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Testosterone Replacement Per Guidelines

Testosterone Replacement Per Guidelines PDF Author: Durant Karen J.
Publisher:
ISBN:
Category : Evidence-based medicine
Languages : en
Pages : 0

Book Description
Low testosterone (LT) levels affect approximately four million men in the United States, but only about 5% received treatment. Testosterone is the most important male sex hormone. It helps the body produce and maintain adult male features. Testosterone deficiency syndrome can cause significant morbidity and substantial reduction in quality of life. Testosterone therapy can be safe if appropriate evaluation is done prior to treatment and during therapy. Basin et al. and Darby and Anawalt emphasized that there is a need for a standardized plan for men receiving testosterone replacement therarpy. Drug manufacturers are bringing this issue to the public's attention through direct-to-consumer advertisement. Due to aggressive marketing to the public, it is urgent that an evidence-based protocol be implemented as an increasing number of men will be inquiring about testosterone replacement. The project addressed the question: Do adult males with testosterone deficiency syndrome received appropriate evaluation pre and post initiation of testosterone replacement therapy? To answer the question, and evidence-based standardized testosterone replacement protocol derived from the Endocrine Society's Guidelines for Testosterone Therapy in Adult Man with Androgen Deficiency Syndromes was implemented in an independent famil practice clinic. In the clinic, the number of men inquiring about testosterone deficiency and replacement has increased in the past few years. The evidence-based practice framework that was used to guide this project was derived from the Larrabee's Evidence-Based Practice Change Model. The Theory of Unpleasant Symptoms was selected to provide the theoretical guide for the project. Primary care providers implemented testosterone replacement per the Endocrine Society's Guidelines for Testosterone Therapy in Adult Men with Androgen Deficiency Syndromes. Practice change outcomes were evaluated through chart audit before and after implementation of the guidelines. Over a three month period of time a total of 22 charts were reviewed. Baseline evaluation found the majority of patients were having their initial testosterone check by providers per guidelines but few providers were ordering the confirmatory testosterone level as recommended in the guidelines. Few patients were receiving the recommended lab evaluation prior to starting replacement therapy/. Approximately one third of all patients over 40 had a pre or post therapy digital rectal exam. The majority had post initiation of therapy lab but the prostate specific antigen (PSA) was often not completed. Patient care providers and medical assistants willingly implemented the Endocrine Society Guidelines for Testosterone Therapy in Adult Men with Androgen Deficiency Syndromes. This was evident in the post evaluation as improved outcomes were identified.

Testosterone Replacement Per Guidelines

Testosterone Replacement Per Guidelines PDF Author: Durant Karen J.
Publisher:
ISBN:
Category : Evidence-based medicine
Languages : en
Pages : 0

Book Description
Low testosterone (LT) levels affect approximately four million men in the United States, but only about 5% received treatment. Testosterone is the most important male sex hormone. It helps the body produce and maintain adult male features. Testosterone deficiency syndrome can cause significant morbidity and substantial reduction in quality of life. Testosterone therapy can be safe if appropriate evaluation is done prior to treatment and during therapy. Basin et al. and Darby and Anawalt emphasized that there is a need for a standardized plan for men receiving testosterone replacement therarpy. Drug manufacturers are bringing this issue to the public's attention through direct-to-consumer advertisement. Due to aggressive marketing to the public, it is urgent that an evidence-based protocol be implemented as an increasing number of men will be inquiring about testosterone replacement. The project addressed the question: Do adult males with testosterone deficiency syndrome received appropriate evaluation pre and post initiation of testosterone replacement therapy? To answer the question, and evidence-based standardized testosterone replacement protocol derived from the Endocrine Society's Guidelines for Testosterone Therapy in Adult Man with Androgen Deficiency Syndromes was implemented in an independent famil practice clinic. In the clinic, the number of men inquiring about testosterone deficiency and replacement has increased in the past few years. The evidence-based practice framework that was used to guide this project was derived from the Larrabee's Evidence-Based Practice Change Model. The Theory of Unpleasant Symptoms was selected to provide the theoretical guide for the project. Primary care providers implemented testosterone replacement per the Endocrine Society's Guidelines for Testosterone Therapy in Adult Men with Androgen Deficiency Syndromes. Practice change outcomes were evaluated through chart audit before and after implementation of the guidelines. Over a three month period of time a total of 22 charts were reviewed. Baseline evaluation found the majority of patients were having their initial testosterone check by providers per guidelines but few providers were ordering the confirmatory testosterone level as recommended in the guidelines. Few patients were receiving the recommended lab evaluation prior to starting replacement therapy/. Approximately one third of all patients over 40 had a pre or post therapy digital rectal exam. The majority had post initiation of therapy lab but the prostate specific antigen (PSA) was often not completed. Patient care providers and medical assistants willingly implemented the Endocrine Society Guidelines for Testosterone Therapy in Adult Men with Androgen Deficiency Syndromes. This was evident in the post evaluation as improved outcomes were identified.

