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Author: G. Devereux Publisher: ISBN: Category : Languages : en Pages :
Book Description
There were two purposes to the work of this thesis (a) to identify the role of isometric training intensity in the training-induced reductions in resting blood pressure, and (b) to identify whether the mechanism for the reduced resting blood pressure is best reflected in what can be broadly termed cardiovascular, neuromuscular or metabolic markers of that training. Firstly, in a cross-sectional study, the only strong correlation was found between heart rate variability (a cardiovascular marker) and resting blood pressure. Secondly, this cardiovascular marker was also significantly affected by a single session of isometric exercise, an effect that persisted for at least 4 hours after exercise. However, thirdly, this marker and other cardiovascular markers (such as cardiac output and stroke volume) did not correlate with reductions in blood pressure seen after 4 weeks of isometric training. Instead, the training-induced reductions in blood pressure correlated strongly with neuromuscular and metabolic markers of isometric training. The extent to which local muscle fatigue was induced during isometric training correlated with the reductions in resting blood pressure. Therefore (a) isometric training intensity appears to be of utmost importance in the reductions in resting blood pressure (when bilateral-leg exercise is performed in 2 minute bouts), and (b) the mechanism whereby the adaptations in resting blood pressure occur is best reflected in neuromuscular and metabolic markers of local muscle fatigue during that training. These findings are discussed with a particular focus on the possible role of muscle metaboreceptor stimulation, during isometric training in the mechanism of training-induced reduction in resting blood pressure.
Author: G. Devereux Publisher: ISBN: Category : Languages : en Pages :
Book Description
There were two purposes to the work of this thesis (a) to identify the role of isometric training intensity in the training-induced reductions in resting blood pressure, and (b) to identify whether the mechanism for the reduced resting blood pressure is best reflected in what can be broadly termed cardiovascular, neuromuscular or metabolic markers of that training. Firstly, in a cross-sectional study, the only strong correlation was found between heart rate variability (a cardiovascular marker) and resting blood pressure. Secondly, this cardiovascular marker was also significantly affected by a single session of isometric exercise, an effect that persisted for at least 4 hours after exercise. However, thirdly, this marker and other cardiovascular markers (such as cardiac output and stroke volume) did not correlate with reductions in blood pressure seen after 4 weeks of isometric training. Instead, the training-induced reductions in blood pressure correlated strongly with neuromuscular and metabolic markers of isometric training. The extent to which local muscle fatigue was induced during isometric training correlated with the reductions in resting blood pressure. Therefore (a) isometric training intensity appears to be of utmost importance in the reductions in resting blood pressure (when bilateral-leg exercise is performed in 2 minute bouts), and (b) the mechanism whereby the adaptations in resting blood pressure occur is best reflected in neuromuscular and metabolic markers of local muscle fatigue during that training. These findings are discussed with a particular focus on the possible role of muscle metaboreceptor stimulation, during isometric training in the mechanism of training-induced reduction in resting blood pressure.
Author: Linda S. Pescatello Publisher: Springer ISBN: 3319170767 Category : Medical Languages : en Pages : 347
Book Description
As the first primer on the effects of exercise on human hypertension, Effects of Exercise on Hypertension: From Cells to Physiological Systems provides the state-of-the-art effects of exercise on the many possible mechanisms underlying essential hypertension in humans. The book contains chapters by distinguished experts on the effects of exercise on physiological systems known to be involved in hypertension development and maintenance as well as less well known aspects of hypertension such as 24-hour ambulatory blood pressure profile and oxidative stress. An emerging area, the effects of resistance exercise training on blood pressure is also covered. A unique aspect of the book is that it covers the effects of exercise mimetics on vascular cell adaptations in order to begin to elucidate some of the cellular mechanisms that may underlie blood pressure reductions with exercise training. Lastly, the book will end with a chapter on the interactive effects of genes and exercise on blood pressure. Chapters are grouped by physiological system or mechanism. The text begins with two overview chapters; one on the general effects of aerobic exercise training and the second on the general effects of resistance exercise training on blood pressure. Each chapter begins with a bulleted list of key points. Effects of Exercise on Hypertension: From Cells to Physiological Systems will be of great value to professional individuals in cardiovascular medicine, the cardiovascular sciences, allied health care professionals, and medical and graduate students in the cardiovascular sciences and medicine.
Author: Kyle Francis Gill Publisher: ISBN: Category : Languages : en Pages : 94
Book Description
Introduction. Isometric exercise training (IET) is becoming established as an effective method for reducing resting blood pressure (RBP); however, the effect of different exercise intensities on RBP is not well understood. IET protocol development will allow for implementation of the most effective IET programs for reducing RBP. The primary purpose of this study was to compare the effects of two different leg isometric exercise intensities on RBP and heart rate (HR). A secondary aim of this study was to establish an IET intensity threshold at which a significant reduction in RBP occurs. Methods. Thirty-five participants were recruited for this study and randomly selected to the control, high intensity (Tl), or low intensity (T2) training group for three weeks. The participants performed four sets of two minute bi-lateral isometric exercise bouts, three days per week. RBP (mean ± SE) was measured prior to training each session. Results. The T2 group showed significant reductions from pre- to post-training of -3.6 ± 1.03 mmHg in systolic blood pressure, -4.0 ± 0.99 mmHg in diastolic blood pressure, and -3.9 ± 0.99 mmHg in mean arterial pressure. HR was reduced significantly in the T2 training group (-1.33 ± 1.06 bpm, P=0.045). These variables did not show any significant reductions in the control or the Tl groups. Conclusions. These findings show that RBP can be significantly reduced after performing bi-lateral leg isometric exercise training at 30% EMGpeak, but not at 20% EMGpeak. Therefore, the IET intensity threshold lies between 20 and 30% EMGpeak.
Author: Michitoshi Inoue Publisher: Springer Science & Business Media ISBN: 4431683674 Category : Medical Languages : en Pages : 330
Book Description
Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.
Author: Michael J. Joyner Publisher: Perspectives Cshl ISBN: 9781621821656 Category : Medical Languages : en Pages : 408
Book Description
Exercise training provokes widespread transformations in the human body, requiring coordinated changes in muscle composition, blood flow, neuronal and hormonal signaling, and metabolism. These changes enhance physical performance, improve mental health, and delay the onset of aging and disease. Understanding the molecular basis of these changes is therefore important for optimizing athletic ability and for developing drugs that elicit therapeutic effects. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines the biological basis of exercise from the molecular to the systemic levels. Contributors discuss how transcriptional regulation, cytokine and hormonal signaling, glucose metabolism, epigenetic modifications, microRNA profiles, and mitochondrial and ribosomal functions are altered in response to exercise training, leading to improved skeletal muscle, hippocampal, and cardiovascular function. Cross talk among the pathways underlying tissue-specific and systemic responses to exercise is also considered. The authors also discuss how the understanding of such molecular mechanisms may lead to the development of drugs that mitigate aging and disease. This volume will therefore serve as a vital reference for all involved in the fields of sports science and medicine, as well as anyone seeking to understand the molecular mechanisms by which exercise promotes whole-body health.
Author: G. Devereux
Author: G. Devereux
Author: Lucinda Jayne Howland
Author: Anthony W. Baross
Author: Linda S. Pescatello
Author: Jonathan Wiles
Author: Kyle Francis Gill
Author: Heidi Katherine Byrne
Author: Michitoshi Inoue
Author: Michael J. Joyner
Author: