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Author: Isadora De F√°tima Braga Magalh√£es Publisher: ISBN: Category : Electronic books Languages : en Pages : 0
Book Description
The importance of a new anticancer drug for breast cancer is well established. Natural compounds that can prevent this disease or be used as an adjuvant treatment associated with conventional drugs could be the solution for this. This chapter is an overview of agents extracted from plants with outstand results in the last six years. Green tea, berberine, thymoquinone and cannabidiol are compounds isolated from medicinal plants. These agents showed action through induction of apoptosis, down regulation of inflammation, epigenetics, hormonal modulation, among other. In vitro effect against cancer cells, in vivo experiments mainly with murine model and clinical trials reassured their efficacy against breast cancer. A protective effect against recurrence cases and chemosensitization to standard drugs was also successful. The use of nanotechnology provided a optimize delivery of these therapeutical molecules. Taken together this information led us to acknowledgement that we do probably have the natural agents for a future adjuvant treatment against breast cancer.
Author: Isadora De F√°tima Braga Magalh√£es Publisher: ISBN: Category : Electronic books Languages : en Pages : 0
Book Description
The importance of a new anticancer drug for breast cancer is well established. Natural compounds that can prevent this disease or be used as an adjuvant treatment associated with conventional drugs could be the solution for this. This chapter is an overview of agents extracted from plants with outstand results in the last six years. Green tea, berberine, thymoquinone and cannabidiol are compounds isolated from medicinal plants. These agents showed action through induction of apoptosis, down regulation of inflammation, epigenetics, hormonal modulation, among other. In vitro effect against cancer cells, in vivo experiments mainly with murine model and clinical trials reassured their efficacy against breast cancer. A protective effect against recurrence cases and chemosensitization to standard drugs was also successful. The use of nanotechnology provided a optimize delivery of these therapeutical molecules. Taken together this information led us to acknowledgement that we do probably have the natural agents for a future adjuvant treatment against breast cancer.
Author: Mani T. Valarmathi Publisher: ISBN: 9781839692031 Category : Breast Languages : en Pages : 0
Book Description
In recent years, there has been substantial development in breast cancer research and its clinical applications, for example, breast cancer biology and genomics, epidemiology and prevention, early detection and screening, and diagnosis and treatment. As such, this book consolidates recent advances in breast cancer biology and therapeutics, covering a broad spectrum of interrelated subjects. Chapters cover topics such as pathobiology of breast cancer, biomarkers, in vitro models of breast cancer, pharmacotherapy, screening and management, diagnostic imaging, and more. This book is a valuable resource for medical and allied health students as well as researchers and clinicians.
Author: Mohd Sayeed Akhtar Publisher: Springer ISBN: 981108064X Category : Science Languages : en Pages : 561
Book Description
This volume provides summarized scientific evidence of the different classes of plant-derived phytocompounds, their sources, chemical structures, anticancer properties, mechanisms of action, methods of extraction, and their applications in cancer therapy. It also discusses endophyte-derived compounds as chemopreventives to treat various cancer types. In addition, it provides detailed information on the enhanced production of therapeutically valuable anticancer metabolites using biotechnological interventions such as plant cell and tissue culture approaches, including in vitro-, hairy root- and cell-suspension culture; and metabolic engineering of biosynthetic pathways. Anticancer Plants: Natural Products and Biotechnological Implements – Volume 2” explores the natural bioactive compounds isolated from plants as well as fungal endophytes, their chemistry, and preventive effects to reduce the risk of cancer. Moreover, it highlights the genomics/proteomics approaches and biotechnological implementations. Providing solutions to deal with the challenges involved in cancer therapy, the book benefits a wide range of readers including academics, students, and industrial experts working in the area of natural products, medicinal plant chemistry, pharmacology, and biotechnology.
Author: Goutam Brahmachari Publisher: Elsevier ISBN: 0128212780 Category : Science Languages : en Pages : 386
Book Description
Discovery and Development of Anti-Breast Cancer Agents from Natural Products presents cutting-edge research advances in the field of bioactive natural products and natural drug formulations. This volume in the Natural Products Drug Discovery series focuses on molecules of natural origin and their synthetic analogs that show promising potential to act as anti-breast cancer and chemotherapeutic agents. Combining foundational background information on cancer mechanisms with details of medicinal structures from natural products, this volume compiles the latest developments from across interdisciplinary fields. Discovery and Development of Anti-Breast Cancer Agents from Natural Products will serve as a valuable resource for researchers working to discover promising leads for the development of novel pharmaceuticals for breast cancer, highlighting a number of key structures from natural products and exploring possible future developments in the area. Highlights active agents from natural sources for development as novel anti-cancer agents Features contributions from active researchers and leading experts working in the field Includes foundational background information on both breast cancer mechanisms and natural product structures to support researchers from different disciplines
Author: Abderrazak El Alami Publisher: Lulu.com ISBN: 9781447707592 Category : Health & Fitness Languages : en Pages : 0
Book Description
Breast cancer is the most commonly diagnosed cancer type, accounting for 1 in 8 cancer diagnoses worldwide. Side effects and the development of resistance to treatment, especially to chemotherapy, radiotherapy and hormonal therapy are major obstacles to the effective treatment of breast cancer. Recently, natural products from medicinal plants have gained immense attention as potential breast cancer prevention and therapeutics because of their anti-breast cancer effects. Medicinal plants are beneficial to human health because they contain bioactive compounds responsible for their therapeutic effects. Countless recent studies have confirmed that a large number of plants, traditionally used by local people, are rich sources of bioactive compounds which provide health benefits and also possess strong anti-breast cancer effects. Many plants have antioxidant, antimutagenic, anticarcinogenic, antimicrobial, anti-inflammatory activities that play important roles in cancer prevention. Several plants with antioxidant, antimicrobial, anti-inflammatory, antimutagenic, anticarcinogenic, antiproliferative, antitumor, antimetastasis, antiangiogenesis, immunomodulatory and hepatoprotective activities can play important roles in the treatment of cancers. This book focuses on the main plants, used as food and/or in herbal medicine, that are rich in bioactive compounds with anti-breast cancer activities and proprieties. We provide the common and scientific names of all plants, their main bioactive compounds with anti-breast cancer effects, and their activities and properties against breast cancer. To facilitate the identification of each plant, we give a photo of the used parts for each plant. All data are based on the results of recent scientific studies (377 references, with links to each publication).
