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Author: Mircea Steriade Publisher: ISBN: 9780262284318 Category : Medical Languages : en Pages : 366
Book Description
Connecting in vitro and in vivo studies of the mammalian brain. In this book Mircea Steriade cautions against the tendency of some neuroscientists to infer global brain functions such as arousal and sleep, epileptic events, and even conscious thinking from the properties of single cells. Based on his lifetime of research on intact brains, Steriade emphasizes the need to understand isolated networks within the context of the whole mammalian brain and to understand the brain of a behaving animal in terms of its fully dissected circuits. As much as knowledge of brain anatomy and function has progressed, Steriade is highly skeptical about the quest to relate consciousness to specific neuronal types. The book's sections are Changing Concepts of Localization of Brain Function, Evolution of Methods in Brain Studies, Similar and Contrasting Results from Studies in the Intact and Sliced Brain, Building Blocks of Synaptic Networks Underlying Normal and Paroxysmal States, and Of Neurons and Consciousness.
Author: Mircea Steriade Publisher: ISBN: 9780262284318 Category : Medical Languages : en Pages : 366
Book Description
Connecting in vitro and in vivo studies of the mammalian brain. In this book Mircea Steriade cautions against the tendency of some neuroscientists to infer global brain functions such as arousal and sleep, epileptic events, and even conscious thinking from the properties of single cells. Based on his lifetime of research on intact brains, Steriade emphasizes the need to understand isolated networks within the context of the whole mammalian brain and to understand the brain of a behaving animal in terms of its fully dissected circuits. As much as knowledge of brain anatomy and function has progressed, Steriade is highly skeptical about the quest to relate consciousness to specific neuronal types. The book's sections are Changing Concepts of Localization of Brain Function, Evolution of Methods in Brain Studies, Similar and Contrasting Results from Studies in the Intact and Sliced Brain, Building Blocks of Synaptic Networks Underlying Normal and Paroxysmal States, and Of Neurons and Consciousness.
Author: Raymond Dingledine Publisher: Springer Science & Business Media ISBN: 1468445839 Category : Medical Languages : en Pages : 452
Book Description
In little less than a decade brain slices have gained prominence among neurobiologists as appropriate tools to study cellular electrophysiolog ical aspects of mammalian brain function. The purpose of this volume is to present in some detail several inquiries in the brain sciences that have benefited greatly by the use of brain slices. The book is directed primarily toward advanced students and researchers wishing to evaluate the impact these in vitro preparations of the mammalian brain are having on neurobiology. The term brain slice has come to refer to thin (100-700 j. Lm) sections of a brain region prepared from adult mammals and maintained for many hours in vitro, for either electrophysiological or biochemical stud ies. In addition to good accessibility, slices feature relatively intact syn aptic connections that allow a variety of experiments not feasible with standard in vivo or tissue culture preparations. Certain electrophysiol ogical studies once practical only with invertebrate models are becoming routine with mammalian brain slices. The ability to perform both bio chemical and electro physiological experiments on the same piece of CNS tissue provides additional bright prospects for future research. Although most of the electrophysiological studies have dealt with hippocampal slices, it should be evident from this book that slice methodology is not limited to the hippocampus. The Appendix, "Brain Slice Methods," is a multiauthored treatment of the technical aspects of brain slice work, collected into one document.
Author: Avital Schurr Publisher: CRC Press ISBN: 1000714357 Category : Medical Languages : en Pages : 352
Book Description
Brain Slices in Basic and Clinical Research describes advancements in the field of brain function and dysfunction through use of central nervous system slice preparations. Topics are authored by leading scientists and include the following: Mechanisms of synaptic plasticity as the basis of memory processes Chaos and synaptic variability Brain calcium currents Glutamate receptors Pathophysiology of excitotoxins Cerebral hypoxia-ischemia Neuronal injury Free radicals Optical methods of measuring brain metabolism Voltammetry in brain slices Calcium imaging Patch-clamp recording and application of macromolecules through patch-clamp pipettes in brain slices Intracellular double labeling of various neuronal populations Use of brain slices in teaching neurophysiological methods Most of the topics are published in book format for the first time, and some of the techniques are more fully detailed than in any other book.
Author: Marc D. Binder Publisher: Springer ISBN: 9783540237358 Category : Medical Languages : en Pages : 4398
Book Description
This 5000-page masterwork is literally the last word on the topic and will be an essential resource for many. Unique in its breadth and detail, this encyclopedia offers a comprehensive and highly readable guide to a complex and fast-expanding field. The five-volume reference work gathers more than 10,000 entries, including in-depth essays by internationally known experts, and short keynotes explaining essential terms and phrases. In addition, expert editors contribute detailed introductory chapters to each of 43 topic fields ranging from the fundamentals of neuroscience to fascinating developments in the new, inter-disciplinary fields of Computational Neuroscience and Neurophilosophy. Some 1,000 multi-color illustrations enhance and expand the writings.
