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The Fall and Rise of Aspirin

The Fall and Rise of Aspirin PDF Author: Peter Sheldon
Publisher:
ISBN:
Category : Health & Fitness
Languages : en
Pages : 316

Book Description
The author has long been interested in how plant derived substances can prove beneficial to Medicine. Writings on papyrus from the earliest times have described the use of willow bark for soothing inflamed wounds. Major contributions by the Reverend Edward Stone of Chipping Norton, and Dr. Thomas Maclagan of Dundee are covered, along with the unique discovery by Professor John Vane and his team, of the fundamental effect of aspirin on prostaglandin synthesis. The book includes fascinating memorabilia on the early days of aspirin, kindly donated from the Bayer archive.In his first book on the foxglove, the author described how Nature's gift of digitalis came to become accepted worldwide as a valuable treatment for heart failure. Now, he has explored the bark of the willow, from which by chemical modification, aspirin was obtained. But whereas up to now, digitalis (in its current form, digoxin), only has a place in the treatment of heart disease, aspirin ? the world's most ubiquitous pain killer, has in the last half-century, been shown also to prevent heart attacks and strokes. And in addition it may soon come into use in cancer prevention.The author is currently a practising consultant rheumatologist at Leicester Royal Infirmary who, in former years, prescribed prodigious amounts of aspirin for the treatment of rheumatoid arthritis. As an immunologist at the University of Leicester, he has taught medical students from the inception of its medical school.

The Fall and Rise of Aspirin

The Fall and Rise of Aspirin PDF Author: Peter Sheldon
Publisher:
ISBN:
Category : Health & Fitness
Languages : en
Pages : 316

Book Description
The author has long been interested in how plant derived substances can prove beneficial to Medicine. Writings on papyrus from the earliest times have described the use of willow bark for soothing inflamed wounds. Major contributions by the Reverend Edward Stone of Chipping Norton, and Dr. Thomas Maclagan of Dundee are covered, along with the unique discovery by Professor John Vane and his team, of the fundamental effect of aspirin on prostaglandin synthesis. The book includes fascinating memorabilia on the early days of aspirin, kindly donated from the Bayer archive.In his first book on the foxglove, the author described how Nature's gift of digitalis came to become accepted worldwide as a valuable treatment for heart failure. Now, he has explored the bark of the willow, from which by chemical modification, aspirin was obtained. But whereas up to now, digitalis (in its current form, digoxin), only has a place in the treatment of heart disease, aspirin ? the world's most ubiquitous pain killer, has in the last half-century, been shown also to prevent heart attacks and strokes. And in addition it may soon come into use in cancer prevention.The author is currently a practising consultant rheumatologist at Leicester Royal Infirmary who, in former years, prescribed prodigious amounts of aspirin for the treatment of rheumatoid arthritis. As an immunologist at the University of Leicester, he has taught medical students from the inception of its medical school.

Aspirin

Aspirin PDF Author: Diarmuid Jeffreys
Publisher: Chemical Heritage Foundation
ISBN: 1596918160
Category : Health & Fitness
Languages : en
Pages : 352

Book Description
A fast-paced, medical-historical mystery, filled with twists and turns.-Chicago Tribune

Children and Drug Safety

Children and Drug Safety PDF Author: Cynthia A Connolly
Publisher: Rutgers University Press
ISBN: 0813575230
Category : Health & Fitness
Languages : en
Pages : 328

Book Description
Winner of the 2018 Arthur J. Viseltear Award from the Medical Care Section of the American Public Health Association​ Children and Drug Safety traces the development, use, and marketing of drugs for children in the twentieth century, a history that sits at the interface of the state, business, health care providers, parents, and children. This book illuminates the historical dimension of a clinical and policy issue with great contemporary significance—many of the drugs administered to children today have never been tested for safety and efficacy in the pediatric population. Each chapter of Children and Drug Safety engages with major turning points in pediatric drug development; themes of children’s risk, rights, protection and the evolving context of childhood; child-rearing; and family life in ways freighted with nuances of race, class, and gender. Cynthia A. Connolly charts the numerous attempts by Congress, the Food and Drug Administration, the American Academy of Pediatrics, and leading pediatric pharmacologists, scientists, clinicians, and parents to address a situation that all found untenable. Open access edition funded by the National Endowment for the Humanities. The text of this book is licensed under a Creative Commons Attribution NonCommercial-NoDerivatives 4.0 International License: https://creativecommons.org/licenses/by-nc-nd/4.0/

An Aspirin a Day

An Aspirin a Day PDF Author: Dr Keith Souter
Publisher: Michael O'Mara Books
ISBN: 1843177188
Category : Medical
Languages : en
Pages : 207

Book Description
Comprehensive and informative, this fascinating book is essential reading for everyone, teaching how this cheap and readily available drug can protect you.

The Aspirin Wars

The Aspirin Wars PDF Author: Charles C. Mann
Publisher: Knopf Publishing Group
ISBN:
Category : Business & Economics
Languages : en
Pages : 456

Book Description
The history of competition in the aspirin industry.

