An Evaluation of Beta-blockers, Calcium Antagonists, Nitrates, and Alternative Therapies for Stable Angina PDF Download

Author: Paul A. Heidenreich
Publisher: Agency for Healthcare Research & Quality
ISBN:
Category : Medical
Languages : en
Pages : 140

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Author: Joel Morganroth
Publisher:
ISBN: 9789024723362
Category :
Languages : en
Pages : 410

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Author: Joel Morganroth
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Author: J. Morganroth
Publisher: Springer Science & Business Media
ISBN: 9400975619
Category : Medical
Languages : en
Pages : 409

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Book Description
With the beginning of the 1980's it was becoming increasingly evident that the lack of approval of new cardiovascular agents for use by clinicians in the United States for the treatment of cardiovascular disorders was becoming a problem. Patients requiring medical therapy for hypertension, angina pectoris, arrhythmias, congestive heart failure, and vasospastic disorders of the coronary arteries could receive in the United States only a small number of the drugs available to physicians in the rest of the world. In fact, as the 1980's began, there was only one available beta blocking agent released by The Food and Drug Administration; and even as of this writing, no oral calcium antagonist agent. This lag, in part, has been due to the confusion of proper and expeditious methods to define safety and efficacy of such agents so that the United States regulatory agency (Food and Drug Administration) could approve the use of such agents by clinicians. The vast number of new beta blocker and calcium antagonist agents being developed, as well as the long-term use abroad of many new drugs, has raised important questions as to how relative safety and efficacy of such agents can be determined to facilitate availability in the United States.

Author: Diana B. Petitti
Publisher: OUP USA
ISBN: 0195133641
Category : Language Arts & Disciplines
Languages : en
Pages : 319

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Book Description
Public health and in health policy courses at the undergraduate and graduate level.

Author: Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure
Publisher:
ISBN:
Category : Hypertension
Languages : en
Pages : 20

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Author: Karim Ratib
Publisher: CRC Press
ISBN: 0340974222
Category : Medical
Languages : en
Pages : 290

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Book Description
This fully revised and updated second edition of Emergency Cardiology offers highly practical advice on the diagnosis and management of acute cardiac conditions. Throughout the book the authors employ an evidence-based approach to clinical practice, and provide detailed guidance for day-to-day practice in a wider variety of settings - from the emergency department to intensive care and the cardiac ward. Provides essential advice for the rapid diagnosis and management of cardiac emergencies - both common and more rare. Includes evidence-based guidelines and the results of the most groundbreaking clinical trials Practical format pocket-sized format Authored by four cardiologists with extensive experience in the emergency setting Emergency Cardiology, Second Edition is an essential purchase for junior doctors, emergency department staff, trainees in cardiology and specialist nurses.

Author: Charles Antzelevitch
Publisher: Springer
ISBN: 3319315781
Category : Medical
Languages : en
Pages : 342

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Book Description
This book delineates the state of the art of the diagnosis and treatment of J wave syndromes, as well as where future research needs to be directed. It covers basic science, translational and clinical aspects of these syndromes. The authors are leading experts in their respective fields, who have contributed prominently to the literature concerning these topics. J wave syndromes are one of the hottest topics in cardiology today. Cardiac arrhythmias associated with Brugada syndrome (BrS) or an early repolarization (ER) pattern in the inferior or infero-lateral ECG leads are thought to be mechanistically linked to accentuation of transient outward current (Ito)-mediated J waves. Although BrS and ER syndrome (ERS) differ with respect to magnitude and lead location of abnormal J waves, they are thought to represent a continuous spectrum of phenotypic expression termed J wave syndromes. ERS is divided into three subtypes with the most severe, Type 3, displaying an ER pattern globally in the inferior, lateral and right precordial leads. BrS has been linked to mutations in 19 different genes, whereas ERS has been associated with mutations in 7 different genes. There is a great deal of confusion as to how to properly diagnose and treat the J wave syndromes as well as confusion about the underlying mechanisms. The demonstration of successful epicardial ablation of BrS has provided new therapeutic options for the management of this syndrome for which treatment alternatives are currently very limited, particularly in the case of electrical storms caused by otherwise uncontrollable recurrent VT/VF. An early repolarization pattern is observed in 2-5% of the US population. While it is clear that the vast majority of individuals exhibiting an ER pattern are not at risk for sudden cardiac death, the challenge moving forward is to identify those individuals who truly are at risk and to design safe and effective treatments.

Author: Charles Antzelevitch
Publisher: John Wiley & Sons
ISBN: 1405146818
Category : Medical
Languages : en
Pages : 248

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Book Description
Until recently, the cellular basis for sudden death, the BrugadaSyndrome, has largely remained an unknown to modernarrhythmologists and cardiologists, particularly in the absence ofany structural heart disease. Detailed observations of age-groups,especially the young, families and populations where sudden deathfrequently occurs, and improved understanding of its contributoryfactors and mechanisms are, however, showing the way forward. This addition to the Clinical Approaches to Tachyarrhythmias(CATA) Series, written by the investigators who discovered andprobed the Brugada Syndrome, discusses the history, etiology,pathology and clinical manifestations of sudden death. Fromdiagnosis, prognosis, to therapeutic approaches using the latest incathater ablation techniques, electrophysiological surgery, andgenetic appraisal, the work is a testimony to the author'sinvestigation. Using clinical cases in Thailand and Laos, theyfurther unravel the syndrome's molecular mechanisms, studyingrelated syndromes, such as the long-QT syndrome, infant death, andarryhthmogenic right ventricular cardiomyopathy. By being informed of the electrophysiological abnormalities thatcontribute to familial and genetic diseases, physicians,cardiologists and all those who care for patients with cardiacarrhythmias will be better able to identify and treat patients inwhom the Brugada Syndrome may strike next.

Author: Derek Hausenloy
Publisher: Oxford University Press
ISBN: 019954476X
Category : Medical
Languages : en
Pages : 138

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Book Description
Coronary heart disease (CHD) is the leading cause of death worldwide. Cardioprotection refers to the prevention of CHD and the clinical improvement in patients suffering from cardiovascular problems.