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Targeting Wnt Signaling in Cancer

Targeting Wnt Signaling in Cancer PDF Author: Michael Kahn
Publisher: Mdpi AG
ISBN: 9783036535173
Category : Medical
Languages : en
Pages : 0

Book Description
Dysregulation of Wnt signaling is known to be associated with various cancers. As such, identification of novel Wnt pathway targets in cancer and better characterization of already-known targets present exciting, emerging opportunities for cancer treatment. In this Special Issue, we feature papers which discuss the role of Wnt signaling and associated targets in cancer metabolism, tumor immune response, and tumor microenvironment. Papers discussing a range of Wnt-mediated cancers, including those of the colon, liver, pancreas, synovium, bladder, etc., are included.

Targeting Wnt Signaling in Cancer

Targeting Wnt Signaling in Cancer PDF Author: Michael Kahn
Publisher: Mdpi AG
ISBN: 9783036535173
Category : Medical
Languages : en
Pages : 0

Book Description
Dysregulation of Wnt signaling is known to be associated with various cancers. As such, identification of novel Wnt pathway targets in cancer and better characterization of already-known targets present exciting, emerging opportunities for cancer treatment. In this Special Issue, we feature papers which discuss the role of Wnt signaling and associated targets in cancer metabolism, tumor immune response, and tumor microenvironment. Papers discussing a range of Wnt-mediated cancers, including those of the colon, liver, pancreas, synovium, bladder, etc., are included.

Cellular and Molecular Pathogenesis

Cellular and Molecular Pathogenesis PDF Author: Alphonse E. Sirica
Publisher: Lippincott Williams & Wilkins
ISBN:
Category : Medical
Languages : en
Pages : 584

Book Description
The major emphasis in this text is on cellular and molecular pathogenesis in relation to important areas of general pathology, with a focus throughout on elucidating basic mechanisms of disease at the cellular, biochemical and molecular levels.

Cocrystal Applications in Drug Delivery

Cocrystal Applications in Drug Delivery PDF Author: Andrea Erxleben
Publisher: MDPI
ISBN: 3039439839
Category : Science
Languages : en
Pages : 172

Book Description
In 2015, the first pharmaceutical cocrystal was approved by the FDA. Since then, the number of cocrystals on the market and in the development pipeline has been slowly but steadily growing. It is now well established that cocrystals are a versatile new approach to oral drug formulation. This Reprint Book is a collection of articles that show the utility of pharmaceutical cocrystals and various aspects of cocrystal research: • Cocrystals as a strategy to modify the physicochemical properties of a drug such as dissolution behaviour, tabletability, and melting point; • Development of new coformers; • Screening studies for multiple cocrystal forms; • Cocrystals in nano-sized drug delivery.

Indicators of milk and beef quality

Indicators of milk and beef quality PDF Author: J.F. Hocquette
Publisher: BRILL
ISBN: 9086865372
Category : Technology & Engineering
Languages : en
Pages : 464

Book Description
"The farming and agri-food sectors are faced with an increasing demand by consumers for high-quality products. The current major questions are thus how to define quality, and how to increase the quality of animal products to satisfy these new requirements. This is the reason why the Cattle Commission of the European Association of Animal Production (EAAP) organised a specific session on this topic at its Annual Meeting which was held in Bled (Slovenia) in September 2004. This session dealt with the manipulation and evaluation of bovine milk and meat composition and quality with various indicators (commercial, physical, biochemical, molecular or other). These indicators are any method, biological trait, or physical property which may be useful to predict a quality trait. Quality includes sensory traits, nutritional properties of products, their ability to be processed and also any consideration about traceability (genetic, geographic or nutritional traceability). Thus, the full spectrum of quality attributes are discussed. Indicators may also be considered as predictors. In this respect, contributors discussed the detection early in life of the ability of animals to produce meat or milk of high quality. Indicators may also be useful for consumers when they buy meat or milk as official or commercial signs of quality. All the review papers and the short communications which were presented in this session will be in this EAAP publication entitled ""Indicators of milk and beef quality"". Additional papers either presented in 2003 in the EAAP Annual Meeting or from invited authors were added to complete the publication."