Owning the Sun

Owning the Sun PDF Author: Alexander Zaitchik
Publisher: Catapult
ISBN: 164009590X
Category : Business & Economics
Languages : en
Pages : 305

Book Description
For readers of Bad Blood and Empire of Pain, an authoritative look at monopoly medicine from the dawn of patents through the race for COVID-19 vaccines and how the privatization of public science has prioritized profits over people Owning the Sun tells the story of one of the most contentious fights in human history: the legal right to produce lifesaving medicines. Medical science began as a discipline geared toward the betterment of all human life, but the merging of research with intellectual property and the rise of the pharmaceutical industry warped and eventually undermined its ethical foundations. Since World War II, federally funded research has facilitated most major medical breakthroughs, yet these drugs are often wholly controlled by price-gouging corporations with growing international ambitions. Why does the U.S. government fund the development of medical science in the name of the public only to relinquish exclusive rights to drug companies, and how does such a system impoverish us, weaken our responses to crises, and, as in the cases of AIDS and COVID-19, put the world at risk? Outlining how generations of public health and science advocates have attempted to hold the line against Big Pharma and their allies in government, Alexander Zaitchik’s first-of-its-kind history documents the rise of privatized medicine in the United States and its subsequent globalization. From the controversial arrival of patent-wielding German drug firms in the late nineteenth century to present-day coordination between industry and philanthropic organizations—including the influential Bill & Melinda Gates Foundation—that stymie international efforts to vaccinate the world against COVID-19, Owning the Sun tells one of the most important and least understood histories of our time.

Drug-Induced Liver Injury

Drug-Induced Liver Injury PDF Author:
Publisher: Academic Press
ISBN: 0128173173
Category : Medical
Languages : en
Pages : 290

Book Description
Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series

Acetylsalicylic Acid

Acetylsalicylic Acid PDF Author: Karsten Schrör
Publisher: John Wiley & Sons
ISBN: 3527338055
Category : Science
Languages : en
Pages : 474

Book Description
Written by a leading expert on Aspirin-related research, this is the most comprehensive treatise on the pharmacological effects and clinical applications of one of the most successful drugs ever. The text is written with a wide audience in mind, and to be readily understandable for clinicians, pharmacists, biomedical researchers and pharmacologists alike. This second, completely revised edition contains the latest results of clinical and pharmacological research on Acetylsalicylic acid, addressing the multiple pharmacological properties of this famous drug with a balanced view on their translation into clinical practice, including prevention from cardiovascular diseases and colorectal cancer.

Every Molecule Tells a Story

Every Molecule Tells a Story PDF Author: Simon Cotton
Publisher: CRC Press
ISBN: 1439807736
Category : Medical
Languages : en
Pages : 283

Book Description
From cooking to medicine, from engineering to art, chemistry—the science of molecules—is everywhere. A celebration of the molecules of chemistry, Every Molecule Tells a Story celebrates the molecules responsible for the experiences of everyday life: the air we breathe; the water we drink; the chemicals that fuel our living; the steroids that give us sex; the colours of the seasons; the drugs that heal us; and the scented molecules that enrich our diet and our encounters with each other. You can’t see them, but you know that they are there. Unveiling the structures of poisonous "natural" substances and beneficial man-made molecules, this book brushes away any preconceived notions about chemistry to demonstrate why and how molecules matter.

Molecules That Amaze Us

Molecules That Amaze Us PDF Author: Paul May
Publisher: CRC Press
ISBN: 1466589604
Category : Science
Languages : en
Pages : 746

Book Description
"This new book is by two knowledgeable and expert popularizers of chemistry and deals exclusively with molecules and compounds rather than with the simpler atoms and elements. It is based on the very successful ‘Molecule of the Month’ website that was begun by Paul May fifteen years ago and to which his co-author Simon Cotton has been a frequent contributor. ... The authors ... strike an excellent balance between introducing the novice to the world of molecules while also keeping the expert chemist interested. ... I highly recommend this book to all readers. It will vastly expand your knowledge and horizons of chemistry and the human ingenuity that surrounds it." —From the Foreword by Dr. Eric Scerri, UCLA, Los Angeles, website: www.ericscerri.com, Author of ‘The Periodic Table, Its Story and Its Significance’ and several other books on the elements and the periodic table. The world is composed of molecules. Some are synthetic while many others are products of nature. Molecules That Amaze Us presents the stories behind many of the most famous and infamous molecules that make up our modern world. Examples include the molecule responsible for the spicy heat in chilies (capsaicin), the world’s first synthetic painkiller (aspirin), the pigment responsible for the color of autumn leaves (carotene), the explosive in dynamite (nitroglycerine), the antimalarial drug (quinine), the drug known as "speed" (methamphetamine), and many others. Other molecules discussed include caffeine, adrenaline, cholesterol, cocaine, digitalis, dopamine, glucose, insulin, methane, nicotine, oxytocin, penicillin, carbon dioxide, limonene, and testosterone. In all, the book includes 67 sections, each describing a different molecule, what it does, how it is made, and why it is so interesting. Written by experts in the field, the book is accessible and easy to read. It includes amusing anecdotes, historical curiosities, and entertaining facts about each molecule, thereby balancing educational content with entertainment. The book is heavily illustrated with relevant photographs, images, and cartoons—the aim being both to educate and entertain.