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Systems Biology in Toxicology and Environmental Health

Systems Biology in Toxicology and Environmental Health PDF Author: Rebecca Fry
Publisher: Academic Press
ISBN: 0128015683
Category : Medical
Languages : en
Pages : 285

Book Description
Systems Biology in Toxicology and Environmental Health uses a systems biological perspective to detail the most recent findings that link environmental exposures to human disease, providing an overview of molecular pathways that are essential for cellular survival after exposure to environmental toxicants, recent findings on gene-environment interactions influencing environmental agent-induced diseases, and the development of computational methods to predict susceptibility to environmental agents. Introductory chapters on molecular and cellular biology, toxicology and computational biology are included as well as an assessment of systems-based tools used to evaluate environmental health risks. Further topics include research on environmental toxicants relevant to human health and disease, various high-throughput technologies and computational methods, along with descriptions of the biological pathways associated with disease and the developmental origins of disease as they relate to environmental contaminants. Systems Biology in Toxicology and Environmental Health is an essential reference for undergraduate students, graduate students, and researchers looking for an introduction in the use of systems biology approaches to assess environmental exposures and their impacts on human health. - Provides the first reference of its kind, demonstrating the application of systems biology in environmental health and toxicology - Includes introductions to the diverse fields of molecular and cellular biology, toxicology, and computational biology - Presents a foundation that helps users understand the connections between the environment and health effects, and the biological mechanisms that link them

Systems Biology in Toxicology and Environmental Health

Systems Biology in Toxicology and Environmental Health PDF Author: Rebecca Fry
Publisher: Academic Press
ISBN: 0128015683
Category : Medical
Languages : en
Pages : 285

Book Description
Systems Biology in Toxicology and Environmental Health uses a systems biological perspective to detail the most recent findings that link environmental exposures to human disease, providing an overview of molecular pathways that are essential for cellular survival after exposure to environmental toxicants, recent findings on gene-environment interactions influencing environmental agent-induced diseases, and the development of computational methods to predict susceptibility to environmental agents. Introductory chapters on molecular and cellular biology, toxicology and computational biology are included as well as an assessment of systems-based tools used to evaluate environmental health risks. Further topics include research on environmental toxicants relevant to human health and disease, various high-throughput technologies and computational methods, along with descriptions of the biological pathways associated with disease and the developmental origins of disease as they relate to environmental contaminants. Systems Biology in Toxicology and Environmental Health is an essential reference for undergraduate students, graduate students, and researchers looking for an introduction in the use of systems biology approaches to assess environmental exposures and their impacts on human health. - Provides the first reference of its kind, demonstrating the application of systems biology in environmental health and toxicology - Includes introductions to the diverse fields of molecular and cellular biology, toxicology, and computational biology - Presents a foundation that helps users understand the connections between the environment and health effects, and the biological mechanisms that link them

Strategies to Protect the Health of Deployed U.S. Forces

Strategies to Protect the Health of Deployed U.S. Forces PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309068754
Category : Medical
Languages : en
Pages : 273

Book Description
Since Operation Desert Shield/Desert Storm, Gulf War veterans have expressed concerns about health effects that could be associated with their deployment and service during the war. Although similar concerns were raised after other military operations, the Gulf War deployment focused national attention on the potential, but uncertain, relationship between the presence of chemical and biological (CB) agents and other harmful agents in theater and health symptoms reported by military personnel. Strategies to Protect the Health of Deployed U.S. Forces which is one of the four two-year studies, examines the detection and tracking of exposures of deployed personnel to multiple harmful agents.

Biological Safety

Biological Safety PDF Author: Dawn P. Wooley
Publisher: John Wiley & Sons
ISBN: 155581963X
Category : Science
Languages : en
Pages : 300

