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Author: L.S. Hnilica Publisher: CRC Press ISBN: 1351085395 Category : Medical Languages : en Pages : 224
Book Description
This book endeavours to present an analysis of the current knowledge of the structure properties and possible functions of histones. The broad scope of this topic prevents the discussion of certain individual aspects in any detail. For this purpose, some of the more specialised review articles should be consulted. However, the present volume will contribute to a more general understanding of histone biochemistry and will provide stimulation, as well as source references, to the student of the cell nucleus and its functions.
Author: L.S. Hnilica Publisher: CRC Press ISBN: 1351085395 Category : Medical Languages : en Pages : 224
Book Description
This book endeavours to present an analysis of the current knowledge of the structure properties and possible functions of histones. The broad scope of this topic prevents the discussion of certain individual aspects in any detail. For this purpose, some of the more specialised review articles should be consulted. However, the present volume will contribute to a more general understanding of histone biochemistry and will provide stimulation, as well as source references, to the student of the cell nucleus and its functions.
Author: Lubomir S. Hnilica Publisher: ISBN: Category : Medical Languages : en Pages : 246
Book Description
This book endeavours to present an analysis of the current knowledge of the structure properties and possible functions of histones. The broad scope of this topic prevents the discussion of certain individual aspects in any detail. For this purpose, some of the more specialised review articles should be consulted. However, the present volume will contribute to a more general understanding of histone biochemistry and will provide stimulation, as well as source references, to the student of the cell nucleus and its functions.
Author: Chang-Hui Shen Publisher: Nova Science Publishers ISBN: 9781621002741 Category : Histones Languages : en Pages : 0
Book Description
Histones are DNA-binding proteins that help in the packaging of DNA to fit into the cell nucleus in a hierarchy of organization. During the packaging and unfolding process, histones are involved in crucial biological activities at the molecular level. This book presents research in the study of histone class, structure and function, including the roles of linker histones in chromatin structure, the post-translational modifications of histones and the importance of chromatin structure and epigenetics in gene regulation and carcinogenesis. (Imprint: Nova)
Author: Gary S. Stein Publisher: CRC Press ISBN: 9780849355158 Category : Science Languages : en Pages : 426
Book Description
This comprehensive book is a compilation of Professor Lubomir S. Hnilica's twenty years of research experimentally addressing the chemistry and the biological functions of chromosomal proteins. The histones and other nuclear proteins found associated with DNA in a number of tissues and cell types are featured. Lubomir Hnilica played a major role in establishing the extent to which these basic chromosomal polypeptides are conserved and the manner in which they interact with DNA to modify chromatin structure. In addition, non-histone chromosomal protein research is explained, and his technique of applying several biochemical and immunological approaches to the characterization of this complex and heterogeneous class of chromosomal polypeptides is discussed. Highlighted is the use of chemical crosslinking for studying protein/DNA interactions in intact cells. The proteins as well as the structure, organization, and regulation of the genes are also presented.
Author: Chang-Hui Shen Publisher: Nova Science Publishers ISBN: 9781621003731 Category : Histones Languages : en Pages : 268
Book Description
Histones are DNA-binding proteins that help in the packaging of DNA to fit into the cell nucleus in a hierarchy of organization. During the packaging and unfolding process, histones are involved in crucial biological activities at the molecular level. This book presents research in the study of histone class, structure and function, including the roles of linker histones in chromatin structure, the post-translational modifications of histones and the importance of chromatin structure and epigenetics in gene regulation and carcinogenesis.
Author: Renato Paro Publisher: Springer Nature ISBN: 3030686701 Category : Science Languages : en Pages : 215
Book Description
This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading this book, the student will: Have an understanding of the basic toolbox of epigenetic regulation Know how genetic and epigenetic information layers are interconnected Be able to explain complex epigenetic phenomena by understanding the structures and principles of the underlying molecular mechanisms Understand how misregulated epigenetic mechanisms can lead to disease
Author: David W. FitzSimons Publisher: John Wiley & Sons ISBN: 0470717785 Category : Science Languages : en Pages : 192
Book Description
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Author: D. M. Philips Publisher: Springer Science & Business Media ISBN: 1468418157 Category : Science Languages : en Pages : 315
Book Description
The histones are now a very well established part of Biochemistry. The interpretation of all that is known about them, however, is already too great a burden for a single author to undertake. Indeed, a survey of the indexed literature shows that the number of publications on the histones has approximately doubled in every three years for the past 15 years, and is now several hundred a year. It is time then to bring together in one publication the major topics embraced by this great research effort. This book therefore endeavours to give, in six chapters, a broad and searching account of the biochemistry and biophysics of these interesting proteins and their complexes with nucleic acids, the nucleohistones. Each chapter is written by different authors who are all active in this research and who have had many years experience with these proteins and their complexes. Chapters 1, 2, part of 3, and all of Chapters 5 and 6, cover the occurrence, preparation, characterization, sequence structure, bio physical properties and finally, the biosynthesis and functions of the histones. The other part of Chapter 3, the whole of Chapter 4 and to a less extent some other chapters, all discuss the properties and structure of the nucleohistones. The study of these complexes is undoubtedly of great importance in bridging the gaps in our knowledge of template activity and differentiation as well as of chromosomal structure and mechanics.
Author: L.S. Hnilica
Author: L.S. Hnilica
Author: Lubomir S. Hnilica
Author: Chang-Hui Shen
Author: Gary S. Stein
Author: 
Author: Lubomir S. Hnilica
Author: Chang-Hui Shen
Author: Renato Paro
Author: David W. FitzSimons
Author: D. M. Philips