Author: Rochellys Diaz Heijtz
Publisher: Elsevier Health Sciences
ISBN: 0323679013
Category : Medical
Languages : en
Pages :
Book Description
In consultation with Consulting Editor, Dr. Alan Buchman, Dr. Rocheyllys Diaz Heijtz has put together a state-of the-art issue of the Gastroenterology Clinics of North America devoted to The Microbiome: Interactions with Organ Systems, Diet, and Genetics. Clinical review articles from expert authors are specifically devoted to the following: The Role of the Microbiome of o the Female Reproductive Tract on Health and Pregnancy; Eating Disorders and the Gut Microbiota; Maturation of the Infant Microbiome Community Structure and Function; Microbe-Host Interactions in Allergic Diseases; Emerging Role of the Gut Microbiota in Neurodevelopmental Disorders; Brain-Gut-Microbiota Axis and Mood Disorders; Brain-Gut-Microbiota and ADHD; The Microbiota-Gut-Brain Axis and Postpartum Depression; and The Microbiota and Pancreatic Cancer. Readers will come away with the latest information on the microbiome and how to incorporate the information into gut health for patients.
The microbiome: Interactions with organ systems, diet, and genetics, An Issue of Gastroenterology Clinics of North America, Ebook
Author: Rochellys Diaz Heijtz
Publisher: Elsevier Health Sciences
ISBN: 0323679013
Category : Medical
Languages : en
Pages :
Book Description
In consultation with Consulting Editor, Dr. Alan Buchman, Dr. Rocheyllys Diaz Heijtz has put together a state-of the-art issue of the Gastroenterology Clinics of North America devoted to The Microbiome: Interactions with Organ Systems, Diet, and Genetics. Clinical review articles from expert authors are specifically devoted to the following: The Role of the Microbiome of o the Female Reproductive Tract on Health and Pregnancy; Eating Disorders and the Gut Microbiota; Maturation of the Infant Microbiome Community Structure and Function; Microbe-Host Interactions in Allergic Diseases; Emerging Role of the Gut Microbiota in Neurodevelopmental Disorders; Brain-Gut-Microbiota Axis and Mood Disorders; Brain-Gut-Microbiota and ADHD; The Microbiota-Gut-Brain Axis and Postpartum Depression; and The Microbiota and Pancreatic Cancer. Readers will come away with the latest information on the microbiome and how to incorporate the information into gut health for patients.
Publisher: Elsevier Health Sciences
ISBN: 0323679013
Category : Medical
Languages : en
Pages :
Book Description
In consultation with Consulting Editor, Dr. Alan Buchman, Dr. Rocheyllys Diaz Heijtz has put together a state-of the-art issue of the Gastroenterology Clinics of North America devoted to The Microbiome: Interactions with Organ Systems, Diet, and Genetics. Clinical review articles from expert authors are specifically devoted to the following: The Role of the Microbiome of o the Female Reproductive Tract on Health and Pregnancy; Eating Disorders and the Gut Microbiota; Maturation of the Infant Microbiome Community Structure and Function; Microbe-Host Interactions in Allergic Diseases; Emerging Role of the Gut Microbiota in Neurodevelopmental Disorders; Brain-Gut-Microbiota Axis and Mood Disorders; Brain-Gut-Microbiota and ADHD; The Microbiota-Gut-Brain Axis and Postpartum Depression; and The Microbiota and Pancreatic Cancer. Readers will come away with the latest information on the microbiome and how to incorporate the information into gut health for patients.
The Microbiome: Interactions with Organ Systems, Diet, and Genetics, an Issue of Gastroenterology Clinics of North America
Author: Rochellys Diaz Heijtz
Publisher: Elsevier
ISBN: 9780323679008
Category :
Languages : en
Pages :
Book Description
In consultation with Consulting Editor, Dr. Alan Buchman, Dr. Rocheyllys Diaz Heijtz has put together a state-of the-art issue of the Gastroenterology Clinics of North America devoted to The Microbiome: Interactions with Organ Systems, Diet, and Genetics. Clinical review articles from expert authors are specifically devoted to the following: The Role of the Microbiome of o the Female Reproductive Tract on Health and Pregnancy; Eating Disorders and the Gut Microbiota; Maturation of the Infant Microbiome Community Structure and Function; Microbe-Host Interactions in Allergic Diseases; Emerging Role of the Gut Microbiota in Neurodevelopmental Disorders; Brain-Gut-Microbiota Axis and Mood Disorders; Brain-Gut-Microbiota and ADHD; The Microbiota-Gut-Brain Axis and Postpartum Depression; and The Microbiota and Pancreatic Cancer. Readers will come away with the latest information on the microbiome and how to incorporate the information into gut health for patients.
