The Chemistry and Biology of Sialic Acids and Related Substances PDF Download

Author: Alfred Gottschalk
Publisher: CUP Archive
ISBN:
Category :
Languages : en
Pages : 148

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Author: Roland Schauer
Publisher: Springer Science & Business Media
ISBN: 3709186803
Category : Science
Languages : en
Pages : 357

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Book Description
Rapid progress in the field of sialic acids has made it desirable to collect the new data about these unique sugars and to continue the series of books on this topic. In 1960, A. GOTTSCHALK wrote "The Chemistry and Biology of Sialic Acids and Related Substances" (Cambridge University Press) and in 1976, A. ROSENBERG and C. -L. SCHENGRUND published "Biological Roles of Sialic Acids" (Plenum Press). In this book emphasis is given to various modern methods used in the isolation and analysis of sialic acids. New approaches to the synthesis of free and bound sialic acids are described and the vast field of occurrence and metabolism of these substances is reviewed. Sialidoses are dealt with in one of the chapters, because sialidases have been recognized as factors of pathophysiological im portance. As knowledge is increasing about the involvement of sialic acids in many aspects of cell biology, another chapter is devoted to these phenomena. With this book I intend to demonstrate modern trends in sialic acid chemistry and biochemistry, and I hope that it will be of practical use and find its place in laboratories rather than in libraries. This publication offers an opportunity to thank all colleagues in many countries, including my coworkers at the universities of Bochum and Kiel, for their cooperation, stimulating discussions and, very important, useful criticism. The continuous cooperation with J. F. G. VLIEGENTHART and his coworkers, Utrecht, has been rewarding in many respects.

Author: Roland Schauer
Publisher: Springer My Copy UK
ISBN: 9783709186817
Category :
Languages : en
Pages : 370

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Book Description

Author: Abraham Rosenberg
Publisher: Springer Science & Business Media
ISBN: 146842226X
Category : Science
Languages : en
Pages : 386

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Book Description
There is a startling amount of research activity concerning the role of sialic acid in mammalian cells and in the mammalian organism. One may discern in the early literature premonitions of compounds containing sialic acid, traceable by descriptions of color reactions, as far back as the turn of the century. Work spanning the 1930s to the 1950s culmi nated in the crystallization of sialic acid from a wide variety of biological materials. The ubiquitous nature of the sialic acids, and the biological importance of the substances in which they occur, then became generally manifest. Since then, the chemistry and metabolism of sialic acid and its occurrence, notably, but not exclusively, in the outer cell surfaces of mammalian cells and in key extracellular glycoproteins, have received great attention. The involvement of sialic acid-containing substances in tumorigenicity and in numerous metabolic and infectious pathological conditions, and in the growth, development, and integrity of mammalian cells has achieved widespread recognition. Intensive inquiry into the biological roles of sialic acid continues in a large number of research laboratories throughout the world. This book is intended to represent for the uninitiated as well as for the expert a wide and detailed overview of the current state of knowledge. Major efforts and pioneering break throughs have emerged from several laboratories, located on both sides of the Atlantic, of which we make no special individual mention here since they will to some extent appear in the pages that follow.

Author: Ajit Varki
Publisher: CSHL Press
ISBN: 9780879696818
Category : Medical
Languages : en
Pages : 694

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Book Description
Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.

Author: David C. Baker
Publisher: Academic Press
ISBN: 0128171480
Category : Science
Languages : en
Pages : 193

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Book Description
Sialic Acids, Volume 76, the most recent release in the Advances in Carbohydrate Chemistry and Biochemistry series, is the second volume of a two-volume set devoted to the sialic acids. Vol. 76, devoted to the biological and biomedical aspects of sialic acids, includes chapters on "Sialic Acids in Neurology," "Sialic Acids in Nonenveloped Virus Infections," and "The Biology of Gangliosides," all written by leading experts in their fields. Features contributions from leading authorities and industry experts who specialize in carbohydrate chemistry, biochemistry and research Integrates the industrial, analytical and technological aspects of biochemistry, organic chemistry and instrumentation methodology in the study of carbohydrates Informs and updates on all the latest developments in the field

Author: A. Rosenberg
Publisher: Springer Science & Business Media
ISBN: 9780306449741
Category : Medical
Languages : en
Pages : 398

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Book Description
Abraham Rosenberg assembles the groundbreaking work of preeminent international scientists to provide the most current, state-of-the-art presentation of research in siabiology. This concise volume examines the historical development of the field and reviews current knowledge on the genetic, immunologic, oncologic, neurodevelopmental, pathogenic, and cell regulatory properties of sialic acid. Outstanding features of this work include exhaustive reference material and detailed information tables.

Author: Rita Gerardy-Schahn
Publisher: Springer
ISBN: 3319213172
Category : Science
Languages : en
Pages : 261

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Book Description
The series Topics in Current Chemistry presents critical reviews of the present and future trends in modern chemical research. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field. Review articles for the individual volumes are invited by the volume editors. Readership: research chemists at universities or in industry, graduate students.

Author: Alfred Gottschalk
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 144

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Book Description

Author:
Publisher: Academic Press
ISBN: 0128155361
Category : Science
Languages : en
Pages : 364

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Book Description
Sialic Acids, Volume 75, the latest release in the Advances in Carbohydrate Chemistry and Biochemistry series provides critical and informative articles written by research specialists that integrate the industrial, analytical and technological aspects of biochemistry, organic chemistry and instrumentation methodology to the study of carbohydrates. The series' articles present a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry, with this release covering The Early Exploration of the Sialic Acid World, Sialic Acid Chemistry, Sialic Acids in Evolution and Ontogenesis, Sialic Acids in Neurology, Sialic Acids in Cancer Biology, Sialic Acids in Virology, and more. Features contributions from leading authorities and industry experts who specialize in carbohydrate chemistry, biochemistry and research Integrates the industrial, analytical and technological aspects of biochemistry, organic chemistry and instrumentation methodology in the study of carbohydrates Informs and updates on all the latest developments in the field