The Promise of Biotechnology PDF Download

Author:
Publisher: DIANE Publishing
ISBN: 1428966668
Category :
Languages : en
Pages : 48

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Author: Gary P. Pisano
Publisher: Harvard Business Press
ISBN: 9781591398400
Category : Business & Economics
Languages : en
Pages : 278

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Book Description
Why has the biotechnology industry failed to perform up to expectations? This book attempts to answer this question by providing a critique of the industry. It reveals the causes of biotech's problems and offers an analysis on how the industry works. It also provides prescriptions for companies, seeking ways to improve the industry's performance.

Author: Scott Dessain
Publisher: Academic Press
ISBN: 0128092092
Category : Medical
Languages : en
Pages : 276

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Book Description
Preserving the Promise: Improving the Culture of Biotech Investment critically examines why most biotech startups fail, as they emerge from universities into an ecosystem that inhibits rather than encourages innovation. This "Valley of Death" squanders our public investments in medical research and with them, the promise of longer and healthier lives. The authors explicate the Translation Gap faced by early stage biotech companies, the result of problematic technology transfer and investment practices, and provide specific prescriptions for improving translation of important discoveries into safe and effective therapies. In Preserving the Promise, Dessain and Fishman build on their collective experience as company founders, healthcare investor (Fishman) and physician/scientist (Dessain). The book offers a forward-looking, critical analysis of "conventional wisdom" that encumbers commercialization practices. It exposes the self-defeating habits of drug development in the Valley of Death, that waste money and extinguish innovative technologies through distorted financial incentives. Explains why translation of biotech discovery into medicine succeeds so infrequently that it’s been dubbed the Valley of Death Uncovers specific decision-making strategies that more effectively align incentives, improving clinical and financial outcomes for investors, inventor/entrepreneurs, and patients Examines the critical, early stages of commercialization, where technology transfer offices and Angels act as gatekeepers to development, and where tension between short-term financial and long-term clinical aspirations sinks important technologies Deconstructs the forces driving biotech, recasts them in a proven conceptual framework, and offers practical guidance for making the system better

Author: Robert H. Carlson
Publisher: Harvard University Press
ISBN: 0674053621
Category : Science
Languages : en
Pages : 290

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“Essential reading for anyone who wishes to understand the current state of biotechnology and the opportunities and dangers it may create.” —American Scientist Technology is a process and a body of knowledge as much as a collection of artifacts. Biology is no different—and we are just beginning to comprehend the challenges inherent in the next stage of biology as a human technology. It is this critical moment, with its wide-ranging implications, that Robert Carlson considers in Biology Is Technology. He offers a uniquely informed perspective on the endeavors that contribute to current progress in this area—the science of biological systems and the technology used to manipulate them. In a number of case studies, Carlson demonstrates that the development of new mathematical, computational, and laboratory tools will facilitate the engineering of biological artifacts—up to and including organisms and ecosystems. Exploring how this will happen, with reference to past technological advances, he explains how objects are constructed virtually, tested using sophisticated mathematical models, and finally constructed in the real world. Such rapid increases in the power, availability, and application of biotechnology raise obvious questions about who gets to use it, and to what end. Carlson’s thoughtful analysis offers rare insight into our choices about how to develop biological technologies and how these choices will determine the pace and effectiveness of innovation as a public good.

Author: Russian Academy of Sciences
Publisher: National Academies Press
ISBN: 0309181348
Category : Science
Languages : en
Pages : 156

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In July 2005, the National Academies released the report Biological Science and Biotechnology in Russia: Controlling Diseases and Enhancing Security. The report offered a number of recommendations that could help restore Russia's ability to join with the United States and the broader international community in leading an expanded global effort to control infectious diseases. A proposed bilateral intergovernmental commission could play a pivotal role toward that end as cooperation moves from assistance to partnership. The report proposed the establishment of two model State Sanitary Epidemiological Surveillance Centers in Russia, more focused support of competitively selected Russian research groups as centers of excellence, the promotion of investments in biotechnology niches that are well suited for Russian companies, and expanded opportunities for young scientists to achieve scientific leadership positions in Russia. Also, the report highlighted the importance of U.S. programs that support the integration of former Soviet defense scientists with civilian researchers who had not been involved in military-related activities.

