Author: Emanuel WaletzkyPublisher:
ISBN:
Category :
Languages : en
Pages : 154
Book Description
The Genetics and Manifestations of Certain New Mutations in Drosophila Melanogaster
Author: Emanuel WaletzkyMutation and Evolution
Author: Ronny C. WoodruffPublisher: Springer Science & Business Media
ISBN: 9401152101
Category : Science
Languages : en
Pages : 561
Book Description
Although debated since the time of Darwin, the evolutionary role of mutation is still controversial. In over 40 chapters from leading authorities in mutation and evolutionary biology, this book takes a new look at both the theoretical and experimental measurement and significance of new mutation. Deleterious, nearly neutral, beneficial, and polygenic mutations are considered in their effects on fitness, life history traits, and the composition of the gene pool. Mutation is a phenomenon that draws attention from many different disciplines. Thus, the extensive reviews of the literature will be valuable both to established researchers and to those just beginning to study this field. Through up-to-date reviews, the authors provide an insightful overview of each topic and then share their newest ideas and explore controversial aspects of mutation and the evolutionary process. From topics like gonadal mosaicism and mutation clusters to adaptive mutagenesis, mutation in cell organelles, and the level and distribution of DNA molecular changes, the foundation is set for continuing the debate about the role of mutation, fitness, and adaptability. It is a debate that will have profound consequences for our understanding of evolution.
Conditional Mutations and New Genes in Drosophila
Author: Boris ChadovPublisher:
ISBN:
Category : Science
Languages : en
Pages : 0
Book Description
A new class of mutations of Drosophila melanogaster has been generated with the help of Œ≥-irradiation and a new selection procedure; the mutations were named conditional. According to the data of genetic analysis, these mutations are discrete regions in DNA but are different from the Mendelian protein-coding genes. The genes associated with these mutations are named ontogenes. The general pattern of mutation manifestation matches the pattern characteristic of genetic incompatibility in distant hybridization. Development of monstrosities and the observed meiotic abnormalities suggest that ontogenes control the processes providing the proper spatial cell arrangement and switch-on of protein-coding genes. Ontogenes are active at all stages of the soma,Äôs life cycle and germinal tissue. In the character of their manifestation, the ontogenes correspond to the long noncoding RNAs in molecular genetics. The developed methods for generating mutant drosophila strains allow the manifestation and population dynamics of the mutants for this important group of genes to be studied.
The third-chromosome group of mutant characters of Drosophila melanogaster
Author: Calvin Blackman BridgesPublisher:
ISBN: 9781258763213
Category : Drosophila melanogaster
Languages : en
Pages : 268
Book Description
Genetic Variations of Drosophila Melanogaster
Author: Dan L. LindsleyPublisher: Carnegie Institute (WA)
ISBN:
Category : Nature
Languages : en
Pages : 506
Book Description
Health Effects of Exposure to Low Levels of Ionizing Radiation
Author: National Research CouncilPublisher: National Academies
ISBN: 0309039959
Category : Science
Languages : en
Pages : 436
Book Description
This book reevaluates the health risks of ionizing radiation in light of data that have become available since the 1980 report on this subject was published. The data include new, much more reliable dose estimates for the A-bomb survivors, the results of an additional 14 years of follow-up of the survivors for cancer mortality, recent results of follow-up studies of persons irradiated for medical purposes, and results of relevant experiments with laboratory animals and cultured cells. It analyzes the data in terms of risk estimates for specific organs in relation to dose and time after exposure, and compares radiation effects between Japanese and Western populations.
Genetic and Bioinformatic Screening for Behavioural Mutations in Drosophila Melanogaster
Author: Edward Wilhelm GreenPublisher:
ISBN:
Category :
Languages : en
Pages : 277
Book Description
In the post-genomic era, the question of how genes give rise to the observable diversity of morphology, physiology, behaviour and disease susceptibility is becoming of one central importance. Even in a model system as well studied as the fruit fly Drosophila melanogaster, the function of the vast majority of genes, and the mechanisms by which they give rise to such diversity, remains unknown. Drosophila behaviour represents a sensitive system in which to evaluate novel methods of determining gene function. Traditionally the analysis of behavioural phenotypes has represented a time consuming, highly subjective process. I have developed a suite of automated analysis tools (the BeFly! package) that has not only made such analyses both quicker and more objective, but has also allowed data to be examined in greater depth by making complex algorithms more accessible to users. The BeFly! package was initially used to characterise a serendipitously identified circadian mutant strain provisionally named Party on. As the Party on gene could not be conclusively mapped, and a meta analysis of existing circadian microarray data suggested that many circadian genes remained to be identified, BeFly!'s high throughput tools were employed in a novel systems biology screen in which phenotypic analysis was combined with gene expression data to identify likely gene function. This approach generated a number of novel candidate clock genes, the roles of which were further analysed using RNAi knockdown, confirming that the neuropeptide gene Adipokinetic hormone-like played a role in the clock mechanism. Given the success of our new strategy, it was widened to identify genes controlling sleep in Drosophila, leading to the identification of several genes associated with distinct aspects of sleep. In conclusion, the tools and methods developed in this thesis represent a novel, sensitive method for determining gene function applicable beyond the Drosophila model.
Sex-linked Inheritance in Drosophila
Author: Thomas Hunt MorganPublisher:
ISBN:
Category : Drosophila
Languages : en
Pages : 98
Book Description
The Third-chromosome Group of Mutant Characters of Drosophila Melanogaster
Author: Calvin Blackman BridgesPublisher: Legare Street Press
ISBN: 9781016839716
Category : History
Languages : en
Pages : 0
Book Description
This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
Studies in Genetics
Author: Hermann Joseph MullerPublisher:
ISBN:
Category : Science
Languages : en
Pages : 640
Book Description