The Core Model PDF Download

Author: A. Dodd
Publisher: Cambridge University Press
ISBN: 0521285305
Category : Mathematics
Languages : en
Pages : 269

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Book Description
This book aims to introduce the core model to those with a basic knowledge of axiomatic set theory. The covering lemma for K is the main technical result but other applications are also considered.

Author: Ibis Sanchez Serrano
Publisher: Academic Press
ISBN: 0128142944
Category : Medical
Languages : en
Pages : 176

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Book Description
The Core Model: A Collaborative Paradigm for the Pharmaceutical Industry and Global Health Care develops the innovative core model, an organizational research and design paradigm and economic theory that proposes a collaborative approach to resolving global health issues and improving the productivity of drug development. The model proposes that scientific collaboration does not occur in an unstructured manner, but actually takes place within a highly structured order where knowledge is transferred, integrated and finally translated into commercial products. An understanding of this model will help solve the global pharmaceutical industry ́s productivity problems and address important global health care and economic issues. This book is useful to researchers, advanced students, regulators, and management in pharmaceutical industries, as well as healthcare professionals, those working in health economics, and those interested in scientific innovation processes. - Explores the current state-of-the-art in the pharmaceutical industry and the global healthcare sector - Includes insights from world-leading figures in the pharmaceutical industry, healthcare sector, federal funding agencies, regulatory bodies, investment sector, entrepreneurship, intellectual property law, philanthropic organizations, and advocacy groups - Develops in-depth, original concepts, which have important implications in the understanding of, and search for, potential solutions to the world ́s health care crisis

Author: John R. Steel
Publisher: Cambridge University Press
ISBN: 1107167965
Category : Mathematics
Languages : en
Pages : 119

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Book Description
Suitable for graduate students and researchers in set theory, this volume develops a method for constructing core models that have Woodin cardinals.

Author: Lester G. Telser
Publisher: Routledge
ISBN: 0415701449
Category : Business & Economics
Languages : en
Pages : 390

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Book Description
In this key title, Lester Telser, the world's core theorist, explores several distinct areas to skilfully bring the ideas of core theory to bear on a range of issues within economics - with particular emphasis on supply and demand and the way markets function.

Author: Jeff Johnson
Publisher: Springer Nature
ISBN: 3031021959
Category : Computers
Languages : en
Pages : 96

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Book Description
People make use of software applications in their activities, applying them as tools in carrying out tasks. That this use should be good for people--easy, effective, efficient, and enjoyable--is a principal goal of design. In this book, we present the notion of Conceptual Models, and argue that Conceptual Models are core to achieving good design. From years of helping companies create software applications, we have come to believe that building applications without Conceptual Models is just asking for designs that will be confusing and difficult to learn, remember, and use. We show how Conceptual Models are the central link between the elements involved in application use: people's tasks (task domains), the use of tools to perform the tasks, the conceptual structure of those tools, the presentation of the conceptual model (i.e., the user interface), the language used to describe it, its implementation, and the learning that people must do to use the application. We further show that putting a Conceptual Model at the center of the design and development process can pay rich dividends: designs that are simpler and mesh better with users' tasks, avoidance of unnecessary features, easier documentation, faster development, improved customer uptake, and decreased need for training and customer support. Table of Contents: Using Tools / Start with the Conceptual Model / Definition / Structure / Example / Essential Modeling / Optional Modeling / Process / Value / Epilogue

Author: Frank Budinsky
Publisher: Addison-Wesley Professional
ISBN: 9780131425422
Category : Computers
Languages : en
Pages : 712

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Book Description
bull; Shows how EMF unifies three important technologies: Java, XML, and UML bull; Provides a comprehensive overview of the EMF classes including a complete quick reference for all the classes and methods in the EMF 1.1 API bull; Includes examples of many common framework customizations and programming techniques

Author: A. Dodd
Publisher: Cambridge University Press
ISBN: 9780511600586
Category : Mathematics
Languages : en
Pages : 0

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Book Description
The core model, K, is a generalization of Gödel's constructible universe of set theory; K is used to produce 'fine structural' results of a less restrictive kind. This book aims to introduce the core model to those with a basic knowledge of axiomatic set theory. The covering lemma for K is the main technical result but other applications are also considered. The author gives a full exposition of general fine structure and of iterated ultrapowers and concludes the work with a short section on the difficulties encountered in constructing more general core models using 'extenders'.

