Author: Stanley Joseph MannPublisher:
ISBN:
Category :
Languages : en
Pages : 112
Book Description
The Phenogenetics of Hair Mutants in the House Mouse
Author: Stanley Joseph MannEffects of the Mutant Gene Mc on Hair in the House Mouse, Mus Musculus
Author: Dennis Lon SustarsicPublisher:
ISBN:
Category : Genetics
Languages : en
Pages : 154
Book Description
Handbook of Mouse Mutations with Skin and Hair Abnormalities
Author: John P. SundbergPublisher: CRC Press
ISBN: 1000142329
Category : Medical
Languages : en
Pages : 582
Book Description
Handbook of Mouse Mutations with Skin and Hair Abnormalities presents 48 mouse mutations that are all available to the biomedical community. Many of the mouse mutations with dermatological diseases are reviewed and illustrated in detail. This popular reference book gives you a single source to use when determining which mouse mutation will best serve your needs as a biomedical tool for sophisticated research projects. The book also includes an overview of domestic animal genodermatoses to provide alternatives to mouse models that do not exist or to complement those that do. A detailed section written by renowned experts compares the biology of human and mouse skin and skin diseases in the areas of development and the use of animal models, mammalian genetics, keratin biochemistry, epidermal and hair follicle cycles and kinetics, cytokines and growth factors, keratinocyte culture systems, cutaneous carcinogenesis, cutaneous immune system, and skin changes associated with mutations of the endocrine system.
Pathology of Genetically Engineered and Other Mutant Mice
Author: John P. SundbergPublisher: John Wiley & Sons
ISBN: 1119624576
Category : Medical
Languages : en
Pages : 564
Book Description
An updated and comprehensive reference to pathology in every organ system in genetically modified mice The newly revised and thoroughly updated Second Edition of Pathology of Genetically Engineered and Other Mutant Mice delivers a comprehensive resource for pathologists and biomedical scientists tasked with identifying and understanding pathologic changes in genetically modified mice. The book is organized by body system, includes descriptions and explanations of a wide range of findings, as well as hundreds of color photographs illustrating both common and rare lesions that may be found in genetically engineered and wild type mice. The book is written by experienced veterinary and medical pathologists working in veterinary medical colleges, medical colleges, and research institutes. Covering the latest discoveries in mouse pathology resulting from advancements in biotechnology research over the last 30 years, this singular and accessible resource is a must-read for veterinary and medical pathologists and researchers working with genetically engineered and other mice. Readers will also benefit from: A thorough introduction to mouse pathology and mouse genetic nomenclature, as well as databases useful for analysis of mutant mice An exploration of concepts related to validating animal models, including the Cinderella Effect Practical discussions of basic necropsy methods and grading lesions for computational analyses Concise diagnostic approaches to the respiratory tract, the oral cavity and GI tract, the cardiovascular system, the liver and pancreas, the skeletal system, and other tissues As a one-stop and up to date reference on mouse pathology, Pathology of Genetically Engineered and Other Mutant Mice is an essential book for veterinary and medical pathologists, as well as for scientists, researchers, and toxicologists whose work brings them into contact with genetically modified mice.
An Investigation Into the Expression of the Rex Mutant in the House Mouse
Author: Frances Jane KorolenkoPublisher:
ISBN:
Category :
Languages : en
Pages : 166
Book Description
The House Mouse
Author: Karl TheilerPublisher: Springer Science & Business Media
ISBN: 3642884180
Category : Medical
Languages : en
Pages : 183
Book Description
With the advent of transgenic technology, which allows the identification of specific gene activities in developing mammalian organisms, the house mouse has once again taken a very important place in experimental research as one of the genetically best understood mammals. More than ever, molecular biologists are in need of a detailed, standardized description of the anatomy of the developing mouse embryo. In this classic compendium, now brought up to date and corrected, the author presents each stage of mouse development in photographs and micrographs using hybrids of two inbred strains as a standard. Organ systems are systematically reconstructed from fertilization until after birth. Molecular biologists tracing the effects of genetic manipulations, as well as students and researchers of developmental biology, will appreciate the renewed availability of this standard reference work for its unparalleled accuracy, its attention to anatomical detail, and the extent of its documentation.
An Annotated Catalogue of the Mutant Genes of the House Mouse
Author: Hans GrünebergPublisher:
ISBN:
Category : Animal mutation
Languages : en
Pages : 42
Book Description
Handbook of Mouse Mutations with Skin and Hair Abnormalities
Author: John P. SundbergPublisher: CRC Press
ISBN: 9780849383724
Category : Medical
Languages : en
Pages : 582
Book Description
Handbook of Mouse Mutations with Skin and Hair Abnormalities presents 48 mouse mutations that are all available to the biomedical community. Many of the mouse mutations with dermatological diseases are reviewed and illustrated in detail. This popular reference book gives you a single source to use when determining which mouse mutation will best serve your needs as a biomedical tool for sophisticated research projects. The book also includes an overview of domestic animal genodermatoses to provide alternatives to mouse models that do not exist or to complement those that do. A detailed section written by renowned experts compares the biology of human and mouse skin and skin diseases in the areas of development and the use of animal models, mammalian genetics, keratin biochemistry, epidermal and hair follicle cycles and kinetics, cytokines and growth factors, keratinocyte culture systems, cutaneous carcinogenesis, cutaneous immune system, and skin changes associated with mutations of the endocrine system.
Systematic Approach to Evaluation of Mouse Mutations
Author: John P. SundbergPublisher: CRC Press
ISBN: 1420049488
Category : Medical
Languages : en
Pages : 201
Book Description
Experts from The Jackson Laboratory and around the world provide practical advice on everything from how to establish a colony to where to go for specific mutations. The book includes information on medical photography, grafting procedures, and how to map the genes and evaluate the special biological characteristics of mice. It also discusses how to maintain a colony of mice that breed with difficulty, how to approach mapping spontaneous mutations, how to set up systems to evaluate a specific antibody, how to perform simple measurements that yield a large amount of information, and how to access mouse informatics on the Web.
Genetic Variants and Strains of the Laboratory Mouse
Author: Margaret C. GreenPublisher:
ISBN:
Category : Inbreeding
Languages : en
Pages : 504
Book Description