Author: Victoria Lynn WildePublisher:
ISBN:
Category :
Languages : en
Pages : 294
Book Description
Synthetic Efforts Toward the Total Synthesis of Bryostatin 1 Emphasis on the C17-C27 Fragment
Author: Victoria Lynn WildeTotal Synthesis of Natural Products
Author: Jie Jack LiPublisher: Springer Science & Business Media
ISBN: 3642340652
Category : Science
Languages : en
Pages : 292
Book Description
'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies developed by the respective authors and their research groups. This text is ideal for graduate and advanced undergraduate students, as well as organic chemists in academia and industry.
The Design, Synthesis, and Evaluation of Novel Bryostatin Analogs
Author: Vishal Anil VermaThe Design, Synthesis and Biological Evaluation of the First Totally Synthetic Bryostatin Analogues
Author: Blaise LippaDissertation Abstracts International
Author: Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 884
Book Description
Anticancer Drug Development
Author: Bruce C. BaguleyPublisher: Elsevier
ISBN: 0080490441
Category : Medical
Languages : en
Pages : 411
Book Description
Here in a single source is a complete spectrum of ideas on the development of new anticancer drugs. Containing concise reviews of multidisciplinary fields of research, this book offers a wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death. Detailed descriptions of sources for new drugs and methods for testing and clinical trial design are also provided. - One work that can be consulted for all aspects of anticancer drug development - Concise reviews of research fields, combined with practical scientific detail, written by internationally respected experts - A wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death - Detailed descriptions of the sources of new anticancer drugs, including combinatorial chemistry, phage display, and natural products - Discussion of how new drugs can be tested in preclinical systems, including the latest technology of robotic assay systems, cell culture, and experimental animal techniques - Hundreds of references that allow the reader to access relevant scientific and medical literature - Clear illustrations, some in color, that provide both understanding of the field and material for teaching
Synthetic and Mechanistic Investigations of Analogues of Bryostatin 1
Author: Stacey Ellen BrennerPublisher:
ISBN:
Category :
Languages : en
Pages : 498
Book Description
Natural Products in Medicinal Chemistry
Author: Stephen HanessianPublisher: John Wiley & Sons
ISBN: 3527676554
Category : Medical
Languages : en
Pages : 652
Book Description
The inspiration provided by biologically active natural products to conceive of hybrids, congeners, analogs and unnatural variants is discussed by experts in the field in 16 highly informative chapters. Using well-documented studies over the past decade, this timely monograph demonstrates the current importance and future potential of natural products as starting points for the development of new drugs with improved properties over their progenitors. The examples are chosen so as to represent a wide range of natural products with therapeutic relevance among others, as anticancer agents, antimicrobials, antifungals, antisense nucleosides, antidiabetics, and analgesics. From the content: * Part I: Natural Products as Sources of Potential Drugs and Systematic Compound Collections * Part II: From Marketed Drugs to Designed Analogs and Clinical Candidates * Part III: Natural Products as an Incentive for Enabling Technologies * Part IV: Natural Products as Pharmacological Tools * Part V: Nature: The Provider, the Enticer, and the Healer
Ruthenium and Palladium Catalysis
Author: Hanbiao YangBioactive Marine Natural Products
Author: Dewan S. BhakuniPublisher: Springer Science & Business Media
ISBN: 1402034849
Category : Science
Languages : en
Pages : 397
Book Description
Bioactive Marine Natural Products is the first book available that covers all aspects of bioactive marine natural products. It fills the void in the literature for bioactive marine natural products. The book covers various aspects of marine natural products and it is hoped that all the major classes of bioactive compounds are included. Different classes of marine organisms and the separation and isolation techniques are discussed. The chemistry and biology of marine toxins, peptides, alkaloids, nucleosides and prostanoids are discussed in detail. Biological, toxicological and clinical evaluations are also dealt with to ensure that the book may be adopted at any stage by any practicing organic chemist or biologist, working in academia or in R and D divisions of pharmaceutical companies. Each chapter in the book includes an abstract to highlight the major points discussed in the text and concluding remarks are given. References to books, monographs, review articles and original papers are provided at the end of each chapter.