Testosterone and Aging

Testosterone and Aging PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309090636
Category : Medical
Languages : en
Pages : 239

Book Description
Popular culture often equates testosterone with virility, strength, and the macho male physique. Viewed by some as an "antiaging tonic," testosterone's reputation and increased use by men of all ages in the United States have outpaced the scientific evidence about its potential benefits and risks. In particular there has been growing concern about an increase in the number of middle-aged and older men using testosterone and the lack of scientific data on the effect it may have on aging males. Studies of testosterone replacement therapy in older men have generally been of short duration, involving small numbers of participants and often lacking adequate controls. Testosterone and Aging weighs the options of future research directions, examines the risks and benefits of testosterone replacement therapy, assesses the potential public health impact of such therapy in the United States, and considers ethical issues related to the conduct of clinical trials. Testosterone therapy remains an attractive option to many men even as speculation abounds regarding its potential.

Advances in the Management of Testosterone Deficiency

Advances in the Management of Testosterone Deficiency PDF Author: T. Hugh Jones
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805586221
Category : Medical
Languages : en
Pages : 221

Book Description
Testosterone has an important influence on major organ systems and tissues, including brain, metabolism, cardiovascular as well as musculoskeletal and immune systems. Covering many clinical areas, this book pays particular attention to the diagnosis and management of hypogonadism, discussing current guidelines, biochemical assessment, new options in testosterone replacement therapy and long-term monitoring of treated men. Furthermore the role of testosterone deficiency in aging, obesity, muscle function and frailty and erectile dysfunction is covered. Recent evidence for the role of testosterone in the pathogenesis of chronic diseases such as diabetes, cardiovascular disease and osteoporosis is reported. New developments in the potential treatment of these clinical conditions are also. presented.Primarily of interest to endocrinologists, urologists, andrologists and sexologists, the range of topics covered is also relevant to primary care physicians, gerontologists, diabetologists and cardiologists.

Androgen Deficiency and Testosterone Replacement

Androgen Deficiency and Testosterone Replacement PDF Author: Wayne J.G. Hellstrom
Publisher: Humana Press
ISBN: 9781627038904
Category : Medical
Languages : en
Pages : 0

Book Description
Androgen Deficiency and Testosterone Replacement: Current Controversies and Strategies explores the difficulties around the diagnosis and treatment of androgen deficiency. The text examines the available evidence concerning the diagnosis and treatment of men with low testosterone. It also examines controversies in the identification and management of these men. While the information contained within will be of use to those who specialize in androgen deficiency and sexual medicine, the scope of the book will serve as a source of basic information about testosterone replacement and as a source of reasoned analysis of the controversies surrounding testosterone replacement in the aging male. Physicians and physician extenders will be able to apply evidence management principles to the evaluation and treatment of men with testosterone deficiency; supported by the most recent practice guidelines available. The authors represent a select group of physicians with expertise in androgen deficiency and replacement. Androgen Deficiency and Testosterone Replacement: Current Controversies and Strategies will be of great value to all physicians and physician extenders who deliver health care to men of all ages.

Testosterone

Testosterone PDF Author: Susan Nieschlag
Publisher: Springer Science & Business Media
ISBN: 3662008149
Category : Medical
Languages : en
Pages : 296

Book Description
New developments in testosterone therapy are summarized here by internationally renowned experts. They review both basic and clinical knowledge in fourteen chapters. The book begins with the biochemistry of testosterone, its biosynthesis, metabolism and mechanisms of action in target organs. Three chapters deal with specific aspects of testosterone action, namely its role in spermatogenesis, its psychotropic effects and its effects on bones. Syndromes caused by androgen resistance are described in order to highlight the importance of properly functioning enzymes and receptors in the target organs. Causes and symptoms of male hypogonadism, the major indication for testosterone treatment, are described. Five chapters are devoted to the pharmacology, pharmacokinetics and clinical uses and abuses of testosterone preparations. The new transdermal testosterone application is described in detail. Side effects of testosterone treatment are reviewed. The possible role of androgens in the development of prostatic hypertrophy and carcinoma is discussed extensively since this question is of major concern to the clinician.

Testosterone Deficiency in Men

Testosterone Deficiency in Men PDF Author: Hugh Jones
Publisher: Oxford University Press, USA
ISBN: 0199545138
Category : Medical
Languages : en
Pages : 179

Book Description
This book provides a background of essential knowledge on testosterone deficiency in men, including diagnosis and treatment. It also explores the associations of testosterone deficiency with organ systems and their diseases e.g diabetes, osteoporosis.

