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Author: Tess Gerritsen Publisher: Simon and Schuster ISBN: 1439140782 Category : Fiction Languages : en Pages : 518
Book Description
With her acclaimed novels Harvest and Life Support, Tess Gerritsen has injected a powerful dose of adrenaline into the medical thriller. Now, Gerritsen melds page-turning suspense with chilling realism as a small-town doctor races to unravel the roots of a violent outbreak—before it destroys everything she loves. Lapped by the gentle waters of Locust Lake, the small resort town of Tranquility, Maine, seems like the perfect spot for Dr. Claire Elliot to shelter her adolescent son, Noah, from the distractions of the big city and the lingering memory of his father's death. But with the first snap of winter comes shocking news that puts her practice on the line: a teenage boy under her care has committed an appalling act of violence. And as Claire and all of Tranquility soon discover, it is just the start of a chain of lethal outbursts among the town's teenagers. As the rash of disturbing behavior grows, Claire uncovers a horrifying secret: this is not the first time it has happened. Twice a century, the children of Tranquility lash out with deadly violence. Claire suspects that there is a biological cause for the epidemic, and she fears that the placid Locust Lake may conceal an insidious danger. As she races to save Tranquility—and her son—from harm, Claire discovers an even greater threat: a shocking conspiracy to manipulate nature and cause innocents to slaughter.
Author: Tess Gerritsen Publisher: Simon and Schuster ISBN: 1439140782 Category : Fiction Languages : en Pages : 518
Book Description
With her acclaimed novels Harvest and Life Support, Tess Gerritsen has injected a powerful dose of adrenaline into the medical thriller. Now, Gerritsen melds page-turning suspense with chilling realism as a small-town doctor races to unravel the roots of a violent outbreak—before it destroys everything she loves. Lapped by the gentle waters of Locust Lake, the small resort town of Tranquility, Maine, seems like the perfect spot for Dr. Claire Elliot to shelter her adolescent son, Noah, from the distractions of the big city and the lingering memory of his father's death. But with the first snap of winter comes shocking news that puts her practice on the line: a teenage boy under her care has committed an appalling act of violence. And as Claire and all of Tranquility soon discover, it is just the start of a chain of lethal outbursts among the town's teenagers. As the rash of disturbing behavior grows, Claire uncovers a horrifying secret: this is not the first time it has happened. Twice a century, the children of Tranquility lash out with deadly violence. Claire suspects that there is a biological cause for the epidemic, and she fears that the placid Locust Lake may conceal an insidious danger. As she races to save Tranquility—and her son—from harm, Claire discovers an even greater threat: a shocking conspiracy to manipulate nature and cause innocents to slaughter.
Author: Roland N. Pittman Publisher: Biota Publishing ISBN: 1615047212 Category : Medical Languages : en Pages : 117
Book Description
This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Author: Institute of Medicine Publisher: National Academies Press ISBN: 0309082587 Category : Medical Languages : en Pages : 172
Book Description
This report from the Committee on Military Nutrition Research reviews the history of caffeine usage, the metabolism of caffeine, and its physiological effects. The effects of caffeine on physical performance, cognitive function and alertness, and alleviation of sleep deprivation impairments are discussed in light of recent scientific literature. The impact of caffeine consumption on various aspects of health, including cardiovascular disease, reproduction, bone mineral density, and fluid homeostasis are reviewed. The behavioral effects of caffeine are also discussed, including the effect of caffeine on reaction to stress, withdrawal effects, and detrimental effects of high intakes. The amounts of caffeine found to enhance vigilance and reaction time consistently are reviewed and recommendations are made with respect to amounts of caffeine appropriate for maintaining alertness of military personnel during field operations. Recommendations are also provided on the need for appropriate labeling of caffeine-containing supplements, and education of military personnel on the use of these supplements. A brief review of some alternatives to caffeine is also provided.
