Author: Jennie G. Noll
Publisher: Springer
ISBN: 3319725890
Category : Psychology
Languages : en
Pages : 178
Book Description
This innovative collection extends the emerging field of stress biology to examine the effects of a substantial source of early-life stress: child abuse and neglect. Research findings across endocrinology, immunology, neuroscience, and genomics supply new insights into the psychological variables associated with adversity in children and its outcomes. These compelling interdisciplinary data add to a promising model of biological mechanisms involved in individual resilience amid chronic maltreatment and other trauma. At the same time, these results also open out distinctive new possibilities for serving vulnerable children and youth, focusing on preventing, intervening in, and potentially even reversing the effects of chronic early trauma. Included in the coverage: Biological embedding of child maltreatment Toward an adaptation-based approach to resilience Developmental traumatology: brain development and maltreated children with and without PTSD Childhood maltreatment and pediatric PTSD: abnormalities in threat neural circuitry An integrative temporal framework for psychological resilience The Biology of Early Life Stress is important reading for child maltreatment researchers; clinical psychologists; educators in counseling, psychology, trauma, and nursing; physicians; and state- and federal-level policymakers. Advocates, child and youth practitioners, and clinicians in general will find it a compelling resource.
The Biology of Early Life Stress
Author: Jennie G. Noll
Publisher: Springer
ISBN: 3319725890
Category : Psychology
Languages : en
Pages : 178
Book Description
This innovative collection extends the emerging field of stress biology to examine the effects of a substantial source of early-life stress: child abuse and neglect. Research findings across endocrinology, immunology, neuroscience, and genomics supply new insights into the psychological variables associated with adversity in children and its outcomes. These compelling interdisciplinary data add to a promising model of biological mechanisms involved in individual resilience amid chronic maltreatment and other trauma. At the same time, these results also open out distinctive new possibilities for serving vulnerable children and youth, focusing on preventing, intervening in, and potentially even reversing the effects of chronic early trauma. Included in the coverage: Biological embedding of child maltreatment Toward an adaptation-based approach to resilience Developmental traumatology: brain development and maltreated children with and without PTSD Childhood maltreatment and pediatric PTSD: abnormalities in threat neural circuitry An integrative temporal framework for psychological resilience The Biology of Early Life Stress is important reading for child maltreatment researchers; clinical psychologists; educators in counseling, psychology, trauma, and nursing; physicians; and state- and federal-level policymakers. Advocates, child and youth practitioners, and clinicians in general will find it a compelling resource.
Publisher: Springer
ISBN: 3319725890
Category : Psychology
Languages : en
Pages : 178
Book Description
This innovative collection extends the emerging field of stress biology to examine the effects of a substantial source of early-life stress: child abuse and neglect. Research findings across endocrinology, immunology, neuroscience, and genomics supply new insights into the psychological variables associated with adversity in children and its outcomes. These compelling interdisciplinary data add to a promising model of biological mechanisms involved in individual resilience amid chronic maltreatment and other trauma. At the same time, these results also open out distinctive new possibilities for serving vulnerable children and youth, focusing on preventing, intervening in, and potentially even reversing the effects of chronic early trauma. Included in the coverage: Biological embedding of child maltreatment Toward an adaptation-based approach to resilience Developmental traumatology: brain development and maltreated children with and without PTSD Childhood maltreatment and pediatric PTSD: abnormalities in threat neural circuitry An integrative temporal framework for psychological resilience The Biology of Early Life Stress is important reading for child maltreatment researchers; clinical psychologists; educators in counseling, psychology, trauma, and nursing; physicians; and state- and federal-level policymakers. Advocates, child and youth practitioners, and clinicians in general will find it a compelling resource.
Childhood Disrupted
Author: Donna Jackson Nakazawa
Publisher: Simon and Schuster
ISBN: 1476748365
Category : Family & Relationships
Languages : en
Pages : 304
Book Description
An examination of the link between Adverse Childhood Events (ACE's) and adult illnesses.
Publisher: Simon and Schuster
ISBN: 1476748365
Category : Family & Relationships
Languages : en
Pages : 304
Book Description
An examination of the link between Adverse Childhood Events (ACE's) and adult illnesses.
The Impact of Early Life Trauma on Health and Disease
Author: Ruth A. Lanius
Publisher: Cambridge University Press
ISBN: 9780521880268
Category : Medical
Languages : en
Pages : 329
Book Description
There is now ample evidence from the preclinical and clinical fields that early life trauma has both dramatic and long-lasting effects on neurobiological systems and functions that are involved in different forms of psychopathology as well as on health in general. To date, a comprehensive review of the recent research on the effects of early and later life trauma is lacking. This book fills an obvious gap in academic and clinical literature by providing reviews which summarize and synthesize these findings. Topics considered and discussed include the possible biological and neuropsychological effects of trauma at different epochs and their effect on health. This book will be essential reading for psychiatrists, clinical psychologists, mental health professionals, social workers, pediatricians and specialists in child development.
Publisher: Cambridge University Press
ISBN: 9780521880268
Category : Medical
Languages : en
Pages : 329
Book Description
There is now ample evidence from the preclinical and clinical fields that early life trauma has both dramatic and long-lasting effects on neurobiological systems and functions that are involved in different forms of psychopathology as well as on health in general. To date, a comprehensive review of the recent research on the effects of early and later life trauma is lacking. This book fills an obvious gap in academic and clinical literature by providing reviews which summarize and synthesize these findings. Topics considered and discussed include the possible biological and neuropsychological effects of trauma at different epochs and their effect on health. This book will be essential reading for psychiatrists, clinical psychologists, mental health professionals, social workers, pediatricians and specialists in child development.
Stress and Health
Author: William R. Lovallo
Publisher: SAGE Publications
ISBN: 1483378284
Category : Psychology
Languages : en
Pages : 366
Book Description
Stress and Health: Biological and Psychological Interactions is a brief and accessible examination of psychological stress and its psychophysiological relationships with cognition, emotions, brain functions, and the peripheral mechanisms by which the body is regulated. Updated throughout, the Third Edition covers two new and significant areas of emerging research: how our early life experiences alter key stress responsive systems at the level of gene expression; and what large, normal, and small stress responses may mean for our overall health and well-being.
Publisher: SAGE Publications
ISBN: 1483378284
Category : Psychology
Languages : en
Pages : 366
Book Description
Stress and Health: Biological and Psychological Interactions is a brief and accessible examination of psychological stress and its psychophysiological relationships with cognition, emotions, brain functions, and the peripheral mechanisms by which the body is regulated. Updated throughout, the Third Edition covers two new and significant areas of emerging research: how our early life experiences alter key stress responsive systems at the level of gene expression; and what large, normal, and small stress responses may mean for our overall health and well-being.
Neurobiology of Bipolar Disorder
Author: Joao L. de Quevedo
Publisher: Academic Press
ISBN: 012819183X
Category : Medical
Languages : en
Pages : 472
Book Description
The Neurobiology of Bipolar Disorder: Road to Novel Therapeutics combines the basic neurobiology of bipolar disorder with discussions of the most recent advances in research, including the interacting pathways implicated in the pathophysiology of bipolar disorder, genetic approaches and the pharmacogenomics of bipolar disorder. The basic foundational understanding of the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research combine to aid advanced students and researchers in their understanding of bipolar disorder management using novel and fast-acting pharmaceutical and neuromodulatory approaches. - Aids readers in understanding bipolar disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations - Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments to novel therapeutics - Synthesizes a discussion of the cellular and molecular mechanisms underlying symptoms with clinical aspects of bipolar disorder
Publisher: Academic Press
ISBN: 012819183X
Category : Medical
Languages : en
Pages : 472
Book Description
The Neurobiology of Bipolar Disorder: Road to Novel Therapeutics combines the basic neurobiology of bipolar disorder with discussions of the most recent advances in research, including the interacting pathways implicated in the pathophysiology of bipolar disorder, genetic approaches and the pharmacogenomics of bipolar disorder. The basic foundational understanding of the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research combine to aid advanced students and researchers in their understanding of bipolar disorder management using novel and fast-acting pharmaceutical and neuromodulatory approaches. - Aids readers in understanding bipolar disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations - Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments to novel therapeutics - Synthesizes a discussion of the cellular and molecular mechanisms underlying symptoms with clinical aspects of bipolar disorder
Programming HPA-axis by early life experience: Mechanisms of stress susceptibility and adaptation
Author: Rachel Yehuda
Publisher: Frontiers Media SA
ISBN: 2889194817
Category : Diseases of the endocrine glands. Clinical endocrinology
Languages : en
Pages : 141
Book Description
Experiences during early life program the central nervous- and endocrine-systems with consequences for susceptibility to physical and mental disorders. These programming effects depend on genetic and epigenetic factors, and their outcome leads to an adaptive or maladaptive phenotype to a given later environmental context. This Research Topic focused on the hypothalamus-pituitary-adrenal (HPA)-axis and stress-related phenotypes, and on how HPA-axis programming by the environment precisely occurs. We included original research, mini-review and review papers on a broad range of topics related to HPA-axis programming.
Publisher: Frontiers Media SA
ISBN: 2889194817
Category : Diseases of the endocrine glands. Clinical endocrinology
Languages : en
Pages : 141
Book Description
Experiences during early life program the central nervous- and endocrine-systems with consequences for susceptibility to physical and mental disorders. These programming effects depend on genetic and epigenetic factors, and their outcome leads to an adaptive or maladaptive phenotype to a given later environmental context. This Research Topic focused on the hypothalamus-pituitary-adrenal (HPA)-axis and stress-related phenotypes, and on how HPA-axis programming by the environment precisely occurs. We included original research, mini-review and review papers on a broad range of topics related to HPA-axis programming.
The Promise of Adolescence
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309490111
Category : Social Science
Languages : en
Pages : 493
Book Description
Adolescenceâ€"beginning with the onset of puberty and ending in the mid-20sâ€"is a critical period of development during which key areas of the brain mature and develop. These changes in brain structure, function, and connectivity mark adolescence as a period of opportunity to discover new vistas, to form relationships with peers and adults, and to explore one's developing identity. It is also a period of resilience that can ameliorate childhood setbacks and set the stage for a thriving trajectory over the life course. Because adolescents comprise nearly one-fourth of the entire U.S. population, the nation needs policies and practices that will better leverage these developmental opportunities to harness the promise of adolescenceâ€"rather than focusing myopically on containing its risks. This report examines the neurobiological and socio-behavioral science of adolescent development and outlines how this knowledge can be applied, both to promote adolescent well-being, resilience, and development, and to rectify structural barriers and inequalities in opportunity, enabling all adolescents to flourish.
Publisher: National Academies Press
ISBN: 0309490111
Category : Social Science
Languages : en
Pages : 493
Book Description
Adolescenceâ€"beginning with the onset of puberty and ending in the mid-20sâ€"is a critical period of development during which key areas of the brain mature and develop. These changes in brain structure, function, and connectivity mark adolescence as a period of opportunity to discover new vistas, to form relationships with peers and adults, and to explore one's developing identity. It is also a period of resilience that can ameliorate childhood setbacks and set the stage for a thriving trajectory over the life course. Because adolescents comprise nearly one-fourth of the entire U.S. population, the nation needs policies and practices that will better leverage these developmental opportunities to harness the promise of adolescenceâ€"rather than focusing myopically on containing its risks. This report examines the neurobiological and socio-behavioral science of adolescent development and outlines how this knowledge can be applied, both to promote adolescent well-being, resilience, and development, and to rectify structural barriers and inequalities in opportunity, enabling all adolescents to flourish.
