Synthesis of Medium-size Carbocycles and Heterocycles Using Ring Expansion Methodology PDF Download

Author: Charles John McIntyre
Publisher:
ISBN:
Category : Organic cyclic compounds
Languages : en
Pages : 115

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Author: Janine Cossy
Publisher: Springer
ISBN: 3642414702
Category : Science
Languages : en
Pages : 168

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The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field.

Author: Matthias D’hooghe
Publisher: Springer
ISBN: 9783319249582
Category : Science
Languages : en
Pages : 0

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Book Description
The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field. All chapters from Topics in Heterocyclic Chemistry are published Online First with an individual DOI. In references, Topics in Heterocyclic Chemistry is abbreviated as Top Heterocycl Chem and cited as a journal.

Author: Teresa M. V. D. Pinho e Melo
Publisher: John Wiley & Sons
ISBN: 3527832017
Category : Science
Languages : en
Pages : 564

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Heterocycles A must-read handbook on heterocycle chemistry with a focus on sustainability Heterocycles feature prominently in our daily life—they are essential for pharmaceuticals, agrochemicals, and fine chemicals. More, numerous natural, bioactive products contain heterocyclic compounds. As a result, heterocyclic chemistry continues to be one of the most important areas of study in organic chemistry. Heterocycles provides an important reference on a wide range of topics relating to heterocyclic chemistry, with a heavy emphasis on sustainable methods and greener syntheses. The book describes state-of-the-art synthetic methods, such as photochemical reactions, dearomatization reactions, organocatalysis, transition metal catalysis, and biocatalysis. It also covers: Sustainable methods, like flow chemistry, mechanochemistry, and multicomponent synthesis Strategies for the synthesis of heterocyclic macrocycles and medium-sized rings Characterization of heterocyclic compounds Heterocycles is a useful reference for organic chemists, natural products chemists, catalytic chemists, and medicinal chemists in academia and industry.

Author: Carl David Gutsche
Publisher:
ISBN:
Category : Carbon compounds
Languages : en
Pages : 266

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Author: Tina Nicola Grant
Publisher:
ISBN:
Category : Heterocyclic compounds
Languages : en
Pages : 702

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Author: S. Thavaselvan
Publisher:
ISBN: 9781805292470
Category :
Languages : en
Pages : 0

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S. Thavaselvan is a renowned scientist in the field of organic chemistry, particularly in the area of synthesizing annulated carbocycles and heterocycles. In this area of research, he has made significant contributions to the development of new methodologies for the synthesis of complex molecules with diverse biological activities. Synthesis of annulated carbocycles and heterocycles is a challenging task due to the presence of multiple functional groups and the complexity of the reaction pathways involved. However, with the development of new methods and strategies, this area of research has seen rapid growth in recent years. Cyclization reactions, which involve the formation of a ring from a linear precursor, are the most common methods used for the synthesis of annulated carbocycles and heterocycles. These reactions can be catalyzed by a variety of transition metals such as palladium, rhodium, ruthenium, nickel, copper, and iron. The choice of metal catalyst and ligand can significantly influence the outcome of the reaction, particularly with respect to stereoselectivity and regioselectivity. Chiral ligands are used to achieve asymmetric synthesis of annulated carbocycles and heterocycles, while non-chiral ligands are used for stereoselective synthesis. Aromatic and aliphatic compounds can be used as starting materials for the synthesis of these complex molecules, and a range of functional groups including nitrogen, oxygen, and sulfur can be incorporated into the final product. The synthesis of annulated carbocycles and heterocycles can also involve nucleophilic substitution, electrophilic substitution, cross-coupling reactions, ring opening reactions, rearrangement, reduction, and oxidation. Grignard reagents, Sonogashira reaction, Suzuki reaction, and Heck reaction are some of the most commonly used reactions for the synthesis of these compounds. Heteroaromatic compounds such as pyridine, indole, quinoline, pyrimidine, pyrazine, benzofuran, benzothiophene, benzimidazole, isoquinoline, and pyrrole are commonly used as building blocks for the synthesis of annulated carbocycles and heterocycles due to their diverse biological activities. In conclusion, S. Thavaselvan's research in the area of synthesizing annulated carbocycles and heterocycles has contributed significantly to the development of new methodologies for the synthesis of complex molecules with diverse biological activities. The use of different metal catalysts, ligands, and functional groups has enabled the development of efficient and selective synthetic methods for the preparation of these complex molecules.

Author: Janine Cossy
Publisher: Springer
ISBN: 3642414737
Category : Science
Languages : en
Pages : 288

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Book Description
The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field.

Author: Illya Zalessky
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

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Author: Martin Frank
Publisher:
ISBN:
Category : Alicyclic compounds
Languages : en
Pages : 112

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