Author: Zvi Rappoport
Publisher: John Wiley & Sons
ISBN: 047086401X
Category : Science
Languages : en
Pages : 1266
Book Description
The Chemistry of Cyclobutanes provides an in depth and comprehensive review of cyclobutanes and includes chapters on the theoretical and computational foundations; on analytical and spectroscopical aspects with dedicated chapters on Mass Spectrometry, NMR and IR/UV. There are also extensive application examples enabling the reader to collect both a theoretical and practical understanding. The Chemistry of Functional Groups Series was originally founded by Saul Patai (1918-1998) and in the 39 years of publishing has produced more than 100 volumes, providing outstanding reviews on all aspects of functional groups including analytical, physical and synthetic and applied chemistry. Saul Patai has been helped by outstanding editors, especially Zvi Rappoport who has now taken responsibility for the series to continue the tradition of producing high quality reviews with editors such as Y. Apeloig, I. Marek and J. Liebman.
The Chemistry of Cyclobutanes
The Chemistry of Cyclobutane Derivatives
Author: Bob G. Gower
Publisher:
ISBN:
Category : Cyclobutenone
Languages : en
Pages : 82
Book Description
Publisher:
ISBN:
Category : Cyclobutenone
Languages : en
Pages : 82
Book Description
The chemistry of cyclobutane compounds
Author: Carolyn Mary Sweeny
Publisher:
ISBN:
Category : Alicyclic compounds
Languages : en
Pages : 164
Book Description
Publisher:
ISBN:
Category : Alicyclic compounds
Languages : en
Pages : 164
Book Description
The Chemistry of Cyclobutanes
Author: Zvi Rappoport
Publisher:
ISBN:
Category : Cyclobutane
Languages : en
Pages : 640
Book Description
Publisher:
ISBN:
Category : Cyclobutane
Languages : en
Pages : 640
Book Description
Some Aspects of the Chemistry of Cyclobutane (Pt. 1) ; Investigations on Some Natural Products (Pt. 2).
Synthesis and Reactivity of Donor-Acceptor Substituted Aminocyclopropanes and Aminocyclobutanes
Author: Florian de Nanteuil
Publisher: Springer
ISBN: 3319230069
Category : Science
Languages : en
Pages : 329
Book Description
This thesis presents a general approach to accessing nitrogen-substituted hetero- and carbocycles. In short, the annulation reactions developed in the thesis make it possible to access nitrogen-substituted four-, five- and six-membered rings, all essential building blocks for the synthesis of bioactive molecules. Many natural products display a saturated polycyclic core allowing a well-defined arrangement of functional groups in space. As such, they can interact with biological targets with a high degree of affinity and selectivity, surpassing many synthetic drugs. Nevertheless, the efficient synthesis of such complex ring systems poses a challenge for organic chemistry. Through careful tuning of the electronic properties of a nitrogen donor group and a diester acceptor group, the first [3+2] annulation reaction between aminocyclopropanes and enol ethers or carbonyl compounds is now possible. The reaction proceeded under mild catalytic conditions, and the building blocks obtained can be found at the core of bioactive alkaloids, drugs such as Ramipril and biomolecules such as DNA and RNA. Thanks to the dynamic kinetic asymmetric annulation of aminocyclopropanes with enol ethers and aldehydes, access to enantioenriched compounds is also now possible. Lastly, a synthesis of donor-acceptor aminocyclobutanes via [2+2] cycloaddition using a cheap iron catalyst was developed, allowing them to be used in [4+2] annulations to access cyclohexylamines.
Publisher: Springer
ISBN: 3319230069
Category : Science
Languages : en
Pages : 329
Book Description
This thesis presents a general approach to accessing nitrogen-substituted hetero- and carbocycles. In short, the annulation reactions developed in the thesis make it possible to access nitrogen-substituted four-, five- and six-membered rings, all essential building blocks for the synthesis of bioactive molecules. Many natural products display a saturated polycyclic core allowing a well-defined arrangement of functional groups in space. As such, they can interact with biological targets with a high degree of affinity and selectivity, surpassing many synthetic drugs. Nevertheless, the efficient synthesis of such complex ring systems poses a challenge for organic chemistry. Through careful tuning of the electronic properties of a nitrogen donor group and a diester acceptor group, the first [3+2] annulation reaction between aminocyclopropanes and enol ethers or carbonyl compounds is now possible. The reaction proceeded under mild catalytic conditions, and the building blocks obtained can be found at the core of bioactive alkaloids, drugs such as Ramipril and biomolecules such as DNA and RNA. Thanks to the dynamic kinetic asymmetric annulation of aminocyclopropanes with enol ethers and aldehydes, access to enantioenriched compounds is also now possible. Lastly, a synthesis of donor-acceptor aminocyclobutanes via [2+2] cycloaddition using a cheap iron catalyst was developed, allowing them to be used in [4+2] annulations to access cyclohexylamines.
Chemistry of Radicals Derived from the Fragmentation of Cyclobutane Ring
Author: Anusorn Vorasingha
Publisher:
ISBN:
Category : Cyclobutanes
Languages : en
Pages : 208
Book Description
Publisher:
ISBN:
Category : Cyclobutanes
Languages : en
Pages : 208
Book Description
An Investigation Into the Chemistry of Halogenated Cyclobutanes and Cyclobutenes
Author: Thomas Stone Croft
Publisher:
ISBN:
Category : Butane
Languages : en
Pages : 192
Book Description
Publisher:
ISBN:
Category : Butane
Languages : en
Pages : 192
Book Description
Investigations in Cyclobutane Chemistry
Section I, Synthesis and Properties of Fused Cyclobutanes
Author: Robert Lee Petty
Publisher:
ISBN:
Category : Butterflies
Languages : en
Pages : 244
Book Description
Publisher:
ISBN:
Category : Butterflies
Languages : en
Pages : 244
Book Description