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Author: Pamela A. Raymond Publisher: Springer Science & Business Media ISBN: 146847281X Category : Science Languages : en Pages : 194
Book Description
It is appropriate at the outset of this book to pose a question that was often asked --of the organizers before the meeting took place and later among those who participated in the meeting -- "What is meant by 'Systems Approaches' in the study of developmental neurobiology?" The answer, as we originally conceived it, can be succinctly summarized by the word "interactions". That brief epithet was expanded during the general discussion portion of the meeting, where the following definition was offered: "Systems approaches in developmental neurobiology are unified by attention to the emergent properties of the developing system under investigation and by a focus on the aspects of development of the nervous system that depend on interactions among its various elements, be they molecular, intracellular or multicellular. " As opposed to ignoring complexity or trying to wish it away, those of us who utilize a systems approach embrace the principle that complexity is what makes the nervous system special. We have come to recognize that wherever we look, we find interactions which are to be probed and eventually. understood. Even the so-called "simple systems", a term that has been used to describe many invertebrate preparations, are embraced under the above definition, since with further study it is becoming increasing clear that such systems are not as simple as once thought. We also include molecular genetics under the systems rubric. After all, genes regulate other genes which regulate others, and so it goes.
Author: Pamela A. Raymond Publisher: Springer Science & Business Media ISBN: 146847281X Category : Science Languages : en Pages : 194
Book Description
It is appropriate at the outset of this book to pose a question that was often asked --of the organizers before the meeting took place and later among those who participated in the meeting -- "What is meant by 'Systems Approaches' in the study of developmental neurobiology?" The answer, as we originally conceived it, can be succinctly summarized by the word "interactions". That brief epithet was expanded during the general discussion portion of the meeting, where the following definition was offered: "Systems approaches in developmental neurobiology are unified by attention to the emergent properties of the developing system under investigation and by a focus on the aspects of development of the nervous system that depend on interactions among its various elements, be they molecular, intracellular or multicellular. " As opposed to ignoring complexity or trying to wish it away, those of us who utilize a systems approach embrace the principle that complexity is what makes the nervous system special. We have come to recognize that wherever we look, we find interactions which are to be probed and eventually. understood. Even the so-called "simple systems", a term that has been used to describe many invertebrate preparations, are embraced under the above definition, since with further study it is becoming increasing clear that such systems are not as simple as once thought. We also include molecular genetics under the systems rubric. After all, genes regulate other genes which regulate others, and so it goes.
Author: Lynne Bianchi Publisher: Garland Science ISBN: 1351189468 Category : Science Languages : en Pages : 772
Book Description
Developmental Neurobiology tells the extraordinary process of neural development by showing how the scientific discoveries were made and how the hypotheses evolved over time. Each chapter explores the specific mechanisms of development while highlighting the key experiments and methods used to make those discoveries—including descriptions of, and experiments utilizing, both invertebrate and vertebrate animal models. This distinctive approach provides the essential facts while strengthening the reader’s appreciation of the scientific method. Discussions of neurodevelopmental disorders and therapeutic approaches to them will captivate those interested in the more clinical aspects of the field. With its clear illustrations and easy-to-follow writing style, Developmental Neurobiology presents an accessible approach to neural development for undergraduate students.
Author: Robbin Gibb Publisher: Academic Press ISBN: 012804084X Category : Psychology Languages : en Pages : 497
Book Description
The Neurobiology of Brain and Behavioral Development provides an overview of the process of brain development, including recent discoveries on how the brain develops. This book collates and integrates these findings, weaving the latest information with core information on the neurobiology of brain development. It focuses on cortical development, but also features discussions on how the other parts of the brain wire into the developing cerebral cortex. A systems approach is used to describe the anatomical underpinnings of behavioral development, connecting anatomical and molecular features of brain development with behavioral development.The disruptors of typical brain development are discussed in appropriate sections, as is the science of epigenetics that presents a novel and instructive approach on how experiences, both individual and intergenerational, can alter features of brain development. What distinguishes this book from others in the field is its focus on both molecular mechanisms and behavioral outcomes. This body of knowledge contributes to our understanding of the fundamentals of brain plasticity and metaplasticity, both of which are also showcased in this book. - Provides an up-to-date overview of the process of brain development that is suitable for use as a university textbook at an early graduate or senior undergraduate level - Breadth from molecular level (Chapters 5-7) to the behavioral/cognitive level (Chapters 8-12), beginning with Chapters 1-4 providing a historical context of the ideas - Integrates the neurobiology of brain development and behavior, promoting the idea that animal models inform human development - Presents an emphasis on the role of epigenetics and brain plasticity in brain development and behavior
Author: Sacha Baginsky Publisher: Springer Science & Business Media ISBN: 376437439X Category : Science Languages : en Pages : 362
Book Description
This volume aims to provide a timely view of the state-of-the-art in systems biology. The editors take the opportunity to define systems biology as they and the contributing authors see it, and this will lay the groundwork for future studies. The volume is well-suited to both students and researchers interested in the methods of systems biology. Although the focus is on plant systems biology, the proposed material could be suitably applied to any organism.