Publisher: Elsevier
ISBN: 9780323679008
Category :
Languages : en
Pages :
Book Description
In consultation with Consulting Editor, Dr. Alan Buchman, Dr. Rocheyllys Diaz Heijtz has put together a state-of the-art issue of the Gastroenterology Clinics of North America devoted to The Microbiome: Interactions with Organ Systems, Diet, and Genetics. Clinical review articles from expert authors are specifically devoted to the following: The Role of the Microbiome of o the Female Reproductive Tract on Health and Pregnancy; Eating Disorders and the Gut Microbiota; Maturation of the Infant Microbiome Community Structure and Function; Microbe-Host Interactions in Allergic Diseases; Emerging Role of the Gut Microbiota in Neurodevelopmental Disorders; Brain-Gut-Microbiota Axis and Mood Disorders; Brain-Gut-Microbiota and ADHD; The Microbiota-Gut-Brain Axis and Postpartum Depression; and The Microbiota and Pancreatic Cancer. Readers will come away with the latest information on the microbiome and how to incorporate the information into gut health for patients.
Principles of Nutrigenetics and Nutrigenomics
Author: Raffaele De Caterina
Publisher: Academic Press
ISBN: 0128045876
Category : Medical
Languages : en
Pages : 588
Book Description
Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is the most comprehensive foundational text on the complex topics of nutrigenetics and nutrigenomics. Edited by three leaders in the field with contributions from the most well-cited researchers conducting groundbreaking research in the field, the book covers how the genetic makeup influences the response to foods and nutrients and how nutrients affect gene expression. Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is broken into four parts providing a valuable overview of genetics, nutrigenetics, and nutrigenomics, and a conclusion that helps to translate research into practice. With an overview of the background, evidence, challenges, and opportunities in the field, readers will come away with a strong understanding of how this new science is the frontier of medical nutrition. Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is a valuable reference for students and researchers studying nutrition, genetics, medicine, and related fields. - Uniquely foundational, comprehensive, and systematic approach with full evidence-based coverage of established and emerging topics in nutrigenetics and nutrigenomics - Includes a valuable guide to ethics for genetic testing for nutritional advice - Chapters include definitions, methods, summaries, figures, and tables to help students, researchers, and faculty grasp key concepts - Companion website includes slide decks, images, questions, and other teaching and learning aids designed to facilitate communication and comprehension of the content presented in the book
Publisher: Academic Press
ISBN: 0128045876
Category : Medical
Languages : en
Pages : 588
Book Description
Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is the most comprehensive foundational text on the complex topics of nutrigenetics and nutrigenomics. Edited by three leaders in the field with contributions from the most well-cited researchers conducting groundbreaking research in the field, the book covers how the genetic makeup influences the response to foods and nutrients and how nutrients affect gene expression. Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is broken into four parts providing a valuable overview of genetics, nutrigenetics, and nutrigenomics, and a conclusion that helps to translate research into practice. With an overview of the background, evidence, challenges, and opportunities in the field, readers will come away with a strong understanding of how this new science is the frontier of medical nutrition. Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is a valuable reference for students and researchers studying nutrition, genetics, medicine, and related fields. - Uniquely foundational, comprehensive, and systematic approach with full evidence-based coverage of established and emerging topics in nutrigenetics and nutrigenomics - Includes a valuable guide to ethics for genetic testing for nutritional advice - Chapters include definitions, methods, summaries, figures, and tables to help students, researchers, and faculty grasp key concepts - Companion website includes slide decks, images, questions, and other teaching and learning aids designed to facilitate communication and comprehension of the content presented in the book
Celiac Disease, An Issue of Gastroenterology Clinics of North America
Author: Peter H. R. Green
Publisher: Elsevier Health Sciences
ISBN: 0323655246
Category : Medical
Languages : en
Pages :
Book Description
Dr. Alan Buchman, Consulting Editor, selected world renown experts on celiac disease, Dr. Green and Dr. Lebwohl, to update the topic for gastroenterology readers. They have secured expert authors from top institutions to contribute articles with high clinical utility on the diagnosis, treatment, and management of celiac disease. These clinical reviews are devoted to the following topics: Clinical features and diagnosis of celiac disease; The gluten-free diet; Histopathology of celiac disease; Epidemiology and risk factors for celiac disease; Enteroscopy and capsule endoscopy in celiac disease; Measuring symptoms and other outcomes in celiac disease; Celiac disease in Asia; The microbiome and celiac disease; Follow-up of celiac disease; Refractory celiac disease; Non-dietary therapies for celiac disease; and Non-Celiac gluten or wheat sensitivity. Readers will come away with the most current clinical information they need to inform clinical decisions to improve patient outcomes.
