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The Common Marmoset in Captivity and Biomedical Research

The Common Marmoset in Captivity and Biomedical Research PDF Author: Robert P. Marini
Publisher: Academic Press
ISBN: 012811830X
Category : Science
Languages : en
Pages : 572

Book Description
The Common Marmoset in Captivity and Biomedical Research is the first text dedicated exclusively to this species,filling an urgent need for an encyclopedic compilation of the existing information. Sponsored by the AmericanCollege of Laboratory Animal Medicine as part of its authoritative Blue Book series, the book covers the biology,management, diseases, and clinical and research applications of this important species. The common marmoset(Callithrix jacchus) has come of age in the scientific community as a behaviorally complex, cognitively advanced,small, prolific, and easily maintained nonhuman primate with many of the advantages of larger animals, such asmacaques, but without the attendant physical and zoonotic risks. Marmosets are currently being used in diverse areas of inquiry, including vision and auditory research, infectious disease, cognitive neuroscience, behavior, reproductive biology, toxicology and drug development, and aging. Themarmoset genome has been sequenced and there is currently an intensive effort to apply gene editing technologies to the species. The creation of transgenic marmosets will provide researchers with a small nonhuman primatemodel to study a number of poorly understood disorders, like autism. - Presents a complete view of the marmoset, covering their biology and management, diseases and clinical applications, and research applications - Includes contributions from renowned and international authors and editors - Provides the first authoritative and comprehensive treatment of marmosets in biomedical research as part of the ACLAM Series

The Common Marmoset in Captivity and Biomedical Research

The Common Marmoset in Captivity and Biomedical Research PDF Author: Robert P. Marini
Publisher: Academic Press
ISBN: 012811830X
Category : Science
Languages : en
Pages : 572

Book Description
The Common Marmoset in Captivity and Biomedical Research is the first text dedicated exclusively to this species,filling an urgent need for an encyclopedic compilation of the existing information. Sponsored by the AmericanCollege of Laboratory Animal Medicine as part of its authoritative Blue Book series, the book covers the biology,management, diseases, and clinical and research applications of this important species. The common marmoset(Callithrix jacchus) has come of age in the scientific community as a behaviorally complex, cognitively advanced,small, prolific, and easily maintained nonhuman primate with many of the advantages of larger animals, such asmacaques, but without the attendant physical and zoonotic risks. Marmosets are currently being used in diverse areas of inquiry, including vision and auditory research, infectious disease, cognitive neuroscience, behavior, reproductive biology, toxicology and drug development, and aging. Themarmoset genome has been sequenced and there is currently an intensive effort to apply gene editing technologies to the species. The creation of transgenic marmosets will provide researchers with a small nonhuman primatemodel to study a number of poorly understood disorders, like autism. - Presents a complete view of the marmoset, covering their biology and management, diseases and clinical applications, and research applications - Includes contributions from renowned and international authors and editors - Provides the first authoritative and comprehensive treatment of marmosets in biomedical research as part of the ACLAM Series

Reproduction in New World Primates

Reproduction in New World Primates PDF Author: J.P. Hearn
Publisher: Springer Science & Business Media
ISBN: 9400973225
Category : Medical
Languages : en
Pages : 219

Book Description
The New World primates are becoming widely used in scientific and medical work in fields from anthropology to zoology, behaviour to urology. They have unique attributes for studies in cancer, infectious diseases, genetics, virology and reproduction. However, it is only now that their reproductive physiology is being clarified in any depth and this book is a first synthesis of that knowledge. The nine authors involved in this project have presented an up to date account of the major New World species used in biological and medical science. In addition to their distribution and conservation in the wild, essential biological data from laboratory studies are presented on reproductive cycles, gestation length, seasonal breeding, puberty and other factors. The major applications of these species in research are explored. Whenever possible, research workers should steer away from using endangered species in their studies. The New World monkeys used in research in any numbers are still fairly common ~n the wild, yet their greatest advantages are ~n their smalle size and high fecundity. This makes possible the establishment of self sustaining captive breeding colonies at a fraction of the time and cost necessary for the more conventional Old World laboratory primates. Consequently the drain on wild stocks need not be extensive as only breeding nuclei should be necessary.