Diabetes Associated with Single Gene Defects and Chromosomal Abnormalities

Diabetes Associated with Single Gene Defects and Chromosomal Abnormalities PDF Author: Fabrizio Barbetti
Publisher:
ISBN: 9783318060249
Category : Chromosome abnormalities
Languages : en
Pages : 0

Book Description
This volume, written by renowned experts, provides complete coverage of the main genetic conditions associated with diabetes. Divided into five sections, it offers insights into genetic defects involving the pancreatic beta cell, extreme insulin resistance, ciliopathies, obesity and glucose metabolism, chromosomal defects, and other genetic conditions associated with increased susceptibility to diabetes. Other topics include the various subtypes of monogenic diabetes, such as the neonatal form and the Wolfram syndrome, as well as chromosomal defects leading to complex conditions affiliated with diabetes, like Trisomy 21 or Prader-Willi syndrome. There are also chapters dedicated to the poorly explored relationships between metabolism and neurodegenerative disorders like Friedreich's ataxia and muscular dystrophy. This book is a reference for every pediatric and adult endocrinologist and diabetologist, even experienced ones, with an interest in the intricacies and protean aspects of disorders of glucose metabolism secondary to genetic diseases.

Osteoporosis in Men

Osteoporosis in Men PDF Author: Eric S. Orwoll
Publisher: Academic Press
ISBN: 0080923461
Category : Medical
Languages : en
Pages : 764

Book Description
Since the publication of the first edition, the U.S. Surgeon General released the first-ever report on bone health and osteoporosis in October 2004. This report focuses even more attention on the devastating impact osteoporosis has on millions of lives. According to the National Osteoporosis Foundation, 2 million American men have osteoporosis, and another 12 million are at risk for this disease. Yet despite the large number of men affected, the lack of awareness by doctors and their patients puts men at a higher risk that the condition may go undiagnosed and untreated. It is estimated that one-fifth to one-third of all hip fractures occur in men. This second edition brings on board John Bilezikian and Dirk Vanderschueren as editors with Eric Orwoll. The table of contents is more than doubling with 58 planned chapters. The format is larger – 8.5 x 11. This edition of Osteoporosis in Men brings together even more eminent investigators and clinicians to interpret developments in this growing field, and describe state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy. - Brings together more eminent investigators and clinicians to interpret developments in this growing field - Describes state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy - There is no book on the market that covers osteoporosis in men as comprehensively as this book

Testosterone for Life: Recharge Your Vitality, Sex Drive, Muscle Mass, and Overall Health

Testosterone for Life: Recharge Your Vitality, Sex Drive, Muscle Mass, and Overall Health PDF Author: Abraham Morgentaler
Publisher: McGraw Hill Professional
ISBN: 007164251X
Category : Health & Fitness
Languages : en
Pages : 217

Book Description
"Dr. Morgentaler, an internationally recognized expert in sexual medicine and male hormones, shares his secrets for a healthy life." --Irwin Goldstein, M.D., Director of Sexual Medicine, Alvarado Hospital, San Diego, and Editor-in-Chief, Journal of Sexual Medicine "A highly valuable resource. Finally debunks many of the myths about testosterone's safety, which has been an impediment to its appropriate usage for far too long." --David E. Greenberg, M.D., President, Canadian Society for the Study of the Aging Male From a Harvard doctor and a leading expert on testosterone--the groundbreaking book that shows you how to raise your testosterone levels--and live your life to the fullest Better sex. Increased vitality. More muscle. Improved health. Greater mental agility. These are just a few of the life-enhancing benefits that men with low levels of testosterone can experience when they increase their testosterone level. If you've noticed a decrease in your sex drive; experienced erectile dysfunction; or felt tired, depressed, and unmotivated, this authoritative, up-to-date guide from an expert at Harvard Medical School will help you determine if you have low testosterone--a surprisingly common but frequently undiagnosed condition among middle-aged men. Learn how to: Recognize the symptoms of low testosterone Diagnose the problem with simple tests Find the treatment that's right for you Explore options your doctor might not know about Reduce your risk of cardiovascular disease and obesity

Controversies in Testosterone Deficiency

Controversies in Testosterone Deficiency PDF Author: John P. Mulhall
Publisher: Springer Nature
ISBN: 3030771113
Category : Medical
Languages : en
Pages : 142

Book Description
This book aims to address a number of controversies concerning the use of testosterone treatment. It explains topics that clinicians regularly encounter such as whether to use free or total testosterone in the evaluation of the patient with testosterone deficiency; what factors actually impact testosterone levels, polycythemia, gynecomastia, bone density, and hyperprolactinemia in the testosterone deficient patient; critical analysis of the numerous questionnaires that are available to clinicians; and the impact of testosterone therapy on male fertility, cardiovascular disease, and prostate events including prostate cancer. Guiding the reader in both evaluation and management, the book also illuminates novel concepts in the T space such as testosterone use in the transgender population, T therapy as an endothelial modulator, bipolar testosterone therapy in the patient with advanced prostate cancer, and testosterone therapy as a performance enhancer. Controversies in Testosterone Deficiency is intended for any clinician involved in the care of patients with testosterone deficiency, exploring hot topics and correcting existent misinformation in the routine care of patients.