Publisher: Elsevier Health Sciences
ISBN: 0323655246
Category : Medical
Languages : en
Pages :
Book Description
Dr. Alan Buchman, Consulting Editor, selected world renown experts on celiac disease, Dr. Green and Dr. Lebwohl, to update the topic for gastroenterology readers. They have secured expert authors from top institutions to contribute articles with high clinical utility on the diagnosis, treatment, and management of celiac disease. These clinical reviews are devoted to the following topics: Clinical features and diagnosis of celiac disease; The gluten-free diet; Histopathology of celiac disease; Epidemiology and risk factors for celiac disease; Enteroscopy and capsule endoscopy in celiac disease; Measuring symptoms and other outcomes in celiac disease; Celiac disease in Asia; The microbiome and celiac disease; Follow-up of celiac disease; Refractory celiac disease; Non-dietary therapies for celiac disease; and Non-Celiac gluten or wheat sensitivity. Readers will come away with the most current clinical information they need to inform clinical decisions to improve patient outcomes.
The Microbiota in Gastrointestinal Pathophysiology
Author: Martin H. Floch
Publisher: Academic Press
ISBN: 0128040629
Category : Science
Languages : en
Pages : 444
Book Description
The Microbiota in Gastrointestinal Pathophysiology: Implications for Human Health, Prebiotics, Probiotics and Dysbiosis is a one-stop reference on the state-of-the-art research on gut microbial ecology in relation to human disease. This important resource starts with an overview of the normal microbiota of the gastrointestinal tract, including the esophagus, stomach, Ileum, and colon. The book then identifies what a healthy vs. unhealthy microbial community looks like, including methods of identification. Also included is insight into which features and contributions the microbiota make that are essential and useful to host physiology, as is information on how to promote appropriate mutualisms and prevent undesirable dysbioses. Through the power of synthesizing what is known by experienced researchers in the field, current gaps are closed, raising understanding of the role of the microbiome and allowing for further research. - Explains how to modify the gut microbiota and how the current strategies used to do this produce their effects - Explores the gut microbiota as a therapeutic target - Provides the synthesis of existing data from both mainstream and non-mainstream sources through experienced researchers in the field - Serves as a 'one-stop' shop for a topic that's currently spread across a number of various journals
Publisher: Academic Press
ISBN: 0128040629
Category : Science
Languages : en
Pages : 444
Book Description
The Microbiota in Gastrointestinal Pathophysiology: Implications for Human Health, Prebiotics, Probiotics and Dysbiosis is a one-stop reference on the state-of-the-art research on gut microbial ecology in relation to human disease. This important resource starts with an overview of the normal microbiota of the gastrointestinal tract, including the esophagus, stomach, Ileum, and colon. The book then identifies what a healthy vs. unhealthy microbial community looks like, including methods of identification. Also included is insight into which features and contributions the microbiota make that are essential and useful to host physiology, as is information on how to promote appropriate mutualisms and prevent undesirable dysbioses. Through the power of synthesizing what is known by experienced researchers in the field, current gaps are closed, raising understanding of the role of the microbiome and allowing for further research. - Explains how to modify the gut microbiota and how the current strategies used to do this produce their effects - Explores the gut microbiota as a therapeutic target - Provides the synthesis of existing data from both mainstream and non-mainstream sources through experienced researchers in the field - Serves as a 'one-stop' shop for a topic that's currently spread across a number of various journals
The Gut Microbiome in Health and Disease
Author: Dirk Haller
Publisher: Springer
ISBN: 3319905457
Category : Medical
Languages : en
Pages : 355
Book Description
The book provides an overview on how the gut microbiome contributes to human health. The readers will get profound knowledge on the connection between intestinal microbiota and immune defense systems. The tools of choice to study the ecology of these highly-specialized microorganism communities such as high-throughput sequencing and metagenomic mining will be presented. In addition the most common diseases associated to the composition of the gut flora are discussed in detail. The book will address researchers, clinicians and advanced students working in biomedicine, microbiology and immunology.