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment PDF Author: Joerg Bluemel
Publisher: Academic Press
ISBN: 012417146X
Category : Medical
Languages : en
Pages : 716

Book Description
The Nonhuman Primate in Drug Development and Safety Assessment is a valuable reference dedicated to compiling the latest research on nonhuman primate models in nonclinical safety assessment, regulatory toxicity testing and translational science. By covering important topics such as study planning and conduct, inter-species genetic drift, pathophysiology, animal welfare legislation, safety assessment of biologics and small molecules, immunotoxicology and much more, this book provides scientific and technical insights to help you safely and successfully use nonhuman primates in pharmaceutical toxicity testing. A comprehensive yet practical guide, this book is intended for new researchers or practicing toxicologists, toxicologic pathologists and pharmaceutical scientists working with nonhuman primates, as well as graduate students preparing for careers in this area. - Covers important topics such as species selection, study design, experimental methodologies, animal welfare and the 3Rs (Replace, Refine and Reduce), social housing, regulatory guidelines, comparative physiology, reproductive biology, genetic polymorphisms and more - Includes practical examples on techniques and methods to guide your daily practice - Offers a companion website with high-quality color illustrations, reference values for safety assessment and additional practical information such as study design considerations, techniques and procedures and dosing and sampling volumes

The Embryology of the Common Marmoset

The Embryology of the Common Marmoset PDF Author: I. R. Phillips
Publisher:
ISBN: 9783642664977
Category :
Languages : en
Pages : 52

Book Description


Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research

Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309488516
Category : Science
Languages : en
Pages : 123

Book Description
The marmoset, a type of small monkey native to South America, is a research model of increasing importance for biomedical research in the United States and globally. Marmosets offer a range of advantages as animal models in neuroscience, aging, infectious diseases, and other fields of study. They may be particularly useful for the development of new disease models using genetic engineering and assisted reproductive technologies. However, concerns have been voiced with respect to the development of new marmoset-based models of disease, ethical considerations for their use, the supply of marmosets available for research, and gaps in guidance for their care and management. To explore and address these concerns, the Roundtable on Science and Welfare in Laboratory Animal Use hosted a public workshop on October 22-23, 2018, in Washington, DC. The workshop focused on the availability of marmosets in the United States and abroad; animal welfare and ethical considerations stemming from the use of wildtype and genetically modified marmosets; and standards of housing and care, dietary needs, and feeding requirements for marmosets in captivity. This publication summarizes the presentations and discussions from the workshop.

Handbook of Exotic Pet Medicine

Handbook of Exotic Pet Medicine PDF Author: Marie Kubiak
Publisher: John Wiley & Sons
ISBN: 111938995X
Category : Medical
Languages : en
Pages : 524

Book Description
Easy-to-use, comprehensive reference covering the less common species encountered in general veterinary practice Handbook of Exotic Pet Medicine provides easy-to-access, detailed information on a wide variety of exotic species that can be encountered in general veterinary practice. Offering excellent coverage of topics such as basic techniques, preventative health measures, and a formulary for each species, each chapter uses the same easy-to-follow format so that users can find information quickly while working in the clinic. Presented in full colour, with over 400 photographs, the book gives small animal practitioners the confidence to handle and treat more familiar pets such as budgerigars, African grey parrots, bearded dragons, corn snakes, tortoises, pygmy hedgehogs, hamsters and rats. Other species that may be presented less frequently including skunks, marmosets, sugar gliders, koi carp, chameleons and terrapins are also covered in detail to enable clinicians to quickly access relevant information. Provides comprehensive coverage of many exotic pet species that veterinarians may encounter in general practice situations Presents evidence-based discussions of topics including biological parameters, husbandry, clinical evaluation, hospitalization requirements, common medical and surgical conditions, radiographic imaging, and more The Handbook of Exotic Pet Medicine is an ideal one-stop reference for the busy general practitioner seeing the occasional exotic animal, veterinary surgeons with an established exotic animal caseload, veterinary students and veterinary nurses wishing to further their knowledge.

