The Relationship Between Platelet-vessel Wall Interaction Thrombosis and Atherosclerosis PDF Download

Author: I. F. Lane
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Author: R. Michael Pittilo
Publisher: Springer Science & Business Media
ISBN: 1447114558
Category : Medical
Languages : en
Pages : 205

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Book Description
The publication of Platelet-Vessel Wall Interactions, the second monograph in the Bloomsbury Series in Clinical Science, is particu larly welcome as its appearance signifies the further development of the Series and its potential for the future. The theme of this monograph is the pathophysiology of atherosclerosis, a topic that symbolises the aim of the Series, namely to highlight the important interfaces between basic medical science and clinical practice. Our congratulations to the Editors and contributors. London, December 1987 lack Tinker Preface In the Western world, atherosclerosis causes more illness and death than any other disease. Despite its devastating effects, the pathogenesis of the disease remains a matter for hypothesis and con jecture. This monograph owes its conception to a programme of work directed towards understanding the basic pathophysiology of atherosclerosis. The circulatory system is lined by vascular endothelium which has a central role in maintaining the integrity of the vessel wall and prevent ing thrombosis. The natural equilibrium existing between normal en dothelium which supports blood flow, and platelets which serve to re pair damaged endothelium, is explored in the first two chapters. Atherosclerosis developing as a response to endothelial injury is one hypothesis which has stimulated widespread interest, and re search has largely been directed towards finding the injurious agent.

Author: R. Michael Pittilo
Publisher: Springer
ISBN: 9783540174882
Category : Medical
Languages : en
Pages : 198

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Book Description
The publication of Platelet-Vessel Wall Interactions, the second monograph in the Bloomsbury Series in Clinical Science, is particu larly welcome as its appearance signifies the further development of the Series and its potential for the future. The theme of this monograph is the pathophysiology of atherosclerosis, a topic that symbolises the aim of the Series, namely to highlight the important interfaces between basic medical science and clinical practice. Our congratulations to the Editors and contributors. London, December 1987 lack Tinker Preface In the Western world, atherosclerosis causes more illness and death than any other disease. Despite its devastating effects, the pathogenesis of the disease remains a matter for hypothesis and con jecture. This monograph owes its conception to a programme of work directed towards understanding the basic pathophysiology of atherosclerosis. The circulatory system is lined by vascular endothelium which has a central role in maintaining the integrity of the vessel wall and prevent ing thrombosis. The natural equilibrium existing between normal en dothelium which supports blood flow, and platelets which serve to re pair damaged endothelium, is explored in the first two chapters. Atherosclerosis developing as a response to endothelial injury is one hypothesis which has stimulated widespread interest, and re search has largely been directed towards finding the injurious agent.

Author: Rolando E. Rumbaut
Publisher: Biota Publishing
ISBN: 1615040404
Category : Medical
Languages : en
Pages : 77

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Platelets are essential mediators of the physiologic process of hemostasis and pathologic thrombosis. While platelets do not interact with vascular walls under normal conditions, vascular injury or inflammation result in a coordinated series of events including platelet adhesion, aggregation, and promotion of coagulation. In this review, we describe the primary mechanisms involved in these responses in various vascular beds of both macro- and microvessels, and outline key unresolved aspects of these important interactions.

Author: Georges Jolles
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 452

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Author: Michael C Berndt
Publisher: CRC Press
ISBN: 0203304322
Category : Science
Languages : en
Pages : 471

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Platelets, Thrombosis and the Vessel Wall aims to highlight the key areas of platelet function in the regulation of haemostasis and thrombosis and covers areas such as platelet production, interaction of platelets with leucocytes, mechanisms of cross-talk between platelets, leukocytes, and endothelium. The two major clinical causes of thrombosis, anti-phospholipid antibodies and genetic predisposition, are also addressed.

Author:
Publisher:
ISBN:
Category : Blood
Languages : en
Pages :

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Book Description
Platelets are essential mediators of the physiologic process of hemostasis and pathologic thrombosis. While platelets do not interact with vascular walls under normal conditions, vascular injury or inflammation result in a coordinated series of events including platelet adhesion, aggregation, and promotion of coagulation. In this review, we describe the primary mechanisms involved in these responses in various vascular beds of both macro- and microvessels, and outline key unresolved aspects of these important interactions. Table of Contents: Introduction / General Characteristics of Platelets

Author: Gundu HR Rao
Publisher: Jaypee Brothers Medical Publishers
ISBN: 9352702026
Category : Education
Languages : en
Pages : 283

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Platelets are tiny blood cells that help the body form clots to stop bleeding. Antiplatelet medications, such as aspirin and clopidogrel, are commonly used to thin the blood which limits clotting and reduces the risk of heart attack. This book is a comprehensive guide to blood platelets for haematologists. Beginning with discussion on platelet structure, morphology, function and physiology, the next chapters cover the role of calcium in platelet activation and calcium modulation by cyclic nucleotides. The following sections explain the pharmacology of antiplatelet drugs, antiplatelet therapies, aspirin resistance, and the association of diabetes mellitus with major platelet dysfunction. The book concludes with chapters on acute coronary problems, interaction between endothelial cells and platelets, and blood biocompatibility studies. Authored by a Minneapolis-based expert in the field, the text is further enhanced by clinical photographs, diagrams and tables. Key points Comprehensive guide to blood platelets for haematologists Extensive coverage of antiplatelet drugs and resistance Recognised author from University of Minnesota Highly illustrated with clinical photographs, diagrams and tables

Author: Robert Fitridge
Publisher: University of Adelaide Press
ISBN: 1922064009
Category : Medical
Languages : en
Pages : 589

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New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Author: Steen Dalby Kristensen
Publisher:
ISBN:
Category :
Languages : en
Pages : 23

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