The Birth of a Drug PDF Download

Author:
Publisher:
ISBN:
Category : Drugs
Languages : en
Pages :

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Author: Marek Kohn
Publisher: Granta Books
ISBN: 1847088864
Category : History
Languages : en
Pages : 212

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This is a discussion of the transformation of drug use (especially morphine and cocaine, which was once commonly available in any chemist's shop) into a national menace. It revolves around the death of Billie Carleton, a West End musical actress, in 1918. Its cast of characters includes Brilliant Chang, a Chinese restaurant proprietor and Edgar Manning, a jazz drummer from Jamaica. They were eventually identified as the villains of the affair and invested with a highly charged sexual menace. Around them, in the streets off Shaftesbury Avenue, there swirled a raffish group of seedy and entitled hedonists. Britain was horrified and fascinated, and so the drug problem was born amid a gush of exotic tabloid detail.

Author: The Open University
Publisher: The Open University
ISBN:
Category :
Languages : en
Pages : 27

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This 4-hour free course looked at the use of organic chemistry in new drug development, using the example of a new drug for high blood pressure.

Author: Jonathan Eig
Publisher: W. W. Norton & Company
ISBN: 0393245942
Category : Science
Languages : en
Pages : 255

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A Chicago Tribune "Best Books of 2014" • A Slate "Best Books 2014: Staff Picks" • A St. Louis Post-Dispatch "Best Books of 2014" The fascinating story of one of the most important scientific discoveries of the twentieth century. We know it simply as "the pill," yet its genesis was anything but simple. Jonathan Eig's masterful narrative revolves around four principal characters: the fiery feminist Margaret Sanger, who was a champion of birth control in her campaign for the rights of women but neglected her own children in pursuit of free love; the beautiful Katharine McCormick, who owed her fortune to her wealthy husband, the son of the founder of International Harvester and a schizophrenic; the visionary scientist Gregory Pincus, who was dismissed by Harvard in the 1930s as a result of his experimentation with in vitro fertilization but who, after he was approached by Sanger and McCormick, grew obsessed with the idea of inventing a drug that could stop ovulation; and the telegenic John Rock, a Catholic doctor from Boston who battled his own church to become an enormously effective advocate in the effort to win public approval for the drug that would be marketed by Searle as Enovid. Spanning the years from Sanger’s heady Greenwich Village days in the early twentieth century to trial tests in Puerto Rico in the 1950s to the cusp of the sexual revolution in the 1960s, this is a grand story of radical feminist politics, scientific ingenuity, establishment opposition, and, ultimately, a sea change in social attitudes. Brilliantly researched and briskly written, The Birth of the Pill is gripping social, cultural, and scientific history.

Author: William Rosen
Publisher: Penguin
ISBN: 0698184106
Category : Medical
Languages : en
Pages : 370

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The epic history of how antibiotics were born, saving millions of lives and creating a vast new industry known as Big Pharma. As late as the 1930s, virtually no drug intended for sickness did any good; doctors could set bones, deliver babies, and offer palliative care. That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955, the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections. William Rosen captures this revolution with all its false starts, lucky surprises, and eccentric characters. He explains why, given the complex nature of bacteria—and their ability to rapidly evolve into new forms—the only way to locate and test potential antibiotic strains is by large-scale, systematic, trial-and-error experimentation. Organizing that research needs large, well-funded organizations and businesses, and so our entire scientific-industrial complex, built around the pharmaceutical company, was born. Timely, engrossing, and eye-opening, Miracle Cure is a must-read science narrative—a drama of enormous range, combining science, technology, politics, and economics to illuminate the reasons behind one of the most dramatic changes in humanity’s relationship with nature since the invention of agriculture ten thousand years ago.

Author: Dan Russell
Publisher:
ISBN:
Category : History
Languages : en
Pages : 380

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"Shamanism and the Drug Propaganda" is a popularly written college-level introduction to ancient history and the Greek classics. The text is fully annotated and illuminated by 200 genuine pharmaco-shamanic images from the ancient world. Since it is popularly written, and very heavily illustrated with the remarkable, overtly pharmaco-shamanic art of the ancient world, it reads like a movie. But a movie with profound psychological and political relevance for the contemporary world, since it uses the words and pictures of our ancestors to address contemporary issues. In this sense, it compares to "The Chalice and the Blade" and "Food of the Gods," two recent bestsellers of similar intent. As such, the book is a unique tool for exciting undergraduates about the contemporary relevance of ancient history and the Greek classics. This was the intent of Jane Ellen Harrison in her "Prolegomena" and "Epilegomena to the Study of Greek Religion." Harrison was the most influential classicist of the twentieth century, and, not coincidentally, the most influential feminist historian of the century as well. A major feature of "Shamanism and the Drug Propaganda," in 4 of its 17 chapters, is its summary of Harrison's seminal thesis, in her own words. Harrison was concerned with the historical and psychological transition from the originary matriarchal conscious of tribal culture to the warrior-oriented patriarchal consciousness of industrial culture. She understood this transition to be central to the process of industrial enslavement. That enslavement necessarily demonized the power-rites, the rites de passage, as she called them, of tribal cultures. That is, Harrison pointed to the tribal, the matriarchal pre-industrial roots of Classical, patriarchal-industrial, Greek culture. She was, therefore, concerned with originary, tribal, Greek sacramentalism. Herbal magic, real pharmaco-shamanism, is at the core of all matriarchal cultures. The Goddess does not separate from her herbal magic, from her invention of medicine. The central sacrament of all Paleolithic, Neolithic and Bronze Age cultures known is an inebriative herb, a plant totem, which became metaphoric of the communal epiphany. These herbs, herbal concoctions and herbal metaphors are at the heart of all mythologies. They include such familiar images as the Burning Bush, the Tree of Life, the Cross, the Golden Bough, the Forbidden Fruit, the Blood of Christ, the Blood of Dionysos, the Holy Grail (or rather its contents), the Chalice (Kalyx: 'flower cup'), the Golden Flower (Chrysanthemon), Ambrosia (Ambrotos: 'immortal'), Nectar (Nektar: 'overcomes death'), the Sacred Lotus, the Golden Apples, the Mystic Mandrake, the Mystic Rose, the Divine Mushroom (teonanacatl), the Divine Water Lily, Soma, Ayahuasca ('Vine of the Soul'), Kava, Iboga, Mama Coca and Peyote Woman. They are the archetypal - the emotionally, the instantaneously understood - symbols at the center of the drug propaganda. A sexually attractive man or woman is an archetypal image, the basis of most advertising. A loaf of bread is an archetypal image. The emotional impact of the sacramental herbal images, or, rather, the historical confusion of their natural function, is central to the successful manipulation of mass emotion and individual self-image. That is, contemporary politics has an unconscious, an evolutionary element, that involves the industrial manipulation of instinct. That manipulation can only be understood by contemplating what elements of our evolutionary inheritance contemporary inquisitors want forgotten.

