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Author: Jill Charles Publisher: CRC Press ISBN: 1351767720 Category : Medical Languages : en Pages : 99
Book Description
Cancer threatens the lives of people around the world. Women, in particular, are at risk of certain cancers with a genetic cause. Certain mutations in the BRCA1 and BRCA2 genes put mothers and daughters at risk of breast and ovarian cancers. Unlike many cancers that most commonly occur after age 60, these inheritable cancers threaten women’s lives, health and fertility even when they are young, before most would even begin to go for annual mammogram screenings to check for breast cancer. Three Daughters, Three Journeys takes on the biggest health issue of our time from a global perspective with three heroines fighting for their lives against cancer. Marzena, a Polish oncology nurse, has spent her life treating child patients with cancer. Then, she confronts it in her own family and her own body. Kamola, a rural Indian girl, knows she has symptoms of the same disease that took her mother, but feels afraid to discuss it with her father and brothers, knowing her family cannot afford medical treatment. Kamola confides in Dr Rini Mishra, a doctor testing a new treatment called Neelazin, using a bacterial anticancer protein in food, to destroy cancer cells. Selena, a wealthy woman of color in Chicago, finds out about her genetic risks of breast and ovarian cancer. She has a choice of preventative surgery that will save her life but remove any chance of having children. As she meets women who struggle to afford cancer treatment, Selena dedicates her life to providing affordable homes and counseling to families affected by the disease. Although the drug Neelazin is fictional, the possibility of new cancer treatments using bacterial anticancer proteins is being researched now. A problem with the current chemotherapy for cancer treatment is the high toxicity of most of these drugs, as these drugs can enter both normal and cancer cells, though preferably cancer cells, causing the death of normal cells as well that are important in maintaining health. Another problem is that current chemotherapeutic drugs mostly target a single or few key steps that are important for cancer growth and proliferation and inhibit the growth of cancer cells. The cancer cells respond by quickly changing these single targets, thereby becoming resistant to the drugs, as is reflected in stage IV cancer patients. An alternative to chemotherapy would be to exploit the bacterial evolutionary wisdom and use certain proteins that can have preferential entry to cancer cells in order to minimize normal cell toxicity and multiple targets in cancer cells through protein–protein complex formation, thus reducing resistance development in cancer cells. An interesting advantage of protein drugs is to express them as part of food, and some recent research seems to suggest that oral consumption of such foods may allow the therapeutic protein to reach the blood stream to target the cancer. Women with the genetic risk factors could soon have the choice of taking a pill or such anticancer protein-expressing food to treat or prevent cancer, rather than removing the healthy tissue of the breasts and ovaries. Hopefully, they would not have to choose between fertility and survival, as is the implied message in this book, fictional as it is at this time.
Author: Jill Charles Publisher: CRC Press ISBN: 1351767720 Category : Medical Languages : en Pages : 99
Book Description
Cancer threatens the lives of people around the world. Women, in particular, are at risk of certain cancers with a genetic cause. Certain mutations in the BRCA1 and BRCA2 genes put mothers and daughters at risk of breast and ovarian cancers. Unlike many cancers that most commonly occur after age 60, these inheritable cancers threaten women’s lives, health and fertility even when they are young, before most would even begin to go for annual mammogram screenings to check for breast cancer. Three Daughters, Three Journeys takes on the biggest health issue of our time from a global perspective with three heroines fighting for their lives against cancer. Marzena, a Polish oncology nurse, has spent her life treating child patients with cancer. Then, she confronts it in her own family and her own body. Kamola, a rural Indian girl, knows she has symptoms of the same disease that took her mother, but feels afraid to discuss it with her father and brothers, knowing her family cannot afford medical treatment. Kamola confides in Dr Rini Mishra, a doctor testing a new treatment called Neelazin, using a bacterial anticancer protein in food, to destroy cancer cells. Selena, a wealthy woman of color in Chicago, finds out about her genetic risks of breast and ovarian cancer. She has a choice of preventative surgery that will save her life but remove any chance of having children. As she meets women who struggle to afford cancer treatment, Selena dedicates her life to providing affordable homes and counseling to families affected by the disease. Although the drug Neelazin is fictional, the possibility of new cancer treatments using bacterial anticancer proteins is being researched now. A problem with the current chemotherapy for cancer treatment is the high toxicity of most of these drugs, as these drugs can enter both normal and cancer cells, though preferably cancer cells, causing the death of normal cells as well that are important in maintaining health. Another problem is that current chemotherapeutic drugs mostly target a single or few key steps that are important for cancer growth and proliferation and inhibit the growth of cancer cells. The cancer cells respond by quickly changing these single targets, thereby becoming resistant to the drugs, as is reflected in stage IV cancer patients. An alternative to chemotherapy would be to exploit the bacterial evolutionary wisdom and use certain proteins that can have preferential entry to cancer cells in order to minimize normal cell toxicity and multiple targets in cancer cells through protein–protein complex formation, thus reducing resistance development in cancer cells. An interesting advantage of protein drugs is to express them as part of food, and some recent research seems to suggest that oral consumption of such foods may allow the therapeutic protein to reach the blood stream to target the cancer. Women with the genetic risk factors could soon have the choice of taking a pill or such anticancer protein-expressing food to treat or prevent cancer, rather than removing the healthy tissue of the breasts and ovaries. Hopefully, they would not have to choose between fertility and survival, as is the implied message in this book, fictional as it is at this time.
