Therapeutic Drug Monitoring and Toxicology by Liquid Chromatography PDF Download

Author: Steven H.Y. Wong
Publisher: Routledge
ISBN: 1351408461
Category : Medical
Languages : en
Pages : 673

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Book Description
First Published in 2017. Routledge is an imprint of Taylor & Francis, an Informa company.

Author: Q. Alan Xu
Publisher: John Wiley & Sons
ISBN: 0470922796
Category : Science
Languages : en
Pages : 913

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Book Description
This book is a compilation of summarized analytical methods designed to serve the needs of pharmacologists, toxicologists, and other allied health professionals involved the development, use, or monitoring of pharmaceuticals. The summaries are structured monographs on 511 different drug entities detailing 964 different analytical methods, providing the reader with a thorough description of method validation. These analytical methods include not only high performance liquid chromatography (HPLC), but also gas chromatography (GC), immunoassay, electrophoresis, ultra performance liquid chromatography (UPLC) coupled with UV (UPLC-UV) detection and mass spectrometry (UPLC-MS/MS). With more detailed and complete summaries than sketchy and abbreviated formats used in the other books, this book provides a thorough description of method validation and results, as well as the operating parameters.

Author: Ed Wong SHY
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Author: Steven H.Y. Wong
Publisher: CRC Press
ISBN: 1351364278
Category : Medical
Languages : en
Pages : 570

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Book Description
Adapting modern advances in analytical techniques to daily laboratory practices challenges many toxicologists, clinical laboratories, and pharmaceutical scientists. The Handbook of Analytical Therapeutic Drug Monitoring and Toxicology helps you keep abreast of the innovative changes that can make your laboratory - and the studies undertaken in it - a success. This volume simplifies your search for appropriate techniques, describes recent contributions from leading investigators, and provides valuable evaluations and advice.

Author: Amitava Dasgupta
Publisher: CRC Press
ISBN: 1420067591
Category : Medical
Languages : en
Pages : 475

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Book Description
For drugs with a narrow therapeutic index, therapeutic drug monitoring methods are essential for patient management. Although immunoassays are commercially available for many drugs and most laboratories use these assays for routine therapeutic monitoring, they have many limitations which hinder their efficacy. Providing practical guidelines for imp

Author: Randall C. Baselt
Publisher: CRC Press
ISBN:
Category : Medical
Languages : en
Pages : 354

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Book Description
Procedures to determine overdosage or poisoning include: colorimetry, visible and ultraviolet spectrophotometry, mass and atomic absorption spectrometry, flame photometry, ion-specific potentiometry, graphite furnace atomic absorption, liquid chromatography and thin layer chromatography. Gas chromatography procedures include flame ionization, electron capture, nitrogen specific, and thermal conductivity.

Author: Irving Sunshine
Publisher: CRC Press
ISBN: 1000943038
Category : Medical
Languages : en
Pages : 807

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Book Description
Papers from the Second International Conference on TDM Toxicology (date and place not stated) describe research on various aspects of therapeutic monitoring pharmacology, selected high-performance liquid chromatographic methods, antiepileptics, substances subject to abuse, inorganics. Over 100 contr

Author: Seth Kwabena Amponsah
Publisher: Springer Nature
ISBN: 3031123980
Category : Medical
Languages : en
Pages : 384

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Book Description
This book gives an overview of therapeutic drug monitoring (TDM) and its clinical application. It also highlights recent advances in toxicological studies, as they relate to therapeutic drug monitoring. This is one of the few books available on the market that covers TDM. Therapeutic drug monitoring (TDM) is a clinical decision-making tool that enables dosage regimen adjustments based on clinical and laboratory measurements. TDM not only involves the measuring of drug concentrations but also interpretation of the results. There is a strong correlation between drug concentrations in body fluids and outcome than between dose and outcome. The chapters include coverage of analytical techniques, pharmacokinetics, therapeutic indices, artificial intelligence and recent advances in toxicological studies. The book fills a gap in published literature and provides reliable information on; Analytical techniques in TDM and clinical toxicology TDM and pharmacokinetic studies TDM of drugs with narrow therapeutic indices Artificial intelligence in TDM and clinical toxicology Future directions and challenges

Author: Amitava Dasgupta
Publisher: Springer Science & Business Media
ISBN: 1597450316
Category : Medical
Languages : en
Pages : 441

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Book Description
Written in a handbook style with specific methods and tips on eliminating false positive and false negative results, this book is a practical guide to the detailed mechanisms of such occurrences.

Author: Amitava Dasgupta
Publisher: Academic Press
ISBN: 0128158506
Category : Science
Languages : en
Pages : 382

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Book Description
Therapeutic Drug Monitoring Data: A Concise Guide, Fourth Edition serves as a ready resource of information on commonly monitored drugs that will help readers make decisions relating to the monitoring and interpretation of results. It is an easy-to-read source of information on intended use, pharmacokinetics, therapeutic range, and toxic concentrations, as well as bioavailability, disposition, metabolism and the excretion of commonly monitored therapeutic drugs. This fully updated fourth edition includes sections on new anticonvulsants, anti-depressant and anti-HIV drugs, new drugs for advanced cancer treatment, and thoroughly updated chapters that address new pitfalls and problems in the lab. Serves as a ready resource of information for commonly monitored drugs Presents a useful, quick guide for those making decisions related to monitoring and interpretation of results Provides concise, easily digestible content for clinical laboratory scientists, toxicologists and clinicians