Publisher: Springer
ISBN: 3319905457
Category : Medical
Languages : en
Pages : 355
Book Description
The book provides an overview on how the gut microbiome contributes to human health. The readers will get profound knowledge on the connection between intestinal microbiota and immune defense systems. The tools of choice to study the ecology of these highly-specialized microorganism communities such as high-throughput sequencing and metagenomic mining will be presented. In addition the most common diseases associated to the composition of the gut flora are discussed in detail. The book will address researchers, clinicians and advanced students working in biomedicine, microbiology and immunology.
Finding a Path to Safety in Food Allergy
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309450314
Category : Medical
Languages : en
Pages : 575
Book Description
Over the past 20 years, public concerns have grown in response to the apparent rising prevalence of food allergy and related atopic conditions, such as eczema. Although evidence on the true prevalence of food allergy is complicated by insufficient or inconsistent data and studies with variable methodologies, many health care experts who care for patients agree that a real increase in food allergy has occurred and that it is unlikely to be due simply to an increase in awareness and better tools for diagnosis. Many stakeholders are concerned about these increases, including the general public, policy makers, regulatory agencies, the food industry, scientists, clinicians, and especially families of children and young people suffering from food allergy. At the present time, however, despite a mounting body of data on the prevalence, health consequences, and associated costs of food allergy, this chronic disease has not garnered the level of societal attention that it warrants. Moreover, for patients and families at risk, recommendations and guidelines have not been clear about preventing exposure or the onset of reactions or for managing this disease. Finding a Path to Safety in Food Allergy examines critical issues related to food allergy, including the prevalence and severity of food allergy and its impact on affected individuals, families, and communities; and current understanding of food allergy as a disease, and in diagnostics, treatments, prevention, and public policy. This report seeks to: clarify the nature of the disease, its causes, and its current management; highlight gaps in knowledge; encourage the implementation of management tools at many levels and among many stakeholders; and delineate a roadmap to safety for those who have, or are at risk of developing, food allergy, as well as for others in society who are responsible for public health.
Publisher: National Academies Press
ISBN: 0309450314
Category : Medical
Languages : en
Pages : 575
Book Description
Over the past 20 years, public concerns have grown in response to the apparent rising prevalence of food allergy and related atopic conditions, such as eczema. Although evidence on the true prevalence of food allergy is complicated by insufficient or inconsistent data and studies with variable methodologies, many health care experts who care for patients agree that a real increase in food allergy has occurred and that it is unlikely to be due simply to an increase in awareness and better tools for diagnosis. Many stakeholders are concerned about these increases, including the general public, policy makers, regulatory agencies, the food industry, scientists, clinicians, and especially families of children and young people suffering from food allergy. At the present time, however, despite a mounting body of data on the prevalence, health consequences, and associated costs of food allergy, this chronic disease has not garnered the level of societal attention that it warrants. Moreover, for patients and families at risk, recommendations and guidelines have not been clear about preventing exposure or the onset of reactions or for managing this disease. Finding a Path to Safety in Food Allergy examines critical issues related to food allergy, including the prevalence and severity of food allergy and its impact on affected individuals, families, and communities; and current understanding of food allergy as a disease, and in diagnostics, treatments, prevention, and public policy. This report seeks to: clarify the nature of the disease, its causes, and its current management; highlight gaps in knowledge; encourage the implementation of management tools at many levels and among many stakeholders; and delineate a roadmap to safety for those who have, or are at risk of developing, food allergy, as well as for others in society who are responsible for public health.