The Resource Curse

The Resource Curse PDF Author: Syed Mansoob Murshed
Publisher: Agenda Publishing
ISBN:
Category : Business & Economics
Languages : en
Pages : 172

Book Description
The "resource curse," or "paradox of plenty," refers to the long-established notion central in development economics that countries rich in natural resources, particularly minerals and fuels, perform less well economically than countries with fewer natural resources. In other words, resources are an economic curse rather than a blessing. This short primer explores the complexities of this idea and the debates that surround it, in particular under what conditions the resource curse might operate, if not universal. Discussion ranges over the nature of resource booms, the benefits and costs of export-led growth, the problems of deindustrialization and manufacturing base erosion, rent-seeking behavior and corruption, and the empirical evidence of the effects of natural resource dependence on growth. The treatment is nontechnical and accessible, drawing throughout on a range of illustrative examples from across the developed and developing world. The Resource Curse offers an authoritative introduction to one of the most perplexing issues of economic growth.

Computational Methods for the Analysis of Genomic Data and Biological Processes

Computational Methods for the Analysis of Genomic Data and Biological Processes PDF Author: Francisco A. Gómez Vela
Publisher: MDPI
ISBN: 3039437712
Category : Medical
Languages : en
Pages : 222

Book Description
In recent decades, new technologies have made remarkable progress in helping to understand biological systems. Rapid advances in genomic profiling techniques such as microarrays or high-performance sequencing have brought new opportunities and challenges in the fields of computational biology and bioinformatics. Such genetic sequencing techniques allow large amounts of data to be produced, whose analysis and cross-integration could provide a complete view of organisms. As a result, it is necessary to develop new techniques and algorithms that carry out an analysis of these data with reliability and efficiency. This Special Issue collected the latest advances in the field of computational methods for the analysis of gene expression data, and, in particular, the modeling of biological processes. Here we present eleven works selected to be published in this Special Issue due to their interest, quality, and originality.

Forest Pathology and Entomology

Forest Pathology and Entomology PDF Author: Salvatore Moricca
Publisher: Mdpi AG
ISBN: 9783036526591
Category : Nature
Languages : en
Pages : 330

Book Description
The 22 papers that make up this Special Issue deal with pathogen and pest impact on forest health, from the diagnosis to the surveillance of causative agents, from the study of parasites' biological, epidemiological, and ecological traits to their correct taxonomy and classification, and from disease and pest monitoring to sustainable control strategies.

Duty and Desire Book Club Edition

Duty and Desire Book Club Edition PDF Author: Anju Gattani
Publisher:
ISBN: 9781953100092
Category :
Languages : en
Pages : 344

Book Description
To uphold family honor and tradition, Sheetal Prasad is forced to forsake the man she loves and marry playboy millionaire Rakesh Dhanraj while the citizens of Raigun, India, watch in envy. On her wedding night, however, Sheetal quickly learns that the stranger she married is as cold as the marble floors of the Dhanraj mansion. Forced to smile at family members and cameras and pretend there's nothing wrong with her marriage, Sheetal begins to discover that the family she married into harbors secrets, lies and deceptions powerful enough to tear apart her world. With no one to rely on and no escape, Sheetal must ally with her husband in an attempt to protect her infant son from the tyranny of his family.sion.

Tile & Till

Tile & Till PDF Author:
Publisher:
ISBN:
Category : Pharmacy
Languages : en
Pages : 536

Book Description


Yvain

Yvain PDF Author: Chretien de Troyes
Publisher: Yale University Press
ISBN: 0300038380
Category : Poetry
Languages : en
Pages : 244

Book Description
A twelfth-century poem by the creator of the Arthurian romance describes the courageous exploits and triumphs of a brave lord who tries to win back his deserted wife's love