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Author: Yousef Al-Dashti Publisher: ISBN: 9780438930841 Category : Languages : en Pages :
Book Description
Burdens of aging associated with chronic non-communicable and other age-related diseases may to a significant extent be preventable with lifestyle modification, including diet. The overall aim of this dissertation was to examine the role of select bioactive dietary components, identified as any foods, dietary extracts, nutrients, or non-nutrient constituents, in improving the prognosis in cases of select age-related diseases, in part, via clinical research conducted in partial satisfaction of the requirements for the degree. Specifically, dried plums and other phenolic-rich dietary components were investigated to determine their effects on various indicators of cardiovascular and bone health in populations at risk. Diets rich in plant-derived foods and components have been reported to reduce the risk of both CVD and osteoporosis. Current evidence from epidemiological and clinical trials, including data from this dissertation, indicate that certain plant-derived dietary components including bioactive single nutrients and non-nutrient compounds (e.g., polyphenols), whole foods (e.g., dried plums, cocoa), dietary extracts (e.g., derived from lychee fruit and grape seeds) can favorably modulate markers of cardiovascular health such as vascular function, blood pressure, lipid profiles, platelet activity, circulating angiogenic cells, and inflammatory and oxidant defense pathways. Similarly, certain of these dietary components can provide bone health benefits through modulation of bone mineral density and several associated blood biomarkers. Relevant mechanisms of action related to these certain dietary components, as well as major questions and gaps in research are presented and discussed. Prevention of age-related CVD and osteoporosis may benefit from careful attention to nutritional adequacy and a diet tailored to positively optimize an individual’s health state, which can be accomplished through the incorporation of nutrition evaluations and services into preventative care. Collectively, data from this dissertation suggests that incorporating certain isolated well-characterized bioactive compounds, whole foods, and extracts into an effective overall diet pattern, based on current key dietary recommendations, can improve cardiovascular and bone health, particularly in individuals who are at risk.
Author: Yousef Al-Dashti Publisher: ISBN: 9780438930841 Category : Languages : en Pages :
Book Description
Burdens of aging associated with chronic non-communicable and other age-related diseases may to a significant extent be preventable with lifestyle modification, including diet. The overall aim of this dissertation was to examine the role of select bioactive dietary components, identified as any foods, dietary extracts, nutrients, or non-nutrient constituents, in improving the prognosis in cases of select age-related diseases, in part, via clinical research conducted in partial satisfaction of the requirements for the degree. Specifically, dried plums and other phenolic-rich dietary components were investigated to determine their effects on various indicators of cardiovascular and bone health in populations at risk. Diets rich in plant-derived foods and components have been reported to reduce the risk of both CVD and osteoporosis. Current evidence from epidemiological and clinical trials, including data from this dissertation, indicate that certain plant-derived dietary components including bioactive single nutrients and non-nutrient compounds (e.g., polyphenols), whole foods (e.g., dried plums, cocoa), dietary extracts (e.g., derived from lychee fruit and grape seeds) can favorably modulate markers of cardiovascular health such as vascular function, blood pressure, lipid profiles, platelet activity, circulating angiogenic cells, and inflammatory and oxidant defense pathways. Similarly, certain of these dietary components can provide bone health benefits through modulation of bone mineral density and several associated blood biomarkers. Relevant mechanisms of action related to these certain dietary components, as well as major questions and gaps in research are presented and discussed. Prevention of age-related CVD and osteoporosis may benefit from careful attention to nutritional adequacy and a diet tailored to positively optimize an individual’s health state, which can be accomplished through the incorporation of nutrition evaluations and services into preventative care. Collectively, data from this dissertation suggests that incorporating certain isolated well-characterized bioactive compounds, whole foods, and extracts into an effective overall diet pattern, based on current key dietary recommendations, can improve cardiovascular and bone health, particularly in individuals who are at risk.
Author: Cinthia Bau Betim Cazarin Publisher: Academic Press ISBN: 0128225904 Category : Technology & Engineering Languages : en Pages : 257
Book Description
Bioactive Food Components Activity in Mechanistic Approach presents the role of functional foods and bioactive compounds in inflammation. This book focuses on bioactive compounds, including phenolics, prebiotics, carotenoids, tocopherols, bioactive peptides, probiotics, polyunsaturated and monounsaturated fatty acids, and describes their actions in several diseases, mainly obesity and co-morbidities, inflammatory bowel disease, cognitive decline and cancer, and aging. Intended for food, nutrition, and nutraceutical researchers, as well as those studying related fields, the book offers a mechanistic approach that is currently lacking in the market. Explores the mechanistic approach of functional foods in health and disease Contains definitions, case studies, applications, literature reviews, recent developments and text boxes Provides coverage of phenolic compounds, prebiotics and probiotics, carotenoids, tocopherols, bioactive peptides, polyunsaturated and monounsaturated fatty acids, and sulfur compounds
Author: Ronald Ross Watson Publisher: Academic Press ISBN: 0123971551 Category : Health & Fitness Languages : en Pages : 516
Book Description
Bioactive Food as Dietary Interventions for the Aging Population presents scientific evidence of the impact bioactive foods can have in the prevention and mediation of age related diseases. Documents foods that can affect metabolic syndrome and ways the associated information could be used to understand other diseases, which share common etiological pathways.
Author: Donato F. Romagnolo Publisher: Humana Press ISBN: 3319279696 Category : Medical Languages : en Pages : 346
Book Description
This text is an especially timely new text as the number of studies focusing on the impact of the Mediterranean diet on disease prevention increases every year. The fundamental question addressed in this text is how food components and behavior of the Mediterranean diet reduce the risk of chronic diseases. In-depth chapters provide an overview of preclinical and clinical studies on Mediterranean dietary patterns, food components and lifestyle and their impact on health and disease. Large-scale “omic” approaches are highlighted to educate the reader about the molecular mechanisms through which specific components of the Mediterranean diet improves health and the opportunities and challenges for translating into practice the food recommendations of the Mediterranean pyramid. The volume concludes with information about the nutritional adequacy of Mediterranean foods and provides selected recipes. Mediterranean Diet: Impact on Health and Disease will be of great interest to students, clinicians, and scientists engaged in promoting health through nutrition and physical activity.