Born Anxious
Author: Daniel P. Keating
Publisher: Macmillan + ORM
ISBN: 146688648X
Category : Psychology
Languages : en
Pages : 225
Book Description
Why are we the way we are? Why do some of us find it impossible to calm a quick temper or to shake anxiety? The debate has always been divided between nature and nurture, but as psychology professor Daniel P. Keating demonstrates in Born Anxious, new DNA science points to a third factor that allows us to inherit both the nature and the nurture of previous generations—with significant consequences. Born Anxious introduces a new word into our lexicon: “methylated.” It’s short for “epigenetic methylation,” and it offers insight into behaviors we have all observed but never understood—the boss who goes ballistic at the slightest error; the infant who can’t be calmed; the husband who can’t fall asleep at night. In each case, because of an exposure to environmental adversity in utero or during the first year of life, a key stress system has been welded into the “on” position by the methylation process, predisposing the child’s body to excessive levels of the stress hormone cortisol. The effect: lifelong, unrelenting stress and its consequences–from school failure to nerve-wracking relationships to early death. Early adversity happens in all levels of society but as income gaps widen, social inequality and fear of the future have become the new predators; in Born Anxious, Daniel P. Keating demonstrates how we can finally break the cycle.
Publisher: Macmillan + ORM
ISBN: 146688648X
Category : Psychology
Languages : en
Pages : 225
Book Description
Why are we the way we are? Why do some of us find it impossible to calm a quick temper or to shake anxiety? The debate has always been divided between nature and nurture, but as psychology professor Daniel P. Keating demonstrates in Born Anxious, new DNA science points to a third factor that allows us to inherit both the nature and the nurture of previous generations—with significant consequences. Born Anxious introduces a new word into our lexicon: “methylated.” It’s short for “epigenetic methylation,” and it offers insight into behaviors we have all observed but never understood—the boss who goes ballistic at the slightest error; the infant who can’t be calmed; the husband who can’t fall asleep at night. In each case, because of an exposure to environmental adversity in utero or during the first year of life, a key stress system has been welded into the “on” position by the methylation process, predisposing the child’s body to excessive levels of the stress hormone cortisol. The effect: lifelong, unrelenting stress and its consequences–from school failure to nerve-wracking relationships to early death. Early adversity happens in all levels of society but as income gaps widen, social inequality and fear of the future have become the new predators; in Born Anxious, Daniel P. Keating demonstrates how we can finally break the cycle.
Systems Neuroscience in Depression
Author: Thomas Frodl
Publisher: Academic Press
ISBN: 0128026286
Category : Psychology
Languages : en
Pages : 422
Book Description
Systems Neuroscience in Depression provides a comprehensive overview of the normal and depressed brain processes as studied from a systems neuroscience perspective. Systems neuroscience uses a wide variety of approaches to study how networks of neurons form the bases of higher brain function. A broad overview is discussed starting with a background from neurodevelopment and neural understanding as well as novel treatment approaches for depression. This book covers basic developmental aspects and depressive psychopathology, as well as the basic scientific background from animal models and experimental research. Current advances in systems neuroscience are highlighted in studies from child and adolescent psychiatry. Integrated approaches are presented with regards to genetics, neuroimaging and neuroinflammation as well as neuroendocrinology. The field of systems and network neuroscience is evolving rapidly and this book provides a greatly needed resource for researchers and practitioners in systems neuroscience and psychiatry. - Knowledge covering the whole life span from early to later life - Comprehensively written chapters developing from molecules via epigenetics and neural circuits to clinical neuroscience - Understanding the neurobiology of major depressive disorder - Integrating stress and environmental factors with molecular underpinnings - More than 25 illustrations and tables
Publisher: Academic Press
ISBN: 0128026286
Category : Psychology
Languages : en
Pages : 422
Book Description
