The Papovaviridae PDF Download

Author: Peter M. Howley
Publisher: Springer Science & Business Media
ISBN: 1475705840
Category : Medical
Languages : en
Pages : 402

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Author: Norman P. Salzman
Publisher: Springer
ISBN:
Category : Medical
Languages : en
Pages : 488

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Book Description
It has been more than twenty years since the isolation of polyoma virus and SV40, and the reports that they could produce tumors in animals and transformation of cells in culture. What was startling was that these biologic properties are associated with viruses that contain genetic in formation that is able to code for only five or six proteins. Since that time, investigations with these viruses have been in four principal areas. One major area of study has been on cells transformed by viruses that show altered growth properties and specify new viral and cellular proteins. Transformation studies have focused on the tumor (T) antigens that are specified by the virus and are required to initiate and to maintain the transformed state. Current studies on transformation are summarized in Chapter 4. The second broad area of investigation concerns replication of viruses during a lytic cycle of infection. T-antigens that are the hallmark of transformed cells are also expressed in cells that are lytically infected and are required for viral DNA replication and also function to alter rates of transcription of the early and late viral genes. Except for T-antigen, virus replication depends on the cellular enzymatic machinery and so the description of viral macromolecular synthesis has provided valuable insights into the cellular biosynthetic pathways. These studies are described in Chapters 1-3. The studies that have medical relevance concern JC and BK viruses and there is evidence of widespread exposure of human populations to these agents.

Author: John E. Craighead
Publisher: Academic Press
ISBN: 0080538487
Category : Medical
Languages : en
Pages : 466

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Book Description
Pathology and Pathogenesis of Human Viral Disease is a comprehensive reference that examines virus-induced clinical disease of humans in the context of the responsible virus and its epidemiology. Encompassing everything from cold and flu viruses to sexually transmitted diseases, this important resource describes the cellular and tissue pathological changes attributable to infection in the context of the pathogenic mechanisms involved. The author provides a comprehensive review of the older and contemporary literature, considering both the common and much rarer complications of infection. Pathology and Pathogenesis of Human Viral Disease is written from the unique perspective of the clinical pathologist. It will help clinicians and pathologists gain a better understanding of changes that occur in viral infected cells, tissues, and organs. It will also serve as a pathology source book for virologists, internists, and pediatricians. - Provides a comprehensive, worldwide perspective of viral disease pathology - Bridges the fields of pathology and virology; integrating clinical disease with cell and tissue pathology - Addresses topics from the perspective of the clinical pathologist - Illustrates unique, viral induced pathological lesions - Considers common and uncommon complications of infection

Author: Blossom Damania
Publisher: Springer Science & Business Media
ISBN: 0387689451
Category : Medical
Languages : en
Pages : 805

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Book Description
This unique book focuses on the DNA viruses in the human population that are associated with cancers. It covers most of the viruses that are thought to contribute to human malignancy. This book represents a comprehensive review of the field of DNA tumor virology. Right now, while there are books out there that cover individual viruses that are also covered in this book, there is no single book that covers this topic comprehensively. This book is the first current, comprehensive review of its kind in the market.

Author: Richard A. Harvey (Ph.D.)
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781782159
Category : Medical
Languages : en
Pages : 460

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Book Description
Now in full color, Lippincott's Illustrated Reviews: Microbiology, Second Edition enables rapid review and assimilation of large amounts of complex information about medical microbiology. The book has the hallmark features for which Lippincott's Illustrated Reviews volumes are so popular: an outline format, 450 full-color illustrations, end-of-chapter summaries, review questions, plus an entire section of clinical case studies with full-color illustrations. This edition's medical/clinical focus has been sharpened to provide a high-yield review. Five additional case studies have been included, bringing the total to nineteen. Review questions have been reformatted to comply with USMLE Step 1 style, with clinical vignettes.

Author: Frank J. Fenner
Publisher: Academic Press
ISBN: 1483257819
Category : Technology & Engineering
Languages : en
Pages : 673

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Book Description
Veterinary Virology deals with basic biomedical virology and the clinical discipline of infectious diseases. The book discusses the principles of virology as effecting future developments in the search for preventive and management of infectious diseases in animals, whether singly or as a whole herd or flock. Part I explains the principles of animal virology including the structure, composition, classification, nomenclature, cultivation, and assay of viruses. This part also discusses viral genetics, replication, and evolution (including mutation and genetic engineering). The book also reviews the pathogenesis of viruses, host resistance and susceptibility, as well as the mechanisms of persistent infections and tumor induction. Part II deals with viruses found in domestic animals; this part also explains in detail the properties, replication methods, pathogenesis, immunity, diagnosis, and control of some common viruses. The book discusses some other families of viruses of which no members are yet known as to have caused serious or important diseases in animals. Veterinarians, immunologists, virologists, molecular researchers, students, and academicians in the discipline of virology and cellular biology, as well as livestock owners will find this book helpful.

Author: V. M. Zhdanov
Publisher: CRC Press
ISBN: 9783718649112
Category :
Languages : en
Pages : 172

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Author: Thomas C. Jones
Publisher: Springer Science & Business Media
ISBN: 3642837492
Category : Medical
Languages : en
Pages : 691

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Book Description
The International Life Sciences Institute (ILSI) was estab lished in 1978 to stimulate and support scientific research and educational programs related to nutrition, toxicology, and food safety, and to encourage cooperation in these programs among scientists in universities, industry, and government agencies to assist in the resolution of health and safety issues. To supplement and enhance these efforts, ILSI has made a major commitment to supporting programs to harmon ize toxicologic testing, to advance a more uniform inter pretation of bioassay results worldwide, to promote a common understanding of lesion classifications, and to encourage wide discussion of these topics among scien tists. The Monographs on the Pathology of Laboratory Ani mals are designed to facilitate communication among those involved in the safety testing of foods, drugs, and chemicals. The complete set will cover all organ systems and is intended for use by pathologists, toxicologists, and others concerned with evaluating toxicity and carcinogen icity studies. The international nature of the project - as reflected in the composition of the editorial board and the diversity of the authors and editors - strengthens our ex pectations that understanding and cooperation will be im proved worldwide through the series. Alex Malaspina President International Life Sciences Institute Preface This book, on the integumentary system, is the seventh volume of a set prepared under the sponsorship of the International Life Sciences Institute (ILSI).

Author:
Publisher: Academic Press
ISBN: 0080583172
Category : Science
Languages : en
Pages : 394

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Book Description
Advances in Virus Research

Author: William Irving
Publisher: Taylor & Francis
ISBN: 1135321310
Category : Medical
Languages : en
Pages : 368

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Book Description
Instant Notes in Medical Microbiology covers medical microbiology from the molecular biology of infectious agents right through to the clinical management of the infected patient, including disease pathogenesis, diagnosis, and the use of antimicrobial therapy. The first section covers how micro-organisms spread and cause disease in humans, and how the human body responds to infection in general. The next three sections give a broad outline of the important properties of human infectious pathogens; split into viruses, bacteria, and eukaryotic organisms. The final sections cover laboratory diagnosis, antimicrobial chemotherapy, prevention strategies, and infection from the point of view of the patient.