Author: Carlos Franco-Paredes Publisher: Academic Press ISBN: 0128044802 Category : Medical Languages : en Pages : 246
Book Description
Core Concepts in Clinical Infectious Diseases (CCCID) provides medical students and researchers, infectious disease fellows, and practicing clinicians with key clinical concepts in the differential diagnosis and workup of infectious diseases. With the use of tables, charts, and problem-oriented medical diagnosis, it will provide a way of organizing and thinking about commonly seen clinical presentations of infectious diseases. Instead of discussing each disease process or any particular infectious process, this book will assist clinicians in seeing the forest and not focusing on the leaf. Graphs and tables have been constructed over 14 years of taking notes, teaching clinical infectious diseases, and discussing real clinical cases. This book is not about acquiring the structure of infectious diseases that is presented in classic textbooks of infectious disease; instead, it is about refining the process of putting the pieces together in clinical thinking to achieve an accurate clinical diagnosis and thus improved patient care. - Assists the reader in connecting the dots (process of accumulating real-time knowledge) during the thinking process of clinical decision-making in the area of infectious diseases - Uses tables and charts for easy understanding and application - Contains a manual style that targets different audiences, such as medical students, hospital medicine specialists, outpatient internal medicine practitioners, infectious disease fellows in training, and practicing clinicians - Provides an up-to-date discussion of core concepts in clinical infectious diseases
Author: Wm. Michael Dunne, Jr. Publisher: John Wiley & Sons ISBN: 1555819826 Category : Medical Languages : en Pages : 335
Book Description
In the clinical microbiology laboratory, blood is a critical diagnostic sample that, in the majority of cases is sterile (or is it?). However, when microbes gain access to and multiply in the bloodstream, it can result in life-threatening illness including sepsis. Mortality rates from bloodstream infection and sepsis range from 25% to 80%, killing millions of people annually. Blood cultures are a vital technology used in the microbiology laboratory to isolate and identify microbes and predict their response to antimicrobial therapy. The Dark Art of Blood Cultures, edited by Wm. Michael Dunne, Jr., and Carey-Ann D. Burnham, surveys the entire field of blood culture technology, providing valuable information about every phase of the process, from drawing samples to culture methods to processing positive cultures. The Dark Art of Blood Cultures is organized around several major topics. History of blood culture methods. Details the timeline of blood culture methods from manual through automated and describes the technological development of the leading automated blood culture systems (Bactec, BacT/Alert, and VersaTREK). Manual and automated blood culture methods. Critiques manual and automated methods for setting up blood cultures for adult and pediatric patients. Detection of pathogens directly from blood specimens. Describes currently available CE marked and FDA-cleared commercial tests using both phenotypic and genotypic markers, including their strengths and limitations. The workflow of culturing blood. Includes best practices from specimen collection to culture system verification, processing positive cultures for microbe identification and antibiotic susceptibility determination, along with the epidemiology of positive blood cultures and the value of postmortem blood cultures. Microorganisms in the blood. Examines the concept of a blood microbiome in healthy and diseased individuals. The Dark Art of Blood Cultures is a resource that clinicians, laboratorians, lab directors, and hospital administrators will find engaging and extremely useful.
Author: Nancy L. Moureau Publisher: Springer ISBN: 3030031497 Category : Medical Languages : en Pages : 303
Book Description
This Open access book offers updated and revised information on vessel health and preservation (VHP), a model concept first published in poster form in 2008 and in JVA in 2012, which has received a great deal of attention, especially in the US, UK and Australia. The book presents a model and a new way of thinking applied to vascular access and administration of intravenous treatment, and shows how establishing and maintaining a route of access to the bloodstream is essential for patients in acute care today. Until now, little thought has been given to an intentional process to guide selection, insertion and management of vascular access devices (VADs) and by default actions are based on crisis management when a quickly selected VAD fails. The book details how VHP establishes a framework or pathway model for each step of the patient experience, intentionally guiding, improving and eliminating risk when possible. The evidence points to the fact that reducing fragmentation, establishing a pathway, and teaching the process to all stakeholders reduces complications with intravenous therapy, improves efficiency and diminishes cost. As such this book appeals to bedside nurses, physicians and other health professionals.
Author: Tom Wolfe Publisher: Little, Brown ISBN: 0316214582 Category : Fiction Languages : en Pages : 407
Book Description
A big, panoramic story of the new America, as told by our master chronicler of the way we live now. As a police launch speeds across Miami's Biscayne Bay -- with officer Nestor Camacho on board -- Tom Wolfe is off and running. Into the feverous landscape of the city, he introduces the Cuban mayor, the black police chief, a wanna-go-muckraking young journalist and his Yale-marinated editor; an Anglo sex-addiction psychiatrist and his Latina nurse by day, loin lock by night-until lately, the love of Nestor's life; a refined, and oh-so-light-skinned young woman from Haiti and her Creole-spouting, black-gang-banger-stylin' little brother; a billionaire porn addict, crack dealers in the 'hoods, "de-skilled" conceptual artists at the Miami Art Basel Fair, "spectators" at the annual Biscayne Bay regatta looking only for that night's orgy, yenta-heavy ex-New Yorkers at an "Active Adult" condo, and a nest of shady Russians. Based on the same sort of detailed, on-scene, high-energy reporting that powered Tom Wolfe's previous bestselling novels, Back to Blood is another brilliant, spot-on, scrupulous, and often hilarious reckoning with our times.
Author: Gert Fricker Publisher: Springer ISBN: 3662437872 Category : Science Languages : en Pages : 169
Book Description
Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.
Author: Tess Gerritsen
Author: Tess Gerritsen
Author: Roland N. Pittman
Author: Institute of Medicine
Author: 
Author: Carlos Franco-Paredes
Author: J. Gordon Betts
Author: Wm. Michael Dunne, Jr.
Author: Nancy L. Moureau
Author: Tom Wolfe
Author: Gert Fricker