Author: Consuelo Saah Baehr Publisher: Lake Union Press ISBN: 9781477826195 Category : Fiction Languages : en Pages : 720
Book Description
From the fertile hills of a tiny village near Jerusalem to the elegant townhouses of Georgetown, Three Daughters is a historical saga that chronicles the lives, loves, and secrets of three generations of Palestinian Christian women. Born in rural Palestine, just before the dawn of the twentieth century, Miriam adores her father and is certain his love will protect her, but she soon finds that tradition overrides love. Uprooted by war, Miriam enters a world where the old constraints slip away with thrilling and disastrous results. Miriam's rebellious daughter, Nadia, is thrilled with the opportunity for a modern life that her elite education provides. But when she falls in love with an outsider, the clan reins her back with a shocking finality. Nijmeh, Nadia's daughter, is an only child and the path her father, the sheik, sets for her is fraught with difficulties, yet it prepares her for her ultimate journey to America, where she finds her future. Each woman, in her own time and in her own way, experiences a world in transition through war and social change...and each must stretch the bounds of her loyalty, her courage, and her heart.
Author: Lena Nelson Dooley Publisher: ISBN: 9781963212150 Category : Fiction Languages : en Pages : 0
Book Description
A secret adoption, a quest for identity, and a love that could change her life forever. Margaret Lenora Caine has never fit the mold her mother set for her. When Maggie discovers proof she was adopted, the rift between them only tears deeper. Feeling the sting of betrayal, Maggie requests permission to visit her grandmother in Little Rock, Arkansas. There she'll set her sights on her dream of becoming a successful dress designer and maybe find her true identity in the process. Her father's one condition is that she must be travel with her young aunt and her father's handsome business partner, Charles Stanton-the man who once held her affections. Charles Stanton, a thriving businessman, has taken a calculated risk by joining forces with Maggie's father in a joint venture. When asked to chaperone his new partner's sister-in-law and daughter on a cross-country trip, Charles sees it as an opportunity to strengthen their business ties. Though he initially sets his sights on Maggie's charming and composed aunt as a potential wife, Charles soon finds himself increasingly captivated by Maggie's resilience and charm. With each passing mile, the bond between Maggie and Charles deepens, challenging both Maggie's plans and her heart. Will the love growing between them help her embrace her identity-or complicate her search for what truly matters in life?
Author: Jung Chang Publisher: Simon and Schuster ISBN: 1439106495 Category : Biography & Autobiography Languages : en Pages : 592
Book Description
The story of three generations in twentieth-century China that blends the intimacy of memoir and the panoramic sweep of eyewitness history—a bestselling classic in thirty languages with more than ten million copies sold around the world, now with a new introduction from the author. An engrossing record of Mao’s impact on China, an unusual window on the female experience in the modern world, and an inspiring tale of courage and love, Jung Chang describes the extraordinary lives and experiences of her family members: her grandmother, a warlord’s concubine; her mother’s struggles as a young idealistic Communist; and her parents’ experience as members of the Communist elite and their ordeal during the Cultural Revolution. Chang was a Red Guard briefly at the age of fourteen, then worked as a peasant, a “barefoot doctor,” a steelworker, and an electrician. As the story of each generation unfolds, Chang captures in gripping, moving—and ultimately uplifting—detail the cycles of violent drama visited on her own family and millions of others caught in the whirlwind of history.
Author: Elif Shafak Publisher: Bloomsbury Publishing USA ISBN: 1632869977 Category : Fiction Languages : en Pages : 385
Book Description
An Indie Next Pick The stunning, timely new novel from the acclaimed, internationally bestselling author of The Architect's Apprentice and The Bastard of Istanbul. Peri, a married, wealthy, beautiful Turkish woman, is on her way to a dinner party at a seaside mansion in Istanbul when a beggar snatches her handbag. As she wrestles to get it back, a photograph falls to the ground--an old polaroid of three young women and their university professor. A relic from a past--and a love--Peri had tried desperately to forget. Three Daughters of Eve is set over an evening in contemporary Istanbul, as Peri arrives at the party and navigates the tensions that simmer in this crossroads country between East and West, religious and secular, rich and poor. Over the course of the dinner, and amidst an opulence that is surely ill-begotten, terrorist attacks occur across the city. Competing in Peri's mind however are the memories invoked by her almost-lost polaroid, of the time years earlier when she was sent abroad for the first time, to attend Oxford University. As a young woman there, she had become friends with the charming, adventurous Shirin, a fully assimilated Iranian girl, and Mona, a devout Egyptian-American. Their arguments about Islam and feminism find focus in the charismatic but controversial Professor Azur, who teaches divinity, but in unorthodox ways. As the terrorist attacks come ever closer, Peri is moved to recall the scandal that tore them all apart. Elif Shafak is the number one bestselling novelist in her native Turkey, and her work is translated and celebrated around the world. In Three Daughters of Eve, she has given us a rich and moving story that humanizes and personalizes one of the most profound sea changes of the modern world.
