Author: Kent Bradley BergPublisher:
ISBN:
Category : Pathogenic microorganisms
Languages : en
Pages : 182
Book Description
The Evolution of Virulence in Vibrio Cholerae
Author: Kent Bradley BergPublisher:
ISBN:
Category : Pathogenic microorganisms
Languages : en
Pages : 182
Book Description
Evolution of Virulence in Vibrio Cholerae
Author: Nicole Mariner HarrisonPublisher:
ISBN:
Category : Cholera
Languages : en
Pages : 90
Book Description
The Evolution of Virulence in Vibrio Cholerae
Author: Wahid Pierre ChammasPublisher:
ISBN:
Category : Vibrio cholerae
Languages : en
Pages : 246
Book Description
Evolution of Virulence of Vibrio Cholerae
Author: Jeremy Broder SussmanPublisher:
ISBN:
Category : Vibrio cholerae
Languages : en
Pages : 142
Book Description
Vibrios in the Environment
Author: Rita R. ColwellPublisher: Wiley-Interscience
ISBN:
Category : Medical
Languages : en
Pages : 656
Book Description
Horizontal Gene Transfer, Virulence and the Evolution of Pathogenic Vibrio Cholerae
Author: Yvonne Ann O'SheaPublisher:
ISBN:
Category : Vibrio cholerae
Languages : en
Pages : 166
Book Description
Vibrio cholerae is a Gram negative, curved, rod shaped bacterium. V. cholerae is the etiological agent of the diarrheal disease cholera. Of the 200 O antigen serogroups, only 01 and 0139 are known to cause epidemic and pandemic cholera. The 01 serogroup strains are divided into two biotypes classical and E1 Tor. Investigators have long sought to understand the evolution of 7th pandemic El Tor and 0139 strains. Examination of the evolutionary relationships and multilocus virulence gene profiles of V. cholerae isolates indicated that consecutive pandemic strains arose from a common 01 serogroup progenitor through the successive acquisition of new virulence regions. One such region is the Vibrio pathogenicity island (VPI) encoding the toxin co-regulated pilus (TCP) an essential host colonisation factor. The mechanism of transfer of the VPI is unclear, however in this thesis it was shown that the VPI could be transferred between V. cholerae 01 serogroup strains, via a generalised transducing phage. Previously, it was shown that certain chromosomal regions are unique to V. cholerae biotype El Tor strains, which may have led to the success of the 7th pandemic strains. For example the 7.5 kb Vibrio seventh pandemic island II (VSP-II), is one such region. In this thesis, it was found that the 7.5 kb genomic island (GI) is part of a novel 26.9 kb GI and that it shows homology to a 43.4 kb GI in V. vulnificus strain YJ016. It has been suggested that V. cholerae biotype El Tor strains persist longer in aquatic ecosystems. In this thesis, I examined the role of the stringent starvation protein A (ssaA) in stress survival. I investigated growth of a V. cholerae sspAB nutant under a range of physiological stress conditions and show that mutaions in these genes did not effect survival. The evolutionary success of V. cholerae as an endemic and pandemic pathogen may be more related to its improved interaction with the human host that to its improved fitness within environmental reservoirs.
Molecular Medical Microbiology
Author: Yi-Wei TangPublisher: Academic Press
ISBN: 0123977630
Category : Science
Languages : en
Pages : 2214
Book Description
The molecular age has brought about dramatic changes in medical microbiology, and great leaps in our understanding of the mechanisms of infectious disease. Molecular Medical Microbiology is the first book to synthesise the many new developments in both molecular and clinical research in a single comprehensive resource. This timely and authoritative three-volume work is an invaluable reference source of medical bacteriology. Comprising more than 100 chapters, organized into 17 major sections, the scope of this impressive work is wide-ranging. Written by experts in the field, chapters include cutting-edge information, and clinical overviews for each major bacterial group, in addition to the latest updates on vaccine development, molecular technology and diagnostic technology. Topics covered include bacterial structure, cell function, and genetics; mechanisms of pathogenesis and prevention; antibacterial agents; and infections ranging from gastrointestinal to urinary tract, centrtal nervous system, respiratory tract, and more. - The first comprehensive and accessible reference on molecular medical microbiology - Full color presentation througout - In-depth discussion of individual pathogenic bacteria in a system-oriented approach - Includes a clinical overview for each major bacterial group - Presents the latest information on vaccine development, molecular technology, and diagnostic technology - More than 100 chapters covering all major groups of bacteria - Written by an international panel of authors who are experts in their respective disciplines
Vibrio Cholerae and Cholera
Author: Kaye WachsmuthPublisher:
ISBN:
Category : Cholera
Languages : en
Pages : 488
Book Description
Presents the latest molecular studies of virulence, colonization, gene regulation, and the O1 antigen. Gives an in-depth and analytical approach to the epidemiology of cholera that includes outbreak investigations, case-control studies, and surveillance functions. Describes the molecular approach to epidemiologic problems and questions. Tracks the global spread of cholera by genetically defining individual strains. Addresses possible intervention and prevention strategies, including the latest vaccines, and their public health relevance.
Virulence of Brazilian Vibrio Cholerae Evolution and Growth Effects
Author: Matthew Thomas DistlerPublisher:
ISBN:
Category : Vibrio cholerae
Languages : en
Pages : 102
Book Description
An Evolutionary Perspective on the Regulation of Virulence in Vibrio Cholerae
Author: Nathan Walter GoehringPublisher:
ISBN:
Category : Vibrio cholerae
Languages : en
Pages : 176
Book Description