Author: Vitthal S. Kulkarni
Publisher: Elsevier
ISBN: 0815520263
Category : Science
Languages : en
Pages : 328

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With the improvements in formulation science and certain transdermal delivery technologies, the non-invasive mode of drug delivery is now ready to compete with traditional methods of oral and injectible routes of drug delivery. The Handbook of Non-Invasive Drug Delivery Systems encompasses the broad field of non-invasive drug delivery systems that include drug delivery via topical, transdermal-passive, transdermal-active (device- aided enhanced penetration), trans-mucosal membrane, trans-ocular membrane as well as delivery via alveolar membrane from inhaled medication. Patient compliance has been found to be much higher when administrated by non-invasive routes and therefore they are considered to be a preferred mode of drug delivery. The book includes both science and technological aspects of new drug delivery systems. Its unique focus is that it is on new drug delivery systems that are considered to be "non-invasive". Other unique features include a chapter on Regulatory Aspects of non-invasive systems and one on FDA guidance for topical nano-drug delivery. Two chapters covering market trends and perspectives, as well as providing guidance to those marketing such systems are also included.

Author: Lisa Vozza
Publisher: World Scientific
ISBN: 1786343002
Category : Medical
Languages : en
Pages : 186

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This book is an excursion into the drug development process, from the initial conception in a chemical or molecular biology lab, via tests in isolated cells and animals, to the stage of clinical trials. The human body is a complex ecosystem where little is conclusively known in terms of its response to medication, for both sick and healthy individuals. The considerable degree of uncertainty inherent in health-related research can lead to approval of controversial medicines, particularly in high-stakes scenarios and medical crises. Real-life examples are drawn on here to explain the decision making processes behind the acceptance of new drugs, disproving misconceptions around medicines by delving into the history and current practice of the drug development process.Originally written in Italian, How Medicines are Born helps patients, students, public health officials physicians, healthcare practitioners and biomedical scientists make informed decisions on the benefits and disadvantages of select medicine based on an understanding of the history of drug development.Published in Italian (2014), M D'Incalci & L Vozza, Come Nascono le Medicine; La scienza imperfetta dei farmaci. Bologna: ZanichelliRelated Link(s)

Author: Andrew Monteith
Publisher: NYU Press
ISBN: 1479817910
Category : Law
Languages : en
Pages : 304

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Recovers the religious origins of the War on Drugs Many people view the War on Drugs as a contemporary phenomenon invented by the Nixon administration. But as this new book shows, the conflict actually began more than a century before, when American Protestants began the temperance movement and linked drug use with immorality. Christian Nationalism and the Birth of the War on Drugs argues that this early drug war was deeply rooted in Christian impulses. While many scholars understand Prohibition to have been a Protestant undertaking, it is considerably less common to consider the War on Drugs this way, in part because racism has understandably been the focal point of discussions of the drug war. Antidrug activists expressed—and still do express--blatant white supremacist and nativist motives. Yet this book argues that that racism was intertwined with religious impulses. Reformers pursued the “civilizing mission,” a wide-ranging project that sought to protect “child races” from harmful influences while remodeling their cultures to look like Europe and the United States. Most reformers saw Christianity as essential to civilization and missionaries felt that banning drugs would encourage religious conversion and progress. This compelling work of scholarship radically reshapes our understanding of one of the longest and most damaging conflicts in modern American history, making the case that we cannot understand the War on Drugs unless we understand its religious origins.

Author: Gerald G. Briggs
Publisher: Lippincott Williams & Wilkins
ISBN: 1451153597
Category : Medical
Languages : en
Pages : 1728

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An A-Z listing of drugs by generic name. Each monograph summarizes the known and/or possible effects of the drug on the fetus. It also summarizes the known/possible passage of the drug into the human breast milk. A careful and exhaustive summarization of the world literature as it relates to drugs in pregnancy and lacation. Each monograph contains six parts: generic US name, Pharmacologic class, Risk factor, Fetal risk summary, Breast feeding summary, References