Pediatric Nutrition in Practice
Author: B. Koletzko
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318026913
Category : Medical
Languages : en
Pages : 349
Book Description
There is no other time in life when the provision of adequate and balanced nutrition is of greater importance than during infancy and childhood. During this dynamic phase characterized by rapid growth, development and developmental plasticity, a sufficient amount and appropriate composition of nutrients both in health and disease are of key importance for growth, functional outcomes such as cognition and immune response, and the metabolic programming of long-term health and well-being. This compact reference text provides concise information to readers who seek quick guidance on practical issues in the nutrition of infants, children and adolescents. After the success of the first edition, which sold more than 50'000 copies in several languages, the editors prepared this thoroughly revised and updated second edition which focuses again on nutritional challenges in both affluent and poor populations around the world. Serving as a practical reference guide, this book will contribute to further improving the quality of feeding of healthy infants and children, as well as enhancing the standards of nutritional care in sick children.
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318026913
Category : Medical
Languages : en
Pages : 349
Book Description
There is no other time in life when the provision of adequate and balanced nutrition is of greater importance than during infancy and childhood. During this dynamic phase characterized by rapid growth, development and developmental plasticity, a sufficient amount and appropriate composition of nutrients both in health and disease are of key importance for growth, functional outcomes such as cognition and immune response, and the metabolic programming of long-term health and well-being. This compact reference text provides concise information to readers who seek quick guidance on practical issues in the nutrition of infants, children and adolescents. After the success of the first edition, which sold more than 50'000 copies in several languages, the editors prepared this thoroughly revised and updated second edition which focuses again on nutritional challenges in both affluent and poor populations around the world. Serving as a practical reference guide, this book will contribute to further improving the quality of feeding of healthy infants and children, as well as enhancing the standards of nutritional care in sick children.
Ending the War Metaphor
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309180120
Category : Medical
Languages : en
Pages : 306
Book Description
Infectious diseases have existed longer than us, as long as us, or are relatively newer than us. It may be the case that a disease has existed for many, many years but has only recently begun affecting humans. At the turn of the century the number of deaths caused by infections in the United States had been falling steadily but since the '80s has seen an increase. In the past 30 years alone 37 new pathogens have been identified as human disease threats and 12% of known human pathogens have been classified as either emerging or remerging. Whatever the story, there is currently a "war" on infectious diseases. This war is simply the systematic search for the microbial "cause" of each disease, followed by the development of antimicrobial therapies. The "war" on infectious diseases, however, must be revisited in order to develop a more realistic and detailed picture of the dynamic interactions among and between host organisms and their diverse populations of microbes. Only a fraction of these microbes are pathogens. Thus, in order to explore the crafting of a new metaphor for host-microbe relationships, and to consider how such a new perspective might inform and prioritize biomedical research, the Forum on Microbial Threats of the Institute of Medicine (IOM) convened the workshop, Ending the War Metaphor: The Changing Agenda for Unraveling the Host-Microbe Relationship on March 16-17, 2005. Workshop participants examined knowledge and approaches to learning about the bacterial inhabitants of the human gut, the best known host-microbe system, as well as findings from studies of microbial communities associated with other mammals, fish, plants, soil, and insects. The perspective adopted by this workshop is one that recognizes the breadth and diversity of host-microbe relationships beyond those relative few that result in overt disease. Included in this summary are the reports and papers of individuals participating in the Forum as well as the views of the editors.
Publisher: National Academies Press
ISBN: 0309180120
Category : Medical
Languages : en
Pages : 306
Book Description
Infectious diseases have existed longer than us, as long as us, or are relatively newer than us. It may be the case that a disease has existed for many, many years but has only recently begun affecting humans. At the turn of the century the number of deaths caused by infections in the United States had been falling steadily but since the '80s has seen an increase. In the past 30 years alone 37 new pathogens have been identified as human disease threats and 12% of known human pathogens have been classified as either emerging or remerging. Whatever the story, there is currently a "war" on infectious diseases. This war is simply the systematic search for the microbial "cause" of each disease, followed by the development of antimicrobial therapies. The "war" on infectious diseases, however, must be revisited in order to develop a more realistic and detailed picture of the dynamic interactions among and between host organisms and their diverse populations of microbes. Only a fraction of these microbes are pathogens. Thus, in order to explore the crafting of a new metaphor for host-microbe relationships, and to consider how such a new perspective might inform and prioritize biomedical research, the Forum on Microbial Threats of the Institute of Medicine (IOM) convened the workshop, Ending the War Metaphor: The Changing Agenda for Unraveling the Host-Microbe Relationship on March 16-17, 2005. Workshop participants examined knowledge and approaches to learning about the bacterial inhabitants of the human gut, the best known host-microbe system, as well as findings from studies of microbial communities associated with other mammals, fish, plants, soil, and insects. The perspective adopted by this workshop is one that recognizes the breadth and diversity of host-microbe relationships beyond those relative few that result in overt disease. Included in this summary are the reports and papers of individuals participating in the Forum as well as the views of the editors.
Microbiome in Human Health and Disease
Author: Pallaval Veera Bramhachari
Publisher: Springer Nature
ISBN: 9811631565
Category : Medical
Languages : en
Pages : 306
Book Description
The book provides an overview on how the microbiome contributes to human health and disease. The microbiome has also become a burgeoning field of research in medicine, agriculture & environment. The readers will obtain profound knowledge on the connection between intestinal microbiota and immune defense systems, medicine, agriculture & environment. The book may address several researchers, clinicians and scholars working in biomedicine, microbiology and immunology. The application of new technologies has no doubt revolutionized the research initiatives providing new insights into the dynamics of these complex microbial communities and their role in medicine, agriculture & environment shall be more emphasized. Drawing on broad range concepts of disciplines and model systems, this book primarily provides a conceptual framework for understanding these human-microbe, animal-microbe & plant-microbe, interactions while shedding critical light on the scientific challenges that lie ahead. Furthermore this book explains why microbiome research demands a creative and interdisciplinary thinking—the capacity to combine microbiology with human, animal and plant physiology, ecological theory with immunology, and evolutionary perspectives with metabolic science.This book provides an accessible and authoritative guide to the fundamental principles of microbiome science, an exciting and fast-emerging new discipline that is reshaping many aspects of the life sciences. These microbial partners can also drive ecologically important traits, from thermal tolerance to diet in a typical immune system, and have contributed to animal and plant diversification over long evolutionary timescales. Also this book explains why microbiome research presents a more complete picture of the biology of humans and other animals, and how it can deliver novel therapies for human health and new strategies.
Publisher: Springer Nature
ISBN: 9811631565
Category : Medical
Languages : en
Pages : 306
Book Description
The book provides an overview on how the microbiome contributes to human health and disease. The microbiome has also become a burgeoning field of research in medicine, agriculture & environment. The readers will obtain profound knowledge on the connection between intestinal microbiota and immune defense systems, medicine, agriculture & environment. The book may address several researchers, clinicians and scholars working in biomedicine, microbiology and immunology. The application of new technologies has no doubt revolutionized the research initiatives providing new insights into the dynamics of these complex microbial communities and their role in medicine, agriculture & environment shall be more emphasized. Drawing on broad range concepts of disciplines and model systems, this book primarily provides a conceptual framework for understanding these human-microbe, animal-microbe & plant-microbe, interactions while shedding critical light on the scientific challenges that lie ahead. Furthermore this book explains why microbiome research demands a creative and interdisciplinary thinking—the capacity to combine microbiology with human, animal and plant physiology, ecological theory with immunology, and evolutionary perspectives with metabolic science.This book provides an accessible and authoritative guide to the fundamental principles of microbiome science, an exciting and fast-emerging new discipline that is reshaping many aspects of the life sciences. These microbial partners can also drive ecologically important traits, from thermal tolerance to diet in a typical immune system, and have contributed to animal and plant diversification over long evolutionary timescales. Also this book explains why microbiome research presents a more complete picture of the biology of humans and other animals, and how it can deliver novel therapies for human health and new strategies.