Author: Suzana Herculano-Houzel Publisher: MIT Press ISBN: 0262333201 Category : Science Languages : en Pages : 271
Book Description
Why our human brains are awesome, and how we left our cousins, the great apes, behind: a tale of neurons and calories, and cooking. Humans are awesome. Our brains are gigantic, seven times larger than they should be for the size of our bodies. The human brain uses 25% of all the energy the body requires each day. And it became enormous in a very short amount of time in evolution, allowing us to leave our cousins, the great apes, behind. So the human brain is special, right? Wrong, according to Suzana Herculano-Houzel. Humans have developed cognitive abilities that outstrip those of all other animals, but not because we are evolutionary outliers. The human brain was not singled out to become amazing in its own exclusive way, and it never stopped being a primate brain. If we are not an exception to the rules of evolution, then what is the source of the human advantage? Herculano-Houzel shows that it is not the size of our brain that matters but the fact that we have more neurons in the cerebral cortex than any other animal, thanks to our ancestors' invention, some 1.5 million years ago, of a more efficient way to obtain calories: cooking. Because we are primates, ingesting more calories in less time made possible the rapid acquisition of a huge number of neurons in the still fairly small cerebral cortex—the part of the brain responsible for finding patterns, reasoning, developing technology, and passing it on through culture. Herculano-Houzel shows us how she came to these conclusions—making “brain soup” to determine the number of neurons in the brain, for example, and bringing animal brains in a suitcase through customs. The Human Advantage is an engaging and original look at how we became remarkable without ever being special.
Author: Publisher: Elsevier ISBN: 0444636420 Category : Medical Languages : en Pages : 448
Book Description
Brain Banking, Volume 150, serves as the only book on the market offering comprehensive coverage of the functional realities of brain banking. It focuses on brain donor recruitment strategies, brain bank networks, ethical issues, brain dissection/tissue processing/tissue dissemination, neuropathological diagnosis, brain donor data, and techniques in brain tissue analysis. In accordance with massive initiatives, such as BRAIN and the EU Human Brain Project, abnormalities and potential therapeutic targets of neurological and psychiatric disorders need to be validated in human brain tissue, thus requiring substantial numbers of well characterized human brains of high tissue quality with neurological and psychiatric diseases. Offers comprehensive coverage of the functional realities of brain banking, with a focus on brain donor recruitment strategies, brain bank networks, ethical issues, and more Serves as a valuable resource for staff in existing brain banks by highlighting best practices Enhances the sharing of expertise between existing banks and highlights a range of techniques applicable to banked tissue for neuroscience researchers Authored by leaders from brain banks around the globe – the broadest, most expert coverage available
Author: Chace Calum Publisher: Three CS ISBN: 9780993211607 Category : Fiction Languages : en Pages : 412
Book Description
Pandora's Brain Description Around half the scientists researching artificial intelligence (AI) think that a conscious machine with cognitive abilities at or beyond human level will be created by 2050. If they are right, the consequence could be an intelligence explosion, in which the AI rapidly and enormously exceeds human competence. Pandora's Brain is a science thriller by best-selling writer Calum Chace. It uses the issues raised by the possible coming machine intelligence explosion as a platform for a fast-paced and thought-provoking adventure story. The story is set in the very near future, and features Matt, a shy but engaging and resourceful student who discovers that his recently-deceased father was involved in research that could enable the construction of the world's first conscious machine. Matt's enquiries lead to him being kidnapped, as he is caught in the crossfire between two groups pursuing that goal - one led by a Russian billionaire, and another backed by the US military. Matt has to do more than simply survive: he has to harness these powerful forces to his own ends. At stake is his own life and those of his family and friends. A dramatic seaborne rescue operation, a series of brutal murders and other filmic action scenes follow. In the course of his adventures, Matt discovers that the potential upside of creating machine intelligence includes immortality, and godlike powers of understanding and being - but the potential downside is immediate extinction, or worse. As he is drawn deeper into his adventure, he becomes both the symbol and the victim of a global struggle over the approach to be taken towards this powerful new technology. A landmark decision at a meeting of the UN General Assembly forces Matt to make a fateful decision which sparks the story's final twist. Selected reviews for Pandora's Brain: I love the concepts in this book! Peter James, author of the best-selling Roy Grace series Awesome! Count me as a fan. Brad Feld, co-founder of Techstars Pandora s Brain is a captivating tale of developments in artificial intelligence that could, conceivably, be just around the corner. Mainly set in the present day, the plot unfolds in an environment that seems reassuringly familiar, but which is overshadowed by a combination of both menace and promise. Carefully crafted, and absorbing from its very start, the book held my rapt attention throughout a series of surprise twists, as various personalities react in different ways to a growing awareness of that menace and promise. David Wood, Chairman of London Futurists I was eagerly anticipating a fiction adventure book on precisely this topic! Very well done, Calum Chace. A timely, suspenseful, and balanced portrayal of AI and the most important decisions humanity will make in the near future. Hank Pellissier, producer of the Transhuman Visions conferences Pandora s Brain is a tour de force that neatly explains the key concepts behind the likely future of artificial intelligence in the context of a thriller novel. Ambitious and well executed, it will appeal to a broad range of readers. In the same way that Suarez s Daemon and Naam s Nexus leaped onto the scene, redefining what it meant to write about technology, Pandora s Brain will do the same for artificial intelligence. "Mind uploading? Check. Human equivalent AI? Check. Hard takeoff singularity? Check. Strap in, this is one heck of a ride. William Hertling, author of the Singularity series of novels "
Author: Mircea Steriade
Author: Mircea Steriade
Author: Mircea Steriade
Author: Raymond Dingledine
Author: 
Author: Avital Schurr
Author: Avital Schurr
Author: Marc D. Binder
Author: Suzana Herculano-Houzel
Author: 
Author: Chace Calum