Author: Susan E. Fahrbach Publisher: Princeton University Press ISBN: 0691150982 Category : Science Languages : en Pages : 318
Book Description
A concise introductory textbook on the development of the nervous system This textbook offers a concise introduction to the exciting field of developmental neuroscience, a discipline concerned with the mechanisms by which complex nervous systems emerge during embryonic growth. Bridging the divide between basic and clinical research, it captures the extraordinary progress that has been achieved in the field. It provides an opportunity for students to apply and extend what they have learned in their introductory biology courses while also directing them to the primary literature. This accessible textbook is unique in that it takes an in-depth look at a small number of key model systems and signaling pathways. The book's chapters logically follow the sequence of human brain development and explain how information obtained from models such as Drosophila and zebrafish addresses topics relevant to this area. Beginning with a brief presentation of methods for studying neural development, the book provides an overview of human development, followed by an introduction to animal models. Subsequent chapters consider the molecular mechanisms of selected earlier and later events, neurogenesis, and formation of synapses. Glial cells and postembryonic maturation of the nervous system round out later chapters. The book concludes by discussing the brain basis of human intellectual disabilities viewed from a developmental perspective. Focusing on the mechanistic and functional, this textbook will be invaluable to biology majors, neuroscience students, and premedical and pre-health-professions students. An accessible introduction to nervous system development Suitable for one-semester developmental neuroscience course Thorough review of key model systems Selective coverage of topics allows professors to personalize courses Investigative reading exercises at the end of each chapter An online illustration package is available to professors
Author: Dante Cicchetti Publisher: University Rochester Press ISBN: 9781878822161 Category : Psychology Languages : en Pages : 428
Book Description
This volume focuses on one of the most prevalent and devastating psychiatric disorders, depression. The contributors apply a developmental analysis to the etiology, course, and sequelae of depression across the lifespan. The effects of depression on multiple domains of functioning, including socio-emotional, social cognitive, and psychobiological, are explored. In addition to the impact of the disorder on the depressed individual, its role on the developmental process in offspring of depressed parents and for families having a depressed member are examined and reviewed. Contributors: BARRY NURCOMBE, PAUL F. COLLINS, RICHARD A. DEPUE, JEFFREY F. COHN, SUSAN B. CAMPBELL, KARLEN LYONS-RUTH, PAMELA M. COLE, CAROLYN ZAHN-WAXLER, JAMES C. COYNE, GERALDINE DOWNEY, JULIE BOERGER, CONSTANCE HAMMEN, E. MARK CUMMINGS, PATRICK R. DAVIES, DONNA T. ROSE, LYN Y. ABRAMSON, JULES R. BEMPORAD and STEVEN J. ROMANO.
Author: William Greenough Publisher: Elsevier ISBN: 0323147844 Category : Nature Languages : en Pages : 506
Book Description
Developmental NeuroPsychobiology reviews a variety of topics related to developmental neuropsychobiology, a discipline that encompasses developmental neuroscience and developmental psychobiology. This book discusses embryonic mechanisms and embryogenesis as well as sexual differentiation of the brain, synaptic plasticity, and parent-offspring relationships. The development of olfactory control over behavior is also discussed. This book is comprised of 16 chapters and begins with an analysis of intrinsic mechanisms, including those underlying expression of pattern information at the cellular level and pattern formation in the vertebrate visual system. The next chapters also deal with pattern, but at a higher order, focusing upon the implications of the establishment of systems and how the sequences whereby these systems become established are manifested in the development of behavior. The morphogenetic role of neurotransmitters in embryonic development is also considered, along with structural and functional sexual dimorphisms in the brain and how steroid hormones alter brain organization. The final chapter evaluates previous models of the forces driving parent-offspring relations and offers an alternative view in which both infant-infant interactions and offspring-parent interactions result in mutually beneficial outcomes. This monograph is intended for advanced workers in the biological and/or psychological sciences.
Author: Dan H. Sanes Publisher: Elsevier ISBN: 0080472494 Category : Science Languages : en Pages : 388
Book Description
Development of the Nervous System, Second Edition has been thoroughly revised and updated since the publication of the First Edition. It presents a broad outline of neural development principles as exemplified by key experiments and observations from past and recent times. The text is organized along a development pathway from the induction of the neural primordium to the emergence of behavior. It covers all the major topics including the patterning and growth of the nervous system, neuronal determination, axonal navigation and targeting, synapse formation and plasticity, and neuronal survival and death. This new text reflects the complete modernization of the field achieved through the use of model organisms and the intensive application of molecular and genetic approaches. The original, artist-rendered drawings from the First Edition have all been redone and colorized to so that the entire text is in full color. This new edition is an excellent textbook for undergraduate and graduate level students in courses such as Neuroscience, Medicine, Psychology, Biochemistry, Pharmacology, and Developmental Biology. - Updates information including all the new developments made in the field since the first edition - Now in full color throughout, with the original, artist-rendered drawings from the first edition completely redone, revised, colorized, and updated
Author: Publisher: Academic Press ISBN: 0128201606 Category : Science Languages : en Pages : 728
Book Description
An ever-growing roster of model organisms is a hallmark of 21st century Developmental Biology. Emerging model organisms are well suited to asking some fascinating and important questions that cannot be addressed using established model systems. And new methods are increasingly facilitating the adoption of new research organisms in laboratories. This volume is written by some of the scientists who have played pivotal roles in developing new models or in significantly advancing tools in emerging systems. - Presents some of the most interesting additions to the core set of model organisms - Contains contributions from people who have developed new model systems or advanced tools - Includes personal stories about how and why model systems were developed
Author: National Research Council Publisher: National Academies Press ISBN: 0309069882 Category : Social Science Languages : en Pages : 610
Book Description
How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.
Author: Pamela A. Raymond
Author: Pamela A. Raymond
Author: Lynne Bianchi
Author: Robbin Gibb
Author: Sacha Baginsky
Author: Susan E. Fahrbach
Author: Dante Cicchetti
Author: William Greenough
Author: Dan H. Sanes
Author: 
Author: National Research Council