Author:
Publisher:
ISBN:
Category : Heterocyclic compounds
Languages : en
Pages : 554

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Book Description

Author: Orazio A. Attanasi
Publisher: Royal Society of Chemistry
ISBN:
Category : Medical
Languages : en
Pages : 466

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Book Description
It is well-known that heterocyclic derivatives represent almost half of the several million chemical species discovered to date. The importance of these compounds in many branches of chemistry ensures further investigation and attention. This series aims to stimulate creativity and innovation by including research by leading authorities. In addition to highlights of interesting developments in specific areas, there are also comprehensive reviews reporting the overall state-of-the-art. "Targets in Heterocyclic Systems Volume 4" will be welcomed by researchers and industrialists with an interest in the synthesis and reactivity of heterorings.

Author:
Publisher:
ISBN:
Category : Heterocyclic compounds
Languages : en
Pages : 420

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Book Description

Author: Om Silakari
Publisher: Elsevier
ISBN: 0081021054
Category : Science
Languages : en
Pages : 438

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Book Description
Key Heterocycle Cores for Designing Multitargeting Molecules provides a helpful overview of current developments in the field. Following a detailed introduction to the manipulation of heterocycle cores for the development of dual or multitargeting molecules, the book goes on to describe specific examples of such developments, focusing on compounds such as Benzimidazole, Acridine, Flavones, Thiazolidinedione and Oxazoline. Drawing on the latest developments in the field, this volume provides a valuable guide to current approaches in the design and development of molecules capable of acting on multiple targets. Adapting the heterocyclic core of a single-target molecule can facilitate its development into an agent capable of acting on multiple targets. Such multi-targeting drugs have the potential to become essential components in the design of novel, holistic treatment plans for complex diseases, making the design of such active agents an increasingly important area of research. - Emphasizes the chemical development of heterocyclic nuclei, from single to multitargeting molecules - Provides chapter-by-chapter coverage of the key heterocyclic compounds used in synthesizing multitargeting agents - Outlines current trends and future developments in multitarget molecule design for the treatment of various diseases

Author: Navjeet Kaur
Publisher: Elsevier
ISBN: 0128202831
Category : Science
Languages : en
Pages : 528

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Book Description
Metal and Nonmetal Assisted Synthesis of Six-Membered Heterocycles provides a useful guide to key approaches being explored in this area. The volume highlights synthetic approaches and catalytic options that facilitate the construction of multiple substituted molecules under mild conditions from easily available starting substrates. Drawing on the experience of its expert author, the book is a useful guide on the key approaches being explored in this area. Following a user-friendly structure based on specific six-membered heterocycle ring groups, this volume highlights synthetic approaches and catalytic options that facilitate the construction of multiple substituted molecules under mild conditions from easily available starting substrates. - Highlights new methodologies for the synthesis of different six-membered heterocycles - Provides an up-to-date overview of this fast-moving field with an easy-to-use structure - Includes novel approaches used in the study and application of catalysts in synthetic organic reactions

Author: Orazio A. Attanasi
Publisher:
ISBN: 9788886208567
Category : Science
Languages : en
Pages : 0

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Book Description
Volume 11 keeps the international standard of the THS series, covering the synthesis, reactivity, activity (including medicinal) and mass spectrometry of different systems.

Author: Kristian Nylund
Publisher:
ISBN: 9781608763689
Category : Heterocyclic compounds
Languages : en
Pages : 0

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Book Description
Heterocyclic compounds are organic compounds containing at least one atom of carbon, and at least one element other than carbon, such as sulphur, oxygen or nitrogen within a ring structure. These structures may comprise either simple aromatic rings or non-aromatic rings. Some examples are pyridine (C5H5N), pyrimidine (C4H4N2) and dioxane (C4H8O2). Many heterocyclic compounds, including some amines, are carcinogenic. This book details the proposed mechanisms of Gewald-like reactions and the wide scope of substituted 2-aminothiophenes for real life applications. Literary information about synthesis methods, structure, physical-chemical and biological properties is summarised, and also information about conversion of adamantyl-1 and adamantyl-2 imidazole and benzimidazole derivatives is given. In addition, 3-acetylindole derivatives have been in the centre of attention of researchers over many years due to the high practical value of these compounds. This book presents a survey of the literature on 3-acetylindoles chemistry and provides useful and up-to-date data for medicinal chemists.

Author:
Publisher: Academic Press
ISBN: 0128209860
Category : Science
Languages : en
Pages : 306

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Book Description
Advances in Heterocyclic Chemistry, Volume 133 is the latest release in this definitive series of great importance to organic chemists, polymer chemists, and many biological scientists. Because biology and organic chemistry increasingly intersect, the associated nomenclature also is being used more frequently in explanations. Written by established authorities in the field from around the world, this comprehensive review contains comprehensive chapters on Organosilicon azoles: Structure, silylotropy and NMR spectroscopy, Recent advances in the Nenitzescu indole synthesis (1990–2019), One-pot reactions of three-membered rings giving N,O,S-heterocycles, Organometallic complexes of functionalized chelating azines: Part 2, and more. Presents the definitive serial in the field of heterocyclic chemistry Serves as the go-to reference for organic chemists, polymer chemists and many biological scientists Provides the latest comprehensive reviews as written by established authorities in the field Combines descriptive synthetic chemistry and mechanistic insight to enhance understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds

Author: United States. Public Health Service. Office of the Surgeon General
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 728

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Book Description
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Author: Julio Alvarez-Builla
Publisher: John Wiley & Sons
ISBN: 3527332014
Category : Science
Languages : en
Pages : 2531

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Book Description
Eine Fülle von Information zum attraktiven Preis bietet Ihnen dieses vierbändige Handbuch der Heterocyclenchemie.