Author: Martin Bertau
Publisher: John Wiley & Sons
ISBN: 9783527316991
Category : Science
Languages : en
Pages : 544

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Book Description
This first comprehensive survey to cover all pharmaceutically relevant topics provides a comprehensive introduction to this novel and revolutionary tool, presenting both concepts and application examples of biosimulated cells, organs and organisms. Following an introduction to the role of biosimulation in drug development, the authors go on to discuss the simulation of cells and tissues, as well as simulating drug action and effect. A further section is devoted to simulating networks and populations, and the whole is rounded off by a look at the potential for biosimulation in industrial drug development and for regulatory decisions. Part of the authors are members of the BioSim Network of Excellence that encompasses more than 40 academic institutions, pharmaceutical companies and regulatory authorities dealing with drug development; other contributors come from industry, resulting in a cross-disciplinary expert reference.

Author: S. M. Niaz Arifin
Publisher: John Wiley & Sons
ISBN: 1118964373
Category : Medical
Languages : en
Pages : 324

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Book Description
Presents an overview of the complex biological systems used within a global public health setting and features a focus on malaria analysis Bridging the gap between agent-based modeling and simulation (ABMS) and geographic information systems (GIS), Spatial Agent-Based Simulation Modeling in Public Health: Design, Implementation, and Applications for Malaria Epidemiology provides a useful introduction to the development of agent-based models (ABMs) by following a conceptual and biological core model of Anopheles gambiae for malaria epidemiology. Using spatial ABMs, the book includes mosquito (vector) control interventions and GIS as two example applications of ABMs, as well as a brief description of epidemiology modeling. In addition, the authors discuss how to most effectively integrate spatial ABMs with a GIS. The book concludes with a combination of knowledge from entomological, epidemiological, simulation-based, and geo-spatial domains in order to identify and analyze relationships between various transmission variables of the disease. Spatial Agent-Based Simulation Modeling in Public Health: Design, Implementation, and Applications for Malaria Epidemiology also features: Location-specific mosquito abundance maps that play an important role in malaria control activities by guiding future resource allocation for malaria control and identifying hotspots for further investigation Discussions on the best modeling practices in an effort to achieve improved efficacy, cost-effectiveness, ecological soundness, and sustainability of vector control for malaria An overview of the various ABMs, GIS, and spatial statistical methods used in entomological and epidemiological studies, as well as the model malaria study A companion website with computer source code and flowcharts of the spatial ABM and a landscape generator tool that can simulate landscapes with varying spatial heterogeneity of different types of resources including aquatic habitats and houses Spatial Agent-Based Simulation Modeling in Public Health: Design, Implementation, and Applications for Malaria Epidemiology is an excellent reference for professionals such as modeling and simulation experts, GIS experts, spatial analysts, mathematicians, statisticians, epidemiologists, health policy makers, as well as researchers and scientists who use, manage, or analyze infectious disease data and/or infectious disease-related projects. The book is also ideal for graduate-level courses in modeling and simulation, bioinformatics, biostatistics, public health and policy, and epidemiology.

Author: Eckhard D. Falkenberg
Publisher: Springer
ISBN: 0387348700
Category : Computers
Languages : en
Pages : 327

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Book Description
This is a compilation of papers presented at the Information System Concepts conference in Marburg, Germany. The special focus is consolidation and harmonisation of the numerous and widely diverging views in the field of information systems. This issue has become a hot topic, as many leading information system researchers and practitioners come to realise the importance of better communication among the members of the information systems community, and of a better scientific foundation of this rapidly evolving field.