The Embryology of the Common Marmoset

The Embryology of the Common Marmoset PDF Author: I.R. Phillips
Publisher: Springer Science & Business Media
ISBN: 3642664962
Category : Science
Languages : en
Pages : 47

Book Description
The primates represent a diverse group with the phylogenetic relationships of the var ious species reflected in their early embryonic development. The members of the Tupaiidae, Lemuridae and Lorisidae show great similarities to the lower mammals and even birds. The Tarsiidae represent an intermediate step and the Platyrrhini and Catarrhini exhibit the greatest similarities to man. During the period of embryogenesis, the dimensions of an embryo are insufficient guide to its age and much more reliable information can be derived from a study of its external form and internal structure. Examination of embryological specimens from a variety of simian species dates back to the early 1900's but much of this material was collected in a haphazard way from animals shot in the wild. Heuser and Streeter (1941) depicted a series of embryos of the rhesus monkey (Macaca mulatta) and correlated their gestational age with external form and size. Streeter (1951) arranged human em bryos, between 24. ± 1 and 47. ± 1 days of post-ovulation age, into age groups or devel opmental horizons based on their external form and internal structure. Each horizon was two days apart and numbered XI to XXIII. The transition from embryo to fetus occurred at the end of horizon XXIII and was arbitrarily dermed as the point where bone marrow invaded the cartilaginous precursor in the humerus. The earlier stages I-X have been dermed subsequently, (Heuser and Corner, 1957; O'Rahilly, 1973).

Marmosets and Tamarins

Marmosets and Tamarins PDF Author: Anthony B. Rylands
Publisher: Oxford Science Publications
ISBN: 9780198540229
Category : Science
Languages : en
Pages : 0

Book Description
Starting with concise accounts for all the marmoset and tamarin monkeys species, this important new book then goes on to review their geographical distributions and taxonomy, along with comparative reviews of vocalizations, scent-marking, mating systems, infant care and development, social organization, and behavior and ecology in the wild. Several of these small-primate species are rare or threatened, and the subjects discussed here are strongly relevant to their management in captivity as well as for understanding natural populations. This is the first volume in several years to review current knowledge of this family, which comprises 52 species and subspecies found in the area from Panama to southern Brazil.

Model Animals in Neuroendocrinology

Model Animals in Neuroendocrinology PDF Author: Mike Ludwig
Publisher: John Wiley & Sons
ISBN: 1119390885
Category : Medical
Languages : en
Pages : 462

Book Description
Model Animals in Neuroendocrinology: From Worm to Mouse to Man offers a masterclass on the opportunities that different model animals offer to the basic understanding of neuroendocrine functions and mechanisms of action and the implications of this understanding. The authors review recent advances in the field emanating from studies involving a variety of animal models, molecular genetics, imaging technologies, and behavior assays. These studies helped unravel mechanisms underlying the development and function of neuroendocrine systems. The book highlights how studies in a variety of model animals, including, invertebrates, fish, birds, rodents and mammals has contributed to our understanding of neuroendocrinology. Model Animals in Neuroendocrinology provides students, scientists and practitioners with a contemporary account of what can be learnt about the functions of neuroendocrine systems from studies across animal taxonomy. This is the seventh volume in the Masterclass in Neuroendocrinology Series, a co-publication between Wiley and the INF (International Neuroendocrine Federation) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.

The Marmoset Brain in Stereotaxic Coordinates

The Marmoset Brain in Stereotaxic Coordinates PDF Author: George Paxinos
Publisher: Academic Press
ISBN: 9780124158184
Category : Science
Languages : en
Pages : 0

Book Description
The Marmoset Brain in Stereotaxic Coordinates is the most comprehensive atlas of the brain of this animal available. The atlas is constructed in the style of The Rat Brain in Stereotaxic Coordinates, the most-cited book in neuroscience. It represents a collaboration between world leaders in neuroanatomy of the primate cortex and subcortex. It will be an indispensible tool for neuroanatomists, behavioral neuroscientists, and molecular biologists trying to understand the primate brain. ENDORSED BY SOCIETY FOR BRAIN MAPPING AND THERAPEUTICS (SBMT) - SBMT is a non-profit society organized for the purpose of encouraging basic and clinical scientists who are interested in areas of Brain Mapping, engineering, stem cell, nanotechnology, imaging and medical device to improve the diagnosis, treatment and rehabilitation of patients afflicted with neurological disorders. This society promotes the public welfare and improves patient care through the translation of new technologies/therapies into life saving diagnostic and therapeutic procedures. The Society is focused in breaking boundaries of science, technology, medicine, art and healthcare policy. For more information about how to become a member or participate in SBMT programs please visit: www.WorldBrainMapping.org