Systems Neuroscience in Depression provides a comprehensive overview of the normal and depressed brain processes as studied from a systems neuroscience perspective. Systems neuroscience uses a wide variety of approaches to study how networks of neurons form the bases of higher brain function. A broad overview is discussed starting with a background from neurodevelopment and neural understanding as well as novel treatment approaches for depression. This book covers basic developmental aspects and depressive psychopathology, as well as the basic scientific background from animal models and experimental research. Current advances in systems neuroscience are highlighted in studies from child and adolescent psychiatry. Integrated approaches are presented with regards to genetics, neuroimaging and neuroinflammation as well as neuroendocrinology. The field of systems and network neuroscience is evolving rapidly and this book provides a greatly needed resource for researchers and practitioners in systems neuroscience and psychiatry. - Knowledge covering the whole life span from early to later life - Comprehensively written chapters developing from molecules via epigenetics and neural circuits to clinical neuroscience - Understanding the neurobiology of major depressive disorder - Integrating stress and environmental factors with molecular underpinnings - More than 25 illustrations and tables
Fundamentals of Brain Network Analysis
Author: Alex Fornito
Publisher: Academic Press
ISBN: 0124081185
Category : Medical
Languages : en
Pages : 496
Book Description
Fundamentals of Brain Network Analysis is a comprehensive and accessible introduction to methods for unraveling the extraordinary complexity of neuronal connectivity. From the perspective of graph theory and network science, this book introduces, motivates and explains techniques for modeling brain networks as graphs of nodes connected by edges, and covers a diverse array of measures for quantifying their topological and spatial organization. It builds intuition for key concepts and methods by illustrating how they can be practically applied in diverse areas of neuroscience, ranging from the analysis of synaptic networks in the nematode worm to the characterization of large-scale human brain networks constructed with magnetic resonance imaging. This text is ideally suited to neuroscientists wanting to develop expertise in the rapidly developing field of neural connectomics, and to physical and computational scientists wanting to understand how these quantitative methods can be used to understand brain organization. - Winner of the 2017 PROSE Award in Biomedicine & Neuroscience and the 2017 British Medical Association (BMA) Award in Neurology - Extensively illustrated throughout by graphical representations of key mathematical concepts and their practical applications to analyses of nervous systems - Comprehensively covers graph theoretical analyses of structural and functional brain networks, from microscopic to macroscopic scales, using examples based on a wide variety of experimental methods in neuroscience - Designed to inform and empower scientists at all levels of experience, and from any specialist background, wanting to use modern methods of network science to understand the organization of the brain
Publisher: Academic Press
ISBN: 0124081185
Category : Medical
Languages : en
Pages : 496
Book Description
Fundamentals of Brain Network Analysis is a comprehensive and accessible introduction to methods for unraveling the extraordinary complexity of neuronal connectivity. From the perspective of graph theory and network science, this book introduces, motivates and explains techniques for modeling brain networks as graphs of nodes connected by edges, and covers a diverse array of measures for quantifying their topological and spatial organization. It builds intuition for key concepts and methods by illustrating how they can be practically applied in diverse areas of neuroscience, ranging from the analysis of synaptic networks in the nematode worm to the characterization of large-scale human brain networks constructed with magnetic resonance imaging. This text is ideally suited to neuroscientists wanting to develop expertise in the rapidly developing field of neural connectomics, and to physical and computational scientists wanting to understand how these quantitative methods can be used to understand brain organization. - Winner of the 2017 PROSE Award in Biomedicine & Neuroscience and the 2017 British Medical Association (BMA) Award in Neurology - Extensively illustrated throughout by graphical representations of key mathematical concepts and their practical applications to analyses of nervous systems - Comprehensively covers graph theoretical analyses of structural and functional brain networks, from microscopic to macroscopic scales, using examples based on a wide variety of experimental methods in neuroscience - Designed to inform and empower scientists at all levels of experience, and from any specialist background, wanting to use modern methods of network science to understand the organization of the brain