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Author: Daniel Godfrey Publisher: Titan Books (US, CA) ISBN: 1785653180 Category : Fiction Languages : en Pages : 351
Book Description
The new thrilling sci-fi novel from the author of New Pompeii and Empire of Time In a future London, humans are watched over by AIs and served by bots. But now that justice and jobs are meted out by algorithm, inequality blooms, and protest is brutally silenced. Anna Glover may be the most hated woman in the troubled city - the media's scapegoat for an unpopular war. Now she hides from the public eye, investigating neglected cases by using the mind-invading technology of the synapse sequencer to enter witnesses' memories. When a PI brings her a new high-stakes case, Anna sees a chance for atonement. But soon she is drawn into a plot that threatens to upend her hard-won anonymity and put everyone in danger - even those she hopes to save.
Author: Daniel Godfrey Publisher: Titan Books (US, CA) ISBN: 1785653180 Category : Fiction Languages : en Pages : 351
Book Description
The new thrilling sci-fi novel from the author of New Pompeii and Empire of Time In a future London, humans are watched over by AIs and served by bots. But now that justice and jobs are meted out by algorithm, inequality blooms, and protest is brutally silenced. Anna Glover may be the most hated woman in the troubled city - the media's scapegoat for an unpopular war. Now she hides from the public eye, investigating neglected cases by using the mind-invading technology of the synapse sequencer to enter witnesses' memories. When a PI brings her a new high-stakes case, Anna sees a chance for atonement. But soon she is drawn into a plot that threatens to upend her hard-won anonymity and put everyone in danger - even those she hopes to save.
Author: Wulfram Gerstner Publisher: Cambridge University Press ISBN: 1107060834 Category : Computers Languages : en Pages : 591
Book Description
This solid introduction uses the principles of physics and the tools of mathematics to approach fundamental questions of neuroscience.
Author: Ron Sun Publisher: Springer ISBN: 354044565X Category : Computers Languages : en Pages : 400
Book Description
Sequential behavior is essential to intelligence in general and a fundamental part of human activities, ranging from reasoning to language, and from everyday skills to complex problem solving. Sequence learning is an important component of learning in many tasks and application fields: planning, reasoning, robotics natural language processing, speech recognition, adaptive control, time series prediction, financial engineering, DNA sequencing, and so on. This book presents coherently integrated chapters by leading authorities and assesses the state of the art in sequence learning by introducing essential models and algorithms and by examining a variety of applications. The book offers topical sections on sequence clustering and learning with Markov models, sequence prediction and recognition with neural networks, sequence discovery with symbolic methods, sequential decision making, biologically inspired sequence learning models.
Author: Max R. Bennett Publisher: CRC Press ISBN: 0203302540 Category : Science Languages : en Pages : 351
Book Description
The History of the Synapse provides a history of those discoveries concerning the identification and function of synapses that provide the foundations for research during this new century with a personal view of the process by which new concepts have developed. Previously published as essays, the chapters in this book provide a history of various aspects of synaptic function, beginning with the evolution over two and a half thousand years and how progress was made in the establishment of a conceptual structure that would allow the synapse to be identified at the beginning of the 20th century. Numerous illustrations explain either the technical approach or the experimental finding.
