Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download A Pharmacology Primer PDF full book. Access full book title A Pharmacology Primer by Terry P. Kenakin. Download full books in PDF and EPUB format.
Author: Terry P. Kenakin Publisher: Academic Press ISBN: 0323992900 Category : Medical Languages : en Pages : 504
Book Description
A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Sixth Edition features the latest research surrounding the application of pharmacology in drug discovery in an effort to equip readers with a deeper understanding of complex and rapid changes in this field. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for anyone involved in drug discovery. This edition has been reorganized for better flow and clarity and includes material on new technologies for screening (virtual, DNA encoded libraires, fragment-based) and a major section on phenotypic (target agnostic) screening for new leads and determination of drug targets. With full color illustrations as well as new examples throughout, this book remains a top reference for all industry and academic scientists and students directly involved in drug discovery or pharmacologic research. New material includes a discussion of the determination of target engagement, including numerous new ways to demonstrate the physical interaction of molecules with drug targets and new drug candidates such a mRNA, gene therapy, antibodies and information on CRISPR and genomics. - Highlights changes surrounding the strategy of drug discovery, providing a comprehensive reference with advances in the methods involved in lead optimization and more effective drug discovery - Includes multiple new sections on screening, phenotypic (target agnostic) screening for new leads, and determination of new drug targets - Illustrates the application of rapid, inexpensive assays to predict activity in the therapeutic setting, showing data outcomes and the limitations inherent in interpreting this data - Includes test questions and answers
Author: Lynn Coady Publisher: Vintage ISBN: 0307961362 Category : Fiction Languages : en Pages : 286
Book Description
A piercing epistolary novel, The Antagonist explores, with wit and compassion, how the impressions of others shape, pervert, and flummox both our perceptions of ourselves and our very nature. Gordon Rankin Jr., aka “Rank,” thinks of himself as “King Midas in reverse”—and indeed misfortune seems to follow him at every turn. Against his will and his nature, he has long been considered—given his enormous size and strength—a goon and enforcer by his classmates, by his hockey coaches, and, not least, by his “tiny, angry” father. He gamely lives up to their expectations, until a vicious twist of fate forces him to flee underground. Now pushing forty, he discovers that an old, trusted friend from his college days has published a novel that borrows freely from the traumatic events of Rank’s own life. Outraged by this betrayal and feeling cruelly misrepresented, he bashes out his own version of his story in a barrage of e-mails to the novelist that range from funny to furious to heartbreaking. With The Antagonist, Lynn Coady demonstrates all of the gifts that have made her one of Canada’s most respected young writers. Here she gives us an astonishing story of sons and fathers and mothers, of the rewards and betrayals of male friendship, and a large-spirited, hilarious, and exhilarating portrait of a man tearing his life apart in order to put himself back together. This ebook edition includes a Reading Group Guide.
Author: Dianne K. Salerni Publisher: Harper Collins ISBN: 0062272179 Category : Juvenile Fiction Languages : en Pages : 189
Book Description
Fans of Percy Jackson will devour this first book in Dianne K. Salerni's time-bending series that combines exciting magic and pulse-pounding suspense. In this riveting fantasy adventure, thirteen-year-old Jax Aubrey discovers a secret eighth day with roots tracing back to Arthurian legend. When Jax wakes up to a world without any people in it, he assumes it's the zombie apocalypse. But when he runs into his eighteen-year-old guardian, Riley Pendare, he learns that he's really in the eighth day—an extra day sandwiched between Wednesday and Thursday. Some people—like Jax and Riley—are Transitioners, able to live in all eight days, while others, including Evangeline, the elusive teenage girl who's been hiding in the house next door, exist only on this special day. And there's a reason Evangeline's hiding. She is a descendant of the powerful wizard Merlin, and there is a group of people who wish to use her in order to destroy the normal seven-day world and all who live in it. Torn between protecting his new friend and saving the entire human race from complete destruction, Jax is faced with an impossible choice. Even with an eighth day, time is running out. Stay tuned for The Inquisitor's Mark, the spellbinding second novel in the Eighth Day series!
