The Dangers of Cloning and the Promise of Regenerative Medicine PDF Download

Author: United States. Congress. Senate. Committee on Health, Education, Labor, and Pensions
Publisher:
ISBN:
Category : Human cloning
Languages : en
Pages : 68

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Author:
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ISBN:
Category :
Languages : en
Pages :

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Author: United States. Congress. Senate. Committee on the Judiciary
Publisher:
ISBN:
Category : Human cloning
Languages : en
Pages : 196

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Author: National Research Council
Publisher: National Academies Press
ISBN: 0309076374
Category : Science
Languages : en
Pages : 295

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Human reproductive cloning is an assisted reproductive technology that would be carried out with the goal of creating a newborn genetically identical to another human being. It is currently the subject of much debate around the world, involving a variety of ethical, religious, societal, scientific, and medical issues. Scientific and Medical Aspects of Human Reproductive Cloning considers the scientific and medical sides of this issue, plus ethical issues that pertain to human-subjects research. Based on experience with reproductive cloning in animals, the report concludes that human reproductive cloning would be dangerous for the woman, fetus, and newborn, and is likely to fail. The study panel did not address the issue of whether human reproductive cloning, even if it were found to be medically safe, would beâ€"or would not beâ€"acceptable to individuals or society.

Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309170427
Category : Science
Languages : en
Pages : 112

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Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.

Author: Ed Gaskin
Publisher: CreateSpace
ISBN: 9781500523718
Category : Science
Languages : en
Pages : 142

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“First Genetically Modified Babies Born,” read the news headline. While not technically examples of genetically modified humans, the fact is when the babies were genetically fingerprinted they had the genes from two mothers and one father, which would alarm most people. One of the scientists involved said this is child's play, a mere “tweaking” of the reproductive process. Imagine before you Tinker Toys or Legos of all different sizes, shapes and colors. Imagine those pieces are actually genes from insects, plants, animals and people that can be used interchangeably to provide humans characteristics only comic book superheroes possess. Scientists have already taken the gene that provides the jellyfish its green color and inserted it into the DNA of a white rabbit to create a "green rabbit." Scientists have taken the genes that enable spiders to make webbing and combined them with a goat's DNA as a way for the goat to make "spider silk”, a strong new fiber. We can do similar things with human DNA. Genomics provides us the equivalent of the "Application Program Interface” (API) for each human. Genomics, genetic engineering, embryonic stem cells, and nuclear transfer (cloning) independently have great promise and peril for us. There are numerous similarities between computer programing and “genetic programing” or genetic modification. Instead of programing with zero's and one's, we use C, T, A, G. We can reprogram DNA, cells and genes. The excitement with these new technologies is we can more effectively treat chronic diseases such as Parkinson's disease, osteoarthritis, osteoporosis, age-related macular degeneration, and atherosclerosis, which accounts for over 75% of medical costs. There are over 3,000 genetic diseases such as sickle cell anemia we could treat. We could treat infectious diseases such as HIV by developing an HIV resistant immune system. However, there are also dangers. The same way computers and software can be hacked, genetic structures can be hacked. Genetic “doping” is possible. Because of the similarity between digital and genetic technologies, much of what we learned in the digital revolution can be transferred to the application of genetic modification and regenerative medicine. This similarity and the potential applications have not escaped the attention of companies such as Google who have announced major investments in these areas and are prepared to spend in the hundreds of millions for research. As a result of these powerful technologies we are on the brink of a genetic revolution similar in size and scope to the digital revolution (think biological versions of Google, Amazon, and Apple, but without any rules or guidelines). Because of the similarity, this revolution will occur faster, as many of the lessons learned in the digital revolution will be applied to the genetic revolution, and there is an abundance of venture capital looking for these types of game changing, disruptive technologies.Developing new genetic applications might be similar to developing cell phone apps sold at the iTunes store. These new technologies are patentable and potentially worth billions of dollars. We should not trust industry to do the right thing. There is a need to have as much discussion on the genetic modification of humans as we do on the GMO labeling of food. Currently we lack a national discussion, legislation or regulatory guidance on these controversial topics. We have not had a national discussion on bioethics since we debated the use of embryonic stem cells and cloning, over a decade ago. This book reviews the religious and scientific arguments, and refines the work of Norman Ford who was writing in the context of reproductive technologies, not the debates concerning embryonic stem cells and therapeutic cloning, and looks at where we are headed, with a focus on Dr. Michael West, a thought leader in this area.

Author: Harold Varmus
Publisher: W. W. Norton & Company
ISBN: 9780393061284
Category : Biography & Autobiography
Languages : en
Pages : 354

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The nobel prize winning scientist and former director of the National Institue of Health recalls the events of his life and career in science, in an autobiography that also incorporates scientific information about cancer biology and issues in public health.

Author: Anthony Atala
Publisher: Academic Press
ISBN: 0123814235
Category : Science
Languages : en
Pages : 1203

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Book Description
Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. - Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology - The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine - New discoveries from leading researchers on restoration of diseased tissues and organs

Author: The President's Council on Bioethics
Publisher: Createspace Independent Publishing Platform
ISBN: 9781508822318
Category :
Languages : en
Pages : 0

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The prospect of human cloning burst into the public consciousness in 1997, following the announcement of the successful cloning of Dolly the sheep. It has since captured much attention and generated great debate, both in the United States and around the world. Many are repelled by the idea of producing children who would be genetically virtually identical to preexisting individuals, and believe such a practice unethical. But some see in such cloning the possibility to do good for infertile couples and the broader society. Some want to outlaw it, and many nations have done so. Others believe the benefits outweigh the risks and the moral concerns, or they oppose legislative interference with science and technology in the name of freedom and progress. Complicating the national dialogue about human cloning is the isolation in 1998 of human embryonic stem cells, which many scientists believe to hold great promise for understanding and treating many chronic diseases and conditions. Some scientists also believe that stem cells derived from cloned human embryos, produced explicitly for such research, might prove to be uniquely useful for studying many genetic diseases and devising novel therapies. Public reaction to this prospect has been mixed, with some Americans supporting it in the hope of advancing biomedical research and helping the sick and the suffering, while others are concerned about the instrumentalization or abuse of nascent human life and the resulting danger of moral insensitivity and degradation.

Author: Mohammed Ali Al-Bar
Publisher: Springer
ISBN: 3319184288
Category : Medical
Languages : en
Pages : 273

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This book discusses the common principles of morality and ethics derived from divinely endowed intuitive reason through the creation of al-fitr' a (nature) and human intellect (al-‘aql). Biomedical topics are presented and ethical issues related to topics such as genetic testing, assisted reproduction and organ transplantation are discussed. Whereas these natural sources are God’s special gifts to human beings, God’s revelation as given to the prophets is the supernatural source of divine guidance through which human communities have been guided at all times through history. The second part of the book concentrates on the objectives of Islamic religious practice – the maqa' sid – which include: Preservation of Faith, Preservation of Life, Preservation of Mind (intellect and reason), Preservation of Progeny (al-nasl) and Preservation of Property. Lastly, the third part of the book discusses selected topical issues, including abortion, assisted reproduction devices, genetics, organ transplantation, brain death and end-of-life aspects. For each topic, the current medical evidence is followed by a detailed discussion of the ethical issues involved.