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Author: Marinus te Pas Publisher: John Wiley & Sons ISBN: 0470962968 Category : Science Languages : en Pages : 340
Book Description
Systems Biology is an interdisciplinary approach to the study of life made possible through the explosion of molecular data made available through the genome revolution and the simultaneous development of computational technologies that allow us to interpret these large data sets. Systems Biology has changed the way biological science views and studies life and has been implemented in research efforts across the biological sciences. Systems Biology and Livestock Science will be the first book to review the latest advances using this research methodology in efforts to improve the efficiency, health, and quality of livestock production. Systems Biology and Livestock Science opens with useful introductory chapters explaining key systems biology principles. The chapters then progress to look at specific advances in fields across livestock science. Coverage includes, but is not limited to, chapters on systems biology approaches to animal nutrition, reproduction, health and disease, and animal physiology. Written by leading researchers in the field, Systems Biology and Livestock Science, will be an invaluable resource to researchers, professionals, and advance students working in this rapidly developing discipline.
Author: Marinus te Pas Publisher: John Wiley & Sons ISBN: 0470962968 Category : Science Languages : en Pages : 340
Book Description
Systems Biology is an interdisciplinary approach to the study of life made possible through the explosion of molecular data made available through the genome revolution and the simultaneous development of computational technologies that allow us to interpret these large data sets. Systems Biology has changed the way biological science views and studies life and has been implemented in research efforts across the biological sciences. Systems Biology and Livestock Science will be the first book to review the latest advances using this research methodology in efforts to improve the efficiency, health, and quality of livestock production. Systems Biology and Livestock Science opens with useful introductory chapters explaining key systems biology principles. The chapters then progress to look at specific advances in fields across livestock science. Coverage includes, but is not limited to, chapters on systems biology approaches to animal nutrition, reproduction, health and disease, and animal physiology. Written by leading researchers in the field, Systems Biology and Livestock Science, will be an invaluable resource to researchers, professionals, and advance students working in this rapidly developing discipline.
Author: Marian Walhout Publisher: Academic Press ISBN: 012385945X Category : Science Languages : en Pages : 553
Book Description
This book provides an entry point into Systems Biology for researchers in genetics, molecular biology, cell biology, microbiology and biomedical science to understand the key concepts to expanding their work. Chapters organized around broader themes of Organelles and Organisms, Systems Properties of Biological Processes, Cellular Networks, and Systems Biology and Disease discuss the development of concepts, the current applications, and the future prospects. Emphasis is placed on concepts and insights into the multi-disciplinary nature of the field as well as the importance of systems biology in human biological research. Technology, being an extremely important aspect of scientific progress overall, and in the creation of new fields in particular, is discussed in 'boxes' within each chapter to relate to appropriate topics. - 2013 Honorable Mention for Single Volume Reference in Science from the Association of American Publishers' PROSE Awards - Emphasizes the interdisciplinary nature of systems biology with contributions from leaders in a variety of disciplines - Includes the latest research developments in human and animal models to assist with translational research - Presents biological and computational aspects of the science side-by-side to facilitate collaboration between computational and biological researchers
Author: Institute of Medicine Publisher: National Academies Press ISBN: 0309219396 Category : Science Languages : en Pages : 570
Book Description
Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.
Author: Marinus te Pas Publisher: John Wiley & Sons ISBN: 0813811740 Category : Science Languages : en Pages : 340
Book Description
Systems Biology is an interdisciplinary approach to the study of life made possible through the explosion of molecular data made available through the genome revolution and the simultaneous development of computational technologies that allow us to interpret these large data sets. Systems Biology has changed the way biological science views and studies life and has been implemented in research efforts across the biological sciences. Systems Biology and Livestock Science will be the first book to review the latest advances using this research methodology in efforts to improve the efficiency, health, and quality of livestock production. Systems Biology and Livestock Science opens with useful introductory chapters explaining key systems biology principles. The chapters then progress to look at specific advances in fields across livestock science. Coverage includes, but is not limited to, chapters on systems biology approaches to animal nutrition, reproduction, health and disease, and animal physiology. Written by leading researchers in the field, Systems Biology and Livestock Science, will be an invaluable resource to researchers, professionals, and advance students working in this rapidly developing discipline.
