Author: Tarun Belwal Publisher: Academic Press ISBN: 0128192135 Category : Medical Languages : en Pages : 534
Book Description
Naturally Occurring Chemicals against Alzheimer's Disease offers a detailed discussion on the roles, molecular mechanisms, structural activity relationships, toxicology and clinical data on phytochemicals in relation to Alzheimer's disease. The book examines the available phytochemicals and plants that are potentially effective, also determining the role and molecular targets of these phytochemicals in combating AD. This comprehensive resource will be helpful to researchers who are working on herbal drugs on AD, phytochemistry, pharmacology, toxicology, clinical trials, neuroscience and advancement in formulations. - Provides information on phytochemistry, pharmacology, toxicology, clinical trials, and advancement in formulations specific to Alzheimer's Disease in a single source - Explores natural compounds, which can be more affordable to the majority of Alzheimer's Disease patients, who will increasingly be in developing countries - Covers a wide array of specific chemical compounds
Author: Goutam Brahmachari Publisher: Elsevier ISBN: 0128097698 Category : Science Languages : en Pages : 492
Book Description
Discovery and Development of Neuroprotective Agents from Natural Products draws together global research on medicinal agents from natural sources as starting points for the design of neuroprotective drugs. From the prediction of promising leads and identification of active agents to the extraction of complex molecules, the book explores a range of important topics to support the development of safer, more economical therapeutics for these increasingly prevalent diseases. Beginning with an overview of current developments in the field, the book goes on to explore the identification, extraction and phytochemistry of such neuroprotective agents as antioxidants, biophenols and naturally occurring anti-inflammatory steroid analogues. Specific natural sources of bioactive agents are reviewed, and the development of these agents into therapeutics for a number of specific neurological disorders, including Alzheimer's disease, Parkinson's disease and ischemic brain stroke, are discussed. Combining the expertise of specialists from around the world, this in the Natural Products Drug Discovery series aims to support and encourage researchers in the investigation of natural sources as starting points for the development of standardized, safe and effective neuroprotective drugs. - Features chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery - Includes comprehensive coverage of cutting-edge research advances in the design of drugs from natural products targeted at different kinds of neurodegenerative diseases - Offers a practical review of identification, isolation and extraction techniques to support medicinal chemists in the lab
Author: Publisher: Academic Press ISBN: 012811780X Category : Medical Languages : en Pages : 332
Book Description
Neurobiology of Chinese Herb Medicine, Volume 135 is a valuable book for anyone interested in alternative medicine or the scientific research surrounding ancient herbal medicine. This updated volume in the series includes chapters that delve into timely topics, including the Effects of Lycium Barbarum on the Visual System, the Effect of Chinese Herbal Medicine on Alzheimer's Disease, the Effect and Mechanism of Chinese Herbal Medicine on Parkinson's Disease, the Neurobiology of Chinese Herbal Medicine on Major Depressive Disorder, the Treatment of Insomnia with Traditional Chinese Herbal Medicine, and the Metabolic Factors and Adult Neurogenesis: Impacts of Chinese Herbal Medicine on Brain Repair in Neurological Diseases. This series is ideal for Chinese herbal medicine practitioners who are working in a clinical environment, although the clinical applications of Chinese medicinal herbs presented provide useful references and guidance for any clinical practice that specializes in the treatment of various conditions. - Presents a wealth of information on the use of Chinese herbal medicine and its application to many conditions - Provides basic research and clinical studies of Chinese herbal medicines, either as compounds/extracts or formulas - Sheds light on possible action mechanisms of many Chinese herbal medicines
Author: Sudhir P. Singh Publisher: Elsevier ISBN: 044464086X Category : Technology & Engineering Languages : en Pages : 444
Book Description
Current Developments in Biotechnology and Bioengineering: Synthetic Biology, Cell Engineering and Bioprocessing Technologies covers the current perspectives and outlook of synthetic biology in the agriculture, food and health sectors. This book begins with the basics about synthetic biology and cell engineering, and then explores this in more detail, focusing on topics like applications of synthetic biology, industrial bioprocesses, and future perspectives. Information on cell engineering is also presented, and manipulation in endogenous metabolic network is studied alongside advanced topics such as fine tuning of metabolic pathways, de novo biosynthetic pathway design, enzyme engineering targeted to improved kinetics and stability, and potential applications of the novel biological systems in bioprocess technology to achieve the production of value-added compounds with specific biological activities. - Assists in developing a conceptual understanding of synthetic biology and cellular and metabolic engineering. - Includes comprehensive information on new developments and advancements. - Lists applications of synthetic biology in agriculture, food, and health
