Author: Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
The Use of Biomarkers in Environmental Exposure Assessment
Author: IEH Report on the Use of Biomarkers in Environmental Exposure Assessment
Author: Medical Research Council (Great Britain). Institute for Environment and HealthPublisher:
ISBN:
Category : Air
Languages : en
Pages : 124
Book Description
Use of Biomarkers in Assessing Health and Environmental Impacts of Chemical Pollutants
Author: Curtis C. TravisPublisher: Springer Science & Business Media
ISBN: 1489920528
Category : Medical
Languages : en
Pages : 283
Book Description
Biological markers (biomarkers) are useful tools for understanding the nature and extent of human exposure and risk from environmental toxicants. Biomarkers are classified into three basic categories: exposure, effect, or susceptibility. A marker of exposure is the product of the interaction between a target cell or molecule and a foreign substance (NAS, 1989). These markers can be used to determine the biologically effective dose necessary to elicit a particular physiological change in an organism. A marker of effect is a biochemical or physiological change in an organism that can predict the onset of adverse health effects resulting from a given exposure. Lastly, markers of susceptibility act as indicators of an inherent or acquired tendency of an organism to experience an adverse health effect (NAS, 1989). These markers are already used to detect a variety of diseases and show great promise for developing a better understanding of the mechanicisms of disease. Additionally, biomarkers can be used to establish a more rational basis for quantitative risk extrapolation between species, as weIl as to obtain more precise estimates of the time of critical exposure. These markers can also prove helpful in identifying potentially damaging exposures before the onset of adverse health effects. Biomarkers serve as a valuable exposure assessment tool because they take into account exposure from all routes and integrate exposure from all sources. They have the potential to yield better risk estimates than current monitoring and modeling protocols. In lune 1992, Dr. Travis and Dr.
Exposure Assessment in Environmental Epidemiology
Author: Mark J. NieuwenhuijsenPublisher: Oxford University Press, USA
ISBN: 0199378789
Category : Medical
Languages : en
Pages : 417
Book Description
This completely updated edition of Exposure Assessment in Environmental Epidemiology offers a practical introduction to exposure assessment methodologies in environmental epidemiologic studies. In addition to methods for traditional methods -- questionnaires, biomonitoring -- this new edition is expanded to include geographic information systems, modeling, personal sensoring, remote sensing, and OMICs technologies. In addition, each of these methods is contextualized within a recent epidemiology study, maximizing illustration for students and those new to these to these techniques. With clear writing and extensive illustration, this book will be useful to anyone interested in exposure assessment, regardless of background.
Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment
Author: National Research CouncilPublisher: National Academies Press
ISBN: 0309112982
Category : Science
Languages : en
Pages : 300
Book Description
The new field of toxicogenomics presents a potentially powerful set of tools to better understand the health effects of exposures to toxicants in the environment. At the request of the National Institute of Environmental Health Sciences, the National Research Council assembled a committee to identify the benefits of toxicogenomics, the challenges to achieving them, and potential approaches to overcoming such challenges. The report concludes that realizing the potential of toxicogenomics to improve public health decisions will require a concerted effort to generate data, make use of existing data, and study data in new waysâ€"an effort requiring funding, interagency coordination, and data management strategies.
Bioindicators and Biomarkers of Environmental Pollution and Risk Assessment
Author: Jamil KaiserPublisher:
ISBN:
Category : Nature
Languages : en
Pages : 230
Book Description
Provides the reader with an overview of the variety of animal and plants that are available for use as environmental monitors. The author emphasizes that the use of a single species of target bioindicator is not appropriate or scientifically sound for the monitoring of several toxic pollutants.
The Role and Potential Use of Biomarkers in Environmental Exposure Assessments
Author: Timothy ChandlerUse of Biomarkers for Environmental Quality Assessment
Author: Jean-Claude AmiardPublisher: CRC Press
ISBN: 1000448371
Category : Technology & Engineering
Languages : en
Pages : 370
Book Description
This work is primarily designed for any person or organization in charge of assessment of the quality of natural resources and of pollution prevention.
Nondestructive Biomarkers in Vertebrates
Author: Cristina FossiPublisher: CRC Press
ISBN: 1000724301
Category : Medical
Languages : en
Pages : 378
Book Description
Nondestructive Biomarkers in Vertebrates presents an innovative approach for hazard assessment in vertebrates based on nondestructive rather than destructive methods. The book reviews the state of the art and defines the development and validation procedure of this new strategy. Biological materials, such as blood samples, epithelial tissue, eggs, feathers, and feces that can be obtained without stress or damage to the animal are suggested. Certain traditional studies (blood esterases, blood chemistry, mixed function oxidases, porphyrins, DNA damage, and cytological changes) can be performed on these specimens, along with new tests requiring only very small samples. This approach is developed to benefit protected, threatened species whose existence cannot be further jeopardized by the use of destructive methods. This volume will be particularly useful to ecotoxicologists, wildlife protection personnel, environmental consultants, and conservationist organizations.
Biological Monitoring
Author: M. E. ContiPublisher: WIT Press
ISBN: 1845640020
Category : Technology & Engineering
Languages : en
Pages : 257
Book Description
The aim of this book is to provide the reader with a basic understanding of the use of bioindicators both in assessing environmental quality and as a means of support in environmental impact assessment (EIA) procedures.