Author: Neil D. Lawrence Publisher: ISBN: Category : Computers Languages : en Pages : 384
Book Description
Tools and techniques for biological inference problems at scales ranging from genome-wide to pathway-specific. Computational systems biology unifies the mechanistic approach of systems biology with the data-driven approach of computational biology. Computational systems biology aims to develop algorithms that uncover the structure and parameterization of the underlying mechanistic model--in other words, to answer specific questions about the underlying mechanisms of a biological system--in a process that can be thought of as learning or inference. This volume offers state-of-the-art perspectives from computational biology, statistics, modeling, and machine learning on new methodologies for learning and inference in biological networks.The chapters offer practical approaches to biological inference problems ranging from genome-wide inference of genetic regulation to pathway-specific studies. Both deterministic models (based on ordinary differential equations) and stochastic models (which anticipate the increasing availability of data from small populations of cells) are considered. Several chapters emphasize Bayesian inference, so the editors have included an introduction to the philosophy of the Bayesian approach and an overview of current work on Bayesian inference. Taken together, the methods discussed by the experts in Learning and Inference in Computational Systems Biology provide a foundation upon which the next decade of research in systems biology can be built. Florence d'Alch e-Buc, John Angus, Matthew J. Beal, Nicholas Brunel, Ben Calderhead, Pei Gao, Mark Girolami, Andrew Golightly, Dirk Husmeier, Johannes Jaeger, Neil D. Lawrence, Juan Li, Kuang Lin, Pedro Mendes, Nicholas A. M. Monk, Eric Mjolsness, Manfred Opper, Claudia Rangel, Magnus Rattray, Andreas Ruttor, Guido Sanguinetti, Michalis Titsias, Vladislav Vyshemirsky, David L. Wild, Darren Wilkinson, Guy Yosiphon
Author: National Research Council Publisher: National Academies Press ISBN: 0309035422 Category : Technology & Engineering Languages : en Pages : 136
Book Description
Authored by an integrated committee of plant and animal scientists, this review of newer molecular genetic techniques and traditional research methods is presented as a compilation of high-reward opportunities for agricultural research. Directed to the Agricultural Research Service and the agricultural research community at large, the volume discusses biosciences research in genetic engineering, animal science, plant science, and plant diseases and insect pests. An optimal climate for productive research is discussed.
Author: Anupam Nath Jha Publisher: Bentham Science Publishers ISBN: 9815165623 Category : Science Languages : en Pages : 335
Book Description
This book explores the intricate world of livestock sciences and production through the lens of systems biology. Offering a comprehensive exploration of both fundamental and advanced aspects, it unearths the potential of systems biology in the realm of livestock. The book presents 13 edited chapters on cutting-edge knowledge about systems biology and omics technology, showcasing genomics, transcriptomics, proteomics, metabolomics, and more. It illuminates the role of systems biology in livestock and disease management. Readers will learn about power of technologies that merge computational biology, nanobiotechnology, artificial intelligence, and single-cell sequencing. Each chapter is written by scientific experts and includes references for further reading. The book covers 4 key themes: Introduction to Systems Biology in Livestock Science: Uncover the foundation of integrating systems biology with omics data for animal scientists. Multi-scale Modeling Techniques: Explore how multi-scale modeling is shaping the future of system biology. Livestock Viral Diseases: Gain insights into how systems biology is revolutionizing our understanding of livestock viral diseases. Single Cell RNA-Sequencing: Understand the potential of this advanced technique in studying livestock animals at a cellular level. This book is a timely resource for students and researchers, offering a pathway to comprehend the crucial role systems biology plays in sustainable livestock production and management.
