Author: Young-Jun ShinPublisher:
ISBN:
Category :
Languages : en
Pages : 744
Book Description
Synthesis of Novel Nonracemic Cyclo-BINOLs and Their Applications. II. A New Traceless Linker for Reverse Direction Solid Phase Peptide Synthesis
Author: Young-Jun ShinDissertation Abstracts International
Author: Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 734
Book Description
American Doctoral Dissertations
Author: Publisher:
ISBN:
Category : Dissertation abstracts
Languages : en
Pages : 776
Book Description
Linker Strategies in Solid-Phase Organic Synthesis
Author: Peter ScottPublisher: John Wiley & Sons
ISBN: 9780470749050
Category : Science
Languages : en
Pages : 706
Book Description
Linker design is an expanding field with an exciting future in state-of-the-art organic synthesis. Ever-increasing numbers of ambitious solution phase reactions are being adapted for solid-phase organic chemistry and to accommodate them, large numbers of sophisticated linker units have been developed and are now routinely employed in solid-phase synthesis. Linker Strategies in Solid-Phase Organic Synthesis guides the reader through the evolution of linker units from their genesis in solid-supported peptide chemistry to the cutting edge diversity linker units that are defining a new era of solid phase synthesis. Individual linker classes are covered in easy to follow chapters written by international experts in their respective fields and offer a comprehensive guide to linker technology whilst simultaneously serving as a handbook of synthetic transformations now possible on solid supports. Topics include: the principles of solid phase organic synthesis electrophile and nucleophile cleavable linker units cyclative cleavage as a solid phase strategy photocleavable linker units safety-catch linker units enzyme cleavable linker units T1 and T2 –versatile triazene linker groups hydrazone linker units benzotriazole linker units phosphorus linker units sulfur linker units selenium and tellurium linker units sulfur, oxygen and selenium linker units cleaved by radical processes silicon and germanium linker units boron and stannane linker units bismuth linker units transition metal carbonyl linker units linkers releasing olefins or cycloolefins by ring-closing metathesis fluorous linker units solid-phase radiochemistry The book concludes with extensive linker selection tables, cataloguing the linker units described in this book according to the substrate liberated upon cleavage and conditions used to achieve such cleavage, enabling readers to choose the right linker unit for their synthesis. Linker Strategies in Solid-Phase Organic Synthesis is an essential guide to the diversity of linker units for organic chemists in academia and industry working in the broad areas of solid-phase organic synthesis and diversity oriented synthesis, medicinal chemists in the pharmaceutical industry who routinely employ solid-phase chemistry in the drug discovery business, and advanced undergraduates, postgraduates, and organic chemists with an interest in leading-edge developments in their field.
Development of a Bismuth Linker for Solid Phase Organic Synthesis
Author: Lars Kyhn RasmussenSynthesis and Characterization of Novel BINOL-based Symmetrical and Asymmetrical Axially Chiral Dendrimers
Author: Adil A. GobouriA Novel Photolabile Traceless Linker
Author: David Michael WhiteheadPublisher:
ISBN:
Category :
Languages : en
Pages : 189
Book Description
Part. 1. Cyclotrimerizations : Applications Towards Synthesis
Author: Ann Nicole FaixApproach to the Synthesis of Chiral 3-alkylcyclohexanones Using Nonracemic Higher Order Cyanocuprate Reagents
Author: Emiliano GarciaIsocyanide-based Multicomponent Reactions
Author: Jonathan G. RudickPublisher: Frontiers Media SA
ISBN: 2889634841
Category :
Languages : en
Pages : 100
Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.