The Logic of Omeprazole PDF Download

Author: Irvin M. Modlin
Publisher:
ISBN: 9780943035000
Category : Science
Languages : en
Pages : 152

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Author: Jie Jack Li
Publisher: Oxford University Press
ISBN: 0199737681
Category : Business & Economics
Languages : en
Pages : 238

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"This book uses the cases of several landmark drugs to discuss the history of the pharmaceutical industry, and discusses what could be next"--Provided by publisher.

Author: Philip Katz
Publisher: CRC Press
ISBN: 1040135692
Category : Medical
Languages : en
Pages : 200

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Are you looking for concise, practical answers to questions that are often left unanswered by traditional GERD references? Are you seeking brief, evidence-based advice for complicated cases or complications? Curbside Consultation in GERD: 49 Clinical Questions provides quick and direct answers to the thorny questions commonly posed during a “curbside consultation” between colleagues. Dr. Philip Katz has designed this unique reference, which offers expert advice, preferences, and opinions on tough clinical questions commonly associated with GERD. The unique Q&A format provides quick access to current information related to GERD with the simplicity of a conversation between two colleagues. Numerous images, diagrams, and references are included to enhance the text and to illustrate the treatment of GERD patients. Curbside Consultation in GERD: 49 Clinical Questions provides information basic enough for residents while also incorporating expert advice that even high-volume clinicians will appreciate. Gastroenterologists, fellows and residents in training, surgical attendings, and surgical residents will benefit from the user-friendly and casual format and the expert advice contained within. Some of the questions that are answered: Can medical therapy alter the natural history of Barrett’s esophagus? Can antireflux surgery alter the natural history of Barrett’s esophagus? How does pregnancy affect GERD? Is GERD in pregnancy a risk for long-term reflux? What is the association of obesity and GERD? What are the so-called extraesophageal manifestations of GERD? Is there a gender difference in reflux disease? Does this affect treatment?

Author: Shawna L. Fleming
Publisher: Infobase Publishing
ISBN: 1438101449
Category : Medical
Languages : en
Pages : 142

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Describes the symptoms and effects of helicobacter pylori infections--the leading cause of stomach ulcers--the role of the bacteria in harboring other diseases, how they affect digestion, and treatment options.

Author: Jie Jack Li
Publisher: Oxford University Press
ISBN: 0199362602
Category : Medical
Languages : en
Pages : 219

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Drugs like Lipitor, Plavix, Taxol, and Zoloft are integral in today's medicinal world. These widely used products save lives and improve the quality of lives, playing a crucial role in everything from cholesterol management to cancer treatment. These advances in medicine were brought into existence after nuanced process of creation, featuring a wide range of chemical and pharmacological experimentation and discovery. Top Drugs: Their History, Pharmacology, and Synthesis provides an in-depth study on ten prominent drugs, outlining the chemistry behind each one's creation. Jie Jack Li, a medicinal chemist and an expert on drug discovery, offers a thorough analysis of the landscape of current drug development. The comprehensive text is divided by health issues, including cardiovascular, cancer, metabolic diseases, and infectious diseases. Each section features individual chapters on significant drugs, outlining the chemistry and history of the drug's discovery. Li begins each chapter with the product's history, providing necessary context. Li then proceeds to describe the mechanism of action, structure-activity relationship (SAR), bioavailability, metabolism, toxicology, the discovery route, and the process route. Top Drugs: Their History, Pharmacology, and Synthesis will acclimate students, scientists, and interested laypersons to the world of chemistry and drug discovery.

Author: Theodore M. Bayless
Publisher: PMPH-USA
ISBN: 9781550092486
Category : CD-ROMs
Languages : en
Pages : 892

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The main emphasis of this new fifth edition ofAdvanced Therapy of Gastroenterology and Liver Diseaseis on patient management. Chapters are dedicated to general topics in gastroenterology and hepatology practice and the use of diagnostic tests in clinical decision-making. Principles in endoscopy including sedation and infection control are also examined. Each chapter consists of recommendations from an expert in the field concerning a very focused problem. The authors discuss recommendations for instituting, modifying and monitoring therapy, including combinations of drugs and / or therapeutic and diagnostic procedures.

Author: C. Scarpignato
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805576587
Category : Medical
Languages : en
Pages : 481

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Author: Arthur J. Atkinson Jr.
Publisher: Elsevier
ISBN: 0080466427
Category : Science
Languages : en
Pages : 567

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This revised second edition covers the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development, focusing on the fundamentals that underlie the clinical use and contemporary development of pharmaceuticals. Authors drawn from academia, the pharmaceutical industry and government agencies cover the spectrum of material, including pharmacokinetic practice questions, covered by the basic science section of the certifying examination offered by the American Board of Clinical Pharmacology. This unique reference is recommended by the Board as a study text and includes modules on drug discovery and development to assist students as well as practicing pharmacologists. Unique breadth of coverage ranging from drug discovery and development to individualization and quality assessment of drug therapy Unusual cohesive of presentation that stems from author participation in an ongoing popular NIH course Instructive linkage of pharmacokinetic theory and applications with provision of sample problems for self-study Wide-ranging perspective of authors drawn from the ranks of Federal agencies, academia and the pharmaceutical industry Expanded coverage of pharmacogenetics Expanded coverage of drug transporters and their role in interactions Inclusion of new material on enzyme induction mechanisms in chapters on drug metabolism and drug interactions A new chapter on drug discovery that focuses on oncologic agents Inclusion of therapeutic antibodies in chapter on biotechnology products

Author: Martie Whittekin
Publisher: Square One Publishers, Inc.
ISBN: 075705210X
Category : Health & Fitness
Languages : en
Pages : 169

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Written by health professionals who are well recognized in their respective fields, these concise, easy-to-read books focus on a wide range of important health concerns. From migraine headaches to high cholesterol, each title looks at a specific problem; each provides a clear explanation of the disorder, its causes, and its symptoms; and each offers natural solutions that can either greatly reduce or completely eliminate the problem. Some titles also focus on natural alternatives to drugs with serious side effects—alternatives that in many cases can be used in conjunction with prescription medications. This growing series of titles can be counted on to provide safe and sensible solutions to all-too-common health problems.

Author: Lars Olbe
Publisher: Birkhäuser
ISBN: 3034887957
Category : Medical
Languages : en
Pages : 245

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Book Description
Inhibition of the proton pump in the parietal cells has been established as the main therapeutic principle in the treatment of acid-related diseases, such as peptic ulcer and gastro-oesophageal reflux. The proton pump inhi bitors are tailored for their purpose. They accumulate in the target cell, are activated by acid and bind strongly to the specific target - the proton pump. The clinical superiority of the proton pump inhibitors is due not only to their high efficacy but also to the long duration of the acid inhibition in comparison with other antisecretory drugs. At present when drug discovery mostly relies on identification and characterization of potential targets by genome research, molecular biology, combinatorial chemistry and automated screening, it seems worthwhile to present the development of the tITst proton pump inhibitor - omeprazol- starting from a chemical structure with an observed antisecretory effect but also severe toxic effects that had to be eliminated. As always, basic and applied research operate luind in hand to optimize the delicate balance be tween efficacy and safety of a new drug. This goal often involves time and many different specialists.