Author: Sukanta Mondal Publisher: Academic Press ISBN: 0128206128 Category : Science Languages : en Pages : 340
Book Description
Advances in Animal Genomics provides an outstanding collection of integrated strategies involving traditional and modern - omics (structural, functional, comparative and epigenomics) approaches and genomics-assisted breeding methods which animal biotechnologists can utilize to dissect and decode the molecular and gene regulatory networks involved in the complex quantitative yield and stress tolerance traits in livestock. Written by international experts on animal genomics, this book explores the recent advances in high-throughput, next-generation whole genome and transcriptome sequencing, array-based genotyping, and modern bioinformatics approaches which have enabled to produce huge genomic and transcriptomic resources globally on a genome-wide scale. This book is an important resource for researchers, students, educators and professionals in agriculture, veterinary and biotechnology sciences that enables them to solve problems regarding sustainable development with the help of current innovative biotechnologies. - Integrates basic and advanced concepts of animal biotechnology and presents future developments - Describes current high-throughput next-generation whole genome and transcriptome sequencing, array-based genotyping, and modern bioinformatics approaches for sustainable livestock production - Illustrates integrated strategies to dissect and decode the molecular and gene regulatory networks involved in complex quantitative yield and stress tolerance traits in livestock - Ensures readers will gain a strong grasp of biotechnology for sustainable livestock production with its well-illustrated discussion
Author: Burim N. Ametaj Publisher: Springer ISBN: 3319430335 Category : Science Languages : en Pages : 281
Book Description
This book summarizes the results achieved so far by application of various biological systems (including genomics, transcriptomics, proteomics, and metabolomics) involved in the pathomechanisms and early diagnosis of periparturient diseases as specific biomarkers of disease in cattle. These emerging technologies help to extensively enhance our understanding of the etiology and pathogenesis of periparturient diseases of transition dairy cows. The book includes a chapter dedicated to ‘omics’ sciences and one that discusses the myths established in animal and veterinary sciences in recent decades and emerging, new paradigms. The diseases discussed include metritis, mastitis, laminitis, ketosis, rumen acidosis, periparturient immunosuppression, gastrointestinal microbiota and their involvement in disease, infertility, fatty liver, milk fever, and retained placenta. This book is intended for academics, veterinarians, animal nutritionists, researchers, and graduate students working in the field of ‘omics sciences’ with a special interest in dairy cattle health.
Author: Wilhelm Holzapfel Publisher: Elsevier Health Sciences ISBN: 0444509267 Category : Medical Languages : en Pages : 528
Book Description
The complexity of the microbial population of the animal gastro-intestinal trac has been recognised long ago. However, thus far, investigations have been limited to a few major groups, considered to be dominating, and pathogens that are detrimental and may case diseases and concomitant financial losses in the production animal. Thanks to the latest developments, including improved micriological detection and sampling techniques, and the application of molecular tools to monitor the presence of specific strains in the intestine, our knowlede has increased rapidly in recent years. In addition, new approaches towards improving and/or stabilising animal health, are addressed, with special emphasis on probiotics, and also with regard to the use selected bacterial strains as vehicles for delivery of pharmaceutically active compounds to the muscosa. The book is unique in several respects, not only by its coverage of an extremely wide area in animal gut microbiology, but also by the fact that production animals such as fish and reindeer are included. Scope and treatment of the subject matter and the kind of information that can be found in the volume: Colonisation and development (succession), and mucosal surface composition of the normal microbial population flora in the healthy animal are addressed, whilst estensive information is given on diverse and dominating bacterial populations of different animal types. Reference is also made to those microbial groups considered to be of special benefit to the health and immune protection of the (young) animal bacteria. The development and application of models of the Gastro-Intestinal tract provides a solid basis for studying gut microbial interactions, whilst molecular approaches and the us of molecular tools to monitor the presence of specific strains in the intestine is treated in a comprehensive manner. Wide coverage of different animal types and their gut microbial ecology Extensive and partly new information on the major microbial groups associated with the animal gastro-intestinal tract The book is unique and partly new information and up-to-date information proved in the chapters as a whole
Author: Marinus te Pas
Author: Marinus te Pas
Author: Marian Walhout
Author: Institute of Medicine
Author: Marinus te Pas
Author: Neil D. Lawrence
Author: National Research Council
Author: Anupam Nath Jha
Author: Sukanta Mondal
Author: Burim N. Ametaj
Author: Wilhelm Holzapfel