The Effect of High Protein Diets on Renal Hypertrophy in Rats Following Whole-body Irradiation PDF Download

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The Effect of High Protein Diets on Renal Hypertrophy in Rats Following Whole-body Irradiation

The Effect of High Protein Diets on Renal Hypertrophy in Rats Following Whole-body Irradiation PDF Author: Frank Konishi
Publisher:
ISBN:
Category : High-protein diet
Languages : en
Pages : 26

Book Description
The relationship between high protein intake and increase in kidney weight was investigated in rats exposed to a single dose of 375 rad X-irradiation. Attempts were made to characterize the degree of renal hypertrophy and hyperplasia nvolved by employing irradiation as an inhibitor of cellular proliferation. Rats were fed a high protein diet and exposed to irradiation at various points of the feeding regime. The high protein diet significantly increased kidney weight in all cases but the increase was not influenced by the X-ray dose employed, or time of administration. However, histological studies of the kidneys showed that irradiation reduced the incidences of abnormal tubular hyperplasia. The renal lesions also appeared much earlier than previously reported by other investigators. Rats fed high protein diets appeared to recover body weight loss from the irradiation at a faster rate than those fed a basal diet. A possible mechanism is briefly discussed. (Author).

The Effect of High Protein Diets on Renal Hypertrophy in Rats Following Whole-body Irradiation

The Effect of High Protein Diets on Renal Hypertrophy in Rats Following Whole-body Irradiation PDF Author: Frank Konishi
Publisher:
ISBN:
Category : High-protein diet
Languages : en
Pages : 26

Book Description
The relationship between high protein intake and increase in kidney weight was investigated in rats exposed to a single dose of 375 rad X-irradiation. Attempts were made to characterize the degree of renal hypertrophy and hyperplasia nvolved by employing irradiation as an inhibitor of cellular proliferation. Rats were fed a high protein diet and exposed to irradiation at various points of the feeding regime. The high protein diet significantly increased kidney weight in all cases but the increase was not influenced by the X-ray dose employed, or time of administration. However, histological studies of the kidneys showed that irradiation reduced the incidences of abnormal tubular hyperplasia. The renal lesions also appeared much earlier than previously reported by other investigators. Rats fed high protein diets appeared to recover body weight loss from the irradiation at a faster rate than those fed a basal diet. A possible mechanism is briefly discussed. (Author).

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Renal Hypertrophy and Function in Irradiated and Nephrectomized Rats Fed a High Protein Diet PDF Author: F. Konishi
Publisher:
ISBN:
Category : Kidneys
Languages : en
Pages : 30

Book Description


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Publisher: National Academies
ISBN: 0309039959
Category : Science
Languages : en
Pages : 436

Book Description
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