Author: Virginia M. Pickel Publisher: Elsevier ISBN: 0124186823 Category : Medical Languages : en Pages : 529
Book Description
The Synapse summarizes recent advances in cellular and molecular mechanisms of synaptic transmission and provides new insights into neuronal plasticity and the cellular basis of neurological diseases. - Part 1 provides an in-depth look at structural differences and distribution of various pre- and post-synaptic proteins found at glutamatergic synapses. - Part 2 is dedicated to dendritic spines and their associated perisynaptic glia, which together constitute the tripartite synapse. The spines are portrayed as major sites for calcium sequestration and local protein synthesis. - Part 3 highlights the important regional and cellular differences between glutamatergic transmission and that of neurotransmitters such as dopamine and acetylcholine that are commonly found in axon terminals without synaptic membrane specializations. - Part 4 provides an overview of the synapse from the time of formation to degeneration under the powerful influence of aging or hormonal decline that leads to severe deficits in cognitive function. Each chapter is illustrated with drawings and images derived from calcium imaging, electron microscopic immunolabeling, or electrophysiology. This book is a valuable reference for neuroscientists and clinical neurologists in both research and clinical settings. - A comprehensive reference focused on the structure and function of the synapse - Covers the links between the synapse and neural plasticity and the cellular basis of neurologic disease - Detailed coverage of dendritic spines and associated perisynaptic glia—the tripartite synapse - Includes in-depth coverage of synapse degeneration due to aging or hormonal decline related to severe cognitive impairment
Author: Rodolfo Riascos Llinás Publisher: ISBN: 9780195116526 Category : Medical Languages : en Pages : 234
Book Description
The squid giant synapse is the single most important model for investigating the transmitter release mechanism in chemical junctions. This unique book, by a leading expert in the field, gives a concise overview of all that has been learned about synaptic transmission in this superb model system. It covers in detail the biophysics of the voltage-dependent calcium currents, calcium concentration microdomains, and much of the molecular basis for the triggering of the secretory event. Ideal for graduate and undergraduate courses, the book includes PC and Macintosh versions of two programs for simulating and manipulating any aspect of synaptic transmission. One program is a modeling tool designed for working neuroscientists, and the other teaches the basic principles of synaptic transmission by allowing students to alter the parameters, essentially without limits, and see the effects on the action potential over time. Anyone studying this central topic of neuroscience will find this book an invaluable resource.
Author: National Academy of Sciences Publisher: National Academies Press ISBN: 0309045290 Category : Medical Languages : en Pages : 195
Book Description
The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."
Author: Johannes W. Hell Publisher: Springer Science & Business Media ISBN: 0387772324 Category : Medical Languages : en Pages : 801
Book Description
This new Springer volume, which comes complete with a free DVD, is a comprehensive and detailed overview of the synapse with emphasis on the glutamatergic synapse. Most chapters relate the synapse’s functional aspects to its molecular mechanisms. This approach shows which mechanisms are characterized on both the functional and structural level and can thus be considered firmly established. It’s an important text for neuroscientists and disease-oriented clinicians in neurology.
Author: Linda S. Costanzo Publisher: Elsevier Health Sciences ISBN: 1455728136 Category : Medical Languages : en Pages : 517
Book Description
Physiology is a comprehensive presentation of core physiologic concepts with a focus on mechanisms. Renowned physiology instructor Linda S. Costanzo covers important concepts in the field, both at the organ system and cellular levels. Easy to read and user-friendly, the revised fourth edition stresses essential and relevant content with absolute clarity and includes concise step-by-step explanations complemented by numerous tables and abundant illustrations. It provides information on the underlying principles of cellular physiology, the autonomic nervous system, and neurophysiology, as well as the cardiovascular, respiratory, renal, acid-base, gastrointestinal, endocrine, and reproductive organ systems. This book is ideal as both a textbook and as a review guide for the boards. Provides step-by-step explanations and easy-to-follow diagrams clearly depicting physiologic principles. Integrates equations and sample problems throughout the text. Presents chapter summaries for quick overviews of important points. Contains boxed Clinical Physiology Cases to provide you with more clinical examples and a more thorough understanding of application. Provides questions at the end of each chapter for an extensive review of the material and to reinforce your understanding and retention. Offers a full-color design and all full-color illustrations throughout. Features increased coverage of pathophysiology in the neurophysiology, gastrointestinal, renal, acid-base, and endocrine chapters to emphasize this important component of the USMLE exam. Incorporates further practice in solving physiology equations through the inclusion of additional problem-solving questions throughout the text.
Author: Daniel Godfrey
Author: Daniel Godfrey
Author: Wulfram Gerstner
Author: Ron Sun
Author: Max R. Bennett
Author: Virginia M. Pickel
Author: Rodolfo Riascos Llinás
Author: National Academy of Sciences
Author: Johannes W. Hell
Author: Paul Bousfield
Author: Linda S. Costanzo