Author: Janice P. Nimura Publisher: W. W. Norton & Company ISBN: 0393248240 Category : History Languages : en Pages : 306
Book Description
A Seattle Times Best Book of the Year A Buzzfeed Best Nonfiction Book of the Year "Nimura paints history in cinematic strokes and brings a forgotten story to vivid, unforgettable life." —Arthur Golden, author of Memoirs of a Geisha In 1871, five young girls were sent by the Japanese government to the United States. Their mission: learn Western ways and return to help nurture a new generation of enlightened men to lead Japan. Raised in traditional samurai households during the turmoil of civil war, three of these unusual ambassadors—Sutematsu Yamakawa, Shige Nagai, and Ume Tsuda—grew up as typical American schoolgirls. Upon their arrival in San Francisco they became celebrities, their travels and traditional clothing exclaimed over by newspapers across the nation. As they learned English and Western customs, their American friends grew to love them for their high spirits and intellectual brilliance. The passionate relationships they formed reveal an intimate world of cross-cultural fascination and connection. Ten years later, they returned to Japan—a land grown foreign to them—determined to revolutionize women’s education. Based on in-depth archival research in Japan and in the United States, including decades of letters from between the three women and their American host families, Daughters of the Samurai is beautifully, cinematically written, a fascinating lens through which to view an extraordinary historical moment.
Author: Nick (Yu) He Publisher: ISBN: 9781733969505 Category : Travel Languages : en Pages : 292
Book Description
One hundred percent made in China, Nick (Yu) grew up in an environment where being gay was not an option. The expectation from his parents and pressure from the society molded him into the "best student" and "best employee." He made his family proud. But deep inside, he knew that something was missing, and he was different. In this memoir, Nick (Yu) takes readers on his journey from growing up as a confused "straight" boy from China to today having a lovely husband and three girls through surrogacy. He invites readers to the experiences that he would rather have forgotten - from being sexually harassed by his desk-mate in middle school, through depression and a one-night stand in college, to losing a baby during pregnancy. With ultimate honesty and absolute vulnerability, Nick shares the happiness and sadness on the journey to come out to himself, his parents and friends; learn about gay culture in America, cherish his Chinese heritage, find his first love, and create a family through surrogacy and the help of many amazing people. Two Dads and Three Girls is a celebration of courage and love. It challenges each of us to dig deep into our soul to find what matters most to us, gain courage through the stories, and live our lives in truth.
Author: Heather Morris Publisher: Bonnier Zaffre Ltd. ISBN: 1838774580 Category : Fiction Languages : en Pages : 381
Book Description
'Gripping, heartbreaking and uplifting.' Christy Lefteri, author of the million-copy bestseller The Beekeeper of Aleppo THEIR STORY WILL BREAK YOUR HEART THEIR JOURNEY WILL FILL YOU WITH HOPE YOU WILL NEVER FORGET THEIR NAMES When they are little girls, Cibi, Magda and Livia make a promise to their father - that they will stay together, no matter what. Years later, at just 15, Livia is ordered to Auschwitz by the Nazis. Cibi, only 19 herself, remembers their promise and follows Livia, determined to protect her sister, or die with her. Together, they fight to survive through unimaginable cruelty and hardship. Magda, only 17, stays with her mother and grandfather, hiding out in a neighbour's attic or in the forest when the Nazi militia come to round up friends, neighbours and family. She escapes for a time, but eventually she too is captured and transported to the death camp. In Auschwitz-Birkenau the three sisters are reunited and, remembering their father, they make a new promise, this time to each other: That they will survive. Three Sisters is a beautiful story of hope in the hardest of times and of finding love after loss. Heather Morris is the global bestselling author of The Tattooist of Auschwitz and Cilka's Journey, which have sold eight million copies worldwide. Three Sisters is her third novel, and the final piece in the phenomenon that is the Tattooist of Auschwitz series. The Tattooist of Auschwitz is a #3 Sunday Times bestseller from 5 May 2024
Author: Jill Charles
Author: Jill Charles
Author: Consuelo Saah Baehr
Author: Catherine Kerrison
Author: Lena Nelson Dooley
Author: Jung Chang
Author: Elif Shafak
Author: Janice P. Nimura
Author: Consuelo Saah Baehr
Author: Nick (Yu) He
Author: Heather Morris