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The Efficacy of Dexedrine for the Sustainment of Helicopter Pilot Performance During 64 Hours of Continuous Wakefulness

The Efficacy of Dexedrine for the Sustainment of Helicopter Pilot Performance During 64 Hours of Continuous Wakefulness PDF Author: John A. Caldwell
Publisher:
ISBN: 9781423556657
Category : Amphetamines
Languages : en
Pages : 68

Book Description
The purpose of this investigation was to establish the efficacy of Dexedrine for sustaining aviator performance despite 64-hours of extended wakefulness. Although earlier flight studies yielded favorable results with no significant side effects, they were restricted to sleep-deprivation periods of only 40 hours. Due to requirements for longer periods of sustained wakefulness, it was necessary to study the efficacy of Dexedrine for maintaining aviator performance during 3 days and 2 nights without sleep. To accomplish this, computerized evaluations of aviator flight skills were conducted at regular intervals as subjects completed standardized flights in a UH-60 helicopter simulator, both: under Dexedrine and placebo. Laboratory-based assessments of cognitive, psychological, and central nervous system status were completed as well. Dexedrine (10 mg.) was given prophylactically (prior to signs of fatigue) at midnight, 0400, and 0800 on both deprivation days in one cycle, and placebo was given on both days in the other. Results indicated simulator flight performance was maintained by Dexedrine for up to 58 hours, while performance under placebo rapidly deteriorated. The drug was most beneficial

The Efficacy of Dexedrine for the Sustainment of Helicopter Pilot Performance During 64 Hours of Continuous Wakefulness

The Efficacy of Dexedrine for the Sustainment of Helicopter Pilot Performance During 64 Hours of Continuous Wakefulness PDF Author: John A. Caldwell
Publisher:
ISBN: 9781423556657
Category : Amphetamines
Languages : en
Pages : 68

Book Description
The purpose of this investigation was to establish the efficacy of Dexedrine for sustaining aviator performance despite 64-hours of extended wakefulness. Although earlier flight studies yielded favorable results with no significant side effects, they were restricted to sleep-deprivation periods of only 40 hours. Due to requirements for longer periods of sustained wakefulness, it was necessary to study the efficacy of Dexedrine for maintaining aviator performance during 3 days and 2 nights without sleep. To accomplish this, computerized evaluations of aviator flight skills were conducted at regular intervals as subjects completed standardized flights in a UH-60 helicopter simulator, both: under Dexedrine and placebo. Laboratory-based assessments of cognitive, psychological, and central nervous system status were completed as well. Dexedrine (10 mg.) was given prophylactically (prior to signs of fatigue) at midnight, 0400, and 0800 on both deprivation days in one cycle, and placebo was given on both days in the other. Results indicated simulator flight performance was maintained by Dexedrine for up to 58 hours, while performance under placebo rapidly deteriorated. The drug was most beneficial

The Efficacy of Dexedrine for the Sustainment of Helicopter Pilot Performance During 64 Hours of Continuous Wakefulness

The Efficacy of Dexedrine for the Sustainment of Helicopter Pilot Performance During 64 Hours of Continuous Wakefulness PDF Author: John A. Caldwell
Publisher:
ISBN:
Category : Amphetamines
Languages : en
Pages : 68

Book Description
The purpose of this investigation was to establish the efficacy of Dexedrine for sustaining aviator performance despite 64-hours of extended wakefulness. Although earlier flight studies yielded favorable results with no significant side effects, they were restricted to sleep-deprivation periods of only 40 hours. Due to requirements for longer periods of sustained wakefulness, it was necessary to study the efficacy of Dexedrine for maintaining aviator performance during 3 days and 2 nights without sleep. To accomplish this, computerized evaluations of aviator flight skills were conducted at regular intervals as subjects completed standardized flights in a UH-60 helicopter simulator, both: under Dexedrine and placebo. Laboratory-based assessments of cognitive, psychological, and central nervous system status were completed as well. Dexedrine (10 mg.) was given prophylactically (prior to signs of fatigue) at midnight, 0400, and 0800 on both deprivation days in one cycle, and placebo was given on both days in the other. Results indicated simulator flight performance was maintained by Dexedrine for up to 58 hours, while performance under placebo rapidly deteriorated. The drug was most beneficial.