Author: Bethany Clift Publisher: Hodder Paperbacks ISBN: 9781529332162 Category : Fiction Languages : en Pages : 0
Book Description
'A riotous, black-humoured tonic' Independent 'A masterpiece of modern fiction' Sophie Cousens December 2023. The human race has fought a deadly virus and lost. The only things left from the world before are burning cities and rotting corpses. But in London, one woman is still alive. Although she may be completely unprepared for her new existence, as someone who has spent her life trying to fit in, being alone is surprisingly liberating. Determined to discover if she really is the last survivor on earth, she sets off on an extraordinary adventure, with only an abandoned golden retriever named Lucky for company. Maybe she'll find a better life or maybe she'll die along the way. But whatever happens, the end of everything will be her new beginning. 'Fresh, frank, funny' Elizabeth Kay 'Brilliant. Creepy, witty, laugh-out-loud and shudder-inducing' Harriet Walker 'Harrowing, unflinching and uplifting' Jennifer Saint 'Original, brutal, funny and hugely addictive!' Emma Cooper
Author: K. M. Weiland Publisher: Penforasword Publishing, LLC ISBN: 9780985780494 Category : Languages : en Pages : 192
Book Description
This bestselling guide will help you choose the right type of outline to unleash your creativity as a writer, guide you in brainstorming plot ideas, and aid you in discovering your characters.
Author: Terry P. Kenakin Publisher: Academic Press ISBN: 0323992900 Category : Medical Languages : en Pages : 504
Book Description
A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Sixth Edition features the latest research surrounding the application of pharmacology in drug discovery in an effort to equip readers with a deeper understanding of complex and rapid changes in this field. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for anyone involved in drug discovery. This edition has been reorganized for better flow and clarity and includes material on new technologies for screening (virtual, DNA encoded libraires, fragment-based) and a major section on phenotypic (target agnostic) screening for new leads and determination of drug targets. With full color illustrations as well as new examples throughout, this book remains a top reference for all industry and academic scientists and students directly involved in drug discovery or pharmacologic research. New material includes a discussion of the determination of target engagement, including numerous new ways to demonstrate the physical interaction of molecules with drug targets and new drug candidates such a mRNA, gene therapy, antibodies and information on CRISPR and genomics. - Highlights changes surrounding the strategy of drug discovery, providing a comprehensive reference with advances in the methods involved in lead optimization and more effective drug discovery - Includes multiple new sections on screening, phenotypic (target agnostic) screening for new leads, and determination of new drug targets - Illustrates the application of rapid, inexpensive assays to predict activity in the therapeutic setting, showing data outcomes and the limitations inherent in interpreting this data - Includes test questions and answers
Author: Publisher: Soffer Publishing ISBN: 4149818665 Category : Languages : en Pages : 65
Author: Laura Robb Publisher: Corwin Press ISBN: 1506374298 Category : Education Languages : en Pages : 273
Book Description
Yes—we can have our cake and eat it too! We can improve students’ reading and writing performance without sacrificing authenticity. In Read, Talk, Write, Laura Robb shows us how. First, she makes sure students know the basics of six types of talk. Next, she shares 35 lessons that support rich conversation. Finally, she includes new pieces by Seymour Simon, Kathleen Krull, and others so you have texts to use right away. Read, Talk, Write: it’s a process your students not only can do, but one they will love to do.
Author: Louis E. Catron Publisher: Waveland Press ISBN: 1478608250 Category : Performing Arts Languages : en Pages : 379
Book Description
The Directors Vision is a dynamic, practical text that focuses equally on the art of interpretation and on problem-solving. Catron helps students develop an organized, step-by-step methodology from play analysis through performance. Practical focus: Catron deftly combines abstract ideas about directing with concrete strategies on preparing for production, auditions, casting, and rehearsals. Comprehensive scope: Included are important topics such as in-depth play analysis, directorial responsibilities and ethics, leadership techniques, how to work with actors, and problem-solving. Exercises: End-of-chapter exercises help students digest what theyve read and get actively involved in the craft of directing. Quotes and illustrations: Thoughts from well-known directors, actors, and writers appear throughout the book, providing motivation, insight, and perspective. Abundant photographs and diagrams offer effective, dynamic examples of concepts.
Author: Terry P. Kenakin
Author: Lynn Coady
Author: Kenneth C. Haugk
Author: Joyce Carol Oates
Author: Dianne K. Salerni
Author: Bethany Clift
Author: K. M. Weiland
Author: Terry P. Kenakin
Author: 
Author: Laura Robb
Author: Louis E. Catron