Book Description
Biological safety and biosecurity protocols are essential to the reputation and responsibility of every scientific institution, whether research, academic, or production. Every risk—no matter how small—must be considered, assessed, and properly mitigated. If the science isn't safe, it isn't good. Now in its fifth edition, Biological safety: Principles and Practices remains the most comprehensive biosafety reference. Led by editors Karen Byers and Dawn Wooley, a team of expert contributors have outlined the technical nuts and bolts of biosafety and biosecurity within these pages. This book presents the guiding principles of laboratory safety, including: the identification, assessment, and control of the broad variety of risks encountered in the lab; the production facility; and, the classroom. Specifically, Biological Safety covers protection and control elements—from biosafety level cabinets and personal protection systems to strategies and decontamination methods administrative concerns in biorisk management, including regulations, guidelines, and compliance various aspects of risk assessment covering bacterial pathogens, viral agents, mycotic agents, protozoa and helminths, gene transfer vectors, zooonotic agents, allergens, toxins, and molecular agents as well as decontamination, aerobiology, occupational medicine, and training A resource for biosafety professionals, instructors, and those who work with pathogenic agents in any capacity, Biological safety is also a critical reference for laboratory managers, and those responsible for managing biohazards in a range of settings, including basic and agricultural research, clinical laboratories, the vivarium, field study, insectories, and greenhouses.

Monitoring Human Tissues for Toxic Substances

Monitoring Human Tissues for Toxic Substances PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309044375
Category : Science
Languages : en
Pages : 224

Book Description
The National Human Monitoring Program (NHMP) identifies concentrations of specific chemicals in human tissues, including toxicologic testing and risk assessment determinations. This volume evaluates the current activities of the NHMP; identifies important scientific, technical, and programmatic issues; and makes recommendations regarding the design of the program and use of its products.

How Tobacco Smoke Causes Disease

How Tobacco Smoke Causes Disease PDF Author: United States. Public Health Service. Office of the Surgeon General
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 728

Book Description
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

U.S. Health in International Perspective

U.S. Health in International Perspective PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309264146
Category : Social Science
Languages : en
Pages : 421

Book Description
The United States is among the wealthiest nations in the world, but it is far from the healthiest. Although life expectancy and survival rates in the United States have improved dramatically over the past century, Americans live shorter lives and experience more injuries and illnesses than people in other high-income countries. The U.S. health disadvantage cannot be attributed solely to the adverse health status of racial or ethnic minorities or poor people: even highly advantaged Americans are in worse health than their counterparts in other, "peer" countries. In light of the new and growing evidence about the U.S. health disadvantage, the National Institutes of Health asked the National Research Council (NRC) and the Institute of Medicine (IOM) to convene a panel of experts to study the issue. The Panel on Understanding Cross-National Health Differences Among High-Income Countries examined whether the U.S. health disadvantage exists across the life span, considered potential explanations, and assessed the larger implications of the findings. U.S. Health in International Perspective presents detailed evidence on the issue, explores the possible explanations for the shorter and less healthy lives of Americans than those of people in comparable countries, and recommends actions by both government and nongovernment agencies and organizations to address the U.S. health disadvantage.

Environmental Toxicology

Environmental Toxicology PDF Author: Ming-Ho Yu
Publisher: CRC Press
ISBN: 0203495462
Category : Science
Languages : en
Pages : 367

Book Description
An Indispensable Reference of Air, Soil, and Water Pollutants This second edition of Environmental Toxicology focuses on the biological and health effects toxins have on living organisms. It also stresses the relationship between human activity and the environment, relating changes in the environment with the changing patterns of human d

Toxicological Profile for Lead

Toxicological Profile for Lead PDF Author:
Publisher:
ISBN:
Category : Lead
Languages : en
Pages : 584

Book Description


Handbook of Hazardous Materials

Handbook of Hazardous Materials PDF Author:
Publisher: Academic Press
ISBN: 0323139558
Category : Medical
Languages : en
Pages : 791

Book Description
Handbook of Hazardous Materials is a one-volume compendium of hazardous materials that discusses the toxic effects of these materials on human health and the global environment. It provides comprehensive coverage of individual toxic elements, covers hazardous material groups, and includes more general articles such as evaluation and testing of carcinogens, transport of pollutants, and inhalation toxicology. The fully referenced articles are presented in alphabetical order. The book features a subject index as well as numerous cross-references.Individual articles are preceded by a topical outline and discuss the origin, prevalence, mechanisms of toxicity and damaging effects of each hazardous material.Comprehensive coverage of individual toxic elements, includingAsbestosAlarLeadMercuryCoverage of hazardous material groups, such asPesticidesFood additivesNitrogen compoundsMore general articles, such asEvaluation and testing of carcinogensTransport of pollutantsInhalation toxicology

Toxicological Profile for Toluene

Toxicological Profile for Toluene PDF Author:
Publisher:
ISBN:
Category : Toluene
Languages : en
Pages : 366

Book Description