Author: Blanca Hernandez-Ledesma Publisher: Academic Press ISBN: 012822584X Category : Technology & Engineering Languages : en Pages : 676
Book Description
Current Advances for Development of Functional Foods Modulating Inflammation and Oxidative Stress presents the nutritional and technological aspects related to the development of functional foods with anti-inflammatory and antioxidant effects. Specifically, analytical approaches for the characterization of anti-inflammatory and antioxidant properties of healthy foods and functional constituents, as well as technological strategies for the extraction of compounds and fractions from raw materials to produce anti-inflammatory and antioxidant ingredients are addressed. In addition, the molecular mechanisms by which foods and their components can modulate inflammation and their oxidative stress effects on disease prevention are explored. Finally, clinical research addressing nutritional needs in pathological subjects with inflammatory diseases are considered. Covers methods of analysis and extraction of anti-inflammatory and antioxidant compounds Offers an overview of the main anti-inflammatory and antioxidant compounds in foods Provides a guide on the mechanisms of action and health benefits of anti-inflammatory and antioxidant dietary bioactives
Author: María Chávarri Hueda Publisher: BoD – Books on Demand ISBN: 9535134396 Category : Science Languages : en Pages : 320
Book Description
In recent years, the concern of society about how food influences the health status of people has increased. Consumers are increasingly aware that food can prevent the development of certain diseases, so in recent years, the food industry is developing new, healthier products taking into account aspects such as trans fats, lower caloric intake, less salt, etc. However, there are bioactive compounds that can improve the beneficial effect of these foods and go beyond the nutritional value. This book provides information on impact of bioactive ingredients (vitamins, antioxidants, compounds of the pulses, etc.) on nutrition through food, how functional foods can prevent disease, and tools to evaluate the effects of bioactive ingredients, functional foods, and diet.
Author: Dragana Djurica Publisher: ISBN: 9781339064413 Category : Languages : en Pages :
Book Description
While cardiovascular health claims are commonly made for diverse foods and supplements, in many cases the evidence supporting the claims is limited. The overall aim of this dissertation was to examine the effects of isolated bioactive compounds from foods and whole foods on select indicators of vascular health in populations at high risk for cardiovascular disease. Four independent projects were completed. The first study examined the effects of three different dietary intakes of a lychee fruit extract for two weeks on microvascular function, platelet function and blood lipids in a population of postmenopausal women. No significant changes in these selected markers of vascular health were detected. The second project examined the effects of walnuts on microvascular function, platelet function and blood lipids in a population of hypercholesterolemic postmenopausal women. Significant positive changes in microvascular function were documented in the walnut group compared to the control group after daily walnut intake for four weeks. The third project examined acute effects of two forms of resveratrol on microvascular function and platelet function, as well as on plasma concentrations of resveratrol, in postmenopausal women. Significant improvements in microvascular function were noted with a resveratrol-arginine complex, but not with trans-resveratrol. Plasma resveratrol concentrations significantly increased with both resveratrol supplements; however, a significant positive correlation between plasma resveratrol and microvascular function was only noted with resveratrol-arginine complex. Additionally, a significant decrease in arachidonic acid induced platelet aggregation was noted with resveratrol-arginine complex. The fourth project was a study that assessed changes in microvascular function, plasma nitrate/nitrite levels, circulating progenitor cells and platelet reactivity in overweight or obese adolescent males in response to the acute and short term consumption of a freeze-dried strawberry powder. The major findings from this study include a significant increase in microvascular function acutely after a week of daily consumption of strawberry powder, an increase in plasma nitrate/nitrite acutely and short term, as well as an increase in HDL after seven days of strawberry supplementation. These studies collectively suggest that incorporating isolated well-characterized bioactive compounds, as well as select whole foods into a daily diet can improve vascular health in individuals who are at risk for cardiovascular disease. The results also support the concept that with respect to select indicators of vascular health (e.g. platelet reactivity, endothelial relaxation, etc.), a preliminary testing of the putative beneficial effects of foods and supplements can be of value in the identification of promising foods and food components.
Author: Sang-Woon Choi Publisher: CRC Press ISBN: 1420063561 Category : Medical Languages : en Pages : 258
Book Description
Explores the Newly Discovered Link Between Nutrition and EpigeneticsCurrent research suggests that nutrients are more than just food components and that certain nutrients can impact the expression of genes that lead to the development of chronic diseases. With contributions from experts in both fields, Nutrients and Epigenetics examines the epigene
Author: Institute of Medicine Publisher: National Academies Press ISBN: 0309158834 Category : Medical Languages : en Pages : 192
Book Description
Does a longer life mean a healthier life? The number of adults over 65 in the United States is growing, but many may not be aware that they are at greater risk from foodborne diseases and their nutritional needs change as they age. The IOM's Food Forum held a workshop October 29-30, 2009, to discuss food safety and nutrition concerns for older adults.
Author: Yousef Al-Dashti
Author: Yousef Al-Dashti
Author: Cinthia Bau Betim Cazarin
Author: Ronald Ross Watson
Author: Bijaya Prasad Upadhyaya
Author: Donato F. Romagnolo
Author: Blanca Hernandez-Ledesma
Author: María Chávarri Hueda
Author: Dragana Djurica
Author: Sang-Woon Choi
Author: Institute of Medicine