Author: Pandurangan, Ashok Kumar Publisher: IGI Global ISBN: 1799892603 Category : Medical Languages : en Pages : 643
Book Description
Many chemotherapeutic agents are available in today’s market that are highly effective against a variety of cancer types; however, the major drawbacks of these chemotherapeutic agents are the many side effects. As an alternative to these chemotherapeutic agents, there are a number of natural agents that are effective against cancer that have been tested in preclinical and clinical models over the years. These natural products must be documented and discussed in order to provide a thorough overview of all the options available for cancer treatment. The Handbook of Research on Natural Products and Their Bioactive Compounds as Cancer Therapeutics emphasizes the list of natural agents against all types of cancers and discusses the current state of research in the fields of natural products and their derivatives against cancer in preclinical and clinical models. This book also provides insight into the applications of meditation and mindfulness-based interventions in clinical and non-clinical conditions. Covering topics such as cancer therapy, antioxidants, and flavonoids, it is ideal for students, research scholars, academicians, professors, scientists, oncologists, doctors, and medical practitioners.
Author: Anupam Bishayee Publisher: MDPI ISBN: 3038973106 Category : Electronic books Languages : en Pages : 285
Book Description
This book is a printed edition of the Special Issue "Natural Products for Cancer Prevention and Therapy" that was published in Nutrients
Author: Motamarri Venkata Naga Lalitha Chaitanya Publisher: Bentham Science Publishers ISBN: 9815124706 Category : Medical Languages : en Pages : 325
Book Description
This book provides a holistic view of natural products and remedies that have been used to treat cancer. The editors aim to educate readers about the importance of the translational role of natural products in cancer treatment by compiling 14 chapters. The book emphasizes an integrative approach to the topic by blending traditional knowledge that supports alternative therapies with the science of phytochemicals and drug discovery technologies as a means to manage the disease. Key topics include alternative therapies (such as aromatherapy and immune boosting herbal medications), cytotoxic and anti-cancer phytochemicals, drug delivery and discovery technologies (including high-throughput screening) and some drug targets of interest for cancer treatment (such as topoisomerases and caspases). Readers will be able to learn about natural sources of ant-cancer compounds, and the methods used by research and development experts in pharmaceutical and nutraceutical industries to isolate and formulate these compounds. This book will be a handy resource for a wide range of readers. This includes researchers, traditional medical practitioners, PG students, Ph.D. scholars and general readers to understand the role of natural products in cancer treatment. key features - Explains the importance of alternative therapies in the management of cancer - Emphasizes the ethnopharmacological approaches to cancer - Explores natural anticancer drug libraries - Discusses the role of modern cancer targets and the importance of in-silico tools in anticancer drug discovery - Addresses modern drug discovery tools and drug delivery technologies concerning their applications in cancer treatment. - Includes references for further reading
Author: Iris F. F. Benzie Publisher: CRC Press ISBN: 1439807167 Category : Health & Fitness Languages : en Pages : 500
Book Description
The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef
Author: Spyridon E. Kintzios Publisher: CRC Press ISBN: 0429616171 Category : Science Languages : en Pages : 504
Book Description
An increasing amount of cancer research is being directed towards the investigation of plant-derived anticancer compounds, many of which have been used in traditional herbal treatments for centuries. Plants that Fight Cancer is an up-to-date, extensive review of plant genera and species with documented anti-tumor and anti-leukaemic properties. Following an overview of the disease and the diverse methods of therapy and clinical testing, the book provides a detailed examination of the plants whose compounds are currently used in conventional cancer treatment, the species which show the greatest potential as future candidates, and other species with established anticancer properties. The third section explores each of more than 150 terrestrial plant genera and species, with a review of their traditional uses, mythology, botany, active ingredients, and product applications, along with photographs and illustrations and an analysis of expected results and risks. The text closes with a discussion of algal extracts and isolated metabolites with anticancer activity, a summary of published research for each species, and chemical structures of the most important compounds.
Author: Isadora De F√°tima Braga Magalh√£es
Author: Isadora De F√°tima Braga Magalh√£es
Author: Mani T. Valarmathi
Author: Mohd Sayeed Akhtar
Author: Goutam Brahmachari
Author: Abderrazak El Alami
Author: Pandurangan, Ashok Kumar
Author: Anupam Bishayee
Author: Motamarri Venkata Naga Lalitha Chaitanya
Author: Iris F. F. Benzie
Author: Spyridon E. Kintzios