Effects of Psychoactive Chemicals on Commercial Driver Health and Performance: Stimulants, Hypnotics, Nutritional, and Other Supplements

Effects of Psychoactive Chemicals on Commercial Driver Health and Performance: Stimulants, Hypnotics, Nutritional, and Other Supplements PDF Author: Gerald P Krueger
Publisher: Transportation Research Board
ISBN: 0309143225
Category : Transportation
Languages : en
Pages : 134

Book Description
TRB’s Commercial Truck and Bus Safety Synthesis Program (CTBSSP) Synthesis 19: Effects of Psychoactive Chemicals on Commercial Driver Health and Performance: Stimulants, Hypnotics, Nutritional, and Other Supplements identifies available information and research gaps relating to the use of chemical substances by commercial drivers and is intended to provide up-to-date information to inform decision makers about the near-, mid-, and long-range planning needs for research and educational outreach programs.

Taking Precautions Against Fatigue in Aviation

Taking Precautions Against Fatigue in Aviation PDF Author: YÜCEL BEYAZIT
Publisher: YÜCEL BEYAZIT
ISBN:
Category : Transportation
Languages : en
Pages : 59

Book Description
Taking Precautions Against Fatigue in Aviation Pilot fatigue is a significant problem in modern aviation operations, largely because of the unpredictable work hours, long duty periods, circadian disruptions, and insufficient sleep that are commonplace in both civilian and military flight operations. The full impact of fatigue is often underappreciated, but many of its deleterious effects have long been known. Compared to people who are well-rested, people who are sleep deprived think and move more slowly, make more mistakes and have memory difficulties. These negative effects may and do lead to aviation errors and accidents. In the 1930s, flight time limitations suggested lay-over durations, and aircrew sleep recommendations were developed in an attempt to mitigate aircrew fatigue. Unfortunately, there have been few changes to aircrew scheduling provisions and flight time limitations since the time they were first introduced, despite evidence that updates are needed. Although the scientific understanding of fatigue, sleep, shift work, and circadian physiology has advanced significantly over the past several decades, current regulations and industry practices have in large part failed to adequately incorporate the new knowledge.

Sleep & Safety

Sleep & Safety PDF Author: Salim Surani
Publisher: Bentham Science Publishers
ISBN: 1608052710
Category : Health & Fitness
Languages : en
Pages : 178

Book Description
"The National Highway Traffic Safety Administration (NHTSA) estimates that upto 4 percent of all fatal crashes are caused by drowsy driving and as many as 100,000 patients deaths per year may be due to fatigue related medical errors by doctors and nurses i"

Aerospace Health and Safety: Today and the Future

Aerospace Health and Safety: Today and the Future PDF Author: Irina Mordukhovich
Publisher: Frontiers Media SA
ISBN: 2832529364
Category : Science
Languages : en
Pages : 301

Book Description
Aviation plays vital roles in commerce, defense, science and leisure travel. Irrespective of the purpose of flight, crew and passengers are challenged by exposure to a variety of environmental conditions that can differ widely from work and travel environments on the surface of the Earth. With anticipated changes in aviation and space technology, new challenges to health and safety of crew and passengers can be expected. In this Research Topic, we welcome contributions from those whose work and interests are relevant to the health and safety of crew and passengers. This includes, but is not limited to, health and safety professionals, FAA examiners, corporate medical officers, aerospace and occupational physicians, physiologists, military and scientific team members, public health professionals, as well as engineers who are tasked with crew and passenger health and safety design projects. While 4.1 billion passengers fly on commercial airlines annually (and this figure is even higher when taking into account privately owned aircraft and military flight), for the most part aviation is safe. Passengers do arrive at their destinations with little concern to their own well-being and flight is generally well tolerated. However, older flyers, people with (diagnosed or undiagnosed) preexisting disease, and other vulnerable passengers (such as young children and pregnant women) may be at risk of complications and crew may be at special risk due to the frequency and duration of their many flight-related exposures. Health and safety issues for crew and passengers include but are not limited to: potentially severe circadian rhythm disruption, potential health effects of low-level cosmic ionizing radiation exposure at altitude, reduced oxygen delivery and tissue hypoxia at cabin pressurization, cabin air contamination by engine gases, toxic materials used in uniforms and some cabin seat materials, occupational noise, pesticides used for cabin disinsection, lack of adequate crew rest on layovers or between flights, cardiovascular demands of flight and effects of flight-related dehydration, the current absence of screening protocols especially in the context of a rising number of elderly and vulnerable flyers, lack of healthy nutrition at airports and in flight, availability of food and hydration as well as adequate cabin temperature under delay conditions, effects of alcohol use on flight-related physiological and behavioral health risks, anxiety and psychological distress associated with air travel, the effects of long-haul or ultra-long-haul flights on thromboembolic events as well as smoking cessation efforts and related psychological outcomes, job-related stress and harassment among crew. Cosmic ionizing and non-ionizing radiation exposure have drawn attention as have historic exposures of crew and passengers to second-hand cigarette smoke. The threat of political and interpersonal violence and altercations involving aviation cannot be overlooked. On-board medical emergencies run a wide gamut and the capacity to respond becomes more problematic as the duration of flights becomes longer or in the case of flight over oceans and the poles. In addition, in-flight and post flight embolisms and myocardial infarctions are more prevalent than might be expected. We hence encourage manuscripts that address in-flight medical response, including the capabilities on different types of aircraft on potential interventions by crew and medical volunteers. In addition, aviation as a vector for the carriage of disease is a significant concern to public health and security of populations world-wide, and we welcome submissions regarding infectious disease epidemiology and medicine as it relates to air travel. Insects and occasional unplanned travel by birds and rodents can present additional public health concerns. We are approaching an era where space travel may soon be increasingly common. Future flights for near-Earth orbit by leisure travelers and as well as travel to the moon and Mars raise a host of new questions with health and safety implications. What are the proposed health and safety accommodations going to be? Who will be allowed to travel? Perhaps the most interesting question is - who will make the rules?