Author: John W. Hanley
Publisher:
ISBN:
Category :
Languages : en
Pages : 10

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Author: FCCSET Committee on Life Sciences and Health
Publisher:
ISBN:
Category : Bioengineering
Languages : en
Pages : 108

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Author: Federal Coordinating Council for Science, Engineering, and Technology. Committee on Life Sciences and Health
Publisher:
ISBN:
Category : Biotechnology
Languages : en
Pages : 90

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Author: A Joseph Henry Press book
Publisher: Joseph Henry Press
ISBN: 0309096219
Category : Science
Languages : en
Pages : 256

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In this update to the very popular first edition of the same name, skilled science popularizer Eric Grace helps readers understand what biotechnology is and what implications it holds for all of us. Following on the heels of the success of the first edition, this thoroughly updated version offers an in-depth and accessible review of the basics of biotechnology. Accomplished science communicator Eric Grace focuses on the ethical implications involved, the wide range of public opinions both at home and abroad, the role of the media in communicating a complicated science topic, and the formidable problems associated with patenting life itself. With an emphasis on medicine, agriculture, and the environment, Grace explores the promises and realities of biotechnology. He deals frankly with the fact that biotechnology is first and foremost a commercial activity, often driven by big business and directed by the bottom line. And as biotechnology is used more frequently in medical diagnosis and treatment, we are witness to significant setbacks and reversals, dimming hopes that were prevalent when the first edition was released. But we are also witness to the burgeoning use of the technology in forensic science where DNA analysis has become commonplace in solving crimes. Likewise, DNA analysis has been a boon to studies of human history and evolution, revealing ancient details originally thought lost to us. At the same time, new uses for genetically altered bacteria are being discovered that help us clean up the environment by breaking down or sequestering toxic chemicals. While the public remains concerned about biotechnology, there is increasing awareness of the potential benefits. This updated edition of Biotechnology Unzipped helps put the many issues in perspective and provides answers to the most important questions.

Author: Craig Holdrege
Publisher: University Press of Kentucky
ISBN: 0813129478
Category : Science
Languages : en
Pages : 274

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In 2001 the Human Genome Project announced that it had successfully mapped the entire genetic content of human DNA. Scientists, politicians, theologians, and pundits speculated about what would follow, conjuring everything from nightmare scenarios of state-controlled eugenics to the hope of engineering disease-resistant newborns. As with debates surrounding stem-cell research, the seemingly endless possibilities of genetic engineering will continue to influence public opinion and policy into the foreseeable future. Beyond Biotechnology: The Barren Promise of Genetic Engineering distinguishes between the hype and reality of this technology and explains the nuanced and delicate relationship between science and nature. Authors Craig Holdrege and Steve Talbott evaluate the current state of genetic science and examine its potential applications, particularly in agriculture and medicine, as well as the possible dangers. The authors show how the popular view of genetics does not include an understanding of the ways in which genes actually work together in organisms. Simplistic and reductionist views of genes lead to unrealistic expectations and, ultimately, disappointment in the results that genetic engineering actually delivers. The authors explore new developments in genetics, from the discovery of “non-Darwinian” adaptative mutations in bacteria to evidence that suggests that organisms are far more than mere collections of genetically driven mechanisms. While examining these issues, the authors also answer vital questions that get to the essence of genetic interaction with human biology: Does DNA “manage” an organism any more than the organism manages its DNA? Should genetically engineered products be labeled as such? Do the methods of the genetic engineer resemble the centuries-old practices of animal husbandry? Written for lay readers, Beyond Biotechnology is an accessible introduction to the complicated issues of genetic engineering and its potential applications. In the unexplored space between nature and laboratory, a new science is waiting to emerge. Technology-based social and environmental solutions will remain tenuous and at risk of reversal as long as our culture is alienated from the plants and animals on which all life depends.