Author: Mark Gregory Tagett
Publisher:
ISBN:
Category : Blood pressure
Languages : en
Pages : 312
Book Description
The Effects of Angiotensin II-induced Hypertension on the Baroreceptor Reflex
Author: Mark Gregory Tagett
Publisher:
ISBN:
Category : Blood pressure
Languages : en
Pages : 312
Book Description
Publisher:
ISBN:
Category : Blood pressure
Languages : en
Pages : 312
Book Description
Angiotensin II Receptor Blockade Physiological and Clinical Implications
Author: Naranjan S. Dhalla
Publisher: Springer Science & Business Media
ISBN: 1461557437
Category : Medical
Languages : en
Pages : 607
Book Description
The relationship between angiotensin II and hypertension was established in 1898 when angiotensin II was shown to modulate systemic blood pressure. Over the intervening decades, a complete characterization of the renin-angiotensin system (RAS) has been achieved, and our understanding of its biochemistry and physiology has led to the directed development of agents such ·as ACE inhibitors and receptor antagonists capable of controlling hypertension. More recently, it was shown that angiotensin II is secreted within certain tissues and that these tissue-specific systems operate independently of the systemic RAS. The novel concept that angiotensin II regulates a number of cardiovascular processes that are unrelated to blood pressure has renewed the interest of both basic and clinical scientists in angiotensin II. The association between angiotensin II and cardiac growth, in particular, has indicated that therapies currently in use for hypertension may have direct application to the treatment of heart failure. The Manitoba Cardiovascular Forum on Angiotensin Receptor Blockade in Winnipeg was convened October 18-20, 1996 to examine the clinical and basic aspects of angiotensin receptor biology as they apply to hypertension and heart failure. In addition, the potential treatment of these conditions using specific angio tensin receptor antagonists was addressed within the context of their immediate therapeutic application and future potential.
Publisher: Springer Science & Business Media
ISBN: 1461557437
Category : Medical
Languages : en
Pages : 607
Book Description
The relationship between angiotensin II and hypertension was established in 1898 when angiotensin II was shown to modulate systemic blood pressure. Over the intervening decades, a complete characterization of the renin-angiotensin system (RAS) has been achieved, and our understanding of its biochemistry and physiology has led to the directed development of agents such ·as ACE inhibitors and receptor antagonists capable of controlling hypertension. More recently, it was shown that angiotensin II is secreted within certain tissues and that these tissue-specific systems operate independently of the systemic RAS. The novel concept that angiotensin II regulates a number of cardiovascular processes that are unrelated to blood pressure has renewed the interest of both basic and clinical scientists in angiotensin II. The association between angiotensin II and cardiac growth, in particular, has indicated that therapies currently in use for hypertension may have direct application to the treatment of heart failure. The Manitoba Cardiovascular Forum on Angiotensin Receptor Blockade in Winnipeg was convened October 18-20, 1996 to examine the clinical and basic aspects of angiotensin receptor biology as they apply to hypertension and heart failure. In addition, the potential treatment of these conditions using specific angio tensin receptor antagonists was addressed within the context of their immediate therapeutic application and future potential.
Relationship Between Experimental Angiotensin II Induced Hypertension and Activation of the Endothelin System in Male Rats
Author: Jennifer Rebecca Ballew
Publisher:
ISBN:
Category : Angiotensin II
Languages : en
Pages : 462
Book Description
Publisher:
ISBN:
Category : Angiotensin II
Languages : en
Pages : 462
Book Description
Regulation of Blood Pressure by the Central Nervous System
Author: Michael Fernandes
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 520
Book Description
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 520
Book Description
Angiotensin II Receptor Antagonists
Author: Murray Epstein
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 408
Book Description
The recent development of several new, non-peptide, orally active angiotensin II receptor antagonists is revolutionizing the treatment of patients with hypertension and various cardiovascular disorders. In this book experts review the current state of angiotensin II antagonists and survey the progress of these diverse applications. Issues relating to angiotensin II and their receptors are examined in relation to their effects on the kidney, non-diabetic renal disease, heart disease, diabetes mellitus, and various other disorders. The combination of AT1 receptor antagonists with other antihypertensive agents is reviewed in depth. The clinical attributes of these drugs are complemented by in-depth reviews of the physiology and pharmacology of angiotensin II peptides. The authors present the most recent findings in ligand recognition, activation, signal coupling, desensitization and functional alterations of vessels, especially small arteries, in patients with hypertension. This book constitutes the only available compendium on the clinical and experimental features of angiotensin II receptor antagonists. The unique features of the rapidly emerging class of drugs are surveyed throughout. Contributions have been made from international experts who have personally contributed to the discovery and development of these novel drugs. Recent cutting-edge physiology and pharmacology studies by renowned international experts provide a platform for considering the clinical applications of these agents.
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 408
Book Description
The recent development of several new, non-peptide, orally active angiotensin II receptor antagonists is revolutionizing the treatment of patients with hypertension and various cardiovascular disorders. In this book experts review the current state of angiotensin II antagonists and survey the progress of these diverse applications. Issues relating to angiotensin II and their receptors are examined in relation to their effects on the kidney, non-diabetic renal disease, heart disease, diabetes mellitus, and various other disorders. The combination of AT1 receptor antagonists with other antihypertensive agents is reviewed in depth. The clinical attributes of these drugs are complemented by in-depth reviews of the physiology and pharmacology of angiotensin II peptides. The authors present the most recent findings in ligand recognition, activation, signal coupling, desensitization and functional alterations of vessels, especially small arteries, in patients with hypertension. This book constitutes the only available compendium on the clinical and experimental features of angiotensin II receptor antagonists. The unique features of the rapidly emerging class of drugs are surveyed throughout. Contributions have been made from international experts who have personally contributed to the discovery and development of these novel drugs. Recent cutting-edge physiology and pharmacology studies by renowned international experts provide a platform for considering the clinical applications of these agents.
Angiotensin II and Arterial Pressure Regulation in Hypertension
Author: Corinn Marie Pawloski
Publisher:
ISBN:
Category : Angiotensins
Languages : en
Pages : 384
Book Description
Publisher:
ISBN:
Category : Angiotensins
Languages : en
Pages : 384
Book Description
Chronic Effects of Angiotensin II at the Subfornical Organ-A Central Integration Site of Cardiovascular Homeostasis
Author: Michael David Hendel
Publisher:
ISBN:
Category :
Languages : en
Pages : 342
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 342
Book Description
Androgenic Effects on Angiotensin II-induced Blood Pressure and Cochlear Blood Flow Changes in Rats
Author: Angela Joanne Flynn
Publisher:
ISBN:
Category : Angiotensins
Languages : en
Pages : 94
Book Description
Publisher:
ISBN:
Category : Angiotensins
Languages : en
Pages : 94
Book Description
Angiotensin II - Neural Interactions in Cardiovascular Control
Author: John Peter Collister
Publisher:
ISBN:
Category :
Languages : en
Pages : 406
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 406
Book Description
The Role of the Slow Pressor Effect of Angiotensin II in the Development of Hypertension
Author: Vyvian Janet Gorbea-Oppliger
Publisher:
ISBN:
Category : Angiotensins
Languages : en
Pages : 334
Book Description
Publisher:
ISBN:
Category : Angiotensins
Languages : en
Pages : 334
Book Description