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The use of rectal artesunate as a pre-referral treatment for severe P. falciparum malaria

The use of rectal artesunate as a pre-referral treatment for severe P. falciparum malaria PDF Author:
Publisher: World Health Organization
ISBN: 9240042512
Category : Medical
Languages : en
Pages : 3

Book Description
The WHO Malaria Policy Advisory Group (MPAG) recently reviewed the evidence from a large-scale study in 3 African countries deploying rectal artesunate under real-life conditions. This information note shares the findings of the study and possible implications for the use of RAS as pre-referral treatment for severe malaria, and makes concrete recommendations for countries to consider. The WHO Global Malaria Programme, in consultation with other relevant departments, will conduct a formal evidence review and develop detailed guidance on the conditions under which the use of this tool can be implemented safely and effectively. Such guidance will be shared with countries as soon as it becomes available.

The use of rectal artesunate as a pre-referral treatment for severe P. falciparum malaria

The use of rectal artesunate as a pre-referral treatment for severe P. falciparum malaria PDF Author:
Publisher: World Health Organization
ISBN: 9240042512
Category : Medical
Languages : en
Pages : 3

Book Description
The WHO Malaria Policy Advisory Group (MPAG) recently reviewed the evidence from a large-scale study in 3 African countries deploying rectal artesunate under real-life conditions. This information note shares the findings of the study and possible implications for the use of RAS as pre-referral treatment for severe malaria, and makes concrete recommendations for countries to consider. The WHO Global Malaria Programme, in consultation with other relevant departments, will conduct a formal evidence review and develop detailed guidance on the conditions under which the use of this tool can be implemented safely and effectively. Such guidance will be shared with countries as soon as it becomes available.

Saving Lives, Buying Time

Saving Lives, Buying Time PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309165938
Category : Medical
Languages : en
Pages : 384

Book Description
For more than 50 years, low-cost antimalarial drugs silently saved millions of lives and cured billions of debilitating infections. Today, however, these drugs no longer work against the deadliest form of malaria that exists throughout the world. Malaria deaths in sub-Saharan Africaâ€"currently just over one million per yearâ€"are rising because of increased resistance to the old, inexpensive drugs. Although effective new drugs called "artemisinins" are available, they are unaffordable for the majority of the affected population, even at a cost of one dollar per course. Saving Lives, Buying Time: Economics of Malaria Drugs in an Age of Resistance examines the history of malaria treatments, provides an overview of the current drug crisis, and offers recommendations on maximizing access to and effectiveness of antimalarial drugs. The book finds that most people in endemic countries will not have access to currently effective combination treatments, which should include an artemisinin, without financing from the global community. Without funding for effective treatment, malaria mortality could double over the next 10 to 20 years and transmission will intensify.

Technical consultation to review the effectiveness of rectal artesunate used as pre-referral treatment of severe malaria in children

Technical consultation to review the effectiveness of rectal artesunate used as pre-referral treatment of severe malaria in children PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 924007421X
Category : Medical
Languages : en
Pages : 80

Book Description
This document is the report of a WHO technical consultation of independent experts convened in October 2022. The aim of the consultation was to conduct a formal evidence review of several studies evaluating the effectiveness of rectal artesunate (RAS) as a pre-referral treatment for severe malaria. In addition to the study published under the Community Access to Rectal Artesunate for Malaria Project, the review included other studies from early-use countries deploying RAS at the programmatic level. The main objective of the technical consultation was to support the development of guidance for the safe and effective implementation of this intervention based on the evidence from areas where RAS has already been implemented.

Guidelines for the Treatment of Malaria. Third Edition

Guidelines for the Treatment of Malaria. Third Edition PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241549122
Category : Medical
Languages : en
Pages : 317

Book Description
Malaria remains an important cause of illness and death in children and adults in countries in which it is endemic. Malaria control requires an integrated approach including prevention (primarily vector control) and prompt treatment with effective antimalarial agents. Malaria case management consisting of prompt diagnosis and effective treatment remains a vital component of malaria control and elimination strategies. Since the publication of the first edition of the Guidelines for the treatment of malaria in 2006 and the second edition in 2010 all countries in which P. falciparum malaria is endemic have progressively updated their treatment policy from use of ineffective monotherapy to the currently recommended artemisinin-based combination therapies (ACT). This has contributed substantially to current reductions in global morbidity and mortality from malaria. Unfortunately resistance to artemisinins has arisen recently in P. falciparum in South-East Asia which threatens these gains. This third edition of the WHO Guidelines for the treatment of malaria contains updated recommendations based on a firmer evidence base for most antimalarial drugs and in addition include recommendation on the use of drugs to prevent malaria in groups at high risk. The Guidelines provide a framework for designing specific detailed national treatment protocols taking into account local patterns of resistance to antimalarial drugs and health service capacity. It provides recommendations on treatment of uncomplicated and severe malaria in all age groups all endemic areas in special populations and several complex situations. In addition on the use of antimalarial drugs as preventive therapy in healthy people living in malaria-endemic areas who are high risk in order to reduce morbidity and mortality from malaria. The Guidelines are designed primarily for policy-makers in ministries of health who formulate country-specific treatment guidelines. Other groups that may find them useful include health professionals and public health and policy specialists that are partners in health or malaria control and the pharmaceutical industry. The treatment recommendations in the main document are brief; for those who wish to study the evidence base in more detail a series of annexes is provided with references to the appropriate sections of the main document.

Management of Severe Malaria

Management of Severe Malaria PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241545232
Category : Medical
Languages : en
Pages : 84

Book Description
Malaria continues to be a major health problem in many parts of the world, with over 2,400 million people in 100 countries at risk of infection. This handbook is an updated edition of 'Management of severe and complicated malaria', providing practical guidance on the diagnosis and management of severe falciparum malaria, a form of the disease that can have life-threatening complications if treatment is delayed.

Guidelines for the Treatment of Malaria

Guidelines for the Treatment of Malaria PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241547928
Category : Medical
Languages : en
Pages : 208

Book Description
"The purpose of this document is to provide comprehensible, global, evidence-based guidelines to help formulate policies and protocols for the treatment of malaria. Information is presented on the treatment of uncomplicated malaria, including disease in special groups (young children, pregnant women, people who are HIV positive, travellers from non-malaria endemic regions) and in complex emergency situations and severe malaria."--Publisher's description.

Principles of Medicine in Africa

Principles of Medicine in Africa PDF Author: David Mabey
Publisher: Cambridge University Press
ISBN: 1107002516
Category : Medical
Languages : en
Pages : 929

Book Description
The essential text for all healthcare professionals wanting a complete, up-to-date practical reference book on medicine in Africa.

Pocket Book of Hospital Care for Children

Pocket Book of Hospital Care for Children PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241548371
Category : Business & Economics
Languages : en
Pages : 442

Book Description
The Pocket Book is for use by doctors nurses and other health workers who are responsible for the care of young children at the first level referral hospitals. This second edition is based on evidence from several WHO updated and published clinical guidelines. It is for use in both inpatient and outpatient care in small hospitals with basic laboratory facilities and essential medicines. In some settings these guidelines can be used in any facilities where sick children are admitted for inpatient care. The Pocket Book is one of a series of documents and tools that support the Integrated Managem.

Disease Control Priorities, Third Edition (Volume 6)

Disease Control Priorities, Third Edition (Volume 6) PDF Author: King K. Holmes
Publisher: World Bank Publications
ISBN: 1464805253
Category : Medical
Languages : en
Pages : 1027

Book Description
Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Medical Pharmacology and Therapeutics E-Book

Medical Pharmacology and Therapeutics E-Book PDF Author: Derek G. Waller
Publisher: Elsevier Health Sciences
ISBN: 0702055034
Category : Medical
Languages : en
Pages : 741

Book Description
This book covers all the pharmacology you need, from basic science pharmacology and pathophysiology, through to clinical pharmacology to therapeutics, in line with the integrated approach of new medical curricula. The first section covers the basic principles, and the rest is organised by body systems. The book ends with sections on toxicity and prescribing practice. Integrates basic science pharmacology, clinical pharmacology and therapeutics Brief review of pathophysiology of major diseases Case histories and multiple choice questions (and answers) Tabular presentation of all common drugs within each class Section on further reading Kinetics chapter simplified with more practical examples Includes more on genetic issues Drug tables made more concise to make information more accessible Fully updated to reflect current clinical practice