Author: Atta-ur Rahman Publisher: Elsevier ISBN: 0128039620 Category : Science Languages : en Pages : 487
Book Description
Originally published by Bentham and now distributed by Elsevier, Recent Advances in Medicinal Chemistry, Volume 1 covers leading-edge research and recent developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies. The fourteen updated reviews include unique experimental data and references, and each article highlights an important topic in current medicinal chemistry research. Topics covered include: aureolic acid group of anti-cancer antibiotics and non-steroidal anti-inflammatory drugs; aromatase inhibitors in adjuvant endocrine treatment of early-stage breast cancer in postmenopausal women; Rho GTPases and statins in targeting and developing therapies for tumors; and more. - Edited and written by leading experts in medicinal chemistry research - Reviews recent advances in the field, including the characterization of inorganic nanomaterials as therapeutic vehicles - Covers a variety of topical areas, such as HPLC and in the analysis of tricyclic antidepressants in biological samples, and tannins and their influence on health
Author: Goutam Brahmachari Publisher: Elsevier ISBN: 0128157240 Category : Science Languages : en Pages : 461
Book Description
Discovery and Development of Therapeutics from Natural Products against Neglected Tropical Diseases draws together research on medicinal agents from natural sources as starting points for the design of drugs against Neglected Tropical Diseases (NTDs). From the prediction of promising leads and identification of active agents, to the extraction of complex molecules, the book explores novel, economical and efficacious therapeutics for these diseases. It describes current research and the role of natural products, antimalarial compounds from marine natural products and sesquiterpene lactones, natural antileprotic agents, natural products with potential against Leishmaniasis, Trypanosomiasis and Dengue, and more. In addition, Quinoline and Isoquinoline alkaloids for developing new antiprotozoal agents are discussed, alongside anti-trypanosomatid heterocyclic compounds as structures for development. Combining the expertise of specialists from around the world, this volume aims to support and encourage researchers in the investigation of natural sources as starting points for the development of novel, safe and effective agents for use against neglected tropical diseases. - Includes chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery - Draws together cutting-edge research advances in natural product chemistry that are targeted at neglected tropical diseases - Highlights the future potential of natural products as sources of novel medicinal compounds against neglected tropical diseases
Author: Christophe Wiart Publisher: Academic Press ISBN: 0123983835 Category : Medical Languages : en Pages : 415
Book Description
Lead Compounds from Medicinal Plants for the Treatment of Neurodegenerative Diseases is the second volume in the series, Pharmaceutical Leads from Medicinal Plants. This book includes key pharmacological and chemical evidence to support the selection of promising pre-clinical candidates for the treatment of neurodegenerative diseases. This important addition to the natural product and drug discovery literature contains the history, synonyms, medicinal uses, phytopharmacology, pre-clinical potential, and rationale for each plant selected. By providing critical evaluation of pharmacological data, mechanisms of action, and structural requirements for the development of future neuroprotective agents, this comprehensive reference is a beneficial resource for industry and academic scientists whose research focuses on neurodegenerative drug discovery and development. - Incorporates compelling biological activity data and preclinical structure-activity relationships to help you choose promising lead molecules for further research - Includes primary source references to the most recent natural product discoveries in the field of neuroprotection in order to promote new drug discovery in this area - Contains detailed discussions of important neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease - Each plant section includes a critical evaluation of pharmacological, chemical, and toxicological evidence to support the use of the compound in drug discovery research in neurodegeneration
Author: Tarun Belwal
Author: Goutam Brahmachari
Author: S. William Pelletier
Author: 
Author: Sudhir P. Singh
Author: Atta-ur Rahman
Author: Goutam Brahmachari
Author: Christophe Wiart
Author: Weiwei Zhang
Author: Christophe Wiart