Fatigue in Aviation: A Guide to Staying Awake at the Stick

Fatigue in Aviation: A Guide to Staying Awake at the Stick PDF Author: John A. Caldwell
Publisher: Routledge
ISBN: 1351936948
Category : Transportation
Languages : en
Pages : 167

Book Description
This overview of fatigue includes fatigue definitions, the measurement / assessment of fatigue, and the performance, mood, and safety problems associated with fatigue in the operational setting. The physiological bases of fatigue are discussed, so the reader understands that fatigue is a physiological phenomenon that is not "just a state of mind". Scientifically-valid countermeasures are discussed and data from a variety of sources are included to provide readers with a "toolbox" from which they can choose solutions to fatigue-related problems. The book is of interest to aviation crews in both civilian and military sectors, managers as well as aviators, flight deck as well as maintenance crews. It aims to be 'user-friendly', although scientific information is included to help the reader understand why certain behaviours occur.

Monitoring Metabolic Status

Monitoring Metabolic Status PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 030916611X
Category : Social Science
Languages : en
Pages : 468

Book Description
The U.S. military's concerns about the individual combat service member's ability to avoid performance degradation, in conjunction with the need to maintain both mental and physical capabilities in highly stressful situations, have led to and interest in developing methods by which commanders can monitor the status of the combat service members in the field. This report examines appropriate biological markers, monitoring technologies currently available and in need of development, and appropriate algorithms to interpret the data obtained in order to provide information for command decisions relative to the physiological "readiness" of each combat service member. More specifically, this report also provides responses to questions posed by the military relative to monitoring the metabolic regulation during prolonged, exhaustive efforts, where nutrition/hydration and repair mechanisms may be mismatched to intakes and rest, or where specific metabolic derangements are present.

Methamphetamine

Methamphetamine PDF Author: Ralph Weisheit
Publisher: Simon and Schuster
ISBN: 1592858384
Category : Reference
Languages : en
Pages : 328

Book Description
The definitive book on the impact of methamphetamine on individuals, communities, and society by two of America's leading addiction and criminal justice experts. In recent years, the media have inundated us with coverage of the horrors that befall methamphetamine users, and the fires, explosions, and toxic waste created by meth labs that threaten the well-being of innocent people. In Methamphetamine: Its History, Pharmacology, and Treatment, the first book in Hazelden's Library of Addictive Drugs series, Ralph Weisheit and William L. White examine the nature and extent of meth use in the United States, from meth's early reputation as a "wonder drug" to the current perception that it is a "scourge" of society.In separating fact from fiction, Weisheit and White provide context for understanding the meth problem by tracing its history and the varying patterns of use over time, then offer an in-depth look at:the latest scientific findings on the drug's effects on individualsthe myths and realities of the drug's impact on the mindthe national and international implications of methamphetamine productionthe drug's impact on rural communities, including a case study of two counties in the Midwestissues in addiction and treatment of meth.Thoroughly researched and highly readable, Methamphetamine offers a comprehensive understanding of medical, social, and political issues concerning this highly impactful drug.Written for professionals and serious lay readers by nationally recognized experts, the books in the Library of Addictive Drugs series feature in-depth, comprehensive, and up-to-date information on the most commonly abused mood-altering substances.

AGARD Index of Publications

AGARD Index of Publications PDF Author: North Atlantic Treaty Organization. Advisory Group for Aerospace Research and Development
Publisher:
ISBN:
Category : Aeronautics
Languages : en
Pages : 614

Book Description