobang Liu
Author: National Research Council
Author: OECD
Author: Constantin Papastefanou
Author: Rekha Kale
Author: 
Author: United States. Department of Energy. Environmental Impacts Division
Author: Ian Colbeck
Author: Shelley D. Minteer
Author: