A Symposium: The Role of Calcium Antagonists in Hypertension PDF Download

Author: Symposium the Role of Calcium Antagonists in Hypertension (1991, New York, NY)
Publisher:
ISBN:
Category :
Languages : en
Pages : 42

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Author: Kyuzo Aoki
Publisher: Springer Science & Business Media
ISBN: 4431680489
Category : Medical
Languages : en
Pages : 375

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Book Description
This volume contains papers presented at the First International Symposium on Mechanism and Treatment in Essential Hyperten sion, which was held on October 23 and 24, 1985 in Nagoya, Japan. The meeting was an official satellite symposium to the meeting of the Fifth International Symposium on Rats with Spon taneous Hypertension and Related Studies in Kyoto, October 20-22, 1985. The Nagoya symposium was made possible by offi cial grants from the city of Nagoya and Aichi Prefecture and the generous financial support of many companies. The aim of the symposium was to provide a forum for presen tation and discussion of recent advances in the area of essential hypertension, particularly with regard to calcium mechanisms in vasoconstriction and vasodilation in arterial vessels and the func tion of arterial smooth muscle. The role of calcium ions in the function of arterial smooth muscle has attracted a great deal of attention in the last two decades. The mode of action of calcium ions was revealed at the molecular level. The hypertension model of the spontaneously hypertensive rat has been widely utilized for research into the fundamental mechanisms of genetic hyperten sion, stroke, and cardiovascular disease as well as into therapeutic measures. New tools of calcium agonists and antagonists have become available to research into the mechanism, prevention, and treatment of essential hypertension at the molecular, subcellular, and cellular levels of arterial smooth muscle, at the organ level of arterial vessels, as well as at the total systemic level.

Author: Lionel H. Opie
Publisher: Springer Science & Business Media
ISBN: 1461308631
Category : Medical
Languages : en
Pages : 315

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Calcium antagonists are now regarded as the most important advance in cardiac drug therapy since the advent of beta-adrenergic blocking agents. Acting ba sically as vasodilators-though with many other com plex mechanisms especially in the case of the anti arrhythmic calcium antagonists, these agents have grown in importance to become among the therapeutic agents of first choice for angina pectoris and hyper tension. The major aim of the present book is to present the clinician with the information needed for the practical use of calcium antagonists. What do all the numerous and often conflicting trials say? Do these agents really work? If so, which agent and in what dose? How do the three front runners, verapamil, nifedipine and diltia zem compare in the efficacy and side-effects with each other? How do the new second generation agents, now entering the North American market, slot in and com pare with the three first-liners? When the gloss is taken away from the advertisements, what is really left? The strong clinical bias of the present book should be complimented by further reading of books slanted towards fundamentals. One of the most important and recent of these is that by Dr Winifred Nayler (Calcium Antagonists, Academic Press, 1988). That book should be basic for essential background knowledge in the area of calcium antagonists. The important basic contribu tions of Fleckenstein deserve emphasis.

Author: Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure
Publisher:
ISBN:
Category : Hypertension
Languages : en
Pages : 20

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Author: C. Romanini
Publisher: CRC Press
ISBN: 9781850704683
Category : Medical
Languages : en
Pages : 174

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This is a clinician's and researcher's reference text on using calcium antagonists - calcium channel blockers - in the treatment of gestational hypertension and pre-eclampsia. It contains twelve chapters covering experimental and clinical studies on the major calcium antagonists, their definition and classification and pharmacological profile, which drugs to use and when and which drugs to avoid. It also describes nifedipine pharmacodynamics and pharmacokinetics and covers nifedipine first-line treatment of gestational hypertension and pre-eclampsia along with chapters on second-line treatment and nifedipine blood cells and blood rheology. The book provides a comparison between two calcium antagonists in treating gestational hypertension and new categories to classify pre-eclampsia. Includes bibliographic references and index.

Author: Aram V. Chobanian
Publisher:
ISBN:
Category :
Languages : en
Pages : 42

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Author: Théophile Godfraind
Publisher: Birkhäuser
ISBN: 3034878591
Category : Medical
Languages : en
Pages : 269

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The main effect of calcium channel blockers is the blockade of calcium entry into cells through voltage operated calcium channels. This volume gives a comprehensive overview of the different classes of CCBs and their various effects. It covers historical development, pharmacology, clinical aspects, and perspectives. All chapters are written by Prof. T. Godfraind, a world leading expert in the field.

Author: Murray Epstein
Publisher:
ISBN: 9781560534969
Category : Medical
Languages : en
Pages : 874

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This thoroughly revised and expanded new edition presents the current state of knowledge of the diverse applications of calcium antagonists and makes recommendations about their appropriate use. New sections have been added on Clinical Pharmacology and Metabolic Effects. Sixteen new chapters have been added on such topics as Pharmacogenetics of Hypertension: Using Gene Markers to Infer Pathogenesis and Guide Therapy, New Pharmacologic Directions for Calcium Channel Blockers, Calcium Channel Blocker Use in End-Stage Renal Disease: Pharmacokinetics and Pharmacodynamics, and many others. Significantly expanded from previous edition with 16 new chapters on hot topics A comprehensive reexamination of the safety of calcium antagonists in light of many newly reported clinical trials Elucidates the evolving role of calcium antagonists in the antihypertensive armamentarium, especially in the patient with diabetes Explores beneficial effects of calcium antagonists in attenuating atherosclerosis in the context of newly reported clinical trials, including ELSA. Written by world-renowned experts in the field Emphasizes evidence-based studies New chapters have been added on such topics as Pharmacogenetics of Hypertension: Using Gene Markers to Infer Pathogenesis and Guide Therapy, New Pharmacologic Directions for Calcium Channel Blockers, Calcium Channel Blocker Use in End-Stage Renal Disease: Pharmacokinetics and Pharmacodynamics.

Author:
Publisher:
ISBN:
Category : Angiotensin converting enzyme
Languages : en
Pages : 154

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Author: Jeffrey K. Aronson
Publisher: Elsevier
ISBN: 0444537163
Category : Medical
Languages : en
Pages : 7629

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Book Description
Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions, Sixteenth Edition, Seven Volume Set builds on the success of the 15 previous editions, providing an extensively reorganized and expanded resource that now comprises more than 1,500 individual drug articles with the most complete coverage of adverse reactions and interactions found anywhere. Each article contains detailed and authoritative information about the adverse effects of each drug, with comprehensive references to the primary literature, making this a must–have reference work for any academic or medical library, pharmacologist, regulatory organization, hospital dispensary, or pharmaceutical company. The online version of the book provides an unparalleled depth of coverage and functionality by offering convenient desktop access and enhanced features such as increased searchability, extensive internal cross-linking, and fully downloadable and printable full-text, HTML or PDF articles. Enhanced encyclopedic format with drug monographs now organized alphabetically Completely expanded coverage of each drug, with more than 1,500 drug articles and information on adverse reactions and interactions Clearer, systematic organization of information for easier reading, including case histories to provide perspective on each listing Extensive bibliography with over 40,000 references A must–have reference work for any academic or medical library, pharmacologist, regulatory organization, hospital dispensary, or pharmaceutical company